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921
Base Composition Characteristics of Mammalian miRNAs
Published 2013-01-01“…Mammalian miRNAs are evolutionarily conserved, are scattered throughout chromosomes, and play an important role in the immune response and the onset of cancer. …”
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922
Acral Melanoma: A Review of Its Pathogenesis, Progression, and Management
Published 2025-01-01“…Recent advances in genomic, transcriptomic, and epigenomic sequencing have revealed genetic alterations unique to acral melanoma, including novel driver genes, high copy number variations, and complex chromosomal rearrangements. This review synthesizes the current knowledge on the clinical features, epidemiology, and treatment approaches for acral melanoma, with a focus on the genetic pathogenesis that gives rise to its unique tumor landscape. …”
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923
Intellectual Disability and Blended Phenotypes: Insights from a Centre in North India
Published 2024-01-01“…A confirmatory diagnosis is facilitated by genetic testing like chromosomal microarray and next generation sequencing. …”
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924
More than an Incidentaloma: The Nonreportable NIPT
Published 2022-01-01“…Noninvasive prenatal testing (NIPT), which utilizes a maternal blood sample to detect fetal gender and screen for fetal aneuploidy (abnormal chromosomes), is widely used in obstetrics to screen for Trisomies 21, 18, and 13. …”
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925
Text Knowledge Acquisition Method of Collaborative Product Design Based on Genetic Algorithm
Published 2022-01-01“…According to the operation process of the genetic algorithm, the chromosomes of clustered text are constructed and encoded and the initial population is obtained. …”
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926
Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness
Published 2025-01-01“…The results showed no significant disturbances in reproductive cycles or spermatogenesis, and chromosomal aberration tests showed no mutagenic effects. …”
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927
A Review on Mangrove Actinobacterial Diversity: The Roles of Streptomyces and Novel Species Discovery
Published 2019-05-01“…Streptomycetes are noted to possess several special qualities such as multicellular life cycle and large linearized chromosomes. The significant contribution of Streptomyces in microbial drug discovery as witnessed through the discovery of many important antibiotic drugs has undeniably encourage the exploration of these bacteria from different environments, especially the mangrove environments. …”
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928
Genome rearrangements in neurodevelopmental disorders of the central nervous system: origins, genomic mechanisms, functional and clinical consequences. Review article
Published 2022-03-01“…In our research, the detection of chromosomal aberrations by molecular karyotyping and whole exome sequencing capable of uncovering pathogenic variants in any of the human genes were the main technologies used to identify the molecular causes of intellectual disability. …”
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929
Dandy-Walker Syndrome. Case Report and Literature Review
Published 2022-11-01“…Genetic predisposition associated with malformations and chromosomal alterations has been suggested. The diagnosis can be carried out during the prenatal or postnatal stage, clinically and diagnostic imaging studies. …”
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930
Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes
Published 2024-12-01“…Genetic mutations, chromosomal abnormalities, transcription factors, mutations in tumor suppressor genes, and mutations in oncogenes have all been associated with an increased risk of LC development. …”
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931
Malignant Phyllodes Tumor and Acute Megakaryoblastic Leukemia Sharing a Common Clonal Origin
Published 2013-01-01“…We treated a young female patient with a malignant phyllodes tumor followed by an acute megakaryoblastic leukemia and found several of the same marker chromosomes by karyotype analysis of cells from both the tumor and the leukemia implying a common clonal origin of the two. …”
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932
Congenital Absence of a Teat in a Japanese Black Heifer
Published 2011-01-01“…The heifer had normal chromosomal set. The heifer was culled due to its mammary abnormality. …”
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933
Genome-Wide Identification and Expression Analysis of bHLH-MYC Family Genes from Mustard That May Be Important in Trichome Formation
Published 2025-01-01“…The results revealed that these transcription factors were unevenly distributed across 18 chromosomes, showing relatively consistent conserved motifs and gene structures and high homology. …”
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934
A case-control genome-wide association study of estimated breeding values for resistance to gastrointestinal nematodes in two local dairy sheep breeds
Published 2025-02-01“…As a result, 13 genes on 12 chromosomes and 10 genes on 11 different chromosomes were identified in the Comisana and Massese breed, respectively. …”
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935
Making the Final Cut — Mechanisms Mediating the Abscission Step of Cytokinesis
Published 2010-01-01“…Cytokinesis begins in the early stages of anaphase after the positioning of the cleavage plane and after the chromosomes segregate. This involves the recruitment and assembly of an actomyosin contractile ring, which constricts the plasma membrane and compacts midzone microtubules to form an electron-dense region, termed the midbody, located within an intracellular bridge. …”
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936
Mathematical analysis and modeling of DNA segregation mechanisms
Published 2018-03-01“…The Spindle Assembly Checkpoint (SAC) is an evolutionarily mechanism that delays mitotic progression until all chromosomes are properly linked to the mitotic spindle. …”
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937
Clinicopathological Features of Inflammatory Myofibroblastic Tumor in the Breast
Published 2022-01-01“…The FISH test demonstrated ALK (2p23) chromosomal translocation (ALK positive). The final diagnosis of breast IMT was rendered with nonclassical morphology. …”
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938
Feline Neural Progenitor Cells I: Long-Term Expansion under Defined Culture Conditions
Published 2012-01-01“…Importantly, later passage cNPCs did not develop chromosomal aberrations.…”
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939
Primary Synovial Sarcoma of Kidney: A Rare Differential Diagnosis of Renomegaly
Published 2014-01-01“…Though they have characteristic histology and immunohistochemistry (IHC) due to rarity of incidence it is difficult to diagnose them. Sometimes chromosomal rearrangement studies are required to confirm the diagnosis. …”
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940
Molecular Pathogenesis of MALT Lymphoma
Published 2015-01-01“…Interestingly, at least 3 different, apparently site-specific, chromosomal translocations and missense and frameshift mutations, all pathway-related genes affecting the NF-κB signal, have been implicated in the development and progression of MALT lymphoma. …”
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