15-Lipoxygenase-1 Is Involved in the Effects of Atorvastatin on Endothelial Dysfunction by Peng Zhang, Xin Xing, Chunxiao Hu, Hui Yu, Qian Dong, Guanglei Chang, Shu Qin, Jian Liu, Dongying Zhang

“…Statins exert pleiotropic effects on endothelial cells in addition to lowering cholesterol. 15-Lipoxygenase-1 (ALOX15) has been implicated in vascular inflammation and disease. …”
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Moderate-Intensity Exercise and Musical Co-Treatment Decreased the Circulating Level of Betatrophin by Hendra Susanto, Ahmad Taufiq, Sugiharto, Desiana Merawati, Khumaira Marsyidah Badu, Jerry Dwi Trijoyo Purnomo, Adeodatus Yuda Handaya

“…By contrast, the plasma level of betatrophin was negatively associated with age (r = −0.298, p≤0.05) and LDL cholesterol (r = −0.372, p≤0.05). Importantly, betatrophin is a significant predictor for energy expenditure (p≤0.001) and plasma triglyceride levels (p≤0.05). …”
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Optimal calorie restriction threshold: effect of FATmax exercise combined with different proportions of calorie restriction on hypercholesterolemia by Yuetong Wu, Li Zhang, Jing Li, Boyang Xue, Wenyuan Shang, Yingli Lu

“…FATmax exercises were conducted 5 times per week, lasting 1 h each.Results1) Compared with baseline, subjects’ body weight, fat mass and body fat rate decreased significantly; fat-free mass also decreased significantly in the REE, REE + PA33%, and REE + PA67% groups. 2) Subjects’ serum TC decreased significantly; serum LDL-C and ApoB decreased significantly in the REE, REE + PA33%, and REE + PA67% groups; there were no significant changes in serum HDL-C and ApoA1. 3) Serum PCSK9 was significantly decreased in the REE and the REE + PA 67% groups; serum LDLR was significantly decreased in all groups of subjects. 4) Between the groups, the rate of change in serum LDL-C was significantly different.ConclusionFATmax exercise combined with proper proportions of calorie restriction can significantly decrease serum cholesterol levels and fat mass in hypercholesterolemic patients. …”
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Contribution of individual phospholipase A2 enzymes to the cleavage of oxidized phospholipids in human blood plasma by Philipp Jokesch, Olga Oskolkova, Maria Fedorova, Bernd Gesslbauer, Valery Bochkov

“…Human plasma contains both genuine phospholipases A2 [platelet activating factor acetyl hydrolase (PAF-AH) (also called Lp-PLA2) and secretory phospholipase A2] and multifunctional enzymes capable of removing sn-2 residues in native and oxidized PLs (lecithin-cholesterol acyltransferase, peroxiredoxin-6). The goal of this study was to compare relative activities of different PLA2 enzymes by analyzing cleavage of oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-phosphatidylcholine (OxPAPC) and oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-phosphatidylethanolamine (OxPAPE) by diluted plasma in the presence of enzyme inhibitors. …”
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Non-support from the immediate boss is associated with stress and unsafety at work by Fredrik Iredahl, Elvar Theodorsson, Mike Jones, Tomas Faresjö, Åshild Faresjö

“…The risk for hypertension and high cholesterol was increased by 28 %, respectively, 13 % being in the non-support group. …”
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High Blood Pressure Effects on the Blood to Cerebrospinal Fluid Barrier and Cerebrospinal Fluid Protein Composition: A Two-Dimensional Electrophoresis Study in Spontaneously Hypert... by Ibrahim González-Marrero, Leandro Castañeyra-Ruiz, Juan M. González-Toledo, Agustín Castañeyra-Ruiz, Hector de Paz-Carmona, Rafael Castro, Juan R. Hernandez-Fernaud, Agustín Castañeyra-Perdomo, Emilia M. Carmona-Calero

“…The aim of the present work is to analyze the cerebrospinal fluid proteomic profile, trying to find possible biomarkers of the effects of hypertension of the blood to CSF barrier disruption in the brain and their participation in the cholesterol and β-amyloid metabolism and inflammatory processes. …”
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Gut microbial subtypes and clinicopathological value for colorectal cancer by Shuwen Han, Jing Zhuang, Yifei Song, Xinyue Wu, Xiaojian Yu, Ye Tao, Jian Chu, Zhanbo Qu, Yinhang Wu, Shugao Han, Xi Yang

