RSL3 induces ferroptosis by activating the NF-κB signalling pathway to enhance the chemosensitivity of triple-negative breast cancer cells to paclitaxel by Jialin Yuan, Cong Liu, Chengwei Jiang, Ning Liu, Zhaoying Yang, Hua Xing

“…Abstract Chemotherapy resistance in triple-negative breast cancer (TNBC) leads to poor therapeutic effects and a poor prognosis. …”
Get full text

Pulmonary enteric adenocarcinoma with progression disease after second - line therapy: a case report by Ya Guo, Bin Zhang, Heng Zhang, Yunbin Gao, Haibo Zhao, Pei Jiang, Qing-Qing Yu

“…The results suggest that standard first-line therapies (immunotherapy plus chemotherapy) and colorectal cancer regimens may have a relatively limited impact on survival in KRAS-driver positive advanced PEAC.…”
Get full text

Long-term cardiac MRI follow up of MANTICORE (Multidisciplinary Approach to Novel Therapies in Cardio-Oncology REsearch) by Dina Labib, Mark Haykowsky, Emer Sonnex, John R. Mackey, Richard B. Thompson, D. Ian Paterson, Edith Pituskin

“…Abstract Background This study investigates the long-term cardiac effects of trastuzumab-based chemotherapy in early breast cancer (EBC) survivors. …”
Get full text

Impact of Cardiac Computed Tomographic Angiography Findings on Planning of Cancer Therapy in Patients with Concomitant Structural Heart Disease by Iyad N. Daher, Jose Banchs, Syed Wamique Yusuf, Elie Mouhayar, Jean-Bernard Durand, Gregory Gladish

“…Exclusion of underlying coronary artery disease (CAD) is essential in the diagnosis of chemotherapy-induced cardiomyopathy. Presence and severity of CAD can also impact the choice of therapy in cancer patients. …”
Get full text

Anticancer Drugs Induced Severe Adverse Cutaneous Drug Reactions: An Updated Review on the Risks Associated with Anticancer Targeted Therapy or Immunotherapies by Chau Yee Ng, Chun-Bing Chen, Ming-Ying Wu, Jennifer Wu, Chih-Hsun Yang, Rosaline Chung-Yee Hui, Ya-Ching Chang, Chun-Wei Lu

“…In this article, we have reviewed published articles from 1950 to August 2017 for SJS/TEN associated with anticancer drugs, including chemotherapy, targeted therapy, and immunotherapy. We aimed to provide an overview of SJS/TEN associated with anticancer drugs to increase clinician recognition and accelerate future studies on the pathomechanism and managements.…”
Get full text

The impact of facial disfigurement and self-image anxiety on the quality of life of head and neck cancer patients by Saanjli Bhandari, Ravindra Singh, Sanya Mehndiratta, Mansha Dadhich

“…Head and neck cancer patients undergo surgery and chemotherapy which could lead to changes in their facial appearance as well as voice and speech, resulting in self-image anxiety. …”
Get full text

Utilisation of Cryopreserved Gametes in Cancer Patients who Underwent Fertility Preservation by Devika Gunasheela, N. Ashwini, Yoshita Saneja, D Deepthi

“…Background: Cancer treatments such as chemotherapy and radiotherapy often compromise fertility by damaging gonadal function, creating a critical need for fertility preservation options. …”
Get full text

Successful Use of a Multidisciplinary Approach to Treat a Perforated Duodenal Malignant Lymphoma in an Elderly Patient by Tomoko Takagishi, Yuta Niimi, Goshi Matsuki, Shinta Nagano, Junsuke Hinami, Masaaki Kajiwara, Kiyoshi Kaneko, Yoshihiro Kubota, Osamu Nakai

“…Thereafter, less intensive chemotherapy (two cycles each of R-mini-CHP, CHP, and R-CHOP) was administered, which led to significant improvement upon assessment by PET-CT. …”
Get full text

Isolated central nervous system relapse in blast crisis of chronic myeloid leukemia: a case report by Hari Priya Raghvan, Caroline Ho Siew Ling, Wee Shiang Yui, Boo Yang Liang, Ehram Jamian, Indhira Subbiah

“…A 46-year-old female with underlying CML in lymphoid blast crisis, previously treated with chemotherapy and tyrosine kinase inhibitors, presented with visual disturbances. …”
Get full text

Survival and prognostic factors among different types of liposarcomas based on SEER database by Jiaqi Zhao, WenLi Du, XiaoLiang Tao, AiAi Li, Yi Li, Shuai Zhang

“…The prognosis for different subtypes of liposarcoma and the associated factors such as age, tumor stage, intervention, gender, tumor grade, location, size, chemotherapy and radiotherapy, were retrieved from the database. …”
Get full text

Dramatic response of advanced pulmonary sarcomatoid carcinoma to tislelizumab combined with anlotinib: a case report by Ranran Li, Xiliang Di, Yuan Li, Hao Li, Chonghua Liu

