Zeatin Elicits Premature Erythrocyte Senescence Through Calcium and Oxidative Stress Mediated by the NOS/PKC/CK1α Signaling Axis by Iman A. Alajeyan, Jawaher Alsughayyir, Mohammad A. Alfhili

“…In particular, zeatin (ZTN) delays cellular senescence of human fibroblasts and keratinocytes and exhibits anticancer activity. Chemotherapy-induced anemia is a major side effect of anticancer therapy secondary to premature senescence of red blood cells (RBCs). …”
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Inflammatory Pseudotumor of the Temporal Bone: Three Cases and a Review of the Literature by Huiqin Tian, Tingting Liu, Cong Wang, Lijun Tang, Zhibin Chen, Guangqian Xing

“…Another one underwent tympanomastoidectomy in combination with oral steroids, radiation, and chemotherapy, but the IP still recurred. A comprehensive review of the literature on clinical features of the temporal pseudotumor was conducted.…”
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Left Vocal Cord Paralysis Detected by PET/CT in a Case of Lung Cancer by Ali Ozan Oner, Adil Boz, Evrim Surer Budak, Gulnihal Hale Kaplan Kurt

“…The first PET/CT imaging revealed hypermetabolic mass in the left aortopulmonary region and hypermetabolic nodule in the anterior segment of the upper lobe of the left lung. After completing chemotherapy and radiotherapy against the primary mass in the left lung, the patient underwent a second PET/CT examination for evaluation of treatment response. …”
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High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb by Tiffany J. Pan, Liron Pantanowitz, Kurt R. Weiss

“…The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. …”
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PPARγ as a Novel Therapeutic Target in Lung Cancer by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…This review of the current literature highlights the potential of PPARγ agonists as novel therapeutic modalities in lung cancer, either as monotherapy or in combination with standard cytotoxic chemotherapy.…”
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Comparative safety profile of tyrosine kinase inhibitors in NSCLC: a network meta-analysis of hypertension and thrombotic risks by Mingming Tan, Chenwei Pu, Zhenzhen Wang, Chengwei Jin

“…Erlotinib had the lowest incidence of hypertension (SUCRA: 91.1%), followed by chemotherapy (88.8%). For thrombotic events, Erlotinib had the lowest risk (SUCRA: 66.1%), while Anlotinib and Cabozantinib had the highest thrombotic risks (SUCRA: 26.9%).ConclusionErlotinib presents the lowest risk for hypertension and thrombotic events, making it a preferred choice for NSCLC patients with cardiovascular concerns.Systematic review registrationhttps://www.crd.york.ac.uk/prospero, identifier CRD42024530770.…”
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Identification of disulfidptosis-related subtypes in gastric cancer and GAMT is a key gene during disulfidptosis by Wenxue Wu, Guoqiang Tao, Zhiqing Chen, Qi Zhou

“…Cluster 2 patients are more sensitive to various chemotherapy drugs and immunotherapy. Mesenchymal cells, especially myCAF, endothelial cells, and smooth muscle cells, have strong disulfidptosis scores. …”
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Establishment and characterization of three gemcitabine-resistant human intrahepatic cholangiocarcinoma cell lines by Jiandong Li, Yanxin Hu, Jiayao Zhang, Weiguang Zhang, Jianhua Yu, Baochun Lu

“…Abstract Intrahepatic cholangiocarcinoma (ICC) is a highly malignant liver tumor associated with a dismal prognosis, largely due to chemotherapy resistance. However, the mechanisms underlying gemcitabine (GEM) resistance in ICC remain poorly understood. …”
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Treatment of primary esophageal lymphomas: A review by Joe El Khoury, Remy Daou, Neal Kim, Josiane Bou Eid, Brandon Imber, Joachim Yahalom, Carla Hajj

“…This literature review provides a comprehensive overview of the use of available treatment options for primary esophageal lymphoma, including surgery, radiotherapy, and chemotherapy. The review also highlights the current knowledge gaps that need to be addressed through further research. …”
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A Rare Association of Autoimmune Hemolytic Anemia with Gastric Adenocarcinoma by Kavita Agrawal, Flores Alfonso

