Targeting Apoptosis Pathways in Cancer with Alantolactone and Isoalantolactone by Azhar Rasul, Muhammad Khan, Muhammad Ali, Jiang Li, Xiaomeng Li

“…This review suggests that alantolactone and isoalantolactone are potential promising anticancer candidates, but additional studies and clinical trials are required to determine their specific intracellular sites of actions and derivative targets in order to fully understand the mechanisms of therapeutic effects to further validate in cancer chemotherapy.…”
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Panoptosis – new frontier in research in head neck cancer by Shrikant B. Mali

“…Head and neck squamous cell carcinoma (HNSCC) is a common cancer that can develop resistance to therapeutic approaches, including chemotherapy, targeted therapy, and immunotherapy. PANoptosis, a non-apoptotic cell death mechanism, has been identified as a potential solution. …”
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Extracorporeal Ultrasound-Guided High Intensity Focused Ultrasound: Implications from the Present Clinical Trials by Tinghe Yu, Xiao Fu

“…Based upon evaluable data, the efficacy of HIFU was similar to that of radio frequency, chemoembolization, chemotherapy, radiotherapy, or hormone therapy; a combined therapy did not improve the efficacy. …”
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Refractory IgD Multiple Myeloma Treated with Daratumumab: A Case Report and Literature Review by Muhammad Husnain, Sandra Kurtin, Nikki Barkett, Irbaz bin Riaz, Amit Agarwal

“…We report a case of 40-year-old man with immunoglobulin D (IgD) multiple myeloma whose disease was refractory to at least 5 different chemotherapy regimens including proteasome inhibitors and immunomodulatory drugs. …”
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A Review on Colorectal Cancer and the Role of Traditional Chinese Herbal Medicine as Complementary Therapy by Jie Ji, Hiu Ching Phang, Xian Gu, Riyanto Teguh Widodo, Bey Hing Goh, Phei Er Kee, Siew-Keah Lee, Ashok Kumar Janakiraman, Long Chiau Ming, Kai Bin Liew

“…For many years, surgery and chemotherapy have been the mainstay treatments for cancer, but patients with metastatic disease have generally faced poor outcomes. …”
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Successful Treatment of Posttransplant EBV-Associated Lymphoma and Plasmacytoma Solely Localized to the CNS by Per Boye Hansen, Signe Ledou Nielsen

“…Considerable co-morbidity precluded intensive chemotherapy. The first patient with lymphoid CD20+ PTLD had a partial resection of her tumor performed. …”
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Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients by Ayse Rabia Senkaya, Sercan Kantarci, Suna Yildirim Karaca, Muzaffer Sanci

“…Hemoglobin A1c levels and fasting glucose were compared with cancer stage, grade, histological type, lymphovascular invasion, chemotherapy and radiotherapy data. Results: A statistically significant difference was found between the groups in terms of HbA1c values only according to the lymphovascular invasion (p=0.02). …”
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Bacteremia due to Leuconostoc pseudomesenteroides in a Patient with Acute Lymphoblastic Leukemia: Case Report and Review of the Literature by Kazuko Ino, Kazunori Nakase, Kei Suzuki, Akiko Nakamura, Atsushi Fujieda, Naoyuki Katayama

“…The patient developed a high fever despite antimicrobial therapy with doripenem after induction chemotherapy. After an isolate from blood cultures was identified as L. pseudomesenteroides, we changed the antibiotics to piperacillin-tazobactam and gentamicin, after which the patient recovered from the infection. …”
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Immune Response in Ovarian Cancer: How Is the Immune System Involved in Prognosis and Therapy: Potential for Treatment Utilization by Nikos G. Gavalas, Alexandra Karadimou, Meletios A. Dimopoulos, Aristotelis Bamias

“…Resistance to the disease occurs in more than 70% of the cases even after treated with chemotherapy agents such as paclitaxel- and platinum-based agents. …”
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Distant Ureteral Metastasis from Colon Adenocarcinoma: Report of a Case and Review of the Literature by Ferakis Nikolaos, Anastasopoulos Panagiotis, Bouropoulos Konstantinos, Samaras Vassilios, Poulias Iraklis

