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1121
Glomerulopathy in the KK.Cg-Ay/J Mouse Reflects the Pathology of Diabetic Nephropathy
Published 2013-01-01“…Compared to KK- controls, 26-week-old KK- mice had elevated HbA1c, insulin, leptin, triglycerides, and cholesterol, and Unx further elevated these markers of metabolic dysregulation. …”
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1122
A more accurate relationship between serum androgen and metabolism among healthy, nonobese, reproductive-age women based on liquid chromatography-tandem mass spectrometry
Published 2024-01-01“…High-density lipoprotein (HDL), low-density lipoprotein, triglycerides, and total cholesterol were used as lipid markers. Fasting blood glucose (FBG), fasting insulin, and the homeostatic model assessment of insulin resistance were used to assess insulin resistance and glucose metabolism. …”
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1123
Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India
Published 2025-02-01“…Obese level BMI (AOR 4.17; 95% CI 3.59–4.84), High cholesterol (AOR 1.51; 95% CI 1.22–1.87), History of heart disease and stroke (AOR 1.85; 95% CI 1.60–2.13), and males (AOR 1.25; 95% CI 1.16–1.34) had positive odds for high risk of diabetes. …”
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1124
Nutritional content and healthiness in sweet and salty snacks and beverages popular in South Korea and the United States assessed by nutrition labels: a cross-sectional comparative...
Published 2024-12-01“…Results Overall, Korean snacks contained significantly more protein, total fat, saturated fat, and cholesterol than US snacks. However, the US chips and carbonated drinks contained more sodium, while the US energy drinks contained more caffeine than Korean products. …”
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1125
Integrated analysis of genetic, proteinic, and metabolomic alterations in Behcet’s disease
Published 2025-01-01“…In this study, the results of binomial analysis showed that the circulating levels of 38 molecules, including interferon-γ and interleukin 17, were consistently upregulated, whereas high density lipoprotein cholesterol, apolipoprotein A, hemoglobin, and glutathione were consistently downregulated. …”
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1126
Status of sleeping habits and its influence on growth and metabolism of children in Beijing: a population-based cross-sectional study
Published 2025-02-01“…SDB was significantly associated with BMI, fat mass percentage (FMP), waist-to-height ratio (WHtR), SBP, triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) across all age groups (p < 0.05), while SDB was positively correlated with HAZ only in children aged 6–11 years (β = 0.240, p < 0.05). …”
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1127
Cardiometabolic index as a predictor of gallstone incidence in U.S. adults: insights from NHANES 2017–2020
Published 2025-01-01“…The GSD group included more females and older adults, with increased risks for hypertension, diabetes, higher serum cholesterol and creatinine levels, and a higher risk of cancer. …”
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1128
Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies
Published 2025-01-01“…Abstract Background Atherogenic index of plasma (AIP), a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol concentrations, is associated with the burden of atherosclerosis. …”
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1129
Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma
Published 2025-01-01“…We show in a lymphangiogenic murine melanoma that lymphatic endothelial cells (LECs) upregulate the enzyme Ch25h, which catalyzes the formation of 25-hydroxycholesterol (25-HC) from cholesterol and plays important roles in lipid metabolism, gene regulation, and immune activation. …”
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1130
mHealth Intervention for Dementia Prevention through lifestyle Optimisation (MIND-PRO) in a primary care setting: protocol for a randomised controlled trial in people with low SES...