“…The patient was weaned off steroids and paradoxically IgG-mediated autohemolysis was controlled with the initiation of palliative chemotherapy. Our case highlights a rare occurrence of AIHA in association with gastric adenocarcinoma.…”
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Measuring Response to Therapy by Near-Infrared Imaging of Tumors Using a Phosphatidylserine-Targeting Antibody Fragment by Jian Gong, Richard Archer, Michael Brown, Seth Fisher, Connie Chang, Matthew Peacock, Christopher Hughes, Bruce Freimark

“…Phosphatidylserine (PS) is confined to the inner leaflet of the plasma membrane in normal cells but is externalized on tumor vascular endothelial cells (ECs) and tumor cells, and PS exposure is further enhanced in response to radiation and chemotherapy. In the present study, we evaluated the potential of a PS-targeting human F(ab') 2 antibody fragment, PGN650, to detect exposure of PS in tumor-bearing mice. …”
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Malignant Transformation of a Mature Cystic Ovarian Teratoma into Thyroid Carcinoma, Mucinous Adenocarcinoma, and Strumal Carcinoid: A Case Report and Literature Review by Hilary D. Hinshaw, Ashlee L. Smith, Mohamed Mokhtar Desouki, Alexander B. Olawaiye

“…Additionally, extrapolating from data for mucinous adenocarcinomas, consideration could be given to adjuvant chemotherapy after appropriate staging (b). Strumal carcinoid tumors should be treated as tumors of low malignant potential. …”
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Spatial heterogeneity of the hepatocellular carcinoma microenvironment determines the efficacy of immunotherapy by Minni Zhang, Kailin Huang, Qiushi Yin, Xueqin Wu, Mingyue Zhu, Mengsen Li

“…HCC has a specific immune tolerance function because of its unique physiological structure, which limits the efficacy of chemotherapy, radiotherapy, and molecular targeting. …”
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A New Challenging Strategy in the Prevention and Management of Tumor Lysis Syndrome in Patients with Chemo-Sensitive Hematological Malignancies by Ammar ELJack, Mohamad El Abdallah, Kadhim Al-Banaa, Kashif Chaudhry, Faisal Musa

“…It happens frequently in cancers receiving chemotherapy, particularly hematological malignancies. …”
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Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report by Daniela Oliveira, Vanessa Chaves, José Carlos Martins, Carlos Vaz, Miguel Bernardes, Jorge Almeida

“…Despite institution of chemotherapy, the patient succumbed to the malignancy. …”
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Acute Tracheal Obstruction Secondary to Cervical Liposarcoma Metastasis by Haoyu Chen, Song Zhang, Haining Zhou

“…We report a case of a 43‐year‐old man with cervical liposarcoma who, following surgical excision, chemotherapy, and radiation, presented with severe dyspnea and was admitted to our hospital. …”
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Fractional and stochastic modeling of breast cancer progression with real data validation. by Khaled Aldwoah, Hanen Louati, Nedal Eljaneid, Tariq Aljaaidi, Faez Alqarni, AbdelAziz Elsayed

“…Further, we investigate the impact of chemotherapy and its associated cardiotoxicity, illustrating different treatment response scenarios through graphical representations. …”
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Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Liter... by Takunori Ogawa, Jun Miyata, Koichi Fukunaga, Akihiko Kawana, Takashi Inoue

“…As the patient did not respond to the initial treatment with calcitonin, extracellular fluid infusion, and chemotherapy, systemic prednisolone was administered additionally. …”
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MALT-lymphoma of the stomach: clinical presentation, diagnostics and treatment by Ye. V. Ledin, A. P. Seryakov, V. L. Astashov

“…The article stresses therapeutic aspects: correspondence of treatment approach to disease stage, presence of Н. pylori infection, role of eradication and radiation therapy, surgery and chemotherapy. Basing on obtained data, original treatment algorithm was developed, which is proposed to application in clinical practice to provide optimal amount of medical care to the patient.Conclusion. …”
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Double-Expressor Appendiceal Burkitt’s Lymphoma: A Case Report and Literature Review by Osama N. Dukmak, Hamzeh M. I. Abugharbieh, Mohammad Farid Emar, Iman Khamayseh, Salem M. Tos, Rafiq Salhab

“…Histopathological examination of the appendectomy specimen revealed a double-expressor non-Hodgkin diffuse large cell lymphoma with Burkitt’s-like morphology. He was sent for chemotherapy treatment. Conclusion. Only 34 cases of Burkitt’s lymphoma have been reported to present as acute appendicitis. …”
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