Adolescent and Young Adult Testicular Germ Cell Tumors: Special Considerations by Amanda F. Saltzman, Nicholas G. Cost

“…Similar to T-GCTs of all ages, surgical excision with orchiectomy is the standard initial step in treatment. Chemotherapy, retroperitoneal lymph node dissection, and targeted treatment of distant metastases make even widely disseminated disease treatable and curable. …”
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Metastatic Squamous Cell Carcinoma of the Anus to the Lung Confirmed with Allelotyping by Rachel Roth, Susan Moffatt-Bruce, Marino E. Leon

“…The patient was treated with palliative chemotherapy instead of additional surgical treatment. …”
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Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses by Christopher Rizzo, David James Camilleri, Alexandra Betts, Andre’ Gatt, Stephen Fava

“…The patient was started on systemic chemotherapy, but her disease progressed with neurological involvement which responded to second-line therapy. …”
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NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance by Shaoyan Shi, Xuehai Ou, Chao Liu, Rui Li, Qianjin Zheng, Leiming Hu

“…It also enhances tumor cell resistance to chemotherapy and radiotherapy by activating anti-apoptotic signaling pathways and exacerbating treatment-induced inflammation. …”
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A review on the potential of Bruton’s tyrosine kinase (Btk) inhibitor – Ibrutinib for treatment of Multiple Myeloma (MM) by Sze-Ting Bong, Lydia Ngiik-Shiew Law, Jodi Woan-Fei Law

“…MM remains as an incurable cancer, but it can be treated through chemotherapy. Nonetheless, research on novel therapies for effective treatment of MM is ongoing and in this case the involvement of Bruton’s tyrosine kinase (Btk) in B-cell malignancies has made it one of the new therapeutic targets. …”
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“Dead Cells Talking”: The Silent Form of Cell Death Is Not so Quiet by Richard Jäger, Howard O. Fearnhead

“…In this time the ideas that apoptosis protects us from tumourigenesis and that cancer chemotherapy works by inducing apoptosis also emerged. …”
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Leiomyosarcoma of the Renal Vein Mimicking a Primitive Renal Cell Carcinoma: Case Report of an Unusual Presentation by Amal Fekkar, Hafsa Elouazzani, Ahmed Jahid, Kaoutar Znati, Fouad Zouaidia, Zakia Bernoussi

“…Standard treatment consists of radical nephrectomy followed by chemotherapy and/or radiotherapy. Because of insufficient histological data and follow-up, the prognosis factors are not well identified. …”
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Multicomponent Nanocomposites for Complex Anticancer Therapy: Effect of Aggregation Processes on Their Efficacy by Nataliya Kutsevol, Yuliia Kuziv, Tetiana Bezugla, Vasyl Chumachenko, Vasyl Chekhun

“…The water-soluble star-like dextran-graft-polyacrylamide copolymer was used as a nanoplatform for the creation of polymer-based multicomponent drug delivery systems for photodynamic and combined (photodynamic+chemotherapy) antitumor therapy. The three-component nanocomposites with incorporated gold nanoparticles and photosensitizer and the four-component ones additionally loaded by Doxorubicin into polymer nanoplatform were studied at 25 and 37°C by transmission electron microscopy and dynamic light scattering. …”
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Treatment of neuropathic pain with repeated low-dose MDMA: a case report by Peter Gasser, Matthias E. Liechti, Friederike Holze

“…A 64-year-old male patient who suffered from traumatic life experiences and neuropathic pain after oncological chemotherapy was treated with medium to high doses of lysergic acid diethylamide (LSD) and high doses and microdoses of methylenedioxymethamphetamine (MDMA). …”
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Epitranscriptomic RNA m6A Modification in Cancer Therapy Resistance: Challenges and Unrealized Opportunities by Mohammad Burhan Uddin, Zhishan Wang, Chengfeng Yang

“…Abstract Significant advances in the development of new cancer therapies have given rise to multiple novel therapeutic options in chemotherapy, radiotherapy, immunotherapy, and targeted therapies. …”
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The role of radiotherapy in small cell lung cancer: a new paradigm for the radiation oncologist by Paolo Borghetti, Sara Ramella, Sara Ramella, Umberto Ricardi

