Clinical Profile of Unilateral Proptosis in a Tertiary Care Centre by Susan Dsouza, Pooja Kandula, Gurudutt Kamath, Manjunath Kamath

“…Most of them were treated medically (13 cases, i.e., 52%) and the rest by surgery with a combination of radiotherapy/chemotherapy (12 cases, i.e., 48%).…”
Get full text

Primary Synovial Sarcoma of Kidney: A Rare Differential Diagnosis of Renomegaly by Gaurang Modi, Irappa Madabhavi, Harsha Panchal, Asha Anand, Apurva Patel, Sonia Parikh, Swaroop Revannasiddaiah

“…So he was subsequently offered palliative chemotherapy in form of ifosfamide and adriamycin. CT abdomen shows partial response after 3 cycles of chemotherapy according to RECIST criteria.…”
Get full text

In silico evaluation, characterization, and in vitro anticancer activity of curcumin–nimbin loaded nanoformulation in HCT-116 cell lines by Arumugam Madeswaran, Selvam Tamilazhagan, Sellappan Mohan

“…Colorectal cancer is one of the most prevalent malignancies worldwide and a leading cause of mortality. Chemotherapy medications are often limited in use due to issues like drug resistance, P-glycoprotein efflux, and relapse of chemotherapy. …”
Get full text

Management and Outcomes of Male Breast Cancer in Zaria, Nigeria by Adamu Ahmed, Yahaya Ukwenya, Adamu Abdullahi, Iliyasu Muhammad

“…After evaluation patients were treated with modified radical mastectomy. Combination chemotherapy was given to patients with positive axillary lymph nodes. …”
Get full text

Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes by Saloni Mangal, Abhijit Debnath, Rupa Mazumder, Avijit Mazumder, Rajesh Kumar Singh, Jahanvi Sanchitra, S.K. Asif Jan, Pratibha Pandey, Bimlesh Kumar, Anil Kumar Singh

“…Heterogeneity of the disease, resistance to chemotherapy, and side effects such as nausea and vomiting, fatigue, anemia, neuropathy, hair loss, and skin and nail changes are associated with conventional therapeutics such as chemotherapy, radiation therapy, and targeted therapy. …”
Get full text

Bing and Neel Syndrome by S. Jennane, K. Doghmi, E. M. Mahtat, N. Messaoudi, B. Varet, M. Mikdame

“…A second complete remission was obtained with RFC chemotherapy regimen (rituximab, fludarabine, and cyclophosphamide). …”
Get full text

Ceftobiprole medocaril: clinical and pharmacological characteristics and possibilities of clinical use by Rachina S.A., Fedina L.V., Stafeev A.N., Kremneva A.O., Dekhnich A.V.

Get full text

Secondary Glioblastoma Multiforme in a Child with Disseminated Juvenile Pilocytic Astrocytoma by C. S. Amene, L. A. Yeh-Nayre, J. R. Crawford

“…We report a case of a 16-year-old girl with a history of disseminated juvenile pilocytic astrocytoma treated with chemotherapy and craniospinal radiation 9 years prior who developed sGBM in the absence of a tumor predisposition syndrome. …”
Get full text

Case report: Short-course hypofractionated radiation therapy combined with immune checkpoint inhibitors for the treatment of advanced ovarian mucinous cystadenocarcinoma by Xinan Wan, Mingxing Fang, Le Yuan, Hang Zhang, Dan Wang

“…BackgroundOvarian mucinous cystadenocarcinoma is a rare subtype of ovarian epithelial carcinoma that is resistant to platinum-based chemotherapy and has a poor prognosis, and there is no standard treatment plan for patients for whom multiline treatment has failed.Case presentationoma with FIGO stage IVB disease who was sequentially treated with paclitaxel liposomes+carboplatin, 5-Fu+CF+oxaliplatin, capecitabine+oxaliplatin, bevacizumab+FOLFOX4, S-1, and bevacizumab+oxaliplatin+raltitrexed chemotherapy. …”
Get full text

Arterial Stiffness in Breast Cancer Patients Treated with Anthracycline and Trastuzumab-Based Regimens by Özlem Yersal, Ufuk Eryilmaz, Hakan Akdam, Nezih Meydan, Sabri Barutca

“…The aim of this study is to analyze the arterial stiffness in breast cancer patients who are in the follow-up period after receiving anthracycline-based chemotherapy regimens with trastuzumab. Methods and Material. …”
Get full text

Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl by Laura Kasongo, Patricia Forget, Ramona Corina Nicolescu

