Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome by Saba F. Ali, Rebecca J. Sonu, Denis M. Dwyre, Brian A. Jonas, Hooman H. Rashidi

“…The patient was successfully treated with chemotherapy and an autologous bone marrow transplant but subsequently developed a new FLT3-ITD negative t-MDS with a unique translocation, t(6;15)(q12;q15), three years after transplant. …”
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A Case of an Unusually Aggressive Cutaneous Anaplastic Large T-Cell Lymphoma in an HIV Patient Treated with CHOP by Jorge Hurtado-Cordovi, Louay Hanna, Vladimir Gotlieb, Alan S. Multz, Anastasia Pigal

“…Patient was treated with 6 cycles of CHOP (cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisone) chemotherapy and went into complete remission. Due to the aggressive course that this malignancy follows in HIV patients we suggest prompt treatment with systemic therapy.…”
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Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity by Naoya Harada, Ichiro Nobuhara, Noriko Haruta, Yumi Higashiura, Hideki Watanabe, Sumire Ohno

“…Interestingly, the tumor cells were immunoreactive for p53. Adjuvant chemotherapy was administered for the uterine corpus cancer and the patient remains healthy 48 months after the surgery. …”
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Two Synchronous Neonatal Tumors: An Extremely Rare Case by M. Rodríguez-Zubieta, K. Albarenque, C. Lagues, A. San Roman, M. Varela, D. Russo, G. Podesta, D. Steinberg, C. Schauvinhold, A. Etchegaray, M. T. G. de Dávila

“…The infant underwent surgery and chemotherapy in different steps. Complete surgical resection with clean margins is considered to be the best treatment option for sialoblastoma. …”
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Enhanced Expression of ABCB1 and Nrf2 in CD133-Positive Cancer Stem Cells Associates with Doxorubicin Resistance by Shinji Goto, Tsuyoshi Kawabata, Tao-Sheng Li

“…Complex mechanisms, including drug excretion and redox regulation, are likely involved in the DXR resistance of CD133-positive cells, suggesting the difficulty of drug resistance problem in cancer chemotherapy.…”
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Epiphyseal Primary Diffuse Large B-Cell Lymphoma of Bone by Shachar Kenan, Leonard Kahn, Morris Edelman, Arlene Redner, Samuel Kenan

“…The patient thus avoided further surgical intervention and received the appropriate treatment of chemotherapy, with subsequent rapid resolution of the lesion. …”
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circ_ZFR Is Linked to Paclitaxel Resistance in Cervical Cancer via miR-944 Sponging and IL-10 Upregulation by Xiaoqian Long, Meiyun Zheng, Youlin Yang, Yi Chen, Xiahui Zhang, Haiyan Zhang

“…Cervical cancer (CC) has an elevated rate of invasion and death despite surgical treatment, radiotherapy, and chemotherapy. Several studies revealed that circRNAs have a key contribution to the resistance of drugs against different types of carcinomas. …”
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Interfacial Engineering of Biocompatible Nanocapsules for Near‐Infrared‐Triggered Drug Release and Photothermal Therapy by Yuting Xie, Ze Yang, Hang Shen, Jingyi Chen, David A. Weitz, Dong Chen, Jianpeng Sheng, Tingbo Liang

“…Abstract Chemotherapy is an effective option for cancer treatment. …”
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Comprehensive Overview of Ketone Bodies in Cancer Metabolism: Mechanisms and Application by Ziyuan Liang, Lixian Deng, Xiaoying Zhou, Zhe Zhang, Weilin Zhao

“…The ketogenic diet (KD) may enhance the sensitivity of various cancers to standard therapies, such as chemotherapy and radiotherapy, by exploiting the reprogrammed metabolism of cancer cells and shifting the metabolic state from glucose reliance to KB utilization, rendering it a promising candidate for adjunct cancer therapy. …”
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The Efficacy of Ramucirumab in the Treatment of Gastric or Gastroesophageal Junction Cancer: A Meta-Analysis of RCTs by Hongqiong Yang, Yaojun Zhou, Liangzhi Wang, Tianyi Gu, Mengjia Lv, Jinling Sun, Chao Tu, Junbo He

“…Moreover, compared with the current first-line chemotherapy, the OS (OR=0.93, 95%CI=0.83–1.04, p=0.19) and PFS (OR=0.82, 95%CI=0.64–1.06, p=0.13) results were not significantly higher with RAM. …”
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Preparation of Ca-Mg Double-Doped Mesoporous Silica Nanoparticles and Their Drug-Loading and Drug-Releasing Properties by Qian Zhang, Jiamin Huang, Chao Liu, Ruihua Chen, Tao Jiang, Yusufu Hailili, Telieke Bahetibieke, Xiaohui Tang, Mei Wang

