Grisotti flap for central quadrant breast tumours: quick, cosmetic and easy to learn – a case series by Sharma Shivaji, Pao Karan

“…Methods: Seven consecutive patients with centrally located breast tumours were subjected to breast conservation surgery – either upfront or after neoadjuvant chemotherapy – followed by reconstruction with Grisotti flap. …”
Get full text

Stomach Metastasis in a Patient with Prostate Cancer 4 Years after the Initial Diagnosis: A Case Report and a Literature Review by Ahmet Bilici, Mustafa Dikilitas, Ozlem Ton Eryilmaz, Bekir Selim Bagli, Fatih Selcukbiricik

“…Esophagogastroscopy revealed multiple ulcerations in the gastric body and histopathological examination confirmed gastric metastasis that originated from prostate cancer. Chemotherapy could not be given because of patient's refusal. …”
Get full text

Herpes simplex virus-2-associated esophagitis in immunocompetent host by Haider A. Naqvi, Sumanthkumar Bandaru, Adrien L. Janvier, Muhammad Nadeem Yousaf

“…Common risk factors for HE include a history of HIV, AIDS, malignancy, solid organs transplant, use of steroids, immunosuppressant medications, chemotherapy, and radiation therapy [1, 3–7]. An estimated 10–15% of bone marrow transplant patients and up to 20% of AIDS patients may develop HE [8]. …”
Get full text

Overview of hepatocarcinogenesis focusing on cellular origins of liver cancer stem cells: a narrative review by Jong Ryeol Eun

“…As CSCs typically reside in the G0 phase of the cell cycle, they are resistant to conventional chemotherapy. Therefore, to effectively treat HCC, developing therapeutic strategies that target liver CSCs is essential. …”
Get full text

Colon cancer surgery. Five years of experience. by Nicolás Rubio Silveira, Javier López Mayedo, Carlos Echevarría del Risco, Katia García Paneca

“…There was a resect of the tumor in 16 cases and only 2 have died due to the disease . Chemotherapy with 5 fluoruracile was applied to 9 patients, with good results.…”
Get full text

Lymphatic Malformation, Retinoblastoma, or Facial Cleft: Atypical Presentations of PHACE Syndrome by María Fernández-Ibieta, Juan Carlos López-Gutiérrez

“…In the second case, an anomaly of the posterior segment of the eye, not mentioned before in PHACE literature, a retinoblastoma, has been described. Specific chemotherapy avoided enucleation. And, in the third case, the child presented with an unusual midline frontal bone cleft, corresponding to Tessier 14 cleft. …”
Get full text

Mixed Acinar-Neuroendocrine Carcinoma of the Pancreas with Neuroendocrine Predominance by Onyekachi Henry Ogbonna, Marie Carmel Garcon, Kostas N. Syrigos, Muhammad Wasif Saif

“…She underwent surgical resection of the tumor and was offered adjuvant treatment chemotherapy with carboplatin, etoposide, and radiotherapy for positive tumor resection margins. …”
Get full text

Paraneoplastic Autoimmunity Associated with Testicular Myeloid Sarcoma and Chronic Myelomonocytic Leukemia by Jeffrey W. Craig, Richard J. Lin

“…Treatment with both radical orchiectomy and leukemia-directed chemotherapy led to immediate reductions in symptom severity, suggesting that these early symptoms were paraneoplastic in origin. …”
Get full text

Advances in Immunotherapy and Targeted Therapy of Malignant Melanoma by Xue Wang, Shanshan Ma, Shuting Zhu, Liucun Zhu, Wenna Guo

“…Traditional treatments such as surgery, chemotherapy, and radiotherapy are unable to achieve the expected results due to MM’s low sensitivity, high drug resistance, and toxic side effects. …”
Get full text

The Potential Role of Liver Transplantation as a Treatment Option in Colorectal Liver Metastases by Pål-Dag Line, Morten Hagness, Svein Dueland

“…Strict selection criteria have not yet been well defined, but tumor load, response to chemotherapy, pretransplant carcinoembryonic antigen level, and time interval from resection of the primary tumor to transplant are all factors related to outcome. …”
Get full text

