An Unusually Short Latent Period of Therapy-Related Myeloid Neoplasm Harboring a Rare MLL-EP300 Rearrangement: Case Report and Literature Review by Reina Takeda, Kazuaki Yokoyama, Seiichiro Kobayashi, Toyotaka Kawamata, Sousuke Nakamura, Tomofusa Fukuyama, Mika Ito, Nozomi Yusa, Eigo Shimizu, Nobuhiro Ohno, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Kaoru Uchimaru, Arinobu Tojo

“…Therapy-related myeloid neoplasm (t-MN) is a late and lethal complication induced by chemotherapy and/or radiation therapy. Hematological malignancy is one of the most common primary diseases in patients with t-MN. …”
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CD7‐targeting pro‐apoptotic extracellular vesicles: A novel approach for T‐cell haematological malignancy therapy by Bei Zhang, Jianqiang Chen, Jiming Chen, Yingying Shen, Yinghu Chen, Shibo Wang, Chengyan Zhang, Yuzhou He, Huajun Feng, Jiaoli Wang, Zhijian Cai

“…Given the challenges of chemotherapy resistance in patients with T‐cell malignancy, we selected cytochrome C (CytC) and Bcl2 siRNA (siBcl2) as therapeutic agents and loaded them into αCD7/EVs (αCD7/EVs/CytC/siBcl2). …”
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Clinical Characteristics of Neuropathic Pain and Its Relationship with Cancer in Different Corporal Areas—A Systematic Review by Fernanda Danés-López, Cristóbal Diaz-Palominos, Anggie Ortiz Domínguez, Alanna Silva Rodriguez, Constanza Astorga, Daniela Martínez-Hernández, Juan Jose Valenzuela-Fuenzalida, Juan Sanchis-Gimeno, Pablo Nova-Baeza, Alejandra Suazo-Santibáñez, Gustavo Oyanedel-Amaro, Mathias Orellana-Donoso, Héctor Gutiérrez Espinoza

“…<b>Background:</b> Neuropathic pain (NP) and cancer are caused by nerve damage due to cancer or treatments such as chemotherapy, radiotherapy, and surgery, with a prevalence that can reach up to 40%. …”
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Anti-NMDAR-Positive Small-Cell Lung Cancer Paraneoplastic Limbic Encephalitis: A Case Report and Literature Review by Raman Sohal, Steven H. Adams, Vishal Phogat, Abha Harish, Carlos Ynigo D. Lopez, Michael P. A. Williams, Kamal K. Khurana, Basel Abuzuaiter, Nia Jagroop, Bhavya Narapureddy

“…The patient’s neurological symptoms showed improvement following chemotherapy. Conclusion. This case highlights the importance of recognizing short-term memory loss as a feature of PLE.…”
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Sequential Docetaxel in ≥7 Cycles Followed by Cabazitaxel Improves Oncological Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer by Seiichi Kato, Manabu Takai, Koji Iinuma, Shota Fujimoto, Masahiro Nakano, Takashi Ishida, Masahiro Uno, Masayoshi Tamaki, Mitsuhiro Taniguchi, Hisao Komeda, Yoshito Takahashi, Takuya Koie

“…However, it is unclear whether switching to second-line chemotherapy or optimal sequencing of cabazitaxel (CBZ) ensures better clinical outcomes. …”
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Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer by Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, Edward Kai-Hua Chow

“…Despite the addition of chemotherapy to radiotherapy to enhance its tumoricidal effects, almost a third of HNC patients suffer from locoregional relapses. …”
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Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre by Zaid Ahmed Shamsi, Vlad Paraoan, Chang Kim, Sarah Raihanah Saifuddin, Thomas D A Cosker, Duncan Whitwell, Christopher L M H Gibbons, Dionisios Stavroulias, Francesco DiChiara

“…Standard practice currently comprises wide surgical excision, often accompanied by adjuvant chemotherapy and/or radiotherapy. This approach necessitates a multidisciplinary team, ideally in specialised cancer centres. …”
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TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…In the stage I group 7.4% received adjuvant chemotherapy and 15.0% received adjuvant radiotherapy. …”
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Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis by Xinyan Hao, Yucheng Tang, Wenjie Xu, Ming Wang, Jiayi Liu, Yongjiang Li, Jun He, Yanjin Peng, Pengcheng Sun, Dehua Liao, Xiongbin Hu, Tiantian Tang, Min Zhou, Ruyue Han, Jiemin Wang, João Conde, Daxiong Xiang, Junyong Wu