“…However, little is known about central precocious puberty, as paraneoplastic manifestation of nephroblastoma or secondary to its specific chemotherapy. Here, we report a case of Wilms tumor and simultaneous precocious puberty in a 5-year-old girl. …”
Get full text

Successful Treatment of Acute Lymphoblastic Leukemia in a Child with Trisomy 21 and Complex Congenital Heart Disease with Mechanical Prosthetic Valve by Saima Alvi, Evan Shereck, Manraj K. S. Heran, George G. S. Sandor, Shahrad Rod Rassekh

“…A 10-year-old girl with trisomy 21 and complex congenital heart disease presented with acute lymphoblastic leukemia. Her chemotherapy required modifications due to poor baseline cardiac status and a mechanical prosthetic heart valve that was dependent on anticoagulation. …”
Get full text

Nuclear DNA Content of Fine Needle Aspirates of Invasive Ductal Carcinomas of the Breast by Sudip Sarker, Allan Spigelman, Marjorie Walker, Dulcie Coleman

“…Patients with aggressive breast cancers benefit from chemotherapy prior to surgery. If the biology of the breast cancers were better characterised pre‐operatively, more patients at risk could be offered chemotherapy. …”
Get full text

Comprehensive Management of Upper Tract Urothelial Carcinoma by Georgios Koukourakis, Georgios Zacharias, Michael Koukourakis, Kiriaki Pistevou-Gobaki, Christos Papaloukas, Athanasios Kostakopoulos, Vassilios Kouloulias

“…Several controversies remain in their management, including a selection of endoscopic versus laparoscopic approaches, management strategies on the distal ureter, the role of lymphadenectomy, and the value of chemotherapy in upper tract disease. Aims of this paper are to critically review the management of such tumors, including endoscopic management, laparoscopic nephroureterectomy and management of the distal ureter, the role of lymphadenectomy, and the emerging role of chemotherapy in their treatment.…”
Get full text

Hodgkin's Disease in Patients with HIV Infection by Michele Spina, Antonino Carbone, Annunziata Gloghini, Diego Serraino, Massimiliano Berretta, Umberto Tirelli

“…Moreover, in the last years the feasibility of high dose chemotherapy and peripheral stem cell rescue has allowed to save those patients who failed the upfront treatment. …”
Get full text

Unusual Paraneoplastic Presentation of Cholangiocarcinoma by Aman Opneja, Sonia Mahajan, Sargam Kapoor, Shanthi Marur, Steve Hoseong Yang, Rebecca Manno

“…Oral steroids and new regimen of chemotherapy were started. Rash improved and steroids were tapered off. …”
Get full text

Efficacy and safety of first-line PD-1/PD-L1 inhibitor in combination with CTLA-4 inhibitor in the treatment of patients with advanced non-small cell lung cancer: a systemic review... by Huimin Zhao, Shanshan Huang, Jianyu Wu, Yanlan Lu, Yue Zou, Haijian Zeng, Chunlan Li, Jin Wang, Xiaochen Zhang, Xiaochen Zhang, Siliang Duan, Siliang Duan, Weiming Liang

“…In terms of toxicity, CP had slightly fewer any AEs compared to chemotherapy (RR: 0.94, 95% CI: 0.91-0.97; p<0.05). …”
Get full text

High prevalence of resistance to macrolides and fluoroquinolones in Mycoplasma genitalium isolated from patients in two Russian megalopolises – Moscow and St. Petersburg in 2021– 2... by Edelstein I.A., Gushchin A.E., Gladin D.P., Romanov A.V., Negasheva E.S., Frigo N.V., Kozlov R.S., Potekaev N.N., Kozlova N.S., Borukhovich D.G.

Get full text

Gestational Choriocarcinoma Presenting with Lacrimal Gland Metastasis: A First Reported Case by Naushad A. B. Ahamed, Khalid Sait, Nisreen Anfnan, Khader Farwan, S. H. M. Nizamuddin, Saleh S. Baeesa

“…Based on her modified WHO risk factors scoring she was started on chemotherapy and whole brain radiotherapy, which resulted in a complete response. …”
Get full text

Cyclooxygenase Inhibitor Associated with Carboplatin in Treatment of Metastatic Nasal Carcinoma in Dog by Carlos Eduardo Fonseca-Alves, Aline Gonçalves Corrêa, Fabiana Elias, Sabryna Gouveia Calazans

“…After histopathological evaluation nasal carcinoma diagnosis was obtained. Chemotherapy was established with carboplatin 300 mg/m2 intravenously—four cycles with intervals of 21 days—and firocoxib 5 mg/kg orally every 24 hours for 7 months. …”
Get full text