“…., free fatty acids and total cholesterol) and CRC pathological information (e.g., tumor depth) varied among gut microbial subtypes. …”
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Achillea millefolium capsule improved liver enzymes and lipid profile compared to placebo in patients with type 2 diabetes: a double-blind randomized clinical trial by Shole Daneshvar-Ghahfarokhi, Hassan Ahmadinia, Tabandeh Sadeghi, Elham Basirat, Vahid Mohammadi-Shahrokhi

“…A significant reduction in the levels of serum lipids such as triglyceride (TG; from 161.7 ± 77.18 to 147.3 ± 66.79, p = 0.045), low-density lipoprotein (LDL; from 98.90 ± 35.67 to 80.86 ± 32.10, p = 0.001), and total cholesterol (TC; from 168.3 ± 47.46 to 150.1 ± 38.77, p = 0.006) was noted in AM group. …”
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3β-Hydroxysteroid-Δ24 Reductase (DHCR24) Protects Pancreatic β Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Speci... by Yang Li, Xude Wang, Baoyu Yang, Haozhen Wang, Zhenzhong Ma, Ziyin Lu, Xiuli Lu, Bing Gao

“…DHCR24 overexpression also inhibited the generation of intracellular reactive oxygen species (ROS) induced by ER stress and protected cells from apoptosis caused by treatment with both cholesterol and hydrogen peroxide. In summary, these data demonstrate, for the first time, that DHCR24 protects pancreatic β cells from apoptosis induced by ER stress.…”
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Impact of Different Metabolic Indicators on Ventricular Repolarization Indices in Obese Children: A Case Control Study by Asmaa A El Sehmawy, Rasha Abd El Samad Fawaz, Nadia Ahmed Agiba, Eman Aziz Elsherbiny, Nglaa Fathi Agaba, Doaa Sayed Mohammed, Haidy Mahmoud Nasr, Fatma Elzhraa AE Diab, Amal M Ahmed, Shorouk Issa Mahfouz, Heba T Okda, Doaa Sadek Ahmed

“…Results: Obese children had significantly higher serum levels of triglycerides, cholesterol, LDL, fasting insulin, and HOMA-IR compared to controls. …”
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Nutritional Status and Cardiovascular Health in Female Adolescent Elite-Level Artistic Gymnasts and Swimmers: A Cross-Sectional Study of 31 Athletes by Boštjan Jakše, Barbara Jakše, Nataša Fidler Mis, Borut Jug, Dorica Šajber, Uroš Godnov, Ivan Čuk

“…Gymnasts had higher LDL cholesterol (2.7 vs. 2.2 mmol/L, p<0.011), and swimmers had higher systolic BP (126 vs. 107 mmHg, p<0.001). …”
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Advanced Copper Oxide Chemical and Green Synthesis: Characterization and Antibacterial Evaluation by Ecaterina Magdalena Modan, Adriana-Gabriela Schiopu, Sorin Georgian Moga, Denis Aurelian Negrea, Daniela Istrate, Ion Ciuca, Mihai Oproescu

“…This study investigated two synthesis methods for structured CuO: microwave-assisted hydrolysis and ultrasound using copper acetate and KOH, and an eco-friendly method involving cholesterol-free egg white albumin and <i>Solanum lycopersicum</i> extract. …”
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Immune system effectors as biomarkers of prognosis after acute burns in a case-control study by Alejandro Ferrari, Lorena Di Croce, Sabrina Saavedra, Marisel Hartwig, Omar Perrone, María Alejandra Guzmán

“…Laboratory determinations were immunoglobulin G (IgG), immunoglobulin M (IgM), C-reactive protein (CRP), complement C4 protein (C4), total serum protein (TP), albumin, prealbumin, cholesterol (CHOL), pseudocholinesterase activity (CHE), and transferrin. …”
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Physiological Properties of Dietary Ellagitannin-Rich Preparations Obtained from Strawberry Pomace Using Different Extraction Methods by Juśkiewicz Jerzy, Król Bogusław, Kosmala Monika, Milala Joanna, Zduńczyk Zenon, Żary-Sikorska Ewa

