The state of lipid metabolism on the background of the use of ω -3 fatty acids in high-altitude conditions by Gulbarchyn Alisherovna Asrankulova, Zhyldyz Akmatovna Makhmudova, Zyinat Samidinovna Boronova, Meerim Taalaibekovna Taalaibekova, Zhyldyz Turusbekovna Ayipova, Unsun Satarkulovna Torobaeva

“…There was a significant increase in total cholesterol and triglyceride levels, indicating disturbances in lipid metabolism and may be indicative of hyperlipidemia. …”
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Investigation of the healing effects of Afyon Province hot spring waters on experimentally-induced fatty liver in mice by Bülent Elitok, Ibrahim Kişlalioğlu, Yavuz Ulusoy, Bahadır Kilinç

“…On day 21 of the experiment, the animals of the experimental group demonstrated a significant (p < 0.05) decrease in the total number of leukocytes, neutrophils, monocytes, as well as in the levels of aspartate aminostatesferase, alanine aminopenesferase, gamma-glutamyltransferase, low-density lipoproteins, total cholesterol, triglycerides. There was also an increase in erythrocyte, hemoglobin, hematocrit, total protein, albumin and high density lipoprotein levels (p < 0.05). …”
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Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models by Chrystal Paulos, Gregory B Lesinski, Zachary S Buchwald, Nabil F Saba, Vikash Kansal, Andre J Burnham, Brendan L C Kinney, Nicole C Schmitt

“…Emerging data suggest that manipulation of cholesterol may enhance some aspects of antitumor immunity.Methods We used syngeneic murine models (mouse oral cancer, MOC1 and TC-1) to investigate our hypothesis that a subset of statin drugs would enhance antitumor immunity and delay tumor growth.Results Using an ex vivo coculture assay of murine cancer cells and tumor infiltrating lymphocytes, we discovered that all seven statin drugs inhibited tumor cell proliferation. …”
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A prediction model for high-risk cardiovascular disease among residents aged 35 to 75 years by ZHOU Guoying，XING Lili，SU Ying，LIU Hongjie，LIU He，WANG Di，XUE Jinfeng，DAI Wei，WANG Jing，YANG Xinghua，

“…Multivariable logistic regression analysis showed that gender, age, smoking, central obesity, systolic blood pressure, fasting blood glucose, triglyceride and low-density lipoprotein cholesterol were influencing factors for high-risk CVD among residents aged 35 to 75 years (all P<0.05). …”
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Association between the atherogenic index of plasma and long-term risk of type 2 diabetes: a 12-year cohort study based on the Japanese population by Qianxing Zhou, Yamei Wu, Mingkang Li

“…The AIP was calculated using the formula log [triglyceride (mmol/L)/high-density lipoprotein cholesterol (mmol/L)]. Cox proportional hazard regression models were employed to assess the association between AIP and T2D risk. …”
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Hepatoprotective Effects of Crude Stem Bark Extracts and Solvent Fractions of Cordia africana against Acetaminophen-Induced Liver Injury in Rats by Gudeta Duga Geresu, Shemsu Umer, Mahlet Arayaselassie, Genet Ashebir, Eyasu Makonnen

“…Oral administration of APAP resulted in a significant increase in serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), TB, low-density lipoprotein (LDL), total cholesterol (TC), and triglycerides (TGs) and decrease in serum high-density lipoprotein (HDL). …”
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Effect of Cannabis Seeds on Some Biomedical Parameters in Male Rats by Karwan Anwar Hassan, Salah Omer Hamabor, Hunar Mustafa Wassman

“…Enzymes Alkaline phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT) as well as creatinine, uric acid and very low-density lipoprotein (VLDL) were not significantly (p<0.05) different in both groups. Level of Cholesterol, triglyceride and c-reactive protein were significantly (p<0.05) reduced. …”
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Antiulcer Effect of Genus Symphytum L. and Portulaca oleracea L. as Investigated on Experimental Animals by El-Sayed H. Bakr, Amal Al-Ghamdi, Reham Al-Amri, Muna Al-Otaibi, Nada Al-Saad, Ghala Al-Matrafi, Ziad T. Kishmira, Firas Azzeh, Areej A. Almuraee

“…The results showed that orally administered with genus Symphytum L. and Portulaca oleracea L. significantly reduced the length of gastric ulcer, gastric juice volume, and total acidity of gastric juice, in addition to decreasing total cholesterol (TC), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), RBC, WBC, HGB, and PLT. …”
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Supplementation of Multistrain Probiotics Improves Milk Production, Blood Metabolites, Digestibility, and Rectal Microbiota during the Prepartum and Early Lactation Stages in Cross... by Mohamed S. Ayyat, Usama M. Abdel Monem, Gamal Abdel-Rahman, Adel Ibrahim Hussein, Hamdy A. El-Nagar, Wael M. Wafa, Samir Mahgoub, Adham A. Al-Sagheer

