Possibilities of palliative chemotherapy in patients with locally advanced and metastatic pancreatic cancer by L. I. Moskvicheva, L. V. Bolotina

Subjects: Get full text

Adding checkpoint inhibitors to first-line chemotherapy for NUT carcinoma patients by Sarah Haebe, Gesa Schuebbe, Philipp Jurmeister, Michael von Bergwelt-Baildon, C. Benedikt Westphalen, Ulrich M. Lauer, Wolfgang G. Kunz, Marion Subklewe, Oliver Weigert

“…The tumor exhibited high PD-L1 expression and showed a notable response to immune checkpoint inhibitors when combined with platinum-based radio-chemotherapy. Our findings indicate that checkpoint inhibitors could play a critical role in treating NUT carcinoma, offering new therapeutic avenues and hope for patients with this challenging diagnosis. …”
Get full text

Modern Prospection for Hepatic Arterial Infusion Chemotherapy in Malignancies with Liver Metastases by Yi-Hsin Liang, Yu-Yun Shao, Jia-Yi Chen, Po-Chin Liang, Ann-Lii Cheng, Zhong-Zhe Lin

“…On account of the dual vascular supply system and the fact that most metastatic liver tumors are supplied by the hepatic artery, hepatic artery infusion chemotherapy (HAIC) is an appealing method for the treatment of liver metastases. …”
Get full text

Treatment of inoperable pancreatic adenocarcinoma with focused ultrasound and microbubbles in patients receiving chemotherapy by Margrete Haram, Rune Hansen, Ola Finneng Myhre, Stian Solberg, Naseh Amini, Bjørn Atle Angelsen, Catharina de Lange Davies, Eva Hofsli

Subjects: Get full text

PIDDosome Expression and the Role of Caspase-2 Activation for Chemotherapy-Induced Apoptosis in RCCs by Sebastian Heikaus, Igor Pejin, Helmut Erich Gabbert, Uwe Ramp, Csaba Mahotka

“…We, therefore, investigated their expression in renal cell carcinomas (RCCs) of the clear cell type in vivo and analysed the role of caspase-2 in chemotherapy-induced apoptosis in RCCs in vitro.…”
Get full text

Regional disparities in the use of intensive chemotherapy for AML in the Netherlands: does it influence survival? by Hester F Lingsma, David van Klaveren, Arjan A van de Loosdrecht, Anna van Rhenen, Otto Visser, Valery E P P Lemmens, Nikki van Leeuwen, Gerwin Huls, Z L Rana Kaplan, Eduardus F M Posthuma, Danielle van Lammeren-Venema, Tjeerd J F Snijders, Catharina H M J van Elssen, Peter A von dem Borne, Nicole M A Blijlevens, Jan J Cornelissen, Marc H G P Raaijmakers, Avinash G Dinmohamed

“…Objective Acute myeloid leukaemia (AML) prognosis is enhanced with intensive remission induction chemotherapy (ICT) in eligible patients. However, ICT eligibility perceptions may differ among healthcare professionals. …”
Get full text

Methotrexate-induced epidermal necrosis following intrathecal chemotherapy: A case report by Brad R. Woodie, BS, Stephany L. Vittitow, MD, Sweta Subhadarshani, MD, MRCP(SCE)

Subjects: Get full text

Does Apoptotic Index Predict the Response to Neoadjuvant Chemotherapy in Patients with Breast Carcinoma? by Gokce ASKAN, Oguzhan OKCU, Cigdem OZTURK, Seda DUMAN OZTURK, Bayram SEN, Recep BEDIR

Subjects: Get full text

Antimicrobial Regimens Prescribed by Canadian Physicians for Chemotherapy-Induced Febrile Neutropenic Episodes by Michel Laverdière, Eric J Bow, Coleman Rotstein, Stratis Ioannou, Danielle Carr, Narguess Moghaddam, the Canadian Fluconazole Study Group

“…OBJECTIVE: To study the antimicrobial management of cancer patients with chemotherapy-induced neutropenia by Canadian physicians.…”
Get full text

Optimal Feedback Control of Cancer Chemotherapy Using Hamilton–Jacobi–Bellman Equation by Yong Dam Jeong, Kwang Su Kim, Yunil Roh, Sooyoun Choi, Shingo Iwami, Il Hyo Jung

“…Cancer chemotherapy has been the most common cancer treatment. …”
Get full text

On drug resistance and metronomic chemotherapy: A mathematical modeling and optimal control approach by Urszula Ledzewicz, Shuo Wang, Heinz Schättler, Nicolas André, Marie Amélie Heng, Eddy Pasquier

Subjects: “…cancer chemotherapy…”
Get full text

Genetic Variations Affect Chemotherapy Outcomes: A Role of the Spindle-assembly Checkpoint by Sinjini Sarkar, Ranita Pal, Trisha Choudhury, Manisha Vernekar, Partha Nath, Vilas D. Nasare

