Prenatal Diagnosis of 4p and 4q Subtelomeric Microdeletion in De Novo Ring Chromosome 4 by Halit Akbas, Naci Cine, Mahmut Erdemoglu, Ahmet Engin Atay, Selda Simsek, Aysegul Turkyilmaz, Mehmet Fidanboy

“…Ring chromosomes are unusual abnormalities that are observed in prenatal diagnosis. …”
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Recombinant Chromosome 4 from a Familial Pericentric Inversion: Prenatal and Adulthood Wolf-Hirschhorn Phenotypes by Francesca Malvestiti, Francesco Benedicenti, Simona De Toffol, Sara Chinetti, Adelheid Höller, Beatrice Grimi, Gertrud Fichtel, Monica Braghetto, Cristina Agrati, Eleonora Bonaparte, Federico Maggi, Giuseppe Simoni, Francesca Romana Grati

“…Pericentric inversion of chromosome 4 can give rise to recombinant chromosomes by duplication or deletion of 4p. …”
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Genotoxicity Assessment of Multispecies Probiotics Using Reverse Mutation, Mammalian Chromosomal Aberration, and Rodent Micronucleus Tests by Yi-Jen Chiu, Mun-Kit Nam, Yueh-Ting Tsai, Chun-Chi Huang, Cheng-Chih Tsai

“…Ames tests, in vitro mammalian chromosome aberration assay, and micronucleus tests in mouse peripheral blood are performed. …”
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Complex Variant of Philadelphia Translocation Involving Chromosomes 9, 12, and 22 in a Case with Chronic Myeloid Leukaemia by F. Malvestiti, C. Agrati, S. Chinetti, A. Di Meco, S. Cirrincione, M. Oggionni, B. Grimi, F. Maggi, G. Simoni, F. R. Grati

“…Chronic myeloid leukemia (CML) is a hematopoietic stem cell disorder included in the broader diagnostic category of myeloproliferative neoplasms, associated with fusion by BCR gene at chromosome 22q11 to ABL1 gene at chromosome 9q34 with the formation of the Philadelphia (Ph) chromosome. …”
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Regions enriched for DNA repeats in chromosomes of Macrostomum mirumnovem, a species with a recent Whole Genome Duplication by K. S. Zadesenets, N. B. Rubtsov

Subjects: “…metaphase chromosome microdissection…”
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Dispensable genome and segmental duplications drive the genome plasticity in Fusarium solani by Abbeah Navasca, Jatinder Singh, Viviana Rivera-Varas, Upinder Gill, Gary Secor, Thomas Baldwin

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Identification of the BBX gene family in blueberry at different chromosome ploidy levels and fruit development and response under stress by Yujian Xue, Jiazhuo Chen, Jia Hao, Xiaoyu Bao, Luodan Kuang, Dong Zhang, Chengwen Zong

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Mapping genomic regions affecting sensitivity to bovine respiratory disease on chromosome X using selective DNA pooling by Ehud Lipkin, Maria Giuseppina Strillacci, Miri Cohen-Zinder, Harel Eitam, Moran Yishay, Morris Soller, Carlotta Ferrari, Alessandro Bagnato, Ariel Shabtay

“…Identification of affecting genes is essential for selection for decrease sensitivity. Chromosome X is a special attractive target for gene mapping in light of reports on both sexual dimorphism in immunity and higher susceptibility of males to this disease. …”
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Chromosome 3p Inverted Duplication with Terminal Deletion: Second Postnatal Case Report with Additional Clinical Features by Jacquelyn D. Riley, Catherine M. Stefaniuk, Francine Erenberg, Angelika L. Erwin, Lauren Palange, Caroline Astbury

“…Microarray analysis revealed a 5.37 Mb deletion of chromosome bands 3p26.1 to 3p26.3 and a 13.68 Mb duplication of 3p24.3 to 3p26.1. …”
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Chromosome 1 Sequence Analysis of C57BL/6J-Chr1KM Mouse Strain by Fuyi Xu, Tianzhu Chao, Yiyin Zhang, Shixian Hu, Yuxun Zhou, Hongyan Xu, Junhua Xiao, Kai Li