“…Radiotherapy plays a crucial role in this oncological scenario, and there are still many open questions on the correct application of radiotherapy and its integration with chemotherapy and immunotherapy. These issues are of great interest to the oncology community; among these, in particular, there are the choice of optimal fractionation and total dose for thoracic radiotherapy in limited SCLC and its biological implications, the role of prophylactic cranial irradiation and thoracic consolidation in the context of modern treatments with chemoimmunotherapy in extensive SCLC, the role and indications of stereotactic radiotherapy in oligometastatic scenario and finally the complex clinical and multidisciplinary management of SCLC. …”
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Mesenchymal Stem Cells and their Derived Exosomes Promote Malignant Phenotype of Polyploid Non-Small-Cell Lung Cancer Cells through AMPK Signaling Pathway by Lili Wang, Mingyue Ouyang, Sining Xing, Song Zhao, Shuo Liu, Lingyan Sun, Huiying Yu

“…Chemotherapy is an important method for the treatment of non-small-cell lung cancer (NSCLC), but it can lead to side effects and polyploid cancer cells. …”
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Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer by Lixuan Tang, Xiao Yang, Liwen He, Chaogeng Zhu, Qingshan Chen

“…Although traditional treatment methods such as surgery, radiotherapy, and chemotherapy have increased the survival rate of patients, their efficacy remains unsatisfactory owing to the nonspecific distribution of drugs, high toxicity, and drug resistance of tumor tissues. …”
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A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment by Aoling Huang, Haochen Xue, Ting Xie, Lingyan Xiang, Zhengzhuo Chen, Aolong Ma, Honglin Yan, Jingping Yuan

“…Standard treatments include chemotherapy, surgery, endocrine therapy, and targeted therapy. …”
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Ocular adnexal lymphoma – A single-center observational study of survival outcomes by Karuvel Kannan Saraswathi, Pragya Saini, Radhakrishnan Santhi, Veerappan Muthukkaruppan, Ayyasamy Vanniarajan, Usha Kim

“…In addition, 83% of patients were treated with chemotherapy, and with a median follow-up of 38 months, complete remission was achieved in 48% of patients. …”
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A Nonpediatric Extraosseous Ewing Sarcoma of the Pancreas: Differential Diagnosis and Therapeutic Strategies by Binoy Yohannan, Mark Feldman

“…She was diagnosed with extraosseous Ewing sarcoma of the pancreas and underwent multiagent neoadjuvant chemotherapy followed by surgical resection, but subsequent imaging revealed evidence of systemic disease progression. …”
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Addressing the consequences of missing vaccines: A case report of pertussis in a child with acute lymphoblastic leukemia by Diana Marcela Perea Rojas, Indiana Luz Rojas Torres, Luis Enrique Perea Vásquez

“…We report a case of a 3-year-old boy with ALL who developed a Bordetella parapertussis infection during chemotherapy. The child's lack of documented pertussis vaccination underscores critical gaps in primary healthcare and immunization practices. …”
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Ocular Tuberculosis with Multiple Cerebral Abscesses by Saidin Nor-Masniwati, Embong Zunaina, Yaakub Azhany

“…He was treated with antituberculosis chemotherapy for one year which divided into intensive phase for three months and maintenance phase for nine months. …”
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Lymph Node Abscessation Secondary to Neoplasia in Two Dogs by Erin Close, Sarah Lumbrezer-Johnson, Eric Hostnik, Rhonda Burge, Ryan Jennings, Laura Selmic

“…Both dogs underwent surgical extirpation of the lymph nodes and adjuvant chemotherapy protocols. Six weeks postsurgical excision, dog one was euthanized due to quality-of-life concerns. …”
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Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review by Michael Coulter, Jingxuan Liu, Mark Marzouk

“…Although these tumors are not very responsive to chemotherapy or radiation, adjuvant treatment is commonly used when margins are unclear.…”
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