Primary Yolk Sac Tumor of the Liver: A Rare Cause of Bile Duct Obstruction by Sahil M. Patel, Kenneth M. Sigman, Mohannad F. Dugum

“…He was then started on a curative-intent chemotherapy regimen of bleomycin, etoposide, and cisplatin. …”
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Sigmoid Carcinoma in an Inguinal Hernia: A Blessing in Disguise? by P. B. Salemans, G. F. Vles, S. A. F. Fransen, R. M. Smeenk

“…In most cases the goal of treatment is oncological resection followed by adjuvant chemotherapy in order to optimize the survival. In this case report we present a 93-year-old patient with a sigmoid carcinoma inside an irreducible inguinal hernia, which was diagnosed prior to surgery. …”
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Pneumothorax during Alectinib Treatment for a Uterine Inflammatory Myofibroblastic Tumor with Lung Metastasis by Chang-Ting Lin, Chen-Hsuan Wu, Hsuan-Ying Huang, Chien-Ting Liu

“…After the failure of doxorubicin-based chemotherapy, revised pathology from a palliative hysterectomy revealed an IMT with ALK gene rearrangement. …”
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A Case Report of Embryonal Botryoid Rhabdomyosarcoma of the Uterine Cervix in a 26- Year-Old Woman by Gunel Ziyadova, Altan Kavuncuoglu, Gonca Ozten, Zafer Selcuk Tuncer

“…The patient is considered group 1A in Intergroup RMS Working Group V (IRSG) criteria and the treatment plan continued with adjuvant vincristine, actinomycin D, cyclophosphamide chemotherapy. In the case of cervical polyps in the fertile age, the specimen must be carefully and histologically examined to rule out genital rabdomyosarcoma. …”
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Role of enteroscopy in diagnostics of tumors and preneoplastic diseases of the small intestine by Ye. V. Ivanova, Ye. D. Fedorov, O. I. Yudin, M. Ye. Timofeyev, P. L. Chernyakevich, D. A. Kuznetsov

“…The methods of videocapsular and balloon enteroscopy which have appeared in 2001 allow to estimate macroscopic appearance of tumor more clearly, to determine its character and location, to carry out biopsy, to obtain the proof for chemotherapy prescription, to remove tumor endoscopically or determine indications for elective surgery.Conclusion. …”
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Primary Mucinous Adenocarcinoma of the Urinary Bladder with Signet-Ring Cells: Description of an Uncommon Case and Critical Points in Its Management by Fabrizio Di Maida, Giuliano Amorim Aita, Daniele Amorim Aita

“…We present an uncommon case of mucinous adenocarcinoma of the bladder (MAB) with signet-ring cells extensively infiltrating prostate gland and pelvic/retroperitoneal lymph node stations and not responsive to usual systemic chemotherapy regimens. This case highlights the important features of MAB including the pattern of tumor spread, the tendency for initial misdiagnosis, and the importance of immunohistochemical study in order to define its primary origin from the bladder and choose the most appropriate treatment since the beginning.…”
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Open Questions in the Management of Nodular Lymphocyte Predominant Hodgkin Lymphoma by Marguerite Tyran, Laurence Gonzague, Reda Bouabdallah, Michel Resbeut

“…The new fields reductions proposed for classical Hodgkin lymphoma cannot be applied to early stages Nodular Lymphocyte Predominant Hodgkin lymphomas which are usually treated with radiation therapy without systemic chemotherapy.…”
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Bacteria--phagocyte dynamics,axiomatic modelling and mass-action kinetics by Roy Malka, Vered Rom-Kedar

“…Finally, combining this model with a model of neutrophildynamics in the blood after chemotherapy treatments we obtain new insights regarding the development of infections under neutropenic conditions.…”
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Primary Synovial Sarcoma of the Scrotum by Nourah Al-Oudah, Sara Alanazi, Sarah Saad Alotaibi, Nayef Alzahrani

“…A year later, the patient developed liver, vertebrae, and lung metastasis, which was treated with systemic chemotherapy. Treatment failed to improve the hepatic lesion that was then resected, while the spine and lung lesions were followed by radiotherapy. …”
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Chylothorax from Bilateral Primary Burkitt’s Lymphoma of the Ovaries: A Case Report by A. C. Etonyeaku, O. O. Akinsanya, O. Ariyibi, A. J. Aiyeyemi

“…Disease was advanced at presentation and complicated with both chylothorax and chylous ascites. Response to chemotherapy though dramatic was short lived. This underscores the need for high index of suspicion amongst clinicians. …”
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Revolution in cancer treatment methods: Perspective review of factors affecting the final results of nanoparticles used in magnetic fluid hyperthermia by P. Rastgoo Oskoui, M. Rezvani

