Safety of Pegfilgrastim (Neulasta) in Patients with Sickle Cell Trait/Anemia by Pashtoon Murtaza Kasi, Mrinal M. Patnaik, Prema P. Peethambaram

“…Pegfilgrastim (Neulasta) is a recombinant filgrastim (human granulocyte colony-stimulating factor (G-CSF)) attached to a polyethylene glycol (PEG) molecule and is given as part of chemotherapy regimens that are associated with significant myelosuppression and risk for febrile neutropenia. …”
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Angiosarcoma Arising in a Patient with a 10-Year-Old Hemangioma by Michael J. Nathenson, Diana Molavi, Albert Aboulafia

“…She declined systemic adjuvant chemotherapy after a thorough discussion about the risks and benefits of chemotherapy, and she currently remains disease free one year after the surgery.…”
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Obstructive shock secondary to an unusual cause: primary cardiac lymphoma by Gregoire Ottavy, Laurent Camous, Claire Fieschi, Lucas Della Torre, Jean-David Pommier

“…Conclusion When a cardiac mass is associated with extracardiac symptoms indicative of a hematological malignancy, the preferred treatment is chemotherapy, and cardiac surgery should be avoided.…”
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The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer by Ranjeeta Thapa, George D. Wilson

“…Research to date suggests use of monoclonal antibodies against different CD44 variant isoforms and targeted inhibition of HA/CD44-mediated signaling combined with conventional radio/chemotherapy may be the most favorable therapeutic strategy for future treatments of advanced stage malignancies. …”
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Endovascular Treatment of Vertebral Column Metastases Using Intra-Arterial Cisplatin: Pilot Experience by Bohdan W. Chopko

“…Treatment of spinal column metastatic tumors is challenging, especially in the setting of progressive disease despite previous radiation and chemotherapy. Intra-arterial chemotherapy is an uncommonly used but established treatment for head and neck cancers, retinoblastoma, and glioblastoma. …”
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Bilateral Breast Masses with a Rare Etiology by Friederike Thieringer, Gideon Sartorius, Katrin Kalf, Viola Heinzelmann, Marcus Vetter

“…Six months after finishing chemotherapy the patient remained in complete remission. …”
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Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis by Ali Amanati, Nader Shakibazad, Bahman Pourabbas, Mohammad Hossein Nowroozzadeh, Soheila Zareifar, Omid Reza Zekavat

“…Viral infections, especially cytomegalovirus infection, may present with vague clinical pictures during any time of chemotherapy, which may not be easily distinguishable from bacterial or fungal retinitis and also chemotherapy-induced retinopathies. …”
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Perioperative Radiotherapy in the Management of Rectal Cancer by Lars Påhlman

“…However, when postoperative irradiation has been combined with chemotherapy, a survival benefit has been demonstrated. …”
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An Atypical Presentation of Sporadic Jejunal Burkitt’s Lymphoma by Pratik Naik, James Wang, Michael J. Brazeau, Domingo Rosario

“…Treatment consisted of bowel resection prior to chemotherapy due to concern for perforation with chemotherapy. …”
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Changing Management of Clinical Low-Stage Testicular Cancer by Timothy Gilligan

“…The management of clinical stage I testicular GCTs has grown more complicated due to the emergence of a brief course of chemotherapy as an additional treatment option for stage I seminomas and stage I nonseminomas. …”
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Delayed Migration of a WallFlex Enteral Stent Resulting in Jejunal Perforation by Phillip S. Ge, Rabindra R. Watson, David C. Chen, V. Raman Muthusamy

“…Four months later, while actively undergoing chemotherapy, he developed acute abdominal pain and was found to have delayed stent migration and jejunal perforation. …”
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Metastases to the Thyroid Presenting as a Metabolically Inactive Incidental Thyroid Nodule with Stable Size in 15 Months by Subhashini Yaturu, Raina A. Patel

