Long-term Outcome of Vascularized Fibular Bone Graft Reconstruction for Upper Limb Osteosarcoma: A Case Report by Revanth Thiruvarul Selvan, Gutta Charith, Viveksheel Bhatti, Gopinath Menon

“…Materials and methods: This is a case report of a 34-year-old female who underwent left proximal humerus osteosarcoma wide excision and reconstruction with free vascularized fibula graft and chemotherapy 12 years back. During these 12 years, the patient had gradual improvement in her movements in her left upper limb and overall outcome. …”
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Insights from in vivo preclinical cancer studies with histotripsy by Tejaswi Worlikar, Timothy Hall, Man Zhang, Mishal Mendiratta-Lala, Michael Green, Clifford S. Cho, Zhen Xu

“…Research is underway to combine histotripsy with immunotherapy and chemotherapy to improve therapeutic outcomes. In addition to preclinical cancer research, human clinical trials are ongoing for the treatment of liver tumors and renal tumors. …”
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A study on the expression of Her2/neu in malignant epithelial ovarian tumors by Amit Kumar Bhardwaj, Vanita Bhaskar, Rashmi Nayak, Anubhav Chandrakar, Vikas Bombeshwar, Vikas Kailashiya

“…This variability may be associated with chemotherapy resistance and poor treatment outcomes, thereby playing a significant role in prognosis. …”
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Epigenetic profiling for prognostic stratification and personalized therapy in breast cancer by Xiao Guo, Chuanbo Feng, Jiaying Xing, Yuyan Cao, Tengda Liu, Wenchuang Yang, Runhong Mu, Tao Wang

“…High-MLEM patients showed poorer prognosis but were more responsive to chemotherapy, with vincristine identified as a promising therapeutic option. …”
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A Rare Form of Melanoma Masquerading as a Diabetic Foot Ulcer: A Case Report by Susan Thomas, Yuan-Xiang Meng, Vijaykumar G. Patel, Gregory Strayhorn

“…The treatment included wide margin excision of the lesion with en bloc amputations of 4th and 5th toes, followed by adjuvant chemotherapy. Discussion. The development of ALM may potentially relate to diabetes as a reported higher prevalence of diabetes with ALM patients. …”
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Pulmonary Hypertension due to a Pulmonary Artery Leiomyosarcoma: A Case Report by Seyyed Hassan Adeli, Bardia Nemati, Mahboubeh Jandaghi, Mohammad Mahdi Riahi, Fatemeh Hosseinzadeh, Fatemeh Salarvand

“…She died 3 months later after one chemotherapy course. Conclusion. Initially, the patient underwent surgery due to pulmonary embolism but, during the operation, the observed mass increased the probability of pulmonary artery neoplasm. …”
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«SAVING» A TWO-STAGE LIVER RESECTION BY THE ALPPS TYPE by D. V. Sidorov, M. V. Lozhkin, L. O. Petrov, A. G. Isaeva

“…A gold standard for the treatment of metastases of colorectal cancer in the liver is combined treatment with postoperative or perioperative chemotherapy. Despite the improvement of antitumor drugs, the main condition for the successful treatment of patients with metastatic colorectal cancer is the operation in a radical volume, implying a macroscopic and microscopic absence of a residual tumor. …”
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Locally Advanced and Unresectable Cutaneous Squamous Cell Carcinoma: Outcomes of Concurrent Cetuximab and Radiotherapy by Robert M. Samstein, Alan L. Ho, Nancy Y. Lee, Christopher A. Barker

“…Advanced age and immune dysfunction are risk factors for cutaneous squamous cell carcinoma (cSCC) and often render patients with locally-advanced disease medically inoperable or surgically unresectable, but potentially curable with radiotherapy. Concurrent chemotherapy and radiotherapy may not be well tolerated in this population, but another systemic therapy may improve disease control. …”
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Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy by Giovanni Zagli, Giovanni Cianchi, Sara Degl'Innocenti, Jessyca Parodo, Lorenzo Bonetti, Paolo Prosperi, Adriano Peris

“…Patients were treated with surgical debridement, protective colostomy, hyperbaric oxygen therapy, and broad-spectrum antibacterial chemotherapy. Vacuum-assisted closure (VAC) therapy was applied to the wound with the aim to clean, decontaminate, and avoid abdominal compartmental syndrome development. …”
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Pembrolizumab as first-line treatment for recurrent and metastatic head and neck cancer – real-world single-centre data by Bogdana Patachi, Kristian H. Jensen, Anita Gothelf, Mogens Bernsdorf, Jeppe Friborg, Claus A. Kristensen