“…This study investigated a SAC component, Budding Uninhibited by Benzimidazoles 3 (BUB3), its expression, and genetic variants in advanced ovarian cancer patients treated with paclitaxel–carboplatin chemotherapy. Among 80 patients, BUB3 expression correlated with chemosensitivity, suggesting its potential as a predictive marker for chemotherapy response. …”
Get full text

Comparing Health-Related Quality of Life of Cancer Patients under Chemotherapy and of Their Caregivers by Ioannis Vrettos, Konstantinos Kamposioras, Nick Kontodimopoulos, Evelina Pappa, Elissavet Georgiadou, Dionysios Haritos, Angelos A. Papadopoulos, Dimitris Niakas

“…Quality of life is highly influenced during the period of chemotherapy for both patients and caregivers and is often under reported. …”
Get full text

A Case of Unresectable Papillary Thyroid Carcinoma Treated with Lenvatinib as Neoadjuvant Chemotherapy by Hiroyuki Iwasaki, Soji Toda, Hiroyuki Ito, Daiji Nemoto, Daisuke Murayama, Yoichiro Okubo, Hiroyuki Hayashi, Tomoyuki Yokose

“…This case is reported as a successful case of neoadjuvant chemotherapy and interval debulking surgery.…”
Get full text

Effect of Cinnamon Essential Oil on the Chemotherapy-Induced Nausea and Vomiting of Cancer Patients by Shima Mehrabian, Batool Tirgari, Mina Beitollahi, Mansooreh Azizzadeh Forouzi, Behjat Kalantari Khandani

Subjects: Get full text

Preliminary Results of Hyperthermic Intraperitoneal Intraoperative Chemotherapy as an Adjuvant in Resectable Pancreatic Cancer by Antonios-Apostolos K. Tentes, Dimitrios Kyziridis, Stylianos Kakolyris, Nicolaos Pallas, Georgios Zorbas, Odysseas Korakianitis, Christos Mavroudis, Nicolaos Courcoutsakis, Panos Prasopoulos

“…Hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) may be used in order to control local-regional recurrences. …”
Get full text

Cytogenetically Unrelated Clones in Acute Myeloid Leukemia Showing Different Responses to Chemotherapy by Kohei Kasahara, Masahiro Onozawa, Naohiro Miyashita, Emi Yokohata, Miho Yoshida, Minoru Kanaya, Mizuha Kosugi-Kanaya, Ryo Takemura, Shojiro Takahashi, Junichi Sugita, Akio Shigematsu, Mutsumi Takahata, Shinichi Fujisawa, Daigo Hashimoto, Katsuya Fujimoto, Tomoyuki Endo, Takeshi Kondo, Takanori Teshima

“…We concluded that one clone was de novo AMoL with chromosome 6, 8, 11, 13, and 19 trisomy and that the other was acute myeloid leukemia with myelodysplasia-related changes　(AML-MRC) with chromosome 7 monosomy showing different responses to chemotherapy. Simultaneous onset of cytogenetically unrelated hematological malignancies that each have a different disease status is a rare phenomenon but is important to diagnose for a correct understanding of the disease status and for establishing an appropriate treatment strategy.…”
Get full text

Intra-Arterial Chemotherapy with Doxorubicin and Cisplatin Is Effective for Advanced Hepatocellular Cell Carcinoma by Ming-Chun Ma, Yen-Yang Chen, Shau-Hsuan Li, Yu-Fan Cheng, Chih-Chi Wang, Tai-Jan Chiu, Sung-Nan Pei, Chien-Ting Liu, Tai-Lin Huang, Chen-Hua Huang, Yu-Li Su, Yen-Hao Chen, Sheng-Nan Lu, Kun-Ming Rau

“…Advanced hepatocellular carcinoma (HCC) remains a fatal disease even in the era of targeted therapies. Intra-arterial chemotherapy (IACT) can provide therapeutic benefits for patients with locally advanced HCC who are not eligible for local therapies or are refractory to targeted therapies. …”
Get full text

Prognostic significance of tumor angiogenesis markers in advanced cervical cancer undergoing chemotherapy by I Nyoman Bayu Mahendra, I Gde Sastra Winata, William Alexander Setiawan, Ida Bagus Agung Widnyana Putra, Putu Bagus Darmayasa

Subjects: “…advanced cervical cancer, chemotherapy, prognosis, vegf, vegfr…”
Get full text

Sulforaphane in alternative cancer chemotherapy: From carcinogenesis suppression to drug resistance reversal by Seyed Mohammad Doodmani, Payman Rahimzadeh, Najma Farahani, Seyedalireza Mirilavasani, Mina Alimohammadi, Noushin Nabavi, Elmira Alaei, Afshin Taheriazam, Maryam Abedi, Nadia Shafiee, Salman Daneshi, Mehrdad Hashemi

“…The management and treatment of cancer have posed significant challenges in recent years. Conventional chemotherapy, despite its widespread use, has encountered obstacles such as the emergence of drug resistance. …”
Get full text