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1721
The BCOR-rearranged sarcoma involving the lung: Diagnosis with clinical outcome and literature review
Published 2024-12-01“…The patient had a favorable response to the chemotherapy regime. BRS is an ultra-rare tumor, which rarely involves visceral organs. …”
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1722
Metastatic Tumor of the Spermatic Cord in Adults: A Case Report and Review
Published 2015-01-01“…Radical orchiectomy and adjuvant chemotherapy with S-1 were performed. No recurrence was found after one year of follow-up. …”
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1723
Multiple programmed cell death patterns predict the prognosis and drug sensitivity in gastric cancer
Published 2025-02-01“…Additionally, drug sensitivity analysis indicated that patients with a high PCDS may exhibit resistance to immunotherapy and standard adjuvant chemotherapy regimens; however, they may benefit from the FDA-approved drug Dasatinib.ConclusionOverall, we confirmed that the PCDS is a prognostic risk factor and a valuable predictor of immunotherapy response in GC patients, which provides new evidence for the potential application of GC.…”
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1724
Naturally Occurring Canine Invasive Urinary Bladder Cancer: A Complementary Animal Model to Improve the Success Rate in Human Clinical Trials of New Cancer Drugs
Published 2017-01-01“…Invasive urinary bladder cancer (invasive urothelial carcinoma (InvUC)) in dogs, for example, closely mimics the cancer in humans in pathology, molecular features, biological behavior including sites and frequency of distant metastasis, and response to chemotherapy. Genomic analyses are defining further intriguing similarities between InvUC in dogs and that in humans. …”
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1725
Solitary Spinal Epidural Metastasis from Gastric Cancer
Published 2016-01-01“…The patient had undergone total gastrectomy for gastric cancer followed by chemotherapy 8 months priorly. The whole body was examined for suspected metastatic spinal tumor, but no metastases of the spine or important organs were observed, and a solitary mass was present in the thoracic spinal epidural space. …”
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1726
Concordance of Peripheral Blood and Bone Marrow Next-Generation Sequencing in Hematologic Neoplasms
Published 2022-01-01“…We excluded cases in which chemotherapy or bone marrow transplant occurred in the interval between the two tests. …”
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1727
Characterization of rectum-colon cancer in Cienfuegos province from 1995 to 2000.
Published 2003-04-01“…There were patients in C Duke´s stage that did not received chemotherapy treatment.…”
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1728
Investigating the effect of femtosecond laser pulses on noscapine and curcumin cellular uptake and improving drug delivery in gastric cancer cells
Published 2025-01-01“…The MKN45 cell line, a type of gastric cancer cell, exhibits resistance to chemotherapy agents through various mechanisms. Curcumin and noscapine, two plant-derived anticancer compounds, exhibit selective cytotoxicity towards cancer cells. …”
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1729
A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection
Published 2018-01-01“…A 77-year-old male with a history of transurethral resection (TUR) of urothelial carcinoma (UC) of the bladder and adjuvant intravesical chemotherapy with pirarubicin 10 years ago revisited our department with a gross hematuria. …”
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1730
Stem cell status and prognostic applications of cuproptosis-associated lncRNAs in acute myeloid leukemia
Published 2025-01-01“…Stem cell research has highlighted the crucial role of long noncoding RNA (lncRNA) in regulating cellular differentiation and self-renewal processes, which are pivotal in AML pathogenesis and therapy resistance.MethodsThis study explores the relationship between cuproptosis-related lncRNAs and AML prognosis, providing novel insights into their impact on hematopoietic stem and progenitor cells.ResultsWe collected clinical information from 214 AML patients in our center and analyzed the association between granulocyte recovery after chemotherapy, cuproptosis, and prognosis. Additionally, we developed a prognostic model—the cuproptosis-associated long noncoding RNA prognostic model (CRLPM)—y analyzing data from The Cancer Genome Atlas (TCGA). …”
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1731
Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions
Published 2015-01-01“…There is no standard chemotherapy protocol for treatment of PBL. Cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP-like regimens have been the backbone while more intensive regimens such as cyclophosphamide, vincristine, doxorubicin, high-dose methotrexate/ifosfamide, etoposide, high-dose cytarabine (CODOX-M/IVAC), or dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (DA-EPOCH) are possible options. …”
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1732
Nonsmall Cell Lung Carcinoma with Giant Cell Features Expressing Programmed Death-Ligand 1: A Report of a Patient Successfully Treated with Pembrolizumab
Published 2018-01-01“…Giant cell carcinoma, a rare variant of nonsmall cell lung carcinoma (NSCLC), is characterized by aggressive progression and poor response to conventional chemotherapy. This report is the first to describe a patient with NSCLC and giant cell features who was successfully treated with pembrolizumab, an antibody targeting programmed death-1 (PD-1). …”
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1733
CD9 in acute myeloid leukemia: Prognostic role and usefulness to target leukemic stem cells
Published 2019-03-01“…First, we explored its prognostic role and its association with biological factors in a cohort of 112 AML patients treated with intensive chemotherapy. CD9 was expressed in 40% of AML and was associated with a favorable outcome (event‐free survival and relapse‐free survival) in univariate (P = 0.009 and P = 0.048, respectively) and multivariate (P = 0.004 and P = 0.039, respectively) analyses. …”
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1734
Mixed Adenoneuroendocrine Carcinoma Causing Colonic Intussusception
Published 2016-01-01“…The patient underwent right colectomy with primary anastomosis and adjuvant chemotherapy. The diagnosis of intussusception of the colon in adults is difficult because of its rarity and nonspecific clinical presentation. …”
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1735
Tactics of surgical treatment of the malignant heart tumors
Published 2019-06-01“…To achieve the conditional radicalism of the surgery and the maximum hemodynamic effect, it is necessary to use advanced techniques for reconstructing damaged cardiac structures in combination with active detoxification therapy and urgent chemotherapy.…”
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1736
Trans-Vessel Wall Cell Transplantation, Engraftment, and Tumor Access in the VX2 Rabbit Model
Published 2025-01-01“…The trans-vessel wall device (TW-device) is a new endovascular tool for precise and safe delivery of various payloads (cells, viral, modified RNA, chemotherapy, growth factors) in oncology and regenerative medicine. …”
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1737
A Case of Pneumothorax after Treatment with Lenvatinib for Anaplastic Thyroid Cancer with Lung Metastasis
Published 2018-01-01“…Pneumothorax during chemotherapy for a malignant tumor is considered a relatively rare complication. …”
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1738
Characterization of a Novel Tc-Carbonyl Complex as a Functional Probe of P-Glycoprotein Transport Activity
Published 2002-01-01“…Multidrug resistance (MDR) mediated by overexpression of MDR1 P-glycoprotein (Pgp) is one of the best characterized barriers to chemotherapy in cancer patients. Furthermore, the protective function of Pgp-mediated efflux of xenobiotics in various organs has a profound effect on the bioavailability of drugs in general. …”
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1739
Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural–Mesenchymal Transition
Published 2025-01-01“…Glioblastoma is one of the most aggressive brain cancers, characterized by active infiltrative growth and high resistance to radiotherapy and chemotherapy. Sesquiterpene triterpenoids (STLs) and their semi-synthetic analogs are considered as a promising source of novel anti-tumor agents due to their low systemic toxicity and multi-target pharmacological effects on key processes associated with tumor progression. …”
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1740
Progress in nanomedicine for sonodynamic immunotherapy of tumors
Published 2024-09-01“…Cancer remains a leading cause of mortality worldwide, with conventional treatments, such as chemotherapy and immunotherapy, exhibiting limitations, such as drug resistance and immune evasion. …”
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