“…Background and purpose: The randomised clinical trial KEYNOTE-048 has demonstrated a significant increase in survival for patients with head and neck cancer treated with pembrolizumab with or without chemotherapy. The purpose of the present retrospective study was to investigate whether survival in a group of consecutive patients treated at our department was comparable to the results from KEYNOTE-048. …”
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Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain by Peng Xi, Rui Mao, Shiyan Wu, Lei Liu, Ceng Cai, Lei Lu, Cailin Zhang, Yimei Li

“…In the present study, we aimed to explore the therapeutic mechanisms of PD against chemotherapy-induced neuropathic pain. Methods. The putative targets of PD were obtained from the CTD and SwissTargetPrediction databases. …”
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Investigation of CD47 Expression in Renal Cell Tumors and Evaluation of Its Relationship with Prognostic Parameters by Ömer Faruk Dizibüyük, Zehra Bozdağ, Metin Karakök

“…Traditional treatments like chemotherapy and radiation are generally considered ineffective. …”
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Unusual Presentation of Testicular Cancer with Tumor Thrombus Extending to the Inferior Vena Cava by Marie Dusaud, Younes Bayoud, François-Régis Desfemmes, Benoît Molimard, Xavier Durand

“…After 4 courses of bleomycin, etoposide, and cisplatin (BEP) chemotherapy the patient’s tumor markers normalized and the thrombus disappeared. …”
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Paraneoplastic Limbic Encephalitis Resembling Acute Herpetic Encephalitis by Ioannis Markakis, Athanasios Papathanasiou, Ermioni Papageorgiou, Kostantinos Siarkos, Georgios Gkekas

“…The patient was treated with steroids and chemotherapy. Six months later, he had complete tumour remission and marked neurological improvement. …”
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Clinicopathological features and evaluation of microsatellite stability of colorectal carcinoma with cribriform comedo pattern by Tuğba Günler, Pinar Karabağli, Hicret Tiyek, Özge Keskin, Muslu K. Körez

“…Because this feature is important for planning adjuvant chemotherapy, it may be useful to identify cases, particularly with a cribriform comedo pattern >90%. …”
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Retroperitoneal Extraovarian Fibrothecoma Mimicking a Malignant Epithelial Ovarian Carcinoma by Patrick Roberts, Sharon Nofech-Mozes, Natalie Coburn, Paul Hamilton, Lilian T. Gien

“…This third case of extraovarian fibrothecoma highlights the importance of obtaining histologic evidence of malignancy prior to initiating neoadjuvant chemotherapy for a presumed ovarian cancer.…”
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Synchronous HPV-Related Cancer of Bilateral Tonsils Detected Using Transoral Endoscopic Examination with Narrow-Band Imaging by Fukuko Shimizu, Kenji Okami, Koji Ebisumoto, Daisuke Maki, Akihiro Sakai, Go Ogura, Naoya Nakamura, Masahiro Iida

“…He was treated with induction chemotherapy, bilateral radical tonsillectomy with neck dissection, and radiotherapy. …”
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Isolated Left Main Coronary Artery Stenosis after Thoracic Radiation Therapy: To Operate or Not to Operate by Osama Alsara, Ahmad Alsarah, Jagadeesh K. Kalavakunta, Heather Laird-Fick, George S. Abela

“…We report a case of radiation induced coronary artery disease in a 60-year-old female with a history of stage IIIA nonsmall cell lung carcinoma which was diagnosed eight years earlier and treated with chemotherapy and radiotherapy. She presented to the hospital with atypical chest pain that had occurred intermittently over the preceding week. …”
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Immunotherapy in colorectal cancer: Statuses and strategies by Yuan Li, Zewei Cheng, Shengli Li, Jiwei Zhang

“…Traditional treatment modalities for CRC, including surgery, chemotherapy, and radiotherapy, can be utilized either individually or in combination. …”
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Multiple Acrometastases in a Patient with Renal Pelvic Urothelial Cancer by Ryoko Sawada, Yusuke Shinoda, Aya Niimi, Tohru Nakagawa, Masachika Ikegami, Hiroshi Kobayashi, Sakae Tanaka, Yukio Homma, Nobuhiko Haga

“…After two regimens of chemotherapy, he suffered from pain on his wrist and ankle and swelling and hemorrhage of his toe. …”
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