Showing 121 - 140 results of 486 for search '"chromatin"', query time: 0.04s Refine Results
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  4. 124

    Integrative analysis of ATAC-seq and RNA-seq for cells infected by human T-cell leukemia virus type 1. by Azusa Tanaka, Yasuhiro Ishitsuka, Hiroki Ohta, Norihiro Takenouchi, Masanori Nakagawa, Ki-Ryang Koh, Chiho Onishi, Hiromitsu Tanaka, Akihiro Fujimoto, Jun-Ichirou Yasunaga, Masao Matsuoka

    Published 2025-01-01
    “…Compared to CD4+T cells from healthy donors, we found anomalous chromatin accessibility in HTLV-1infected CD4+ cells derived from ATL cases in terms of location and sample-to-sample fluctuations in open chromatin regions. …”
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    Article
  5. 125

    D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming by Fengchao Lang, Karambir Kaur, Haiqing Fu, Javeria Zaheer, Diego Luis Ribeiro, Mirit I. Aladjem, Chunzhang Yang

    Published 2025-02-01
    “…Mechanistically, D-2-HG diminishes the chromatin interactions in the DNA damage regions via revoking CTCF binding. …”
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    Article
  6. 126

    Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis by Kaiwen Sheng, Jun Chen, Ruitang Xu, Haoqiang Sun, Ran Liu, Yongjie Wang, Wenwen Xu, Jiao Guo, Miao Zhang, Shuai Liu, Juan Lei, Yawen Sun, Yang Jia, Dianhao Guo

    Published 2025-02-01
    “…Abstract Background Chromatin accessibility plays a crucial role in mediating transcriptional dysregulation and heterogeneity in Esophageal Squamous Cell Carcinoma (ESCC). …”
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    Article
  7. 127

    Generation and analysis of mouse embryonic stem cells with knockout of the <i>Mcph1</i> (microcephalin) gene by A. M. Yunusova, A. V. Smirnov, T. A. Shnaider, I. E. Pristyazhnuk, S. Y. Korableva, N. R. Battulin

    Published 2024-09-01
    “…Chromatin is not randomly distributed within the nucleus, but organized in a three-dimensional structure that plays a critical role in genome functions. …”
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    Article
  8. 128

    DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos by Grigorios Fanourgakis, Laura Gaspa-Toneu, Pavel A. Komarov, Panagiotis Papasaikas, Evgeniy A. Ozonov, Sebastien A. Smallwood, Antoine H. F. M. Peters

    Published 2025-01-01
    “…To assess the impact of altered sperm chromatin in formatting embryonic chromatin, we measure H3K4me3 occupancy at paternal and maternal alleles in 2-cell embryos using a transposon-based tagging approach. …”
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  9. 129
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    Peculiarities of the molecular composition of heterochromatin associated with pronucleoli in mouse embryos by I. O. Bogolyubova, Z. K. Sailau, D. S. Bogolyubov

    Published 2019-03-01
    “…Intriguingly, these zones contain not only tri-methylated histone Н3K9me3 as an epigenetic mark of repressed chromatin but also acetylated histone H4K5ac, a well-known marker of active chromatin. …”
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  11. 131

    Characterization of the Cannabis sativa glandular trichome epigenome by Lee J. Conneely, Bhavna Hurgobin, Sophia Ng, Muluneh Tamiru-Oli, Mathew G. Lewsey

    Published 2024-11-01
    “…The histone variant H2A.Z was largely found in intergenic regions and enriched in chromatin that contained genes involved in DNA homeostasis. …”
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  12. 132

    Cell Cycle Dynamics of the Nuclear Envelope by Roland Foisner

    Published 2003-01-01
    “…The inner membrane is linked to the lamina and chromatin by its integral membrane proteins, such as lamin B receptor (LBR), emerin, and various isoforms of lamina-associated polypeptides (LAP) 1 and 2, which bind lamins and/or chromatin. …”
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  13. 133

    DNA spontaneously wrapping around a histone core prefers negative supercoiling: A Brownian dynamics study. by Chunhong Long, Hongqiong Liang, Biao Wan

    Published 2025-01-01
    “…This advancement in understanding the spontaneous formation of nucleosomes may offer insights into the complex dynamics of chromatin assembly and the fundamental mechanisms governing the structure and function of chromatin.…”
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  14. 134

    Fetal-Perinatal Exposure to Bisphenol-A Affects Quality of Spermatozoa in Adulthood Mouse by Teresa Chioccarelli, Francesco Manfrevola, Marina Migliaccio, Lucia Altucci, Veronica Porreca, Silvia Fasano, Gilda Cobellis

    Published 2020-01-01
    “…In particular, BPA exposure interferes with biochemical mechanism useful to stabilize sperm chromatin condensation, as it interferes with oxidation of thiol groups associated to chromatin.…”
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  15. 135

    Nucleosome wrapping states encode principles of 3D genome organization by Zengqi Wen, Ruixin Fang, Ruxin Zhang, Xinqian Yu, Fanli Zhou, Haizhen Long

    Published 2025-01-01
    “…We discover that the chromatin of mouse ES cells forms Nucleosome Wrapping Domains (NRDs), which can also be observed in yeast and fly genomes. …”
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  16. 136

    Skewed Epigenetics: An Alternative Therapeutic Option for Diabetes Complications by Gabriele Togliatto, Patrizia Dentelli, Maria Felice Brizzi

    Published 2015-01-01
    “…A detailed investigation into epigenetic chromatin modifications in type 2 diabetes is underway. …”
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  17. 137

    Differential Dynamics of ATR-Mediated Checkpoint Regulators by Daniël O. Warmerdam, Roland Kanaar, Veronique A. J. Smits

    Published 2010-01-01
    “…Interestingly, ATRIP directly associated with locally induced UV damage, whereas Rad9 bound in a cooperative manner, which can be explained by the Rad17-dependent loading of Rad9 onto damaged chromatin. Although Chk1 dissociates from the chromatin upon UV damage, no change in the mobility of GFP-Chk1 was observed, supporting the notion that Chk1 is a highly dynamic protein.…”
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  18. 138

    Cytomictic Anomalous Male Meiosis and 2n Pollen Grain Formation in Mertensia echioides Benth. (Boraginaceae) from Kashmir Himalaya by Reyaz Ahmad Malik, Raghbir Chand Gupta, Santosh Kumari, Akhtar Hussain Malik

    Published 2014-01-01
    “…Whole chromatin transfer by the process of cytomixis could also have led to the formation of tetraploid cells. …”
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  19. 139

    Mms22-Rtt107 axis attenuates the DNA damage checkpoint and the stability of the Rad9 checkpoint mediator by Bingbing Wan, Danying Guan, Shibai Li, Tzippora Chwat-Edelstein, Xiaolan Zhao

    Published 2025-01-01
    “…Furthermore, Rtt107 binding to Mms22 helps to enrich the ubiquitin ligase complex on chromatin for targeting the chromatin-bound form of Rad9. …”
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  20. 140

    Identification of proteins that can participate in the recruitment of Ttk69 to genomic sites of Drosophila melanogaster by I. S. Osadchiy, T. N. Fedorova, P. G. Georgiev, O. G. Maksimenko

    Published 2019-03-01
    “…It can be assumed that Ttk69 represses some target genes by remodeling chromatin structure through the recruitment of the dNuRD complex. …”
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