REPEATED THERAPEUTIC LEUKAPHERESIS - A SOLE TREATMENT DURING PREGNANCY AS A BRIDGE BEFORE TYROSINE KINASE INHIBITORS FOR A PREGNANT WOMAN WITH CHRONIC MYELOGENOUS LEUKEMIA – A CASE... by Ivan Tonev, Chavdar Botev, Georgui Balatzenko, Milcho Mincheff

“…Discussion: The classical treatment for CML includes tyrosine kinase inhibitors, chemotherapy and/or allogeneic haematopoietic stem cell transplantation. …”
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Clinical outcomes of dogs with high-grade cutaneous mast cell tumors by Siew Mei Ong, Siew Mei Ong, Charly McKenna, Christopher Pinard, Christopher Pinard, Christopher Pinard, Christopher Pinard, Danielle Richardson, Michelle L. Oblak

“…The limited therapeutic benefit of locoregional lymph node extirpation, combined with a persistently high metastatic rate despite systemic chemotherapy, highlights the critical need for more effective regional and systemic treatment approaches for HGMCT patients.…”
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Antiangiogenic therapy with recombinant human endostatin may improve blood perfusion of cervical node with necrosis in nasopharyngeal carcinoma patients: a preliminary study by usi... by Zhendong Yang, Huimin Xiao, Xigui Li, Zhuxin Wei, Min Kang, Rensheng Wang, Jianyuan Huang

“…The tumor microenvironment of the CNN has severely insufficient blood perfusion, thus leading to hypoxia and reducing the effect of radiotherapy (RT) and chemotherapy. By using contrast-enhanced ultrasound (CEUS) as a monitoring method, we conducted this study to assess whether antiangiogenic therapy (AT) with recombinant human endostatin (RHES) may improve blood perfusion of the CNN.Materials and methodsFifteen NPC patients with CNN were enrolled and underwent CEUS the day before and day 5 after AT with RHES initiation, respectively. …”
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Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer:... by Joachim G J V Aerts, Sjoerd H van der Burg, Martijn P Lolkema, Sai Ping Lau, Freek R van ’t Land, Marjolein Y V Homs, Casper H J van Eijck

“…Introduction The prognosis of patients with advanced pancreatic ductal adenocarcinoma (PDAC) is dismal and conventional chemotherapy treatment delivers limited survival improvement. …”
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Correlation of serum tumor necrosis factor-α, interleukin-4 and soluble interleukin-2 receptor levels with radiologic and clinical manifestations in active pulmonary tuberculosis by Levent Kart, Hakan Buyukoglan, Ishak O. Tekin, Remzi Altin, Zuhal Senturk, Inci Gulmez, Ramazan Demir, Mustafa Ozesmi

“…The TNF-α level was not statistically different in four groups before and after chemotherapy. Results of this study provided some evidence confirming the previously reported role of TNF-α, IL-4 and sIL 2R in the control of tuberculosis, but these cytokines were not found related with disease severity.…”
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Trends in Real-World Clinical Outcomes of Patients with Anaplastic Lymphoma Kinase (ALK) Rearranged Non-Small Cell Lung Cancer (NSCLC) Receiving One or More ALK Tyrosine Kinase Inh... by Lara Chayab, Natasha B. Leighl, Mina Tadrous, Christine M. Warren, William W. L. Wong

“…Patients were administered alectinib (n = 154), crizotinib (n = 80), or palliative-intent chemotherapy (n = 55) in the first-line treatment. There was a significant difference in first-line PFS between the treatment groups. …”
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Analysis of toxicity and mechanisms of busulfan in non-obstructive azoospermia: A genomic and toxicological approach integrating molecular docking, single-cell sequencing, and expe... by Yanggang Hong, Qichao Yuan, Yi Wang, Deqi Wang, Xiaoju Guan, Congde Chen

“…These findings offer new insights into the mechanisms of busulfan-induced NOA and suggest potential therapeutic targets for preserving male fertility in chemotherapy patients. This research advances the understanding of chemotherapy-induced reproductive toxicity and emphasizes the need for strategies to reduce its negative effects on fertility.…”
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Immune Modulation Effects of Lactobacillus casei Variety rhamnosus on Enterocytes and Intestinal Stem Cells in a 5-FU-Induced Mucositis Mouse Model by Chun-Yan Yeung, Jen-Shiu Chiang Chiau, Mei-Lien Cheng, Wai-Tao Chan, Szu-Wen Chang, Chuen-Bin Jiang, Hung-Chang Lee

“…Intestinal mucositis remains one of the most deleterious side effects in cancer patients undergoing chemotherapy. We hypothesize that the probiotics could preserve gut ecology, ameliorate inflammation, and protect epithelia via immune modulations of enterocytes and intestinal stem cells. …”
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Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK‐fusion‐positive lung cancer... by Koh Furugaki, Takaaki Fujimura, Narumi Sakaguchi, Yasutaka Watanabe, Ken Uchibori, Eisaku Miyauchi, Hidetoshi Hayashi, Ryohei Katayama, Shigeki Yoshiura