“…A 63-year-old male with history of adenocarcinoma of the right lobe lung (5 years prior to presentation), treated with surgery and chemotherapy, followed by new adenosquamous lung cancer in the left lobe of the lung (one year prior to presentation), treated surgically followed by adjuvant chemotherapy, was referred to Endocrinology section for evaluation of an incidental thyroid nodule on CT chest. …”
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Anti-Toxoplasma Effects of Dracocephalum Polychaetum Essential Oil by Faham Khamesipour, Amirhossein Pourmohammad, Mohsen Jafarian-Dehkordi

“…Toxoplasma gondii is a common parasitic disease with a cosmopolitan prevalence, causing severe health problems. Although chemotherapy for toxoplasmosis is readily available, most have side effects. …”
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Growing Teratoma Syndrome by Anna Scavuzzo, Zael Arturo Santana Ríos, Nancy Reynoso Noverón, Miguel Angel Jimenez Ríos

“…Growing teratoma syndrome (GTS) is a rare clinical entity, which presents with enlarging teratomas masses of the retroperitoneum or other locations, occurring during or after systemic chemotherapy for the treatment of nonseminomatous germ cell of the testis (NSGCT), with normalised tumour markers. …”
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Comparison of Cantharidin Toxicity in Breast Cancer Cells to Two Common Chemotherapeutics by Katie M. Kern, Jennifer R. Schroeder

“…As part of a larger study synthesizing a more directed form of chemotherapy, we have begun to assess the efficacy of different potential toxins that could be delivered locally rather than systemically. …”
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Cerebral Sinus Venous Thrombosis due to Asparaginase Therapy by Youssef Alsaid, Shamshad Gulab, Mohammed Bayoumi, Saleh Baeesa

“…At one-year followup, he had complete response to chemotherapy for ALL, with residual mild left hemiparesis, and his MRI scans revealed recanalized venous sinuses. …”
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Primary ovarian peripheral primitive neuroectodermal tumor presented with breast metastasis; Case report by Razan Rabi, Majd Hamed Allah, Yusuf Dawabsheh

“…Despite treatment with radiotherapy and two cycles of high-dose Ifosfamide chemotherapy, her condition deteriorated, and she passed away in April 2024. …”
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Acute Cardiogenic Shock Induced by Infusional 5-Fluorouracil by Jeffrey Sulpher, Franco Dattilo, Susan Dent, Michele Turek, M. Neil Reaume, Christopher Johnson

“…A follow-up echocardiogram performed 5 days after initial presentation revealed an ejection fraction of 59 percent, with no evidence of wall motion abnormalities. Subsequent 5-FU chemotherapy was discontinued, and the patient went on to receive second-line chemotherapy.…”
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A Canadian Perspective on Systemic Therapy for Recurrent or Metastatic Nasopharyngeal Carcinoma by Anna Spreafico, Eric Winquist, Cheryl Ho, Brian O’Sullivan, Nathaniel Bouganim, Neil Chua, Sarah Doucette, Lillian L. Siu, Desiree Hao

“…The addition of anti-PD-1 monoclonal antibodies to chemotherapy has been shown to extend progression-free survival in recurrent r/m NPC compared to chemotherapy alone; however, approval of PD-1 inhibitors in Canada has lagged behind other jurisdictions where NPC is non-endemic. …”
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Real‐World Prevalence, Treatment Patterns, and Outcomes for Patients With HER2 (ERBB2)‐Mutant Metastatic Non‐Small Cell Lung Cancer, From a US‐Based Clinico‐Genomic Database... by Sarah Waliany, Misako Nagasaka, Leah Park, Clara Lam, Zoe Jiang, Feng Lin, Joel W. Neal

“…Results Among 9206 patients with mNSCLC, 164 (1.78%) met the eligibility criteria (mean age: 67.3 years, 63.4% White, 56.7% female, and 53.0% with a smoking history). 132/164 (80.5%) had at least one line of treatment. Platinum‐based chemotherapy (45.5%) and immune checkpoint inhibitor (ICI) with chemotherapy (28.0%) were the most frequently used first‐line treatments. …”
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