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461
Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population
Published 2013-01-01“…Levels of fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDLC) were determined by enzymatic methods, while low-density lipoprotein cholesterol (LDLC) was calculated. …”
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462
Antioxidant Potential, Subacute Toxicity, and Beneficiary Effects of Methanolic Extract of Pomelo (Citrus grandis L. Osbeck) in Long Evan Rats
Published 2019-01-01“…However, rats which received 1000 mg/kg dose had a significant reduction in some serum parameters, including alanine transaminase (15.29%), alkaline phosphatase (2.5%), lactate dehydrogenase (15.5%), γ-glutamyltransferase (20%), creatinine (14.47%), urea (18.50%), uric acid (27.14%), total cholesterol (5.78%), triglyceride (21.44%), low-density lipoprotein cholesterol (40.74%), glucose (2.48%), and all atherogenic indices including cardiac risk ratio (24.30%), Castelli’s risk index-2 (45.71%), atherogenic coefficient (42%), and atherogenic index of plasma (25%) compared to control. …”
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463
Genetic Markers Associated to Dyslipidemia in HIV-Infected Individuals on HAART
Published 2013-01-01“…APOE (rs429358 and rs7412) genotypes and APOA5 −1131T>C (rs662799) were associated with plasma triglycerides (TG) and low-density-lipoprotein cholesterol levels (LDL-C). The APOA5 −1131T>C (rs662799) and SCAP 2386A>G (rs12487736) polymorphisms were significantly associated with high-density-lipoprotein cholesterol levels. …”
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464
Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2
Published 2025-01-01“…Abstract Background Patients with the genetic disorder Niemann-Pick type C2 disease (NP-C2) suffer from lysosomal accumulation of cholesterol causing both systemic and severe neurological symptoms. …”
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465
Comparative cardiometabolic safety and effectiveness of aripiprazole in people with severe mental illness: A target trial emulation.
Published 2025-01-01“…The primary outcome was total cholesterol at 1 year (cardiometabolic safety). The main secondary outcome was psychiatric hospitalisation (effectiveness). …”
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466
Deletion of sphingosine 1-phosphate receptor 1 in myeloid cells reduces hepatic inflammatory macrophages and attenuates MASH
Published 2025-02-01“…MASH was established by feeding mice a high-fat, -fructose, and -cholesterol (FFC) diet for 24 weeks, which led to the development of steatohepatitis and MASH-defining cardiometabolic risk factors. …”
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467
Therapeutic effect and potential mechanism of Fufang Danshen dripping pills for stable coronary heart disease: a randomized controlled trial
Published 2025-01-01“…Additionally, we evaluated the patients' Seattle Angina Questionnaire score, blood pressure, circulating levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, C-reactive protein, platelets, alanine aminotransferase, aspartate aminotransferase, serum creatinine, and fasting blood glucose as the secondary outcomes. …”
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468
Biochemical study of striped catfish Pangasianodon hypophthalmus broodstock induced by PMSG hormone + anti‒dopamine and turmeric addition
Published 2018-07-01“…In HKu treatment, the cholesterol value was higher than the control treatment. …”
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469
The effect of the fenugreek hydrolyzed protein on lipid profile in patients with mild-to-moderate hypercholesterolemia: A confirmatory triple-blind randomized-controlled clinical t...
Published 2025-02-01“…Background: The risk of coronary artery disease in people with high serum cholesterol is more than twice as high as in those with moderate serum cholesterol. …”
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470
All-Cause Mortality Risk of Metabolically Healthy Obese Individuals in NHANES III
Published 2012-01-01“…Metabolic health was defined as: (1) homeostasis model assessment-insulin resistance (HOMA-IR) <2.5; (2) ≤2 Adult Treatment Panel (ATP) III metabolic syndrome criteria; (3) combined definition using ≤1 of the following: HOMA-IR ≥1.95 (or diabetes medications), triglycerides ≥1.7 mmol/L, HDL-C <1.04 mmol/L (males) or <1.30 mmol/L (females), LDL-C ≥2.6 mmol/L, and total cholesterol ≥5.2 mmol/L (or cholesterol-lowering medications). …”
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471
Response Rate and Impact on Lipid Profiles of Obeticholic Acid Treatment for Patients with Primary Biliary Cholangitis: A Meta-Analysis
Published 2021-01-01“…Besides, OCA significantly decreased total cholesterol (P=0.02) with no heterogeneity (P=0.87, I2 = 0%) and high-density lipoprotein levels (P<0.05) with no heterogeneity (P=0.82, I2 = 0%). …”
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472
Whole-Body Cryotherapy Decreases the Levels of Inflammatory, Oxidative Stress, and Atherosclerosis Plaque Markers in Male Patients with Active-Phase Ankylosing Spondylitis in the A...
Published 2018-01-01“…In both groups, the total cholesterol and LDL cholesterol, triglycerides, sCD40L, PAPP-A, and PLGF levels decreased, but the parameter changes were higher in the WBC group. …”
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473
Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial
Published 2025-01-01“…In HD patients, significant reductions were observed in LDL cholesterol (p=0.04) and total plasma cholesterol levels (p=0.01) after TRF intervention. …”
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474
Physicochemical Characterisation and Potential Uses of Oils From the Entrails of Nile Tilapia From Different Farming Sites in Ghana
Published 2025-01-01“…The refractive index, fatty acid profile, colour and cholesterol content of the TFO samples (TFS1, TFS2, TFS3 and TFS4) were determined using a refractometer, GC–MS, chromameter and UV spectrophotometer, respectively. …”
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475
MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma
Published 2025-01-01“…Abstract Cholesterol metabolism is abnormally active in tumour cells. …”
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476
Arterial Stiffness in Nonhypertensive Type 2 Diabetes Patients in Ghana
Published 2016-01-01“….; all p<0.05); the determinants of CAVI were diabetes status, age, BMI, heart rate, HbA1c, total cholesterol, HDL cholesterol, and previous smoking status (β = 0.21, 0.38, 0.2, 0.18, 0.24. 0.2, −0.19, and 0.2, resp.; all p<0.05). …”
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477
New era, new GOALs: cardiovascular screening and lipid management in cystic fibrosis
Published 2025-02-01“…Background: Cardiovascular disease (CVD) risks are increasing in people with cystic fibrosis (pwCF). While cholesterol levels were historically low in pwCF, higher levels after initiating highly effective modulator therapy (HEMT) have been reported. …”
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478
Risk factor clusters for non-communicable diseases in adolescents in Eastern Cape, South Africa
Published 2025-01-01“…Data included body mass index (BMI), blood pressure (BP), cholesterol, glucose levels, and perceived stress (via the Perceived Stress Scale). …”
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479
Lipidomics-based investigation of its impact on the pathogenesis of coronary atherosclerosis: a Mendelian randomization study
Published 2025-02-01“…Results Through IVW, MR-Egger and weighted median regression methods, we inferred that these six lipid metabolites: cholesterol levels, sterol ester (27:1/18:2) levels, triacylglycerol (52:4) levels, triacylglycerol (52:5) levels, diacylglycerol (18:1_18.2) levels, triacylglycerol (53:4), could directly impact the development of atherosclerosis. …”
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480
Protein hydrolysates of niosome-encapsulated skipjack (Katsuwonus pelamis) viscera: Antioxidant, anticancer, and release properties
Published 2025-06-01“…Additionally, the study investigated the stabilization of FPH by partially replacing cholesterol with cholecalciferol and squalane in nano-sized niosomes. …”
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