-
181
Igf2/H19 Imprinting Control Region (ICR): An Insulator or a Position-Dependent Silencer?
Published 2001-01-01“…This repression of maternal Igf2 has recently been postulated to be due to a chromatin boundary or insulator function of the unmethylated ICR. …”
Get full text
Article -
182
<i>Triticum durum</i> Desf. is a valuable source for spring bread wheat genetic diversity enhancement
Published 2023-10-01“…Enhancement of the Triticum aestivum L. genetic diversity by means of alien chromatin, including that from Triticum durum Desf., is an important element in the breeding of bread wheat cultivars that meet modern requirements.Materials and methods. …”
Get full text
Article -
183
Role of sirtuins in epigenetic regulation and aging control
Published 2024-04-01“…In addition to a brief description of the main SIRT enzymatic and biological activity, the review discusses its role in the epigenetic regulation of chromatin structure, including the context of the development of genome instability associated with aging. …”
Get full text
Article -
184
神经母细胞瘤的染色体改变
Published 1982-01-01“…Cox等(1965)发现神经母细胞瘤患者肿瘤细胞中出现一种成对排列的微小染色体——双微小染色体(Minute chromatin bcdies)。Sandberg等也在1例神经母细胞瘤…”
Get full text
Article -
185
Coordinated neuron-specific splicing events restrict nucleosome engagement of the LSD1 histone demethylase complex
Published 2025-01-01“…Summary: Chromatin regulatory proteins are expressed broadly and assumed to exert the same intrinsic function across cell types. …”
Get full text
Article -
186
-
187
Comprehensive Analysis of Transcriptome Sequencing Data in the Lung Tissues of COPD Subjects
Published 2015-01-01“…Oxidative phosphorylation, protein degradation, and chromatin modification were the most dysregulated pathways in the lung tissues of COPD subjects. …”
Get full text
Article -
188
Structural insights into how Cas9 targets nucleosomes
Published 2024-12-01“…The eukaryotes, the target of genome editing, store their genome DNA in chromatin, in which the nucleosome is a basic unit. …”
Get full text
Article -
189
Nesprin-2 Interacts with Condensin Component SMC2
Published 2017-01-01“…We analyze here the function of Nesprin-2 in chromatin interactions in interphase and dividing cells. …”
Get full text
Article -
190
Influence of human peripheral blood samples preprocessing on the quality of Hi-C libraries
Published 2023-03-01“…The genome-wide variant of the chromatin conformation capture technique (Hi-C) is a powerful tool for revealing patterns of genome spatial organization, as well as for understanding the effects of their disturbance on disease development. …”
Get full text
Article -
191
Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis
Published 2025-02-01“…ATAC-seq analysis revealed that glycolysis in BC cells enhanced chromatin accessibility. Additionally, we confirmed that HDAC2 and HDAC3 act as “erasers” for H3 lysine lactylation. …”
Get full text
Article -
192
Hairy transcriptional repression targets and cofactor recruitment in Drosophila.
Published 2004-07-01“…The majority of Hairy targets are associated with the presence of a combination of dCtBP and dSir2. Thus, the DamID chromatin profiling technique provides a systematic means of identifying transcriptional target genes and of obtaining a global view of cofactor recruitment requirements during development.…”
Get full text
Article -
193
Evaluation of developmental competence of Sus scrofa domesticus (L.) oocyte-cumulus complexes after intra- and extraovarian vitrification
Published 2021-10-01“…The aim of the present study was to identify the influence of extra- (EOV) and intraovarian vitrification (IOV) on mitochondrial activity (MA) and chromatin state in porcine oocytes during maturation in vitro. …”
Get full text
Article -
194
Insights Into the Role of Bmi‐1 Deregulation in Promoting Stemness and Therapy Resistance in Glioblastoma: A Narrative Review
Published 2025-01-01“…We find that Bmi‐1 participates in regulating the gene expression and chromatin structure of several tumor suppressor genes or cell cycle inhibitors. …”
Get full text
Article -
195
Aortic body tumor in a kangal dog
Get full text
Article -
196
Ejaculate Oxidative Stress Is Related with Sperm DNA Fragmentation and Round Cells
Published 2015-01-01“…Oxidative stress levels from N1 (low) to N4 (high) were assessed in ejaculates using oxiSperm; DFI (sperm DNA fragmentation index) as assessed by the SCSA (Sperm Chromatin Structure Assay) was used for evaluation of sperm chromatin integrity. …”
Get full text
Article -
197
A 16-Day-Old Infant with a Clinical Diagnosis of Classical Cornelia de Lange Syndrome
Published 2020-01-01“…It is caused by genetic variations in the chromatin regulator genes, most commonly, the cohesin complex. …”
Get full text
Article -
198
THE ORIGIN OF SYNAPTONEMAL COMPLEX PROTEINS. SEARCH FOR RELATED PROTEINS IN PROTEOMES OF ALGAE, LOWER FUNGI, MOSSES, AND PROTOZOANS
Published 2014-12-01“…This domain recognizes the chromatin state and recruits other proteins for SC formation.…”
Get full text
Article -
199
The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic Landscape
Published 2016-01-01“…Epigenetic mechanisms regulate chromatin state and gene transcription without any change in DNA sequence, resulting in the alteration of phenotypes in several cell types, especially RASFs. …”
Get full text
Article -
200
DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells
Published 2024-12-01“…Abstract Pluripotent stem cells possess a unique nuclear architecture characterized by a larger nucleus and more open chromatin, which underpins their ability to self-renew and differentiate. …”
Get full text
Article