Showing 241 - 260 results of 486 for search '"chromatin"', query time: 0.05s Refine Results
  1. 241

    The Emerging Functions of Long Noncoding RNA in Immune Cells: Autoimmune Diseases by Keshav Raj Sigdel, Ao Cheng, Yin Wang, Lihua Duan, YanLin Zhang

    Published 2015-01-01
    “…The lncRNAs are emerging as an important regulator of biological process, such as chromatin remodeling, gene transcription, protein transport, and trafficking through diverse mechanisms. …”
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    Article
  2. 242

    Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells by Ying Yin, Liquan Zhou, Shuiqiao Yuan

    Published 2018-01-01
    “…Some other retrotransposons reside in the vicinity of endogenous genes and are capable of regulating nearby genes and cell fate, possibly through providing alternative promoters, regulatory modules, or orchestrating high-order chromatin assembly. In addition, retrotransposons may mediate epigenetic memory, regulate gene expression posttranscriptionally, defend virus infection, and so on. …”
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  3. 243

    A chromosome-level genome assembly of wild silkmoth, Bombyx mandarina by Jung Lee, Takashi Kiuchi, Katsushi Yamaguchi, Shuji Shigenobu, Atsushi Toyoda, Toru Shimada

    Published 2025-01-01
    “…., transcriptome-based gene prediction, Assay for Transposase-Accessible Chromatin (ATAC)-seq, and PIWI-interacting RNA (piRNA)-targeted small RNA-seq. …”
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    Article
  4. 244

    The role of epigenetics in plant pathogens interactions under the changing environments: A systematic review by Wenhao Wu, Guoqiang Fan

    Published 2025-03-01
    “…DNA methylation influences plant immunity by modulating gene expression and chromatin accessibility, while histone modifications, such as acetylation and methylation, enable plants to establish robust defenses by fine-tuning stress-responsive genes. …”
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    Article
  5. 245

    Molecular architecture of the altered cortical complexity in autism by Makliya Mamat, Yiyong Chen, Wenwen Shen, Lin Li

    Published 2025-01-01
    “…Partial least squares regression analysis revealed gene sets associated with these cortical complexity changes, enriched for biological functions related to synaptic transmission, synaptic plasticity, mitochondrial dysfunction, and chromatin organization. Cell-specific analyses, protein–protein interaction network analysis and gene temporal expression profiling further elucidated the dynamic molecular landscape associated with these alterations. …”
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  6. 246

    Burkitt Lymphoma Presenting as Unilateral Deafness in an Immunocompetent Patient by Andre Pinto, Offiong Francis Ikpatt, Jennifer Chapman-Fredericks

    Published 2012-01-01
    “…Examination of the peripheral smear demonstrated the presence of increased circulating blast-like cells of intermediate size, with basophilic cytoplasm and nuclei with open chromatin. MRI of the brain was compatible with hemorrhagic labyrinthitis. …”
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  7. 247

    Regulatory roles of RNA binding proteins in the Hippo pathway by Shuchang Peng, Chenglin Li, Yanwen He, Lei Xue, Xiaowei Guo

    Published 2025-01-01
    “…It also explores the dynamic interplay between RBPs, non-coding RNAs, TFs, and DNA on chromatin. Additionally, it also outlines future perspectives, including the essential non-canonical functions of RBPs and emerging roles of non-canonical RBPs as transcription factors (TFs) in genes transcription. …”
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  8. 248

    Gastric Endocrine Cell Carcinoma Coexistent with Adenocarcinoma by Nobuhiro Takeuchi, Nomura Yusuke, Tetsuo Maeda, Kazuyoshi Naba

    Published 2013-01-01
    “…Several biopsied specimens revealed proliferation of small and heterogeneous cancer cells with rich chromatin and fibrous septum with rich vessels at connective tissues, which was confirmed as gastric endocrine cell carcinoma (ECC) on immunostaining with chromogranin and synaptophysin. …”
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    Article
  9. 249

    GATA2 participates in protection against hypoxia-induced pulmonary vascular remodeling. by Yuko Shirota, Shin'ya Ohmori, James Douglas Engel, Takashi Moriguchi

    Published 2024-01-01
    “…Transcript analysis and chromatin immunoprecipitation assays using mouse pulmonary vascular endothelial cells revealed that GATA2 directly regulates the expression of G6pdx (a crucial cytoprotective enzyme) and Bmp4 (a growth factor that mediates vascular homeostasis). …”
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    Article
  10. 250

    Dietary, Metabolic, and Potentially Environmental Modulation of the Lysine Acetylation Machinery by Go-Woon Kim, Goran Gocevski, Chao-Jung Wu, Xiang-Jiao Yang

