Case report: Gastric langerhans cell histiocytosis with BRAF deletion mutation in a child that was misdiagnosed as lymphoma by Zhi Wan, Zhi Wan, Xue Tang, Xue Tang, Ju Gao, Ju Gao, Jing-jing Sun, Jing-jing Sun

“…The patient’s condition rapidly improved after chemotherapy with prednisone and vincristine. This case report focuses on the possibility of gastric LCH in school-aged children and the differential diagnosis of gastric tumors in children.…”
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Maltoma of Thyroid: A Rare Thyroid Tumour by Navisha Latheef, Vijendra Shenoy, M. Panduranga Kamath, Mahesh Chandra Hegde, A. Raghavendra Rao

“…The histologic examination and the immunohistochemistry showed an extra nodal marginal B-cell type maltoma (malt lymphoma). CHOP chemotherapy with rituximab was given. The clinical course has been favourable in the first year of followup, with no evidence of local or systemic recurrence of the disease. …”
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Advances in preclinical and clinical studies of oncolytic virus combination therapy by Wenlong Du, Jintong Na, Liping Zhong, Liping Zhong, Pumin Zhang

“…This paper summarizes the tumor-killing mechanisms of oncolytic viruses, explores their integration with radiotherapy, chemotherapy, immune checkpoint inhibitors, CAR-T, and CAR-NK therapies, and provides an overview of related clinical trials. …”
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Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma by Jinqian Mao, Jin Hu, Yunfei Chen, Yiqing Li, Xiaoqin Run

“…All data were randomly allocated into a training set and a testing set to develop and validate the nomogram model.Results The findings showed that age, sex, grade, tumor size, multiple primary malignant tumors, stage, primary site surgery (PSS), radiotherapy (RT), and chemotherapy (CT) were correlated with prognosis (p < .05). …”
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Large Cell Neuroendocrine Carcinoma of the Bladder with Adenocarcinomatous Component by Rami Halabi, Maher Abdessater, Johnny Boustany, Anthony Kanbar, Halim Akl, Joey El Khoury, Charbel El Hachem, Raghid El Khoury

“…The patient was treated by recurrent tumor resections, chemotherapy, and radiotherapy. No improvement was noted despite close follow-up and adequate treatment. …”
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In Vivo and In Vitro Studies Assessing the Antiviral Efficacy of Double Combinations Against Coxsackievirus B Infection by Adelina Stoyanova, Simeon Galabov, Vadim Makarov, Angel S. Galabov

“…All data obtained prove the potential of the CAA scheme for the development of effective chemotherapy of enterovirus infections.…”
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Development and pan-cancer validation of an epigenetics-based random survival forest model for prognosis prediction and drug response in OS by Chaoyi Yin, Kede Chi, Zhiqing Chen, Shabin Zhuang, Yongsheng Ye, Binshan Zhang, Cailiang Cai

“…Risk stratification analysis revealed distinct therapeutic response patterns, with low-risk groups showing enhanced sensitivity to traditional chemotherapy drugs while high-risk groups responded better to targeted therapies.ConclusionOur epigenetics-based model demonstrates excellent prognostic accuracy (AUC&gt;0.997 in internal validation, 0.832–0.929 in external cohorts) and provides a practical tool for treatment stratification. …”
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Towards the Application of Atorvastatin to Intensify Proapoptotic Potential of Conventional Antileukemic Agents In Vitro by Jolanta D. Żołnierczyk, Arleta Kaźmierczuk, Paweł Hikisz, Barbara Cebula-Obrzut, Ewa Wawrzyniak, Jerzy Z. Błoński, Małgorzata Misiewicz, Paweł Robak, Piotr Smolewski, Zofia M. Kiliańska

“…The usage of atorvastatin together with or followed by the conventional chemotherapy should be considered as therapeutic option for the treatment for this leukemia. …”
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Mantle Cell Lymphoma in the Thyroid: A Rare Presentation by Uzma Mohammad Siddiqui, Sarika N. Rao, Pallavi Kanwar Galera, Nahida Islam, Mira S. Torres

“…Conclusion. Though chemotherapy is the treatment of choice in MCL, a subset of patients with low-grade disease may be observed. …”
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Influence of Febrile Neutropenia Period on Plasma Viscosity at Malignancy by Ibrahim Tek, Selami Kocak Toprak, Efe Hasdemir, Samed Rahatli, Aysegül Yesilkaya

“…Cancer, chemotherapy, and infections all together make changes in blood rheology and may affect the defense mechanisms by changing the thrombocyte function and endothelial cell. …”
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Pseudomyxoma Peritonei Originating from Transverse Colon Mucinous Adenocarcinoma: A Case Report and Literature Review by Yingbo Gong, Xin Wang, Zhi Zhu

