Fetal-Perinatal Exposure to Bisphenol-A Affects Quality of Spermatozoa in Adulthood Mouse by Teresa Chioccarelli, Francesco Manfrevola, Marina Migliaccio, Lucia Altucci, Veronica Porreca, Silvia Fasano, Gilda Cobellis

“…In particular, BPA exposure interferes with biochemical mechanism useful to stabilize sperm chromatin condensation, as it interferes with oxidation of thiol groups associated to chromatin.…”
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Skewed Epigenetics: An Alternative Therapeutic Option for Diabetes Complications by Gabriele Togliatto, Patrizia Dentelli, Maria Felice Brizzi

“…A detailed investigation into epigenetic chromatin modifications in type 2 diabetes is underway. …”
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Differential Dynamics of ATR-Mediated Checkpoint Regulators by Daniël O. Warmerdam, Roland Kanaar, Veronique A. J. Smits

“…Interestingly, ATRIP directly associated with locally induced UV damage, whereas Rad9 bound in a cooperative manner, which can be explained by the Rad17-dependent loading of Rad9 onto damaged chromatin. Although Chk1 dissociates from the chromatin upon UV damage, no change in the mobility of GFP-Chk1 was observed, supporting the notion that Chk1 is a highly dynamic protein.…”
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Cytomictic Anomalous Male Meiosis and 2n Pollen Grain Formation in Mertensia echioides Benth. (Boraginaceae) from Kashmir Himalaya by Reyaz Ahmad Malik, Raghbir Chand Gupta, Santosh Kumari, Akhtar Hussain Malik

“…Whole chromatin transfer by the process of cytomixis could also have led to the formation of tetraploid cells. …”
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Identification of proteins that can participate in the recruitment of Ttk69 to genomic sites of Drosophila melanogaster by I. S. Osadchiy, T. N. Fedorova, P. G. Georgiev, O. G. Maksimenko

“…It can be assumed that Ttk69 represses some target genes by remodeling chromatin structure through the recruitment of the dNuRD complex. …”
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Valproic acid targets IDH1 mutants through alteration of lipid metabolism by Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum

“…Surprisingly, genes upregulated by VPA showed no enhanced chromatin accessibility at the promoter, but there was a correlation between VPA-downregulated genes and diminished promoter chromatin accessibility. …”
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Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

“…However, common experimental approaches used to study the local characteristics of chromatin have a number of technical limitations that may reduce the reliability of computational identification of genomic regulatory sequences. …”
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Functional properties of the Su(Hw) complex are determined by its regulatory environment and multiple interactions on the Su(Hw) protein platform by L. S. Melnikova, M. V. Kostyuchenko, V. V. Molodina, P. G. Georgiev, A. K. Golovnin

“…Some insulator complexes contribute to the higher-order organization of chromatin in topologically associated domains that are fundamental elements of the eukaryotic genomic structure. …”
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Diagnosis and Prognosis of Neuroendocrine Tumours of the Lung by Means of High Resolution Image Analysis by Uta Jütting, Peter Gais, Karsten Rodenacker, Joachim Böhm, Susanne Koch, Heinz W. Präuer, Heinz Höfler

“…The WDNEC cases are more similar in chromatin structure to TC than to SCLC. For the survival analysis, only chromatin features were selected to differentiate patients with better and worse prognosis independent of staging and tumour type.…”
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Chemical catalyst manipulating cancer epigenome and transcription by Yuki Yamanashi, Shinpei Takamaru, Atsushi Okabe, Satoshi Kaito, Yuto Azumaya, Yugo R. Kamimura, Kenzo Yamatsugu, Tomoya Kujirai, Hitoshi Kurumizaka, Atsushi Iwama, Atsushi Kaneda, Shigehiro A. Kawashima, Motomu Kanai

“…This H2BK120 acetylation-mediated removal of NELFE from chromatin reshapes transcription, slows leukemia cell viability, and reduces their tumorigenic potential in mice. …”
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Epigenetic Dynamics: Role of Epimarks and Underlying Machinery in Plants Exposed to Abiotic Stress by Manoj Kumar Dhar, Parivartan Vishal, Rahul Sharma, Sanjana Kaul

“…We provide examples of gene expression changes that are brought about by conversion of active chromatin to silent heterochromatin and vice versa. …”
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Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain by Dimitrios Tzachanis, Rajan Dewar, Katarina Luptakova, James D. Chang, Robin M. Joyce

“…The pericardial fluid contained a large number of highly atypical lymphocytes with moderate basophilic cytoplasm, rare punched-out vacuoles, a vesicular nuclear chromatin, large nucleolus, and marginated chromatin that by FISH were positive for the 8;14 translocation. …”
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Nutrigenomic regulation of sensory plasticity by Hayeon Sung, Anoumid Vaziri, Daniel Wilinski, Riley KR Woerner, Lydia Freddolino, Monica Dus

“…Here, we show that the metabolic enzyme O-GlcNAc Transferase (OGT) moonlights on the chromatin of the D. melanogaster gustatory neurons to instruct changes in chromatin accessibility and transcription that underlie sensory adaptations to a high-sugar diet. …”
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Epigenetics and Shared Molecular Processes in the Regeneration of Complex Structures by Labib Rouhana, Junichi Tasaki

“…This review provides an overview of known contributions to regenerative processes by noncoding RNAs and chromatin-modifying enzymes involved in epigenetic regulation.…”
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Epigenetic Modifications and Potential New Treatment Targets in Diabetic Retinopathy by Lorena Perrone, Carmela Matrone, Lalit P. Singh

“…Recent studies also underline the role of epigenetic chromatin modifications as mediators of the metabolic memory. …”
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Epigenetic Application of ATAC-Seq Based on Tn5 Transposase Purification Technology by Wangchun Li, U Tim Wu, Yu Cheng, Yanhao Huang, Lipeng Mao, Menghan Sun, Congling Qiu, Lin Zhou, Lijuan Gao

“…Assays of transposase accessible chromatin sequencing (ATAC-seq) is an efficient assay to investigate chromatin accessibility, which depends on the activity of a robust Tn5 transposase to fragment the genome while cutting in the sequencing adapters. …”
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SMC translocation is unaffected by an excess of nucleoid associated proteins in vivo by Zhongqing Ren, Lindsey E. Way, Xindan Wang

“…By fluorescence microscopy and chromatin immunoprecipitation, we observed that these proteins bound to the genome in characteristic manners. …”
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Oxidative Stress and DNA Methylation in Prostate Cancer by Krishna Vanaja Donkena, Charles Y. F. Young, Donald J. Tindall

“…DNA methylation is perhaps the most extensively studied epigenetic modification, which plays an important role in the regulation of gene expression and chromatin architecture, in association with histone modification and other chromatin-associated proteins. …”
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The role of highly dispersed silica nanoparticles in the realization of the effects of granulosa on the maturation and fertilization competence of <i>Sus scrofa domesticus</i> oocy... by T. I. Kuzmina, I. V. Chistyakova, A. O. Prituzhalova, D. N. Tatarskaya

“…Analysis of the oocyte chromatin status by the Tarkowsky method and assessment of the level of destructive changes in chromatin (apoptosis, pyknosis) revealed a significant percentage increase in matured oocytes and a decrease in the proportion of granulosa cells with degenerated chromatin when using the original culture system. …”
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Two Sides of the Same Coin: TFIIH Complexes in Transcription and DNA Repair by Alexander Zhovmer, Valentyn Oksenych, Frédéric Coin

“…Recently, a new technique combining chromatin immunoprecipitation and western blotting resolved the hidden nature of the TFIIH complex participating in DNA repair. …”
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