Showing 981 - 1,000 results of 1,174 for search '"chromosome"', query time: 0.06s Refine Results
  1. 981

    The Impact of the Metabolic Syndrome Severity on the Appearance of Primary and Permanent DNA Damage by Mirta Milić, Luka Kazensky, Martina Matovinović

    Published 2024-12-01
    “…Unrepaired damage can lead to DNA base changes, chromosomal mutations, genomic loss and instability, and disrupted gene and protein expression. …”
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    Article
  2. 982

    Genome Stability Pathways in Head and Neck Cancers by Glenn Jenkins, Kenneth J. O'Byrne, Benedict Panizza, Derek J. Richard

    Published 2013-01-01
    “…Defective DNA repair generates chromosomal derangement that can cause subsequent alterations in gene expression, and is a hallmark of progression toward carcinoma. …”
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    Article
  3. 983

    Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome by Saba F. Ali, Rebecca J. Sonu, Denis M. Dwyre, Brian A. Jonas, Hooman H. Rashidi

    Published 2015-01-01
    “…Most myelodysplastic syndromes (MDS) present with loss or gain of chromosomal material and less commonly show translocations as a sole abnormality. …”
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    Article
  4. 984

    An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp by Tennille K. Marx, Robin Reddeman, Amy E. Clewell, John R. Endres, Erzsébet Béres, Adél Vértesi, Róbert Glávits, Gábor Hirka, Ilona Pasics Szakonyiné

    Published 2018-01-01
    “…No evidence of genotoxicity was found in a bacterial reverse mutation test (Ames), in an in vitro mammalian chromosomal aberration test, or in an in vivo mouse micronucleus study. …”
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    Article
  5. 985

    Image-Based Face Recognition Techniques Used in Disease Detection Approaches: A Survey by Ghalib Ahmed Salman, Inas Jawad Kadhim, Ahmed Husham Al-Badri

    Published 2024-03-01
    “…These alterations in facial patterns can serve as potential indicators for corresponding diseases, particularly in the fields of endocrinology and metabolism, Muscles-Nervous disorders, Chromosomes, and Genetic disorders, among others. Technologies used in Face Recognition (FR) have been developed over the past few decades; however, only a limited amount of research has been applied in recent years to FR-based disease detection for clinical purposes. …”
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    Article
  6. 986

    Karyotype Patterns of Hypsolebias antenori (Cyprinodontiformes: Rivulidae): An Endangered Killifish of the Semiarid Region of Brazil by Wallace Silva do Nascimento, Juliana Galvão Bezerra, Paulo Augusto Lima-Filho, Maria Emília Yamamoto, Sathyabama Chellappa, Wagner Franco Molina

    Published 2014-01-01
    “…The karyotype of this species is composed of 2n = 48 chromosomes (6m + 4sm + 36st; NF = 96); the heterochromatic regions are located in centromeric or pericentromeric position and are more pronounced in the nucleolar organizer regions. …”
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    Article
  7. 987

    Genome-wide maps of highly-similar intrachromosomal repeats that can mediate ectopic recombination in three human genome assemblies by Luis Fernandez-Luna, Carlos Aguilar-Perez, Christopher M. Grochowski, Michele G. Mehaffey, Claudia M.B. Carvalho, Claudia Gonzaga-Jauregui

    Published 2025-04-01
    “…Summary: Repeated sequences spread throughout the genome play important roles in shaping the structure of chromosomes and facilitating the generation of new genomic variation through structural rearrangements. …”
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    Article
  8. 988

    Diagnosis of Fanconi Anemia: Mutation Analysis by Multiplex Ligation-Dependent Probe Amplification and PCR-Based Sanger Sequencing by Johan J. P. Gille, Karijn Floor, Lianne Kerkhoven, Najim Ameziane, Hans Joenje, Johan P. de Winter

    Published 2012-01-01
    “…A clinical diagnosis of FA needs to be confirmed by testing cells for sensitivity to cross-linking agents in a chromosomal breakage test. As a second step, DNA testing can be employed to elucidate the genetic subtype of the patient and to identify the familial mutations. …”
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    Article
  9. 989

    Cryo-EM structure and evolutionary history of the conjugation surface exclusion protein TraT by Chloe Seddon, Sophia David, Joshua L. C. Wong, Naito Ishimoto, Shan He, Jonathan Bradshaw, Wen Wen Low, Gad Frankel, Konstantinos Beis

    Published 2025-01-01
    “…Unexpectedly, we identify chromosomal TraT homologues from multiple Gram-negative phyla which form numerous divergent lineages in a phylogenetic tree of TraT sequences. …”
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    Article
  10. 990

    Metastatic Malignant Ectomesenchymoma Initially Presenting as a Pelvic Mass: Report of a Case and Review of Literature by A. Nael, P. Siaghani, W. W. Wu, K. Nael, Lisa Shane, S. G. Romansky

