Rotationplasty for Unplanned Fixation of Pathological Fracture Distal Femoral Osteosarcoma by Chindanai Hongsaprabhas, Wittavat Chenboonthai, Phoomchai Suvaraksakul, Chris Charoenlap

“…After discussing with the patient for treatment options, rotationplasty was chosen for her definitive treatment after 3 courses of neoadjuvant chemotherapy. All of the contaminated tissues were removed during the surgery. …”
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Utility and clinical significance of endoscopic ultrasound-guided tissue acquisition for diagnosing lymphadenopathies in biliary tract cancer by Katsuhiko Sato, Minoru Shigekawa, Syuhei Yamamoto, Takayuki Matsumae, Yu Sato, Teppei Yoshioka, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara

“…Thirteen of 16 FNA cytology-positive patients who were diagnosed with preoperative regional lymph node metastasis received chemotherapy prior to surgery. All seven FNA cytology-positive patients who were diagnosed with distant metastasis received systemic chemotherapy. …”
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PARP inhibitors in the treatment of Pancreatic Cancer - A Review of literature by Jagoda Niewiadomska, Wiktor Grela, Daria Furtak, Dawid Tulej, Paulina Głogowska, Alicja Dziedzic, Natalia Gniaź, Dominika Marciniuk, Natalia Marko, Aleksandra Górska

“…The primary therapy for these cancers is surgery; chemotherapy, radiation therapy, hormone therapy, or immunotherapy are also used.  …”
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Investigating neutropenic enterocolitis: a systematic review of case reports and clinical insights by Samane Nematolahi, Ali Amanati, Hossein Molavi Vardanjani, Mohammadreza Pourali, Mahnaz Hosseini Bensenjan, Farnoosh Nozari, Mohebat Vali, Seyed Reza Abdipour Mehrian, Seyed Ali Nabavizadeh, Farima Safari

“…Most cases occur in patients with hematological cancers undergoing chemotherapy. Common presentations include abdominal pain, fever, and diarrhea. …”
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RNF138 contributes to cisplatin resistance in nasopharyngeal carcinoma cells by Hangyu Xu, Qing Yin, Linna Fan, Yating Zhao, Biying Song, Qifan Xu, Jie Zhu, Meifen Xu

“…Abstract Resistance to chemotherapy is a significant concern in the treatment of nasopharyngeal carcinoma (NPC), and occurs due to various mechanisms. …”
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Rationale and design of the multicenter, national, randomized, open labeled phase III trial: allogeneic stem cell transplantation as a potential curative treatment for patients wit... by Annemarie Glöckner, Stefan Schönland, Hermann Einsele, Nicolaus Kröger

“…Patients with multiple myeloma who relapse after initial high-dose chemotherapy with autologous stem cells have a median progression free survival up to 2–3 years, depending on risk factors such as previous remission duration. …”
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Metastatic pancreatic cancer now in remission: a case report and literature review by Charles W. Shi, Thomas J. VanderMeer, Anita Pudusseri

“…The patient was started on standard FOLFIRINOX chemotherapy regimen, completed 6 cycles, but stopped Oxaliplatin and Irinotecan due to neuropathy and fatigue, on November 5, 2020, and transitioned to 5-fluorouracil (5-FU) and leucovorin. …”
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Colonic Gastrointestinal Stromal Tumor: A Population-Based Analysis of Incidence and Survival by Zhiqiang Liu, Yan Sun, Yongfeng Li, Jingyuan Zhao, Shihong Wu, Zibo Meng, Heshui Wu

“…Surgery improved the survival rate, while chemotherapy did not.…”
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Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center by Xin Wang, Xiao-juan Yu, Su-xia Wang, Fu-de Zhou, Ming-hui Zhao

“…Regarding follow-up, patients received bortezomib-based or R-CHOP chemotherapy or supportive treatment only. The mean follow-up time was 22 ± 16 months, and the mean eGFR was 63.098 ± 27.439 ml/min/1.73 m2 at the end of follow-up. …”
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Efficacy and safety of anlotinib as maintenance treatment in extensive-stage small cell lung cancer: a single-armed single center retrospective study by Jin Xiong, Lei Xia, Lei Xia, Lei Xia