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Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study by Katarzyna Zięba, Kacper Jagiełło, Joanna Musialik, Łukasz Wierucki, Adam Hajduk, Małgorzata Mossakowska, Jerzy Chudek

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Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats by Yuanhang Wu, Jianlin Wu, Zhikun Lin, Qian Wang, Ying Li, Aman Wang, Xiu Shan, Jiwei Liu

“…Probiotic-based therapies have been shown to be beneficial for chemotherapy-induced mucositis. Previous research has demonstrated that a probiotic mixture (Bifidobacterium brevis, Lactobacillus acidophilus, Lactobacillus casei, and Streptococcus thermophilus) can ameliorate chemotherapy-induced mucositis and dysbiosis in rats, but the underlying mechanism has not been completely elucidated. …”
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Lung adenocarcinoma metastasis within a pituitary neuroendocrine tumor: a case report with review of literature by Koji Suzuki, Shigeyuki Tahara, Yujiro Hattori, Shinichiro Teramoto, Eitaro Ishisaka, Chie Inomoto, Robert Yoshiyuki Osamura, Akio Morita, Yasuo Murai

“…With continued chemotherapy, good control of both the primary and metastatic tumors was noted after 24 months after surgery. …”
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Diagnostic cholangioscopy for surgical planning of extrahepatic cholangiocarcinoma by Min Je Sung, Suk Pyo Shin, Chang-Il Kwon, Incheon Kang, Sung Hwan Lee, Seok Jeong Yang, Beodeul Kang, Hong Jae Chon, Gwangil Kim, Chansik An, Kwang Hyun Ko

“…Abstract The recent clinical outcomes of multi-regimen chemotherapy included prolonged survival and a high rate of conversion to surgery in Asian patients with advanced biliary tract cancer. …”
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MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma by Peng Xu, Fei-Hang Ge, Wen-Xin Li, Zhen Xu, Xue-Li Wang, Jing-Lan Shen, Ai-Bo Xu, Rong-Rong Hao

“…Furthermore, miR-147a mimic-treated human glioblastoma cells exhibited higher sensitivity to TMZ chemotherapy than those treated with the mimic control in vitro. …”
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Survival and prognostic factors for primary lung extranodal NK/T-cell lymphoma: a retrospective study of data from China and the SEER database by Qiuyu Li, Haoyu Zuo, Chengyang Liu, Jing Yang, Nini Dai

“…Most patients received chemotherapy (45%) or a combination of chemotherapy and radiotherapy (5%), but treatment data were incomplete for 40% of the cohort. …”
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Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia by Yuta Inagawa, Yukiko Komeno, Satoshi Saito, Yuji Maenohara, Tetsuro Yamagishi, Hiroyuki Kawashima, Taku Saito, Keiko Abe, Kuniko Iihara, Yasumasa Hatada, Tomiko Ryu

“…A 34-year-old woman was diagnosed with acute promyelocytic leukemia. Chemotherapy was administered following the JALSG APL204 protocol. …”
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Diagnosis and treatment of thyroblastoma: a case report and review of literature by Xiting Chen, Xiting Chen, Lijuan Xiong, Lijuan Xiong, Hongling Liu, Haoqiang Wang, Donghai Cheng, Wei Wang, Wenyuan He, Bo Xie, Juan Zhou

“…Despite local thyroid tumor resection, the disease continued to progress rapidly. However, chemotherapy with BEP led to a reduction in the tumor. …”
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Risk Factors of Noncompliance to Preventive Mass Drug Administration for Eliminating Lymphatic Filariasis: A Case-Control Study in Jawi District, Northwest Ethiopia by Fetene Mihretu, Gebeyehu Tsega, Melesse Belayneh, Mesafint Molla Adane

“…All individuals who are permanently living in the study area and registered on the annual chemotherapy registration book since 2015 were included in this study. …”
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Diagnostic performance of the DISQVER metagenomic sequencing tool for the identification of pathogens in febrile neutropenic patients: the ADNEMIA trial by Geneviève Héry-Arnaud, Christophe Burucoa, Marie Kempf, David Boutoille, Yohann Foucher, Philippe Lanotte, Maxime Pichon, Stéphane Corvec, Cécile Le Brun, Helene Pailhories

“…Introduction While intensive protocols in onco-haematology have improved survival rates for patients with haematological malignancies, they have also resulted in an increased incidence of infection associated with therapy-induced immunosuppression (including chemotherapy-induced febrile neutropenia; FN). The occurrence of FN, associated with high morbidity and mortality, necessitates broad-spectrum antibiotic therapy, occasioning delayed chemotherapy and resulting in a loss of opportunity for the patient. …”
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Metering effects in population systems by Erika T. Camacho, Christopher M. Kribs-Zaleta, Stephen Wirkus

“…These effects are illustrated by applications tomodels for chemotherapy dosing and for eating disorders in a school setting.…”
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