Towards Curative Therapy in Burkitt Lymphoma: The Role of Early African Studies in Demonstrating the Value of Combination Therapy and CNS Prophylaxis by Ian Magrath

“…Pioneer investigators explored the value of chemotherapy since surgery and radiation were not effective modalities. …”
Get full text

Traditional Chinese Medicine Protects against Cytokine Production as the Potential Immunosuppressive Agents in Atherosclerosis by Yan Ren, Wei Qiao, Dongliang Fu, Zhiwei Han, Wei Liu, Weijie Ye, Zunjing Liu

“…Accordingly, strategies to inhibit immune activation and impede immune responses towards anti-inflammatory activity are an alternative therapeutic strategy to conventional chemotherapy on cardiocerebrovascular outcomes. Since a number of Chinese medicinal plants have been used traditionally to prevent and treat atherosclerosis, it is reasonable to assume that the plants used for such disease may suppress the immune responses and the resultant inflammation. …”
Get full text

Recent advances of antibody-drug conjugates in treating breast cancer with different HER2 status by Yue Qiu, Yaqin Shi, Zhujun Chao, Xinyu Zhu, Yan Chen, Linlin Lu

“…ADCs combine the specificity of monoclonal antibodies with the cytotoxic effects of chemotherapy, which allows for the targeted delivery of a cytotoxic payload to cancer cells. …”
Get full text

Sintilimab for the treatment of lung adenocarcinoma-induced immune-related hypophysitis: a case report by Ming-xing Wang, Ai-xin Liu, Qing-ming Sun, Wan-hui Dong

“…This report describes a case of a lung cancer patient who, after receiving chemotherapy in combination with the programmed death-1 (PD-1) inhibitor sintilimab, presented with systemic fatigue, alterations in mental and behavioral patterns, somnolence, and symptoms of diabetes insipidus, leading to a diagnosis of grade 4 immune-related hypophysitis. …”
Get full text

Lung Cancer Associated with Neurofibromatosis Type I by Anastasia Oikonomou, Dimitrios Mikroulis, Paraskevi Mintzopoulou, Lawal Lukman, Panos Prassopoulos

“…The patient did not receive systemic chemotherapy or radiotherapy. She was free of disease on 18-month followup.…”
Get full text

Melittin: A Natural Component of Honeybee Venom as a Potential Anti-Cancer Therapy by Niamh Donnellan, Anne M Friel

“…Cancer is a major cause of death worldwide and while chemotherapy is the main approach there are many negative associations in current treatment procedures. …”
Get full text

Benign Multicystic Peritoneal Mesothelioma: A Rare Condition in an Uncommon Gender by Muhammad S. Khurram, Hamadullah Shaikh, Uqba Khan, Jacob Edens, Warda Ibrar, Ameer Hamza, Awais Zaka, Roohi Bano, Tarik Hadid

“…We report a case series of three male patients who were diagnosed with BMPM and were treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).…”
Get full text

Malignant Mesothelioma of the Pericardium: A Report of Two Different Presentations by Pattarapong Makarawate, Narumol Chaosuwannakit, Jarin Chindaprasirt, Piti Ungarreevittaya, Surachat Chaiwiriyakul, Kosin Wirasorn, Chusak Kuptarnond, Kittisak Sawanyawisuth

“…Both patients: may have indirect exposure to asbestos. Despite chemotherapy, both patients died at 2 weeks and 3 months after the diagnosis. …”
Get full text

Review of Small Cell Carcinomas of the Prostate by P. Furtado, M. V. A. Lima, C. Nogueira, M. Franco, F. Tavora

“…Treatment consists mainly of chemotherapy associated with surgery. Radiation therapy is reserved for selected cases. …”
Get full text

Myokines as Possible Therapeutic Targets in Cancer Cachexia by Emilia Manole, Laura C. Ceafalan, Bogdan O. Popescu, Carmen Dumitru, Alexandra E. Bastian

“…This syndrome has a dramatic impact on the patient’s quality of life, and it is also associated with a low response to chemotherapy leading to a decrease in survival. Despite this, cachexia is still underestimated and often untreated. …”
Get full text