    Published 2014-01-01
    “…Cytogenetic analysis of metastatic tumor demonstrated complex karyotype with multiple chromosomal deletions and duplications. The patient received national protocol chemotherapy against neuroblastoma and adjuvant radiotherapy after surgical resection of the cerebellar tumor with good response. …”
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    Article
  11. 991

    FusOn-pLM: a fusion oncoprotein-specific language model via adjusted rate masking by Sophia Vincoff, Shrey Goel, Kseniia Kholina, Rishab Pulugurta, Pranay Vure, Pranam Chatterjee

    Published 2025-02-01
    “…Abstract Fusion oncoproteins, a class of chimeric proteins arising from chromosomal translocations, are major drivers of various pediatric cancers. …”
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    Article
  12. 992

    RCSD1-ABL1 Translocation Associated with IKZF1 Gene Deletion in B-Cell Acute Lymphoblastic Leukemia by Shawana Kamran, Gordana Raca, Kamran Nazir

    Published 2015-01-01
    “…We describe extensive genetic characterization of a case of B-ALL with RCSD1-ABL1 fusion, by using conventional cytogenetic analysis, Fluorescence In Situ Hybridization (FISH) studies, and Chromosomal Microarray Analysis (CMA). The use of CMA resulted in detection of an approximately 70 kb deletion at 7p12.2, which caused a disruption of the IKZF1 gene. …”
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    Article
  13. 993

    The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation by Joshua C. Pritchett, Radu M. Nanau, Manuela G. Neuman

    Published 2012-01-01
    “…(i) To develop a unified list of drugs incriminated in drug-induced hepatotoxicity and severe cutaneous reactions, in which drug hypersensitivity leads to HHV-6 reactivation and further complication of therapy and recovery and (ii) to supplement the already available data on reporting frequencies of liver- or skin-induced cases with knowledge of individual case reports, including HHV-6 reactivation and briefly introducing chromosomally integrated HHV-6. Data Sources and Extraction. …”
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  14. 994

    OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblasts by Mariarosaria De Rosa, Ryan P. Barnes, Ariana C. Detwiler, Prasanth R. Nyalapatla, Peter Wipf, Patricia L. Opresko

    Published 2025-01-01
    “…However, OGG1 activity is essential for preserving cell growth after chronic telomeric 8oxoG formation, whereas MUTYH promotes senescence to prevent chromosomal instability from unrepaired damage. Our studies reveal that inefficient completion of 8oxoG BER at telomeres triggers cellular senescence via SSB intermediates which disrupt telomere function.…”
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  15. 995

    A Review on Major Rust Resistance Gene and Amino Acid Changes on Wheat (Triticum aestivum L) by Bikas Basnet, Philomin Juliana, Keshav Bhattarai, Umisha Upreti

    Published 2022-01-01
    “…In the present review, we provide updated information on all black stem rust, yellow leaf rust, and brown leaf rust resistance genes including chromosomal position, those derived from different sources, nature of resistance type, and amino acid changes done by this gene against rust pathogen. …”
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  16. 996

    In Silico Analysis of Common Long Noncoding RNAs in Schistosoma mansoni and Schistosoma haematobium by Serhat Sirekbasan, Tugba Gurkok Tan

    Published 2021-01-01
    “…A significant number of lncRNAs was determined to be transcribed from sex chromosomes. The frequently expressed lncRNAs appear to be involved in metabolic and biological regulation processes. …”
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    Article
  17. 997

    Implications of the Use of Eukaryotic Translation Initiation Factor 5A (eIF5A) for Prognosis and Treatment of Hepatocellular Carcinoma by Felix H. Shek, Sarwat Fatima, Nikki P. Lee

    Published 2012-01-01
    “…Eukaryotic translation initiation factor 5A (eIF5A) is one of the eIFs involved in translation initiation and eIF5A2, one of its isoforms, is upregulated in various cancers including HCC as a result of chromosomal instability, where it resides. In HCC, eIF5A2 expression is associated with adverse prognosis such as presence of tumor metastasis and venous infiltration. …”
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    Article
  18. 998

    Unravelling single-cell DNA replication timing dynamics using machine learning reveals heterogeneity in cancer progression by Joseph M. Josephides, Chun-Long Chen

    Published 2025-02-01
    “…Our methodology brings critical insights into chromosomal aberrations and highlights the ubiquitous aneuploidy process during tumorigenesis. …”
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    Article
  19. 999

    Major Organic Involvement in Women with Fabry Disease in Argentina by Fernando Perretta, Norberto Antongiovanni, Sebastián Jaurretche

    Published 2018-01-01
    “…Organic involvement in men is well known, but in women it is controversial, partly due to the random X-chromosomes inactivation (Lyon hypothesis). The aim of this study was to describe the organic involvement in women at the time of FD diagnosis. …”
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    Article
  20. 1000

    E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature by Hiren G. Patel, Seme Tabassum, Sohail Shaikh

    Published 2017-01-01
    “…E. coli strains B2 and D produce cyclomodulin toxins as part of their virulence, which interferes with the cell cycle regulation, promoting chromosomal instability, and increasing susceptibility to cancer. …”
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    Article