“…Pulmonary sarcomatoid carcinoma (PSC) is a scarce pathologic type of lung cancer of non-small cell lung cancer (NSCLC) that exhibits resistance to conventional chemotherapy and radiotherapy, resulting in a poor prognosis. …”
Get full text

Clinicopathological Characteristics, Treatment, and Prognosis of 21 Patients with Primary Gastric Squamous Cell Carcinoma by Yang Chen, Hong Zhu, Feng Xu, Yidan Cao, Xingting Gu, Yuming Wan, Hongfeng Gou

“…Probably due to limited number of cases, no significant difference in median survival time was observed between the surgery alone group and the surgery plus adjuvant therapy group (46 versus 51 months, P=0.310). A standard chemotherapy regimen for this disease has not yet been established; the choice of its chemotherapy regimens tends to follow the principle of the treatment of gastric adenocarcinoma or esophageal cancer. …”
Get full text

Synthesis and Characterization of 5-Fluoroacil Loaded Calcium Carbonate Nanoparticles for Targeted Cancer Therapy by Kshidan Marim Abdullah Salem, Mohamed Ahmed Ibrahim, Kim Wei Chan, Md Zuki Abu Bakar, Noorjahan Banu Alitheen, Mohammed Alsubbi, Ahmad Faizal Abdull Razis, Norsharina Ismail

“…<img src=" https://s3.amazonaws.com/production.scholastica/article/127799/large/prnano_1622024ga.jpg?1736142025"> Chemotherapy is often limited by its systemic toxicity and lack of specificity, necessitating the development of targeted drug delivery systems that can enhance therapeutic efficacy while minimizing adverse effects. …”
Get full text

Establishment of a Risk Prediction Model for Pulmonary Infection in Patients with Advanced Cancer by Liangliang Yang, Xiaolong Xu, Qingquan Liu

“…Demographics, whether the primary cancer was lung cancer, lung metastasis, the pathological classification of lung cancer patients, the number of metastases, history of surgery, history of chemotherapy, history of radiotherapy, history of central venous catheterization, history of hypertension, diabetes, and whether with myelosuppression were recorded. …”
Get full text

Impact of glycolysis enzymes and metabolites in regulating DNA damage repair in tumorigenesis and therapy by Fengyao Sun, Wen Li, Ruihang Du, Mingchan Liu, Yi Cheng, Jianxing Ma, Siyuan Yan

“…Moreover, considering the significant roles of glycolysis and DDR in tumor development and radio-chemotherapy resistance, the present review discusses effective direct or indirect therapeutic strategies targeted to glycolysis and DDR.…”
Get full text

A Novel Use of Early Radiation Therapy in the Treatment of Hyperbilirubinemia in a Patient with Primary Hepatic Lymphoma and Chronic Hepatitis C by Venkata S. Tammana, Rehana Begum, Patricia Oneal, Hemamalini Karpurapu, Amruta Muley, Sri Lakshmi Hyndavi Yeruva, Jacquelyn Dunmore-Griffith, Eyasu Mekonen, Nabhani Hasan

“…The liver biopsy was consistent with diffuse large B cell lymphoma (DLBCL). Conventional chemotherapy was avoided initially because of hyperbilirubinemia. …”
Get full text

Recent trends and therapeutic potential of phytoceutical‐based nanoparticle delivery systems in mitigating non‐small cell lung cancer by Adam Haysom‐McDowell, Keshav Raj Paudel, Stewart Yeung, Sofia Kokkinis, Tammam El Sherkawi, Dinesh Kumar Chellappan, Jon Adams, Kamal Dua, Gabriele De Rubis

“…Standard treatments including chemotherapy and radiotherapy present multiple adverse effects. …”
Get full text

Male Breast Cancer Originating in an Accessory Mammary Gland in the Axilla: A Case Report by Jun Yamamura, Norikazu Masuda, Yoshinori Kodama, Hiroyuki Yasojima, Makiko Mizutani, Keiko Kuriyama, Masayuki Mano, Shoji Nakamori, Mitsugu Sekimoto

“…This unusual case shows that neoadjuvant chemotherapy is an effective and tolerated therapy for advanced accessory breast cancer in the axilla.…”
Get full text

Tacrolimus and mycophenolate mofetil in corticosteroid-resistant hepatitis secondary to tislelizumab: a case report by Chang Jiang, Shanxian Guo

“…Due to persistent liver dysfunction, the patient failed to receive second-line chemotherapy and ultimately passed away due to disease progression. …”
Get full text

Steroid-Resistant Extranodal Rosai-Dorfman Disease of Cheek Mass and Ptosis Treated with Radiation Therapy by Ahmed Marzouk Maklad, Yasser Bayoumi, Mutahir Tunio, Wafaa AlShakweer, Mashooque A. Dahar, Shomaila A. Akbar

“…Treatment consists of surgery, steroids, chemotherapy, and radiation therapy.…”
Get full text