Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina) by Gregory Scott, Meghan M. Louis, Julie A. Balko, Claire M. Bublitz, Brigid V. Troan, Ronald E. Baynes, Dustin Smith, Larry J. Minter

“…Plasma was analyzed by ultra-performance liquid chromatography-tandem mass spectrometry. Samples were analyzed individually and reported as a mean of the samples at each timepoint. …”
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Altered O-Glycans in stimulated whole saliva from patients with primary Sjögren’s syndrome and non-pSS sicca by Sarah Kamounah, Kristina A. Thomsson, Christiane Elisabeth Sørensen, Eric Paul Bennett, Niclas G. Karlsson, Anne Marie Lynge Pedersen

“…O-linked oligosaccharides from stimulated whole saliva (SWS) samples from 24 patients with pSS, 38 patients with non-pSS sicca, and 23 healthy controls were analyzed using liquid chromatography mass spectrometer (LC-MS). Non-fractionated reduced and alkylated saliva was dot-blotted to PVDF-membrane and O-linked oligosaccharides were released using reductive beta-elimination. …”
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Quantification of Mineral Oil Aromatic Hydrocarbons (MOAH) in Anhydrous Cosmetics Using 1H NMR by Sandra Weber, Tamina Schmidt, Paul Schumacher, Thomas Kuballa, Gerd Mildau, Stephan G. Walch, Andrea Hartwig, Dirk W. Lachenmeier

“…In preliminary trials using silica gel thin-layer chromatography, the retention behaviour of 21 common aromatic compounds was tested in eluents with different solvent strength including EtOAc, MeOH, cyclohexane, and dichloromethane. …”
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Plasma and Milk Pharmacokinetics and Estimated Milk Withdrawal Time of Tolfenamic Acid in Lactating Sheep by Orhan Corum, Kamil Uney, Devran Coskun, Duygu Durna Corum, Gul Cetin, Muammer Elmas

“…The concentrations of tolfenamic acid in the plasma and milk were determined using high‐pressure liquid chromatography and evaluated using non‐compartmental analysis. …”
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Fat Body Metabolome Revealed Glutamine Metabolism Pathway Involved in Prepupal <i>Apis mellifera</i> Responding to Cold Stress by Xinjian Xu, Mingjie Cao, Chenyu Zhu, Lingqing Mo, Huajiao Huang, Jiaying Xie, Bingfeng Zhou, Shujing Zhou, Xiangjie Zhu

“…In this study, the ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS)-based non-target metabolome was analyzed between the cold-treated (CT, 20 °C, 36 h) and control (CK, 35 °C) fat body in prepupal honeybees. …”
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Material and Technique Analysis of Qing Dynasty Official Style Architectural Polychrome Paintings in Hangzhou, Zhejiang, China by Ling Shen, Dan Hua, Baisu Nan, Yao Yao, Hong Duan, Jiakun Wang

“…Through multi-techniques such as optical microscopy (OM), scanning electron microprobe with energy dispersive X-ray spectroscopy analysis (SEM-EDX), micro-Raman spectroscopy, micro-Fourier Transform Infrared spectroscopy (μ-FTIR), and pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS), it was found that there is a significant difference from the reported common non-ground architectural paintings in the south, typically having four-layer structures with a white base and ground plaster layer in preparation for painting. …”
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Chemical Composition and Antimicrobial Activity of Essential Oil of <i>Camphora glanduliferum</i> ‘Honganzhang’ by Yang Yang, Qiuting Xiang, Yinan Yang, Donglv Shu, Jiawen Yan, Lijun Huang, Xiumei Yang, Jing Peng, Xingliang Chen, Guoqun Yang

“…After extracting <i>C. glanduliferum</i> ’Honganzhang’ essential oils (CGHEO) by steam distillation, gas chromatography-mass spectrometry (GC-MS) was used to analyze its chemical components. …”
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High-Performance Liquid Chromatographic Ultraviolet Determination of Memantine Hydrochloride after In Vitro Transdermal Diffusion Studies by Sergio del Rio-Sancho, César E. Serna-Jiménez, M. Aracely Calatayud-Pascual, Cristina Balaguer-Fernández, Andrés Femenía-Font, Virginia Merino, Alicia López-Castellano

“…The purpose of the present work was to validate an accurate and precise high-performance liquid chromatography (HPLC) method involving ultraviolet detection for the quantitative analysis of memantine hydrochloride. …”
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Analysis of the nutritional and fatty acid profile of sacha inchi tempe (Plukenetia volubilis L.) using different cooking methods by Diana Nur Afifah, Diana Nur Afifah, Daniaty Afifatus Salam, Fitria Nugraheni, Nina Resti, Rachma Purwanti, Gemala Anjani, Mursid Tri Susilo, Nuryanto, Made Astawan, Irma Sarita Rahmawati

“…Moreover, protein, fat, carbohydrates, and fatty acid were evaluated using the Kjeldahl, Soxhlet, difference, and Gas Chromatography (GC) method.ResultsThere were significant differences (p ≤ 0.05) in water content, ash content, protein, saturated fat, unsaturated, and PUFA in fermentation time. …”
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Development and comprehensive greenness assessment of HPLC method for quality control of β-sitosterol in pharmaceutical ointments with trio-color coded evaluation by Haya I. Aljohar, Abdullah M. Al-Hossaini, Seham A. Alzammay, Samiah Alhabardi, Hadir M. Maher, Aya R. Ahmed