    Published 2010-01-01
    “…As a major posttranslational modification, lysine (K) acetylation has received much attention, owing largely to its significant effects on chromatin dynamics and other cellular processes across species. …”
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  11. 251

    Transformation of brain myeloid cell populations by SIV in rhesus macaques revealed by multiomics by Xiaoke Xu, Meng Niu, Benjamin G. Lamberty, Katy Emanuel, Moses Jedd Facun Apostol, Howard S. Fox

    Published 2025-01-01
    “…A unique population of microglia-like cells is found in which the chromatin accessibility of genes diverges from their RNA expression. …”
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  12. 252

    Angioleiomyoma of the uterus presenting as an endometrial polyp: An uncommon occurrence of two cases with a literature review by Vamsi K. Kapaganti, Mohammed Shahin, Anurag Mishra, Pruthiviraj Sethi, Saubhagya K. Jena, Bhismadev Chhatria, Pavithra Ayyanar

    Published 2024-12-01
    “…These spindle cells have oval and cigar-shaped nuclei, fine chromatin, and a moderate amount of eosinophilic cytoplasm, resembling smooth muscle cells. …”
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  13. 253

    Phosphorylation of a nuclear condensate regulates cohesion and mRNA retention by Alexa B. R. McIntyre, Adrian Beat Tschan, Katrina Meyer, Severin Walser, Arpan Kumar Rai, Keisuke Fujita, Lucas Pelkmans

    Published 2025-01-01
    “…We find that many transcripts are preferentially enriched within nuclear speckles compared to the nucleoplasm, particularly chromatin- and nucleus-associated transcripts. While total polyadenylated RNA retention increases with nuclear speckle cohesion, the ratios of most mRNA species to each other are constant, indicating non-selective retention. …”
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  14. 254

    Homo Sapiens Chromosomal Location Ontology: A Framework for Genomic Data in Biomedical Knowledge Graphs by Taha Mohseni Ahooyi, Benjamin Stear, J. Alan Simmons, Christopher M. Nemarich, Jonathan C. Silverstein, Deanne M. Taylor

    Published 2025-01-01
    “…The utility and performance of HSCLO are demonstrated through a case study involving the integration of high-resolution chromatin interaction data, which reveals significant improvements in query efficiency and data linkage. …”
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  15. 255

    H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy by Monika Podhorecka, Andrzej Skladanowski, Przemyslaw Bozko

    Published 2010-01-01
    “…Phosphorylation of H2AX plays a key role in DDR and is required for the assembly of DNA repair proteins at the sites containing damaged chromatin as well as for activation of checkpoints proteins which arrest the cell cycle progression. …”
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  16. 256

    Tumor-initiating and metastasis-initiating cells of clear-cell renal cell carcinoma by Dinh-Xuan Pham, Tien Hsu

    Published 2025-02-01
    “…TICs likely originate from kidney tubule progenitor cells bearing VHL gene inactivation, including chromatin 3p loss. Recent studies also point to the importance of microenvironment reconstituted by the VHL-deficient kidney tubule cells in promoting ccRCC initiation and progression. …”
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  17. 257

    Interplay between Epigenetics and Genetics in Cancer by Jae Duk Choi, Jong-Soo Lee

    Published 2013-12-01
    “…Genomic instability, which occurs through both genetic mechanisms (underlying inheritable phenotypic variations caused by DNA sequence-dependent alterations, such as mutation, deletion, insertion, inversion, translocation, and chromosomal aneuploidy) and epigenomic aberrations (underlying inheritable phenotypic variations caused by DNA sequence-independent alterations caused by a change of chromatin structure, such as DNA methylation and histone modifications), is known to promote tumorigenesis and tumor progression. …”
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  18. 258

    The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation. by Sundeep Kalantry, Terry Magnuson

    Published 2006-05-01
    “…The Polycomb group (PcG) proteins are thought to silence gene expression by modifying chromatin. The Polycomb repressive complex 2 (PRC2) plays an essential role in mammalian X-chromosome inactivation (XCI), a model system to investigate heritable gene silencing. …”
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  19. 259

    FXR Mediates Adenylyl Cyclase 8 Expression in Pancreatic β-Cells by Xiangchen Kong, Bingfeng Li, Yushen Deng, Xiaosong Ma

    Published 2019-01-01
    “…Thus, this study indicates that FXR is a critical transcription factor that mediates ADCY8 expression in pancreatic β-cells and has characterized the chromatin modification associated with Adcy8 transcription.…”
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  20. 260

    Cytomorphological traits of fine-needle aspirates of hyalinizing trabecular tumor of the thyroid gland: A brief report by Fei Wang, Yufei Liu

    Published 2023-07-01
    “…The tumor cells exhibited ovoid nuclei, abundant cytoplasm, fine chromatin, nuclear crowding and overlapping, and small nucleoli. …”
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    Article