“…Serum biochemical measurements showed lower serum concentrations of LDL, total cholesterol, and VLDL in MPF-fed cows than in the control group. …”
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Prevalence of dyslipidaemia and transaminitis in obese 8 to 18-year-old in Eastern India by Ghose N, Sur K, Sahana D

“…There was significant correlation of BMI with triglycerides, total cholesterol, VLDL, non-HDL-C and AST. Conclusion: Obese children have a high prevalence of dyslipidaemia and transaminitis. …”
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Effects of Pioglitazone on Asymmetric Dimethylarginine and Components of the Metabolic Syndrome in Nondiabetic Patients (EPICAMP Study): A Double-Blind, Randomized Clinical Trial by Pedram Shokouh, Adel Joharimoghadam, Hamidreza Roohafza, Masoumeh Sadeghi, Allahyar Golabchi, Maryam Boshtam, Nizal Sarrafzadegan

“…Compared with the placebo group, alanine and aspartate transaminases were decreased and high-density lipoprotein cholesterol was increased after treatment with pioglitazone. …”
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Inulin Reduces Kidney Damage in Type 2 Diabetic Mice by Decreasing Inflammation and Serum Metabolomics by Jiayuan He, Xiang Li, Man Yan, Xinsheng Chen, Chang Sun, Jiajun Tan, Yinsheng Song, Hong Xu, Liang Wu, Zhengnan Yang

“…After 12 weeks, the administration of inulin resulted in decreased serum levels of fasting blood glucose (FBG), low-density lipoprotein cholesterol (LDL-C), blood urea nitrogen (BUN), and creatinine (CRE). …”
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Prevalence of iron deficiency in type 2 diabetes mellitus patients and its association with altered lipid profile by Arindam Naskar, Agnibho Mondal, Indranil Dhar

“…However, significant associations were observed between iron deficiency and lower total cholesterol levels, low-density lipoprotein, and triglycerides. …”
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Impact of Lonicera hypoglauca leaf inclusion on immune and antioxidant responses in geese by Zonghao Lv, Zhen Li, Zhizhong Zhang, Gao Li, Qinghua Chen, Qian Lin

“…However, 12% LHL substitution abnormally altered the serum levels of various biochemical parameters, such as total protein, total cholesterol, urea, triglyceride and low-density lipoprotein (p < 0.05). …”
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Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease by Tsuneo Takenaka, Takahiko Sato, Hitoshi Hoshi, Nobutaka Kato, Keita Sueyoshi, Masahiro Tsuda, Yusuke Watanabe, Hiroshi Takane, Yoichi Ohno, Hiromichi Suzuki

“…Our findings implicated that high AI, the presence of diabetes, and low high-density lipoprotein cholesterol were significant contributors to cardiovascular events. …”
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Risk Factors for Macro- and Microvascular Complications among Older Adults with Diagnosed Type 2 Diabetes: Findings from The Irish Longitudinal Study on Ageing by Marsha L. Tracey, Sheena M. McHugh, Anthony P. Fitzgerald, Claire M. Buckley, Ronan J. Canavan, Patricia M. Kearney

“…Older age, being male, a history of smoking, a lower level of physical activity, and a diagnosis of high cholesterol were independent predictors of macrovascular complications. …”
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Lipid-lowering drug targets and lung related diseases: a Mendelian randomization study by Haifeng Yu, Xiaofei Zhang, Bian Wen, Shuo Hu, Bin Ni

“…METHODS We extracted genetic variations of six drug target genes from a major genome-wide association study of low-density lipoprotein cholesterol (LDL-C) in individuals predominantly of European ancestry to represent the effects of LDL-C-lowering treatment. …”
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The Use of Perovskia abrotanoides Extract in Ameliorating Heat Stress-Induced Oxidative Damage and Improving Growth Efficiency in Carp Juveniles (Cyprinus carpio) by Hossein Adineh, Saeed Zahedi, Morteza Yousefi, Zeynab Sedaghat, Sevdan Yilmaz, Ebrahim Gholamalipour Alamdari, Mohammad Farhangi

“…Serum cortisol, glucose, triglyceride, cholesterol, and malondialdehyde levels as well as catalase, alanine aminotransferase, and aspartate aminotransferase activities were significantly decreased generally in all PAE-supplemented groups compared to the control groups before and/or after high-temperature stress (32°C). …”
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Helicobacter pylori CagA promotes gastric cancer immune escape by upregulating SQLE by Sifan Liu, Nan Zhang, Xu Ji, Shuyue Yang, Zheng Zhao, Peng Li

“…This study revealed that H. pylori CagA upregulated squalene epoxidase (SQLE) expression, a key enzyme in the cholesterol biosynthesis pathway. Elevated SQLE activity increased cellular palmitoyl-CoA levels, enhancing PD-L1 palmitoylation while decreasing its ubiquitination. …”
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Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81 by Gérard Vergoten, Christian Bailly

“…Methods: The interaction of Hz-A/B with CD81 has been modeled, using structures of the cholesterol-bound full-length protein and a truncated protein corresponding to the LEL portion. …”
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