“…The preparations were applied in cholesterol-containing diets that had equal content of ellagitannins (0.03%). …”
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Optimization of the Solid-state Fermentation Process for Morchella esculenta Fermented Wheat and Analysis of Its Nutritional Components, Physicochemical Properties and Antioxidant... by Dandan GU, Xue DONG, Jinxiu ZHANG, Xiaoru WANG, Zongshuo ZHAO, Li'an WANG

“…Under simulated conditions of the human stomach and intestine, the cholesterol adsorption rate increased by 86.29% and 290.14%, respectively. …”
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Risk Factors for Cognitive Impairment in Patients with Type 2 Diabetes by Lin Sun, Xue Diao, Xiaokun Gang, You Lv, Xue Zhao, Shuo Yang, Ying Gao, Guixia Wang

“…Age, educational level, duration of diabetes, fasting blood glucose (FBG), HbA1c, total cholesterol (TC), triglyceride (TG), and 24-hour urine protein were significantly associated with cognitive impairment in T2DM patients of advanced age. …”
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Serum Fibroblast Growth Factor 21 Levels Are Correlated with the Severity of Diabetic Retinopathy by Yuan Lin, Ye-cheng Xiao, Hong Zhu, Qing-yan Xu, Lei Qi, Yu-bin Wang, Xiu-juan Li, Ma-li Zheng, Rui-sheng Zhong, Yi Zhang, Xiang-dong Xu, Bo-le Wu, Zhu-mei Xu, Xiang-hong Lu

“…Fasting blood glucose, serum total cholesterol, serum triglycerides, serum insulin, and serum FGF21 levels were estimated. …”
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Examining the impact of probiotic Lactiplantibacillus pentosus 6MMI on inhibiting biofilm formation, adhesion, and virulence gene expression in Listeria monocytogenes ATCC 19115 by Behrooz Alizadeh Behbahani, Mostafa Rahmati-Joneidabad, Morteza Taki

“…Notably, Lpb. pentosus demonstrated significant hydrophobicity (71.89 %), auto-aggregation (42.39 %), co-aggregation (51.28 %), antioxidant activity (ranging from 42.29 % to 64.61 %), and a cholesterol reduction capacity of 50.31 %. Its competitive abilities against Listeria monocytogenes were quantified, showing a competition rate of 54.51 %, displacement rate of 48.57 %, and inhibition of adhesion at 27.71 %. …”
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The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic dysfunction-associated steatotic liver disease by Farshad Amirkhizi, Mahdiyeh Taghizadeh, Banafshe Khalese-Ranjbar, Soudabeh Hamedi-Shahraki, Somayyeh Asghari

“…Results Serum Sirt-1 levels was significantly lower in the MASLD group (p < 0.001) and was inversely correlated with serum insulin (r = -0.163, p = 0.025), HOMA-IR (r = -0.169, p = 0.020) and triglyceride (r = -0.190, p = 0.009) and positively correlated with serum levels of high-density lipoprotein cholesterol (HDL-C) (r = 0.214, p = 0.003). The area under the curve (AUC) of Sirt-1 to predict the presence of MASLD was 0.76 (p < 0.001, 95% CI: 0.69, 0.82) with a sensitivity of 78.9, specificity of 61.1, positive predictive value (PPV) of 67.0%, and negative predictive value (NPV) of 74.0%. …”
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Inflammatory Biomarkers and Lipid Parameters May Predict an Increased Risk for Atrial Arrhythmias in Patients with Systemic Sclerosis by Veronika Sebestyén, Dóra Ujvárosy, Balázs Ratku, Hajnalka Lőrincz, Sára Csiha, Dóra Tari, Gyöngyike Majai, Sándor Somodi, Gabriella Szűcs, Mariann Harangi, Zoltán Szabó

“…Lipid parameters, such as Apo A-I, LDL-cholesterol (LDL-C), oxidized LDL (oxLDL) and the LDL and HDL subfractions were also evaluated. …”
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