“…Magnetic fluid hyperthermia can be used alone or in combination with other conventional therapeutic methods such as chemotherapy, radiotherapy, etc. In order to accurately control the temperature of cancerous tissue and prevent cell necrosis, it is necessary to identify and optimize the factors affecting the magnetic losses of nanoparticles. …”
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Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery by Stephan Klumpp, Lydia M. Jorge, Mohammed Ali Aziz-Sultan

“…Since its recent introduction, superselective ophthalmic artery injection of chemotherapy with melphalan has significantly reduced the need for enucleation in patients with advanced disease and also shown to have minimal adverse effects on visual acuity as compared to the conventional therapy. …”
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Neoadjuvant Immunotherapy and De-escalation of Surgery in Locally Advanced Breast Implant-associated Anaplastic Large Cell Lymphoma by Marzia Salgarello, Jaroslaw Krupa, Rebecca Allchin, Simon Pilgrim, Fiona Miall, Arianna Di Napoli, Maurizio Martelli, Giulio Tarantino

“…The first case was a 52-year-old patient with a left breast mass-like stage III disease who underwent combined targeted immunotherapy and chemotherapy (brentuximab vedotin [BV]–cyclophosphamide, doxorubicin, prednisone [CHP]). …”
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Comparison of Efficacy and Safety of First-Line Treatment Options for Unresectable Stage III Non-Small Cell Lung Cancer: A Retrospective Analysis by Luqing Zhao, Zhiting Zhao, Xiaoqi Yan, Fei Wu, Ning Sun, Renhong Guo, Shaorong Yu, Xiao Hu, Jifeng Feng

“…In the nonradiotherapy group, the DCR and mPFS were higher in the chemotherapy plus immunotherapy subgroup than in the chemotherapy subgroup, with increased toxicity at any grade (DCR: 93.67% vs. 67.86%, p < 0.001; mPFS: 13.53 vs. 5.07 months, p < 0.001; and 68.35% vs. 41.67%, p = 0.001). …”
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Nomogram model and risk score predicting overall survival and guiding clinical decision in patients with Hodgkin’s lymphoma: an observational study using SEER population-based data... by Yue Yang, Shang Li, Xiao Zhu, Yi Kong, Mingtao Zhang, Xiangping Liang, Zherui Zhang, Shuzhen Tan, Yingqi Li, Yueyuan Zhong, Yingqi Shao, Jiayi Xu, Zesong Li

“…We discovered that Derived American Joint Committee on Cancer (AJCC) Stage Group, lymphoma subtype, radiotherapy and chemotherapy were four independent risk factors affecting the prognosis of HL patients. …”
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An Unusually Short Latent Period of Therapy-Related Myeloid Neoplasm Harboring a Rare MLL-EP300 Rearrangement: Case Report and Literature Review by Reina Takeda, Kazuaki Yokoyama, Seiichiro Kobayashi, Toyotaka Kawamata, Sousuke Nakamura, Tomofusa Fukuyama, Mika Ito, Nozomi Yusa, Eigo Shimizu, Nobuhiro Ohno, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Kaoru Uchimaru, Arinobu Tojo

“…Therapy-related myeloid neoplasm (t-MN) is a late and lethal complication induced by chemotherapy and/or radiation therapy. Hematological malignancy is one of the most common primary diseases in patients with t-MN. …”
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Anti-NMDAR-Positive Small-Cell Lung Cancer Paraneoplastic Limbic Encephalitis: A Case Report and Literature Review by Raman Sohal, Steven H. Adams, Vishal Phogat, Abha Harish, Carlos Ynigo D. Lopez, Michael P. A. Williams, Kamal K. Khurana, Basel Abuzuaiter, Nia Jagroop, Bhavya Narapureddy

“…The patient’s neurological symptoms showed improvement following chemotherapy. Conclusion. This case highlights the importance of recognizing short-term memory loss as a feature of PLE.…”
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Sequential Docetaxel in ≥7 Cycles Followed by Cabazitaxel Improves Oncological Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer by Seiichi Kato, Manabu Takai, Koji Iinuma, Shota Fujimoto, Masahiro Nakano, Takashi Ishida, Masahiro Uno, Masayoshi Tamaki, Mitsuhiro Taniguchi, Hisao Komeda, Yoshito Takahashi, Takuya Koie

“…However, it is unclear whether switching to second-line chemotherapy or optimal sequencing of cabazitaxel (CBZ) ensures better clinical outcomes. …”
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Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer by Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, Edward Kai-Hua Chow

“…Despite the addition of chemotherapy to radiotherapy to enhance its tumoricidal effects, almost a third of HNC patients suffer from locoregional relapses. …”
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Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre by Zaid Ahmed Shamsi, Vlad Paraoan, Chang Kim, Sarah Raihanah Saifuddin, Thomas D A Cosker, Duncan Whitwell, Christopher L M H Gibbons, Dionisios Stavroulias, Francesco DiChiara

“…Standard practice currently comprises wide surgical excision, often accompanied by adjuvant chemotherapy and/or radiotherapy. This approach necessitates a multidisciplinary team, ideally in specialised cancer centres. …”
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