Beyond BRAFV600E: Investigating the Clinical and Genetic Spectrum of Langerhans Cell Histiocytosis in Children by Xue Tang, Ju Gao, Xia Guo, Zhi Wan, Jing‐jing Sun

“…Currently, the correlation between clinical phenotypes and molecular alterations in childhood LCH, besides the BRAFV600E mutation, has not been sufficiently studied. …”
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Neuroanatomical and functional substrates of the short video addiction and its association with brain transcriptomic and cellular architecture by Yuanyuan Gao, Ying Hu, Jinlian Wang, Chang Liu, Hohjin Im, Weipeng Jin, Wenwei Zhu, Wei Ge, Guang Zhao, Qiong Yao, Pinchun Wang, Manman Zhang, Xin Niu, Qinghua He, Qiang Wang

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Pooled prevalence and associated factors of traditional uvulectom among children in Africa: A systematic review and meta-analysis. by Solomon Demis Kebede, Kindu Agmas, Demewoz Kefale, Amare Kassaw, Tigabu Munye Aytenew

“…<h4>Background</h4>Traditional childhood uvulectomy (TCU) is an unregulated cultural practice associated with significant health risks, including infections, anemia, aspiration, and oral or pharyngeal injuries. …”
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Cardiovascular Disease Screening in Primary School Children by Alena Bagkaki, Fragiskos Parthenakis, Gregory Chlouverakis, Emmanouil Galanakis, Ioannis Germanakis

“…Background: Screening for cardiovascular disease (CVD) and its associated risk factors in childhood facilitates early detection and timely preventive interventions. …”
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Comparing the Effects of Integrative Neuromuscular Training and Traditional Physical Fitness Training on Physical Performance Outcomes in Young Athletes: A Systematic Review and Me... by Ke-wen Wan, Zi-han Dai, Po-san Wong, Robin Sze-tak Ho, Bjorn T. Tam

“…Abstract Background Enhancing youth's physical fitness levels during childhood and adolescence through prior training programs can significantly optimize their athletic performance. …”
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Three Unrelated Patients of Roma Ethnicity from a Single Center Carrying the Same Deletion in <i>MYD88</i> Gene: A Founder Effect? by Roberta Romano, Francesca Cillo, Laura Grilli, Alessio Ciaccio, Lorenzo Bufalo, Elisabetta Toriello, Antonio De Rosa, Carmen Rosano, Emilia Cirillo, Giancarlo Blasio, Marika Comegna, Carmela Di Domenico, Giuseppe Castaldo, Claudio Pignata, Giuliana Giardino

“…Half of the reported patients belong to Roma descent, an itinerant ethnic group living mostly in Europe, with an increased risk of childhood mortality due to limited access to healthcare services. …”
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Impact of the severity and extension of dental caries lesions on Turkish preschool children’s oral health-related quality of life: a cross-sectional study by Ayça Kurt, Damla Bolat, Ömer Hatipoğlu

“…This study aims to evaluate the relationship between extension of dental caries lesions and OHRQoL in children aged 3–6 years using the Early Childhood Oral Health Impact Scale (ECOHIS). Methods This cross-sectional study involved 300 children aged 3–6 years and their parents or caregivers. …”
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The role of the hippocampus in working memory and word reading: Novel neural correlates of reading among youth living in the context of economic disadvantage by ET. Marcelle, H. Yang, JW. Cohen, B. Ramphal, D. Pagliaccio, V. Rauh, BS. Peterson, F. Perera, H. Andrews, AG. Rundle, J. Herbstman, AE. Margolis

“…Using a cross-sectional developmental design, we explored this in middle childhood (average age at MRI scan ∼10; N = 50) and adolescence (average age at MRI scan ∼17; N = 175). …”
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Evaluating a targeted selective speech, language, and communication intervention at scale – Protocol for the Happy Talk cluster randomised controlled trial. [version 3; peer review... by Pauline Frizelle, Darren Dahly, Aoife O'Shea, Aileen Murphy, Cristina McKean

“…The Happy Talk trial tests if a community embedded, targeted selective speech and language programme that simultaneously engages with parents and early childhood educators, (1) improves language outcomes in children aged between 2 years 10 months and 6 years and (2) is cost effective for the health care system. …”
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Traumatic dental injuries in the first year of life and related risk factors in three regions of Brazil: a multicenter birth cohort study by Carlos Alberto Feldens, Bruno Antonio Sehn Konzen, Elisa Maria Rosa de Barros Coelho, Alessandra Castro Alves, Eliane Gerson Feldens, Márcia Regina Vítolo, Paulo Floriani Kramer

“…Abstract Background Traumatic dental injuries (TDIs) in early childhood exert a negative impact on the quality of life of children and their families. …”
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Germ cell quantification in human fetal and prepubertal testis tissues: a comparison of current methodologies by Emma Kearney, David Greenald, Gabriele Matilionyte, Sheila Lane, Melissa D Tharmalingam, Jill Davies, Jan-Bernd Stukenborg, Grace Forsyth, Rod T Mitchell

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Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled Trials by Waleed T Batais, Nada O Taher, Abeer K Alhindi, Abdullah A Ghaddaf, Anas Alamoudi, Sarah A Al-Ghamdi, Jumanah J Homsi, Hashem S Almarzouki, Mansour A Qurashi