“…The patient died 6 months later due to toxic megacolon during chemotherapy. The differential diagnosis of ureteral adenocarcinoma, especially in patients with previous history of colon adenocarcinoma, should include the possibility of distant metastasis from the primary colonic tumor.…”
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Case report: Long term remission of metastatic sinonasal NUT carcinoma after palliative radiotherapy and immunotherapy in an elderly patient by Justin K. W. Ng, Edwin C. Y. Wong, Tommy C. Y. So, Raiden T. S. Wong

“…The mainstay of treatment consists of combination chemotherapy, surgical resection, and high dose radiation. …”
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Incisional Site Metastasis in a Patient with Cervical Carcinoma: A Case Report and Review of the Literature by C. Iavazzo, K. Madhuri, A. Tailor, S. Butler-Manuel

“…Wide excision was performed in 30/37 cases of which we have information regarding the treatment option, while 11/37 and 13/37 underwent radiotherapy and chemotherapy, respectively. The possible mechanism of such a metastasis as well as the treatment options is discussed.…”
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Treatment outcomes in NTM-PD in a high TB burden context by S. Kang, J.E. Schmidt, I. Chen, S. Tiberi

“…One study ( n = 24) demonstrated that resecting lesions and chemotherapy led to more favourable clinical outcomes. …”
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Is hyaluronan deposition in the stroma of pancreatic ductal adenocarcinoma of prognostic significance? by Florian Gebauer, Marius Kemper, Guido Sauter, Peter Prehm, Udo Schumacher

“…Recently the tumour stroma and in particular one of its main components, hyaluronan (HA), have attracted considerable attention as intravenous hyaluronidase treatment together with conventional chemotherapy considerably prolonged survival in HA-rich PDA patients. …”
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The characteristics of the tumor immune microenvironment in colorectal cancer with different MSI status and current therapeutic strategies by Qingzhe Wang, Min Yu, Shuang Zhang

“…Despite advancements in surgery, chemotherapy, and radiotherapy, the effectiveness of these conventional treatments is limited, particularly in advanced cases. …”
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Rituximab Monotherapy in the Management of a Rare Case of an HIV Associated Lymphoproliferative Disorder by Jason Hew, Fauzia Rana, Louise Zhou

“…It is used alone or in combination with chemotherapy to treat MCD. Case Report. We describe a case of a 58-year-old man with HIV and HHV-8 MCD and evidence of organ failure with a poor performance status that went into complete remission after four cycles of therapy with weekly rituximab. …”
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Metachronous Schnitzler’s Metastasis of Gastric Adenocarcinoma 13 Years After Curative Resection: A Case Report by Jun Kyeong Lim, Suk Bae Kim, Hyun Deok Shin

“…He had undergone a subtotal gastrectomy and chemotherapy for advanced gastric cancer 13 years earlier. …”
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Ovarian Cancer Prognostic Prediction Model Using RNA Sequencing Data by Seokho Jeong, Lydia Mok, Se Ik Kim, TaeJin Ahn, Yong-Sang Song, Taesung Park

“…Over 70% of ovarian cancer cases are high-grade serous ovarian cancers and have high death rates due to their resistance to chemotherapy. Despite advances in surgical and pharmaceutical therapies, overall survival rates are not good, and making an accurate prediction of the prognosis is not easy because of the highly heterogeneous nature of ovarian cancer. …”
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Advances in adjuvant therapy for operable N2 non-small cell lung cancer: a narrative review by Lei Liu, Yilong Mao, Leilei Guo, Chencong Li, Yiqian Wang

“…For NSCLC under this stage, the current treatment options are: preoperative neoadjuvant therapy, surgical treatment, postoperative adjuvant chemotherapy, postoperative adjuvant radiotherapy (PORT), Postoperative adjuvant targeted therapy and postoperative adjuvant immunotherapy. …”
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Metaplastic Carcinoma Breast in Polycythemic Octogenarian – Lessons Learnt: Case Report by Swarup Prabhu, Munish Malhotra, Naresh Saidha, Ritu Mehta, Surjeet Dwivedi, Tarun Mohan Gupta

“…Patient received preoperative hormonal therapy followed by modified radical mastectomy and postoperative adjuvant chemotherapy and hormonal therapy. Post operative patient showed good clinical recovery and was recurrence free at 6 months follow up although patient had all the poor prognostic factors with large size, LN involvement and high Ki 67. …”
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