Published 2025-02-01“…The primary effectiveness outcome is a composite score of systolic blood pressure, non-high-density lipoprotein cholesterol and body mass index. Implementation outcomes include coverage, adoption, acceptability, appropriateness, feasibility, fidelity, costs and sustainability of the intervention. …”
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1131
Meta-Analysis of the Effect of Resistance Exercise Prescription on Glucose and Lipid Metabolism in Overweight and Obese Adults
Published 2024-11-01“…The literature was screened by 2 researchers according to inclusion and exclusion criteria and relevant data were extracted.Meta-analysis of included literature was performed using RevMan 5.3 software, and publication bias was assessed using funnel plots.ResultsA total of 17 papers and 700 study subjects were included, with 351 cases in the test group, and 349 cases in the control group.Meta-analysis results showed that compared with the control group, the glycosylated hemoglobin of the test group with resistance exercise[SMD (95% CI) =-0.30(-0.53--0.07), P=0.010], fasting blood glucose[SMD (95% CI)=-0.58(-0.90--0.26), P < 0.001], insulin resistance index[SMD (95% CI) =-0.90 (-1.42--0.38), P < 0.001], and low-density lipoprotein cholesterol (LDL-C)[SMD (95% CI) =-0.28 (-0.53--0.04), P=0.020] levels were reduced.Subgroup analysis showed that the glucose metabolism levels of the test group with only resistance exercise and a combination of resistance-anaerobic exercise were significantly lower than those of the control group(both P < 0.05).The heterogeneity of the effect of resistance exercise on glucose metabolism in Asian populations(I2=57%) was smaller than that in Caucasion(I2=76%) and other populations(I2=94%), and the level of decrease in glucose metabolism indexes was significant[SMD(95% CI)=-1.15(-1.73--0.57), P < 0.001].ConclusionResistance exercise can significantly reduce the level of glycolipid metabolism indexes in overweight or obese people.…”
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1132
En Balance: The Contribution of Physical Activity to the Efficacy of Spanish Diabetes Education of Hispanic Americans with Type 2 Diabetes
Published 2020-01-01“…We found that the subjects in the active group with decreased kynurenine concentrations displayed statistically greater improvements in fasting blood glucose, A1C, cholesterol, and triglycerides despite weight loss being higher in the group with increased kynurenine concentrations. …”
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1133
Structured follow-up pathway to support people after transient ischaemic attack and minor stroke (SUPPORT TIA): protocol for a feasibility study and process evaluation
Published 2022-06-01“…The clinic appointment will collect body mass index, blood pressure, cholesterol and medication. Assessment of feasibility and acceptability will include quantitative process variables (such as recruitment and questionnaire response rates), structured observations of study processes, and interviews with a subsample of participants and clinical staff.Ethics and dissemination Favourable ethical opinion was gained from the Wales Research Ethics Committee (REC) 1 (23 February 2021, REC reference: 21/WA/0036). …”
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1134
Exploring the comorbidity mechanisms between atherosclerosis and hashimoto’s thyroiditis based on microarray and single-cell sequencing analysis
Published 2025-01-01“…Abstract Atherosclerosis (AS) is a chronic vascular disease characterized by inflammation of the arterial wall and the formation of cholesterol plaques. Hashimoto’s thyroiditis (HT) is an autoimmune disorder marked by chronic inflammation and destruction of thyroid tissue. …”
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1135
Development and internal validation of the Edmonton Obesity Staging System-2 Risk screening Tool (EOSS-2 Risk Tool) for weight-related health complications: a case-control study in...
Published 2022-06-01“…Of 14 candidate risk factors, 6 (family history of diabetes, hypertension, high sugar in blood/urine, high cholesterol and self-reported bodily pain and disability) were automatically included based on definitional or obvious correlational criteria. …”
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1136
Dietary omega-3 fatty acids affect the growth performance of broiler chickens reared at high stocking density
Published 2025-01-01“…The serum concentration of cholesterol in broilers with high SD fed diets high in omega-3 fatty acids was lower than broilers with high SD fed diets low in omega-3 fatty acids (P < 0.05). …”
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1137
Allium cepa L. as a natural antioxidant: Its efficacy in combating heat stress-induced physiological alterations
Published 2025-03-01“…However, there was a significant rise in the levels of inflammatory markers, platelet counts, LDL-c triglyceride (TG), total cholesterol (TC), and white blood cell (WBC). Many of these alterations were reversed by AC supplementation, by increasing RBC counts, HB levels, and antioxidant enzyme activities while decreasing LDL-c, TG and TC, MDA, and TNF-α (tumor necrosis factor-α). …”
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1138
Lipidomics-based association study reveals genomic signatures of anti-cancer qualities of pigmented rice sprouts
Published 2025-01-01“…This superior MTA combination exhibited potent inhibitory activity against HCT116 and A549 cell lines, with average 1/IC50 values of 0.03 and 0.02 (mL/μg), respectively, compared to the inferior MTAs.DiscussionCollectively, our findings demonstrate that MTAs linked to selected GDSL esterase/lipase (GELP) genes, OsACP1, and lecithin-cholesterol acyltransferase significantly enhance antioxidant and anti-cancer properties, potentially through the mobilization of unsaturated lipids and carotenoids during germination. …”
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1139
Blood metabolomic profile in patients with type 2 diabetes mellitus with diabetic peripheral neuropathic pain
Published 2025-02-01“…DPNP patients showed elevated fasting blood glucose, glutamate, PC aa C36:1, lysoPC a C18:1, and lysoPC a C18:2, while low‐density lipoprotein cholesterol, phenylalanine, and tryptophan were reduced. …”
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1140
Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function
Published 2025-01-01“…While follicle-stimulating hormone and luteinizing hormone levels were not significantly affected, Vitamin D levels were higher in the well-controlled group (P = 0.0002), suggesting a potential role for Vitamin D in ED, although further investigation is needed. Cholesterol, low-density lipoprotein, high-density lipoprotein, triglycerides, PSA, thyroid-stimulating hormone, and T4 levels did not show significant differences but might warrant further exploration. …”
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