“…Objective Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness in preterm infants with low birth weight. …”
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Individual and community level maternal factors for zero-dose children in Ethiopia using mini-EDHS 2019: a mixed effects model by Anteneh Kassa Yalew, Werkneh Melkie Tilahun, Meron Asmamaw Alemayehu, Tigabu Kidie Tesfie, Muluken Chanie Agimas, Mekuriaw Nibret Aweke, Worku Necho Asferie, Moges Tadesse Abebe

“…Introduction Zero-dose children refer to a child who has not yet received any childhood vaccines. Globally, zero-dose children are the major public health problem. …”
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Caregiver Global Impression Observations from EMBARK: A Phase 3 Study Evaluating Delandistrogene Moxeparvovec in Ambulatory Patients with Duchenne Muscular Dystrophy by Craig M. McDonald, Jacob S. Elkins, Sai Dharmarajan, Katherine Gooch, Teofil Ciobanu, Claire J. Lansdall, Alexander P. Murphy, Fiona McDougall, Eugenio M. Mercuri, Ivana Audhya, the EMBARK Study Group

“…Abstract Introduction Duchenne muscular dystrophy (DMD) is a rare, progressive, debilitating neuromuscular disease. The early childhood onset and debilitating nature of the disease necessitate decades of caretaking for most patients. …”
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Refining management strategies for Lennox–Gastaut syndrome: Updated algorithms and practical approaches by Stéphane Auvin, Alexis Arzimanoglou, Mercè Falip, Pasquale Striano, J. Helen Cross

“…Plain Language Summary Lennox–Gastaut syndrome (LGS) is a severe type of epilepsy that usually starts in childhood but continues into adulthood. It is characterized by a variety of different types of seizures (abnormal electrical activity in the brain), which are difficult to treat and often cause people with the condition to fall and injure themselves. …”
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Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK by Gouia I, Joulain F, Zhang Y, Morgan CL, Khan AH

“…Imène Gouia,1 Florence Joulain,1 Yi Zhang,2 Christopher Ll Morgan,3 Asif H Khan4 1HEVA (Health Economics and Value Assessment), Sanofi, Gentilly, France; 2Medical Affairs, Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA; 3Epidemiology, Pharmatelligence Ltd, Cardiff, UK; 4Global Medical, Sanofi, Bridgewater, NJ, USACorrespondence: Imène Gouia, Sanofi, 82 Avenue Raspail, Gentilly Cedex, 94255, France, Tel +33786980603, Email Imene.Gouia@sanofi.comBackground: UK pediatric asthma prevalence is among the highest in Europe, and although the clinical and economic burden of asthma in UK adults is well described, childhood asthma data is lacking. We assessed the clinical and economic burden of asthma in children in the UK to better understand the impact of pediatric asthma.Methods: This was a retrospective, case-matched, longitudinal analysis using the Clinical Practice Research Datalink GOLD database and linked patient-level data (Hospital Episode Statistics and Office for National Statistics datasets) of selected patient (aged 6– 11 years) records in 2017. …”
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A Review of Treatment Methods and Available Therapies for Individuals with ADHD by Zuzanna Gałuszka, Natalie Papachristoforou, Daria Michałka, Monika Makar, Tomasz Bartuś, Żaneta Góra, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan, Radosław Chmiel

“…This review explores treatment approaches and therapies for Attention Deficit Hyperactivity Disorder (ADHD), a neurodevelopmental condition affecting adults, with symptoms often persisting from childhood into adulthood. The research examines the efficacy, tolerability, and accessibility of pharmacological and psychosocial interventions. …”
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Corporal Punishment of Children in Nine Countries as a Function of Child Gender and Parent Gender by Jennifer E. Lansford, Liane Peña Alampay, Suha Al-Hassan, Dario Bacchini, Anna Silvia Bombi, Marc H. Bornstein, Lei Chang, Kirby Deater-Deckard, Laura Di Giunta, Kenneth A. Dodge, Paul Oburu, Concetta Pastorelli, Desmond K. Runyan, Ann T. Skinner, Emma Sorbring, Sombat Tapanya, Liliana Maria Uribe Tirado, Arnaldo Zelli

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Annexin V+ Microvesicles in Children and Adolescents with Type 1 Diabetes: A Prospective Cohort Study by Vibeke Bratseth, Hanna D. Margeirsdottir, Gemma Chiva-Blanch, Martin Heier, Svein Solheim, Harald Arnesen, Knut Dahl-Jørgensen, Ingebjørg Seljeflot

“…The cohort included type 1 diabetics (n=40) and healthy controls (n=40), mean age 14 years (range 11) at inclusion, randomly selected from the Norwegian Atherosclerosis and Childhood Diabetes (ACD) study. Citrated plasma was prepared and stored at -80°C until cMV analysis by flow cytometry. …”
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Australian children’s foot, ankle and leg problems in primary care: a secondary analysis of the Bettering the Evaluation and Care of Health (BEACH) data by Hylton B Menz, Christopher Harrison, Peter A Lazzarini, Cylie M Williams, Julie Gordon

“…This data highlights the importance of initiatives supporting contemporary primary care knowledge of diagnoses and management of paediatric lower limb problems to minimise childhood burden of disease.…”
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