“…Abstract Glioblastoma multiforme (GBM) is characterized by pronounced immune escape and resistance to chemotherapy-induced apoptosis. Preliminary investigations revealed a marked overexpression of gasdermin E (GSDME) in GBM. …”
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Early Effects of Bronchoscopic Cryotherapy in Metastatic Non-Small Cell Lung Cancer Patients Receiving Immunotherapy: A Single-Center Prospective Study by Gediminas Vasiliauskas, Evelina Žemaitė, Erika Skrodenienė, Lina Poškienė, Gertrūda Maziliauskienė, Aurimas Mačionis, Skaidrius Miliauskas, Donatas Vajauskas, Marius Žemaitis

“…Patients received up to four cycles of pembrolizumab as monotherapy or in combination with platinum-based chemotherapy. Immune-related adverse events (irAEs), complications, tumor size changes, overall response rate (ORR), and disease control rate (DCR) were evaluated. …”
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Intussusception in a 4-Year-Old Male Due to Burkitt Lymphoma by Raed Al-Taher, Abdallah Alabadla, Salameh Al-Halaseh, Ghasaq Saleh

“…On the pathology report of the resected segment, Burkitt lymphoma was found to be the cause and chemotherapy was initiated. The patient is doing well and is following up every 6 months for 2 years. …”
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Primary Pancreatic Lymphoma Masquerading as Carcinoma by Nasser A. N. Alzerwi

“…PPL was diagnosed. She received chemotherapy with a CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) protocol with rituximab, which she tolerated with no clinical or radiological evidence of recurrence at 1-year follow-up.…”
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Emphysematous osteomyelitis: A rare case report by Siddartha Guru, Navami Guru, Rezhan Hussein

“…She was treated with six weeks of ceftriaxone and metronidazole and then transitioned to oral amoxicillin-clavulanic acid while on chemotherapy.…”
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Primary Malignant Fibrous Histiocytoma: A Rare Case by Anastasios Katsourakis, George Noussios, Iosif Hadjis, Neofitos Evangelou, Efthimios Chatzitheoklitos

“…The patient received adjuvant chemotherapy with Gemcitabine. Two years after the operation, the patient died due to recurrence of the disease. …”
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Using Mathematical Modeling as a Resource in Clinical Trials by Evans K. Afenya

“…An existing model of cancer chemotherapy is reintroduced and placed within current investigative frameworks regarding approaches to treatment optimization. …”
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Surgical management in hepatocellular carcinoma with portal vein tumour thrombosis: is this the end of the road or a chance to expand the criteria for resectability? by Nikolaos Benatatos, Iliana Papadopoulou, Stelios Assimakopoulos, Francesk Mulita, Evangelos Iliopoulos, Stylianos Germanos, Michail Vailas, Christina Kalogeropoulou, Panagiotis Kitrou, Ioannis Maroulis

“…Evolution of novel surgical techniques in liver resection and associated low morbidity and mortality rates in specialized hepatobiliary centres worldwide have been linked with promising results from the adoption of surgical management in these patients, when compared to systemic chemotherapy or arterial chemoembolization management that has traditionally been followed in such cases.…”
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Immune Thrombocytopenia in a Child with T Cell Lymphoblastic Lymphoma by Kayo Tokeji, Sachi Sakaguchi, Tomoko Kurimoto, Junya Fujimura, Toshiaki Shimizu

“…We describe the case of a 13-year-old boy who presented with persistent thrombocytopenia during maintenance chemotherapy with mercaptopurine and methotrexate for T cell lymphoblastic lymphoma. …”
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Cutaneous Erythema at Scar Site of Modified Radical Mastectomy: An Unexpected Manifestation of Recurrent Carcinoma by Awrad Mohammed-Reda Nasralla, Mohammed Abdulirazzaq Al-Duhileb, Ali Jamal-Aldein Arini, Samir Sami Amr

“…She had neoadjuvant chemotherapy, modified radical mastectomy, and radiotherapy less than one year earlier for the treatment of invasive ductal carcinoma. …”
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The Antioxidant Effect of Erythropoietin on Thalassemic Blood Cells by Johnny Amer, Mutaz Dana, Eitan Fibach

“…Because of its stimulating effect on RBC production, erythropoietin (Epo) is used to treat anemia, for example, in patients on dialysis or on chemotherapy. In β-thalassemia, where Epo levels are low relative to the degree of anemia, Epo treatment improves the anemia state. …”
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Exploring the current potential of immunotherapeutic-based treatment approaches for the management of oral cancer: An updated review by Abin V. Geevarghese, R. Gopika

“…The three primary clinical therapies for oral cancer are chemotherapy, radiation, and surgery. However, the primary issues in clinical care are poor therapeutic outcomes and adverse reactions. …”
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