“…Abstract A simple, rapid, and reproducible high-performance liquid chromatography (HPLC) method has been developed and validated for the determination of β-sitosterol in the pharmaceutical dosage form of moist exposed burn ointment (MEBO). …”
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Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy by Pei-Pei Liu, Xin-Yue Yu, Qing-Qing Pan, Jia-Jun Ren, Yu-Xuan Han, Kai Zhang, Yan Wang, Yin Huang, Tao Ban

“…Methods: We generated a mouse model of SCM induced by lipopolysaccharide (LPS) and then obtained comprehensive metabolic and genetic data from SCM mouse hearts using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) and RNA sequencing (RNA-seq). …”
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Comprehensive characterization of higher order structure changes in methionine oxidized monoclonal antibodies via NMR chemometric analysis and biophysical approaches by Mingyue Li, Victor A. Beaumont, Shahajahan Akbar, Hannah Duncan, Arch Creasy, Wenge Wang, Kelly Sackett, Lisa Marzilli, Jason C. Rouse, Hai-Young Kim

“…We used a forced degradation method involving concentration-dependent oxidation by peracetic acid, in which Met oxidation is site-specifically quantified by liquid chromatography-mass spectrometry. Conventional biophysical techniques report nuanced results, in which CD detects no change to the secondary structure and little change in the tertiary structure. …”
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Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

“…Metabolomics profiling was performed from plasma samples using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. …”
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Model Analytical Development for Physical, Chemical, and Biological Characterization of Momordica charantia Vegetable Drug by Deysiane Oliveira Brandão, Geovani Pereira Guimarães, Ravely Lucena Santos, Fernando José de Lima Ramos Júnior, Karla Monik Alves da Silva, Fabio Santos de Souza, Rui Oliveira Macêdo

“…The herbal medicine raw material derived from the leaves and fruits in different particle sizes was analyzed using thermoanalytical techniques as thermogravimetry (TG) and differential thermal analysis (DTA), pyrolysis coupled to gas chromatography/mass spectrometry (PYR-GC/MS), and nuclear magnetic resonance (1H NMR), in addition to the determination of antimicrobial activity. …”
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Investigation of 4-Nitro-N, N-diphenylaniline as a chemical tracer under high pressure high temperature reservoir conditions for enhanced oil recovery applications by Subhadip Maiti, Nishant Kumar Choudhary, Kiran R. Gore, Sandeep D. Kulkarni

“…Ultraviolet (UV) and high-performance liquid chromatography (HPLC) techniques were established to measure the ppm-level concentrations of 4-FBA and N-TPA in the standard brine solutions. …”
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Aroma profiling of long shelf-life yoghurt from milk with varying acidity: Insights from sensory evaluation and instrumental analysis by Jia Wang, Dongjie Zhang, Jie Li, Tingting Zou, Rong Wen, Yaqiong Hou, Huanlu Song, Hongliang Li, Hairan Ma, Jiao Shi

“…In this study, the aroma components of long shelf-life yoghurt produced from milk with varying acidity levels were identified using the Stir Bar Sorptive Extraction (SBSE) coupled with comprehensive two-dimensional gas chromatography−olfactometry−mass spectrometry technology (GC × GC-O-MS) for the first time. …”
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Analysis of oral cancer carcinogens in repeatedly heated cooking oils by Vidhant Krishna Nambiar, Vidya Mudliar, Inosi Salababa

“…The test group (T0-3) of oils were heated to 190 °C and tested for the presence of carcinogens using Gas chromatography Mass Spectroscopy after 1.5 h at recommended temperature (T0), reheated to 190 °C and tested after 1 h (T1), reheated to 190 °C and tested after 3 h (T2) and reheated to 190 °C and tested after 6 h (T3). …”
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Residual TPO Content of Photopolymerized Additively Manufactured Dental Occlusal Splint Materials by Philipp Messer-Hannemann, Max Wienhold, Hoda Esbak, Alexander Brunner, Andreas Schönebaum, Falk Schwendicke, Susanne Effenberger

“…TPO extraction was conducted using a maximum of eight extraction cycles of 72 h at a temperature of 37 °C until no more TPO eluates were detected by high-performance liquid chromatography (HPLC). The margin of safety (MoS) was calculated as the ratio between the Derived No-Effect Level (DNEL) and the estimated exposure based on the amount of TPO extracted. …”
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Standard operating procedure combined with comprehensive quality control system for multiple LC-MS platforms urinary proteomics by Xiang Liu, Haidan Sun, Xinhang Hou, Jiameng Sun, Min Tang, Yong-Biao Zhang, Yongqian Zhang, Wei Sun, Chao Liu, Urine Test Sample Working Group

“…At present, the comparability of urinary proteomics data across diverse liquid chromatography−mass spectrometry (LC-MS) platforms remains an area that requires investigation. …”
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Tear Film Proteome of Healthy Domestic Cats by Jéssica Fontes Veloso, Paula Elisa Brandão Guedes, Luciana Carvalho Lacerda, Juliano Oliveira Santana, Irma Yuliana Mora-Ocampo, Carlos Priminho Pirovani, Arianne Pontes Oriá, Alexandre Dias Munhoz, Renata Santiago Alberto Carlos

“…Schirmer tear test strips were used to collect tear samples of twelve healthy cats, which were mixed, centrifuged, and placed in a single 1.5 mL microtube that was frozen at −20°C, until analysis by two-dimensional polyacrylamide gel and mass spectrometry associated with high-performance liquid chromatography. The resulting spectra were analyzed and compared with the Swiss-Prot search tool. …”
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