Infiltrating Cardiac Synovial Sarcoma Presenting as Acute Cerebrovascular Accident by Kelechukwu U. Okoro, Matthew D. Roby, David C. Sane, Robert E. Budin

“…The general consensus for treatment is surgical excision and neoadjuvant chemotherapy and radiotherapy. In this report, a case of synovial sarcoma involving the left ventricular outflow tract and aortic valve is presented.…”
Get full text

A management of patients achieving clinical complete response after neoadjuvant therapy and perspectives: on locally advanced rectal cancer by Yu-Xin Liu, Xin-Rong Yang, Lan-Qing Peng, Zhuo-Hong Li

“…Neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision (TME) and selective use of adjuvant chemotherapy is currently considered the standard of care for locally advanced rectal cancer (LARC). …”
Get full text

The Use of Natural Health Products Especially Papaya Leaf Extract and Dandelion Root Extract in Previously Untreated Chronic Myelomonocytic Leukemia by Leena T. Rahmat, Lloyd E. Damon

“…Conventional therapeutic options include hydroxyurea, hypomethylating agents, and systemic chemotherapy, which are all palliative measures and are associated with potential side effects. …”
Get full text

Combined Therapy for Distant Metastasis of Sacral Chordoma by Birol Özkal, Can Yaldız, Peyker Temiz, Cüneyt Temiz

“…Susceptibility to radiotherapy and chemotherapy is controversial in these tumours. The success of surgical treatment affects survival directly. …”
Get full text

Osteogenesis Imperfecta, Pseudoachalasia, and Gastric Cancer by Dilsa Mizrak, Ali Alkan, Batuhan Erdogdu, Gungor Utkan

“…Pathology showed gastric adenocarcinoma unexpectedly. Chemotherapy was given after assessing dihydropyrimidine dehydrogenase (DPD) enzyme activity, which can be deficient in OI patients. …”
Get full text

FOLFOX Induced Takotsubo Cardiomyopathy Treated with Impella Assist Device by Swethika Sundaravel, Abdulah Alrifai, Mohamad Kabach, Waqas Ghumman

“…Chemotherapy induced cardiotoxicity is becoming increasingly prevalent with several new agents being used recently. …”
Get full text

Serum Voriconazole Level Variability in Patients with Hematological Malignancies Receiving Voriconazole Therapy by Lalit Saini, Jack T Seki, Deepali Kumar, Eshetu G Atenafu, David EC Cole, Betty YL Wong, Andrea Božović, Joseph M Brandwein

“…INTRODUCTION: Voriconazole plasma concentrations have been correlated with oral dosing in healthy subjects, but have been poorly characterized in ill patients with hematological malignancies receiving intensive chemotherapy.…”
Get full text

Anti-melanoma activity of green-produced nanosilver-chlorhexidine complex by Nadezhda Antonova Ivanova

“…The findings of this experiment suggest the potential applicability of the invention in the local chemotherapy of skin melanoma in its early or post-operative stage.…”
Get full text

A Rare Case of Histiocytic Sarcoma Secondary to Gastrointestinal Stromal Tumor in the Stomach: Transdifferentiation or Synchronicity? by Jiankun Tong, Jean Luo, Pierre F. Saldinger, William H. Rodgers

“…Here, we report a 68-year-old female who developed histiocytic sarcoma following chemotherapy with imatinib (Gleevec) for gastrointestinal stromal tumor. …”
Get full text

Epithelial-Myoepithelial Carcinoma of the Base of Tongue with Possible Lung Metastases by Michael Y. Chen, Vipul Vyas, Ryan Sommerville

“…The patient declined chemotherapy and radiotherapy to maximise his quality of life and passed away under management from palliative care several months later. …”
Get full text

Advances in allogeneic hematopoietic stem cell transplantation for Langerhans cell histiocytosis in children by Guangqiang Meng, Saran Feng, Yan Wang

“…Although systemic treatments such as chemotherapy and BRAF/MEK inhibitors have improved the cure rate of LCH, disease reactivation rates remain 30%, and eventually some patients progress to relapse-refractory LCH. …”
Get full text

Cardiac Amyloidosis Masquerading as Hypertrophic Obstructive Cardiomyopathy: Co-existence or Coincidence? by Madhu Shukla, Jagdish Chander Mohan

“…The patient is on specific chemotherapy for the past 7 months and is asymptomatic.…”
Get full text

Growing Teratoma Syndrome: A Rare Case Report and Review of the Literature by Nirmala Kampan, Trika Irianta, Arifuddin Djuana, Lim Pei Shan, Mohd Hashim Omar, Ahmad Zailani Hatta Mohd Dali

“…Growing teratoma syndrome is rare and usually it occurs in the younger aged group. The use of chemotherapy following initial surgical resection will yield the diagnosis following tumour enlargement. …”
Get full text

Concurrent B Cell Acute Lymphoblastic Lymphoma/Leukemia and Monoclonal B Cell Lymphocytosis: A Case Report with Extensive Molecular Analysis by Maryam Mehdipour Dalivand, Parastou Tizro, Julie Partain, Anita Aggarwal, Jack Lichy, Francisco Mot Ara, Victor E. Nava

“…After nonstandard chemotherapy, the patient remains in morphologic remission. …”
Get full text

New insights into the mechanisms of the immune microenvironment and immunotherapy in osteosarcoma by Cong Luo, Xingxing Min, Danying Zhang

“…While surgery and chemotherapy have improved survival for localized cases, pulmonary metastasis significantly reduces survival to approximately 20%, highlighting the need for novel treatments. …”
Get full text

The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer by Alan M. Nieder, Murugesan Manoharan

“…Immediate instillation of single dose chemotherapy agents following TUR is highly recommended to reduce the risk of tumor recurrences.…”
Get full text

Recurrent Syncope Associated with Lung Cancer by Dingguo Zhang, Liansheng Wang, Zhijian Yang

“…The treatment of carcinoma by chemotherapy was indeed sufficient for prompt elimination of the syncope symptoms.…”
Get full text

Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature by H. Coop, L. Pettit, C. Boon, P. Ramachandra

“…They also illustrate that single agent chemotherapy, namely, cisplatin, may be used successfully with limited toxicities.…”
Get full text

Modeling of chemo-radiotherapy targeting growing vascular tumors: A continuum-level approach. by Ioannis Lampropoulos, Marina Koutsi, Michail E Kavousanakis

“…Our simulations demonstrate that this synergistic approach integrates the immediate effectiveness of radiation therapy with the enduring tumor-suppressive capabilities of chemotherapy.…”
Get full text

A rare case of vision loss caused by leptomeningeal metastasis of lung adenocarcinoma: a case report and literature review by Zhihua Li, Jian Chu, Wennan Shen, Junnan Chen, Yuemei Dong, Manze Zhang, Nan Zhao, Wei Zhao, Haoran Zha, Ning Wang, Yalin Han, Zhaoxia Li

“…We reviewed the literature and evaluated survival benefits in patients with LM harboring BRAF non-V600E mutations treated with CSF chemotherapy and mitogen-activated extracellular signal-regulated kinase inhibitors.…”
Get full text