“…The median PFS was 8.2 months and 5.6 months for patients who received synchronized immunotherapy or chemotherapy. The median OS was 20.1 months and 15.1 months for patients who received synchronized immunotherapy or chemotherapy. …”
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Treatment Sequencing in a Chronic Lymphocytic Leukemia Patient with Central Nervous System Involvement by Filipa Mousinho, Tatiana Mendes, Paula Sousa e Santos, Maria João Acosta, José Pereira, Maria Arroz, Cândido Silva, Ana Paula Azevedo, Rita Oliveira, Martinha Chorão, Fernando Lima

“…Although no standard protocol exists for this condition, intrathecal chemotherapy, combined with systemic chemoimmunotherapy, has been used previously. …”
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Pelvic Radiotherapy in Rectal Cancer Patients With Synchronous Potentially Treatable Liver Metastases by Yayu Huang, Genwen Chen, Xian Zhang, Yang Qian, Jian Wang

“…We divided the 83 patients into two treatment groups: chemoradiotherapy and surgery (CRT + S) and chemotherapy and surgery (C + S). The CRT + S group (n = 40) received pelvic RT, systemic therapy, and liver metastasis treatment. …”
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Barriers to Adherence to Standard of Care in Appalachia: A Qualitative Assessment in Gastrointestinal Cancers by Levy BE, Castle JT, Bardhan R, Dignan M, Bhakta A

“…While recommended as the standard of care, access to adjuvant chemotherapy treatment is limited in this region due to scarce health services and significant social and geographical barriers. …”
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The Effects of Adverse Events and Associated Costs on Value-Based Care for Metastatic Pancreatic Ductal Adenocarcinoma by Prachi Bhatt, Jared Hirsch, Paul Cockrum, George Kim, Gabriela Dieguez

“…**Conclusions:** Irrespective of drug cost, chemotherapy leading to a significant increase in AEs is associated with higher TCOC.…”
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Extracellular matrix shapes cancer stem cell behavior in breast cancer: a mini review by Lei Li, Lei Li, Yidan Tang, Ling Qiu, Ling Qiu, Zhengrui Li, Ruo Wang, Ruo Wang

“…Even more irritating is the fact that patients with cancers frequently relapse after conventional chemotherapy and radiotherapy, leading to additional suffering. …”
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Insights into the molecular mechanisms and nanoparticle-based therapies for gastric cancer: A review by Smarika Chauhan, Eswar Marcharla, Sneha Hariharan, Saranya Vinayagam, Thanigaivel Sundaram, Priya SD, Swamynathan Ganesan, Maximilian Lackner

“…They also boost therapy outcomes by overcoming chemotherapy resistance and enabling co-delivery of multiple drugs. …”
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Model systems of human immunodef iciency virus (HIV-1) for in vitro eff icacy assessment of candidate vaccines and drugs against HIV-1 by N. B. Rudometova, D. N. Shcherbakov, A. P. Rudometov, A. A. Ilyichev, L. I. Karpenko

“…Selecting an adequate tool for quick and accurate in vitro eff icacy assessment is the key aspect for eff icacy assessment of vaccines and chemotherapy drugs. The classical method of virology, which makes it possible to evaluate the neutralizing activity of the sera of animals immunized with experimental vaccines and the eff icacy of chemotherapy agents is the method of neutralization using viral isolates and infectious molecular clones, i. e. infectious viral particles obtained via cell transfection with a plasmid vector including the full-length HIV-1 genome coding structural, regulatory, and accessory proteins of the virus required for the cultivation of replication-competent viral particles in cell culture. …”
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Real-World Treatment Patterns in Men with Castration- Resistant Prostate Cancer Receiving Docetaxel by Keith L. Davis, Benjamin Gutierrez, Teresa Zyczynski, James A. Kaye

“…**Conclusions:** Concordant with guidelines, docetaxel and prednisone was the preferred first-line chemotherapy regimen in CRPC patients reviewed for this study. …”
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Characteristics and outcomes of secondary acute lymphoblastic leukemia (sALL) after multiple myeloma (MM): SEER data analysis in a single-center institution by Jing Jia, Jiahui Yin, Chuanying Geng, Aijun Liu

“…Younger patients with MM and those who received chemotherapy were at a higher risk of developing sALL. …”
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Pediatric pancreatic acinar cell carcinoma with a non-canonical BRAF-KMT2C fusion and a classic SND1-BRAF fusion: a case report and literature review by Yaqin Wang, Jiasi Zhang, Dimin Nie, Ai Zhang, Qun Hu, Aiguo Liu

“…The patient underwent surgical resection through a Whipple operation followed by six cycles of mFOLIRINOX chemotherapy and radiation therapy, achieving a favorable outcome up to now. …”
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