“…In this study, we sequenced the genome of the C57BL/6J-Chr1KM (B6-Chr1KM) strain, the chromosome 1 (Chr 1) of which was derived from one KM mouse. …”
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Integrated genomic analysis to reduce chromosomal analysis for the diagnosis of pediatric hematologic malignancies: addressing the shortage of cytogenetic technologists by Dong Li, Sarah K. Tasian, Gerald Wertheim, Susan R. Rheingold, Kathrin M. Bernt, Haley Newman, Luanne Wainwright, Donna M. Wilmoth, Brian Thiel, Lea F. Surrey, Elizabeth Margolskee, Vinodh Pillai, Minjie Luo, Michele E. Paessler, Stephen P. Hunger, Marilyn M. Li, Yiming Zhong

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Assessment of Combined Karyotype Analysis and Chromosome Microarray Analysis in Prenatal Diagnosis: A Cohort Study of 3710 Pregnancies by Jin Wang, Danni Wang, Yan Yin, Yi Deng, Mengling Ye, Ping Wei, Zhuo Zhang, Chun Chen, Shengfang Qin, Xueyan Wang

“…The current study aimed to compare the characteristics of chromosome abnormalities detected by conventional G-banding karyotyping, chromosome microarray analysis (CMA), or fluorescence in situ hybridization (FISH)/CNVplex analysis and further explore the application value of combined karyotype analysis and CMA in prenatal diagnosis with a larger sample size. …”
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A Case of Philadelphia Chromosome Positive Myeloproliferative Neoplasm in a Pregnant Woman with Unusual Primary Myelofibrosis Features by Jason Koshy, Jack Alperin, Bagi Jana, Avi Markowitz, You-Wen Qian

“…However, a diagnostic dilemma arises when Philadelphia chromosome-positive MPNs lack the majority of the typical features seen in CML. …”
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Proportion of Chromosomal Disorders and Their Patterns among Births with Congenital Anomalies in Africa: A Systematic Review and Meta-Analyses by Teshome Gebremeskel Aragie, Girma Seyoum Gedion

“…Worldwide, surveys have shown that the frequency of chromosomal disorders among births with congenital anomalies varies greatly from country to country. …”
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Expanded non-invasive prenatal testing offers better detection of fetal copy number variations but not chromosomal aneuploidies. by Shaozhe Yang, Yuan Zhuang, Junfeng Li, Xiuhong Fu

“…<h4>Conclusion</h4>By enhancing sequencing data, NIPT-plus can effectively screen for CNVs as well as chromosomal aneuploidies. However, NIPT-plus does not have an advantage over standard NIPT in screening for chromosomal aneuploidies.…”
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Identification of microsatellite loci according to BAC sequencing data and their physical mapping to the bread wheat 5B chromosome by M. A. Nesterov, D. A. Afonnikov, E. M. Sergeeva, L. A. Miroshnichenko, M. K. Bragina, A. O. Bragin, G. V. Vasiliev, E. A. Salina

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Development of the genetic classification of Aegilops columnaris Zhuk. chromosomes based on the analysis of introgression lines Triticum aestivum×Ae. columnaris by A. A. Shishkina, A. Yu. Dragovich, A. S. Rouban, S. N. Sibikeev, A. E. Druzhin, E. D. Badaeva

“…In several lines acrocentric and telocentric chromosomes have been revealed (Ae-b and Ae-c). It is most likely that these chromosomes were derived from unknown Aegilops chromosomes due to a large deletion. …”
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Development and characterization of a line with substitution of chromosome 4B of wheat <i>Triticum aestivum</i> L. on chromosome 4H^<i>mar</i> of wild barley <i>Hordeum marinum ssp. gussoneanum (4x)</i> by L. A. Pershina, N. V. Trubacheeva, V. K. Shumny, E. D. Badaeva

“…Genomic in situ hybridization (GISH) revealed a pair of H. marinum chromosomes in the genome of these plants. C­ banding analysis confirmed that bread wheat chromosome 4B was replaced by wild barley chromosome 4Hmar. …”
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The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey) by Øyvind Helgeland, Jens K. Hertel, Anders Molven, Helge Ræder, Carl G. P. Platou, Kristian Midthjell, Kristian Hveem, Ottar Nygård, Pål R. Njølstad, Stefan Johansson

“…Two adjacent regions upstream CDKN2B on chromosome 9p21 have been associated with type 2 diabetes (T2D) and progression of cardiovascular disease (CVD). …”
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Identifying Safeguards Disabled by Epstein-Barr Virus Infections in Genomes From Patients With Breast Cancer: Chromosomal Bioinformatics Analysis by Bernard Friedenson

“…Calculation algorithms to make these comparisons were developed. ResultsChromosome breakpoints in breast and ovarian cancer clustered around breakpoints in EBV-associated cancers. …”
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