“…The abdomen mass increased in the month before treatment. After chemotherapy, the transverse colon mass and ovarian giant cyst were resected and about 2000 mL of gelatinous tumor tissue was removed. …”
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Enhanced tumor self-targeting of lemon-derived extracellular vesicles by embedding homotypic cancer cell membranes for efficient drug delivery by Lu-Yao Yang, Guo-Wu Liang, Bing-Jie Cai, Ke-Min Xu, Yu-Jie Zhao, Xiao-Ting Xie, Yu-Lin Zhang, Chao-Qing Li, Guo-Jun Zhang

“…Herein, a composite nanodrug delivery system by encapsulating the chemotherapy drug DOX is establish to efficiently target breast cancer. …”
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Clinical analysis of different intestinal reconstruction methods after primary cytoreductive surgery combined with rectal resection for advanced ovarian cancer by Huimin Wang, Xiaocen Li, Ying Jiang, Jinxin Chen, Rong Cao, Jingru Zhang

“…The colostomy group had a lower serum albumin level, larger volume of ascites, higher likelihood of multiple intestinal resections and lower likelihood of rectal resection, lower peritoneal cancer index, more intraoperative blood loss, transfusions and infusions, lower likelihood of optimal cytoreductive surgery and shorter interval time to chemotherapy than the other two groups (p &lt; 0.05). …”
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Gut Microbiota Secondary Metabolites: Key Roles in GI Tract Cancers and Infectious Diseases by Eman K. E. Anwer, Muhammad Ajagbe, Moustafa Sherif, Abobaker S. Musaibah, Shuaib Mahmoud, Ali ElBanbi, Anwar Abdelnaser

“…Conversely, these same metabolites hold therapeutic promise, potentially enhancing responses to chemotherapy and immunotherapy and even directly suppressing tumor growth. …”
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Disseminated Cerebrospinal Embryonal Tumor in the Adult by Alessandro Caporlingua, Daniele Armocida, Federico Caporlingua, Gennaro Lapadula, Grazia Maria Elefante, Manila Antonelli, Maurizio Salvati

“…The patient underwent chemotherapy with postoperative adjuvant alternating Vincristine-Doxorubicin-Ifosfamide (VAI) and Ifosfamide-Etoposide (IE). …”
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HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas by M. J. Rutten, F. Dijk, C. D. Savci-Heijink, M. R. Buist, G. G. Kenter, M. J. van de Vijver, E. S. Jordanova

“…In addition, HLA-G expression was associated with longer progression-free survival (P=0.036) and response to chemotherapy (P=0.014). Accordingly, high expression of HLA-G mRNA was associated with prolonged disease-free survival (P=0.037) in 65 corresponding samples. …”
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Urothelial Carcinoma of the Urinary Bladder in Young Adults: Presentation, Clinical behavior and Outcome by Michael Nomikos, Athanasios Pappas, Maria-Emmanouela Kopaka, Stavros Tzoulakis, Ioannis Volonakis, Georgios Stavrakakis, Georgios Avgenakis, Ploutarchos Anezinis

“…Three (9%) patients with invasive disease underwent cystectomy and adjuvant chemotherapy and one developed metastatic disease. Ten (32%) patients recurred during followup with a disease free recurrence rate of 65% the first 2 years after surgery. …”
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Single cell RNA sequencing improves the next generation of approaches to AML treatment: challenges and perspectives by Zahra Khosroabadi, Samaneh Azaryar, Hassan Dianat-Moghadam, Zohreh Amoozgar, Mohammadreza Sharifi

“…Generated data of the transcriptional profile of the AML could even allow the development of cancer vaccines and CAR T-cell therapies while saving valuable time and alleviating dangerous side effects of chemotherapy and HSCT in vivo. However, scRNA-seq applications face various challenges such as a large amount of data for high-dimensional analysis, technical noise, batch effects, and finding small biological patterns, which could be improved in combination with artificial intelligence models.…”
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Long-term Outcome of Vascularized Fibular Bone Graft Reconstruction for Upper Limb Osteosarcoma: A Case Report by Revanth Thiruvarul Selvan, Gutta Charith, Viveksheel Bhatti, Gopinath Menon

“…Materials and methods: This is a case report of a 34-year-old female who underwent left proximal humerus osteosarcoma wide excision and reconstruction with free vascularized fibula graft and chemotherapy 12 years back. During these 12 years, the patient had gradual improvement in her movements in her left upper limb and overall outcome. …”
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A Rare Form of Melanoma Masquerading as a Diabetic Foot Ulcer: A Case Report by Susan Thomas, Yuan-Xiang Meng, Vijaykumar G. Patel, Gregory Strayhorn

“…The treatment included wide margin excision of the lesion with en bloc amputations of 4th and 5th toes, followed by adjuvant chemotherapy. Discussion. The development of ALM may potentially relate to diabetes as a reported higher prevalence of diabetes with ALM patients. …”
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