“…Breast cancer is a common clinical malignant tumor that seriously threatens women’s physical and mental health. Chemotherapy, as the first choice of breast cancer treatment, has limited its application in the clinic due to problems of poor stability, short half-life, and serious toxic side effects. …”
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Outcome of spine surgery in the context of spinal metastatic disease: The National Surgical Quality Improvement Program by Salim M. Yakdan, Maya Herrera, Nour Wehbe, Monifa Al Akoum, Muhammad Irfan Kaleem, Miguel A. Ruiz-Cardozo, Karan Joseph, Nada Assaf, Hani Dimassi

“…In addition, 28.6% of patients experienced a prolonged hospital stay, with significant predictors including chemotherapy, surgical urgency, dependent status, preoperative hematocrit, neurological deficits, preoperative albumin levels, and surgical complexity. …”
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A Case of Non-Small Cell Lung Cancer with Possible “Disease Flare” on Nivolumab Treatment by Shotaro Chubachi, Hiroyuki Yasuda, Hidehiro Irie, Koichi Fukunaga, Katsuhiko Naoki, Kenzo Soejima, Tomoko Betsuyaku

“…After 7 years from recurrence, 10th line chemotherapy, nivolumab, was initiated. Six weeks later, after 3 cycles of nivolumab treatment, rapid lung cancer progression was observed with an increase in the size of the primary lesion, multiple novel nodules on both lungs, and multiple novel brain metastases. …”
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An Innocent Appearing Subcutaneous Nodule Diagnoses a Small Cell Lung Cancer in a Never-Smoker Female by Nupur Sinha, Masooma Niazi, Gilda Diaz-Fuentes, Richard Duncalf

“…Platinum and etoposide chemotherapy with prophylactic cranial irradiation was initiated for advanced SCLC, and she required further irinotecan and taxol for subsequent pancreatic and adrenal metastases. …”
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Impact of Body Mass Index on Surgical and Oncological Outcomes in Laparoscopic Total Mesorectal Excision for Locally Advanced Rectal Cancer after Neoadjuvant 5-Fluorouracil-Based C... by Yanwu Sun, Pan Chi

“…Preoperative radiotherapy was delivered in 45–50.4 Gy/25f, 5 days/week, and concurrent chemotherapy using FOLFOX or CapeOX. Technical feasibility, postoperative and oncological outcome were compared between groups. …”
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Canine lung carcinoma—A descriptive review by Aleksandra Marcinowska, Aleksandra Marcinowska, Rodrigo Dos Santos Horta, Felisbina Queiroga, Felisbina Queiroga, Antonio Giuliano, Antonio Giuliano, Antonio Giuliano

“…Surgical excision of the primary tumor, along with resection of the affected locoregional lymph nodes is the preferred treatment option for most cases. Although chemotherapy, targeted therapy and radiation therapy have been employed, their effectiveness remain controversial. …”
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A review of leishmaniasis: current knowledge and future directions of heterocyclic molecules by Tejaswini Masne, Dileep Kumar, Deepali Bansode

“…The review also explores various therapies for leishmanial diseases, from chemotherapy to immunotherapy, and discusses their advantages and limitations. …”
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Exploring Strategies to Prevent and Treat Ovarian Cancer in Terms of Oxidative Stress and Antioxidants by Yanru Long, Houhui Shi, Jiatian Ye, Xiaorong Qi

“…On the one hand, the increased metabolism of ovarian cancer cells can lead to the increased production of ROS, and on the other hand, the impaired antioxidant defence system of ovarian cancer cells is not able to effectively scavenge the excessive ROS. In addition, chemotherapy and radiotherapy may elevate the oxidative stress in ovarian cancer cells. …”
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Case report: Relapse of intrathyroidal parathyroid carcinoma in a patient with novel variants in MET and CDKN1C genes by Ekaterina Kim, Anastasiia Lavreniuk, Olga Spasskaya, Anna Eremkina, Rustam Salimkhanov, Liliya Urusova, Natalia Tarbaeva, Sergey Popov, Victoria Zakharova, Natalia Mokrysheva

“…Other treatment options, such as chemotherapy or immunotherapy, are limited. Targeted therapy is considered a promising direction for disseminated tumors. …”
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Germinoma with Involvement of Midline and Off-Midline Intracranial Structures by Monica Graciela Loto, Karina Danilowicz, Santiago González Abbati, Rafael Torino, Alejandro Misiunas

“…A transsphenoidal biopsy identified a germinoma. Four cycles of chemotherapy with bleomicine, etoposide, and cysplatin were given, followed by radiotherapy, but patients died due to a recidiva. …”
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