Comparison of the Efficacy and Safety of PD‐1/PD‐L1 Inhibitors in the Treatment of Small Cell Lung Cancer by Qichen Zhang, Xiaojuan Han, Jiayi Liu, Hui Qiao

“…Conclusion Immunotherapy combined with chemotherapy offers significant benefits for advanced SCLC patients, irrespective of the type of inhibitor used. …”
Get full text

Biological Characteristics and Medical Treatment of Breast Cancer in Young Women—A Featured Population: Results from the NORA Study by P. Pronzato, G. Mustacchi, A. De Matteis, F. Di Costanzo, E. Rulli, I. Floriani, M. E. Cazzaniga

“…At univariate analysis, ER-ve status, chemotherapy and age resulted as the only statistically significant variables (HR=2.02, 𝑃=.004, and >40 versus ≤40, 𝑃<.0001, resp.). …”
Get full text

Utilization of Oncotype DX in an Inner City Population: Race or Place? by Amber A. Guth, Susan Fineberg, Kezhen Fei, Rebeca Franco, Nina A. Bickell

“…Oncotype DX, a 21-gene-array analysis, can guide chemotherapy treatment decisions for women with ER+ tumors. …”
Get full text

γδ T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Discussion of Two Pediatric Cases and Its Distinction from Other Mature γδ T-Cell Malignancies by Eric X. Wei, Vasiliki Leventaki, John K. Choi, Susana C. Raimondi, Elizabeth M. Azzato, Sheila A. Shurtleff, Menchu G. Ong, Diana M. Veillon, James D. Cotelingam, Rodney E. Shackelford

“…She responded to the chemotherapy protocol poorly and had persistent diseases. …”
Get full text

Does stapled colorectal anastomosis in anterior resection always guarantee restoration of intestinal continuity? by P. V. Tsarkov, A. Yu. Kravchenko, I. A. Tulina, P. B. Tsugulya

“…When sphincter-sparing operations are performed for all stages of rectal cancer the most essential risk factors of non-closure of stoma were progression of disease and chemotherapy treatment and patient death related to it, and patient’s death.…”
Get full text

Osteoprotegerin as an Emerging Biomarker of Carotid Artery Stenosis? A Scoping Review with Meta-Analysis by Jerzy Chudek, Marta Pośpiech, Anna Chudek, Michał Holecki, Monika Puzianowska-Kuźnicka

Get full text

Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pil... by Gerhard Schmalz, Lulzim Tulani, Rilana Busjan, Rainer Haak, Tanja Kottmann, Lorenz Trümper, Justin Hasenkamp, Dirk Ziebolz

“…This retrospective pilot study aimed to detect whether remaining dental/periodontal treatment need and periodontal inflammation after dental clearance would be associated with the initial therapy outcome of adult patients with acute leukemia undergoing induction chemotherapy. Different parameters were assessed from the patients’ records: initial blood parameters, blood parameters during initial chemotherapy, leukemia/therapy related complaints, duration of fever, microbiological findings (blood and urine), as well as patients’ survival. …”
Get full text

Expression and clinical significance of disulfidptosis-related LncRNA in gastric cancer by CHU Yudan, SUN Haidong, CUI Ran, ZHENG Hong

“…Differential gene analysis, functional enrichment and the correlation between chemotherapy efficacy in high- and low-risk groups were analyzed. …”
Get full text

Role of Hyperbaric Oxygen Therapy in Prostate Tumor Microenvironment and Cancer Stem Cell Niche by Pranathi Konda, Merrel Holley, Vinoth Kumar Lakshmanan

“…Additionally, it may enhance the effectiveness of radical prostatectomy and chemotherapy by synchronizing cell cycles. Therefore, the current review highlights the key aspects of HBOT in prostate cancer therapy particularly their role addressing late radiation tissue injury (LRTI) and tumor hypoxia. …”
Get full text

Dual Role of Bacteria in Carcinoma: Stimulation and Inhibition by Suad A Al-Hilu, Wisam H Al-Shujairi

“…Bacterial therapies, whether used alone or combination with chemotherapy, give a positive effect to treat multiple conditions of cancer. …”
Get full text

Gastrointestinal side effects in hepatocellular carcinoma patients receiving transarterial chemoembolization: a meta-analysis of 81 studies and 9495 patients by Nathalie Arendt, Maria Kopsida, Jaafar Khaled, Markus Sjöblom, Femke Heindryckx

“…Background: Transarterial chemoembolization (TACE) is a widely used treatment for hepatocellular carcinoma (HCC), combining targeted chemotherapy and embolization. While effective, TACE can be associated with significant gastrointestinal (GI) side effects, impacting a patient’s quality of life. …”
Get full text

Beta-Blockers for Primary Prevention of Anthracycline-Induced Cardiac Toxicity: An Updated Meta-Analysis of Randomized Clinical Trials by Armin Attar, Arman Karimi Behnagh, Mehrasa Hosseini, Foad Amanollahi, Paria Shafiekhani, Ali Kabir

“…Cardiotoxicity is a well-recognized complication of chemotherapy with Anthracyclines. However, results from trials evaluating beta-blockers for prevention are controversial. …”
Get full text

ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance? by Li Pang, Beverly Word, Joshua Xu, Honggang Wang, George Hammons, Shiew-Mei Huang, Beverly Lyn-Cook

“…Genetic polymorphisms in ABC (ATP-binding cassette) transporter genes are associated with differential responses to chemotherapy in various cancers including pancreatic cancer. …”
Get full text

EGFR-TKIs or EGFR-TKIs combination treatments for untreated advanced EGFR-mutated NSCLC: a network meta-analysis by Ao Liu, Xiaoming Wang, Lian Wang, Han Zhuang, Liubo Xiong, Xiao Gan, Qian Wang, Guanyu Tao

“…Conclusion These results reveal that osimertinib plus chemotherapy and lazertinib plus amivantamab are superior first-line options for patients with advanced EGFR-mutated NSCLC. …”
Get full text

Metastatic Malignant Ectomesenchymoma Initially Presenting as a Pelvic Mass: Report of a Case and Review of Literature by A. Nael, P. Siaghani, W. W. Wu, K. Nael, Lisa Shane, S. G. Romansky

“…The patient received national protocol chemotherapy against rhabdomyosarcoma with good response and presented with a cerebellar mass 21 months later. …”
Get full text

Cyclooxygenase 2 (COX2) and Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Are Stage-Dependent Prognostic Markers of Malignant Melanoma by Stefanie Meyer, Thomas Vogt, Michael Landthaler, Anna Berand, Albrecht Reichle, Frauke Bataille, Andreas H. Marx, Anne Menz, Arndt Hartmann, Leoni A. Kunz-Schughart, Peter J. Wild

“…Patients with PPARG-positive metastases and biomodulatory metronomic chemotherapy alone or combined with COX2/PPARG-targeting showed a significantly prolonged progression-free survival. …”
Get full text

Klinefelter syndrome diagnosed at autopsy and small-cell lung carcinoma by Haruyasu Sakuranaka, Ryoma Tanaka, Yuji Yamakawa, Shiho Yamada, Komei Igei, Yasuo Asai

“…He was diagnosed with small-cell lung carcinoma. Chemotherapy was administered, but the disease progressed, eventually leading to death. …”
Get full text

Indirect Comparison Showed Survival Benefit from Adjuvant Chemoradiotherapy in Completely Resected Gastric Cancer with D2 Lymphadenectomy by Qiong Yang, Ying Wei, Yan-Xian Chen, Si-Wei Zhou, Zhi-Min Jiang, De-Rong Xie

“…Three trials compared adjuvant chemoradiotherapy with adjuvant chemotherapy, and 4 trials compared adjuvant chemotherapy with observation. …”
Get full text

Malignant Peripheral Nerve Sheath Tumors in Children with Neurofibromatosis Type 1 by Apostolos Pourtsidis, Dimitrios Doganis, Margarita Baka, Despina Bouhoutsou, Maria Varvoutsi, Maria Synodinou, Panagiota Giamarelou, Helen Kosmidis

“…Wide excision of the tumor and radiotherapy were applied to all and adjuvant chemotherapy was given to three of them after the disease was progressed. …”
Get full text

Implant failure of the Compress prosthesis: a case report by Hiroshi Koike, Kunihiro Ikuta, Hiroshi Urakawa, Tomohisa Sakai, Takeo Fujito, Yoshihiro Nishida, Shiro Imagama

“…Case presentation Case 1 describes a 36 year-old Japanese man who underwent extraarticular tumor resection, Compress arthroplasty, and reconstruction with a gastrocnemius flap after preoperative chemotherapy for a secondary malignant giant cell tumor in the right distal femur. …”
Get full text