Early Recurrence of Ovarian Cancer during Pregnancy after Primary Staging Surgery in the First Trimester by Munetoshi Akazawa, Kazunori Hashimoto

“…Omitting adjuvant chemotherapy during pregnancy, we continued the prenatal checkups in the outpatient. …”
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A Rare Case of Metastatic Primary Peritoneal Ependymoma: A Case Report and Literature Review by Ben Man Fei Cheung, Johnny Kin Sang Lau, Anthony W. I. Lo, Mai-Yee Luk, Kwok Keung Yuen

“…Etoposide containing the chemotherapy regimen is effective in the treatment of peritoneal ependymoma. …”
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Primary Diaphragmatic Dedifferentiated Liposarcoma in a Young Female Patient after Delivery by Shinya Sakata, Chieko Yoshida, Sho Saeki, Susumu Hirosako, Hidenori Ichiyasu, Hirotsugu Kohrogi

“…We initiated doxorubicin chemotherapy, and the tumor mass reduced. After that, we performed vascular embolization along with chemotherapy, but tumor size did not reduce. …”
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Role of immunotherapy in the overall survival of gastrointestinal cancer patients with liver metastases by Taoyuan M Beninato, Saber A Amin, Michael J Baine, Chi Lin

“…Chemoimmunotherapy with radiotherapy to metastatic sites (except liver) was associated with improved OS (HR 0.771; 95% CI 0.706–0.842; p < 0.001) compared to chemoradiation.Conclusion: Immunotherapy plus chemotherapy or chemoradiation was associated with improved OS compared with chemotherapy or chemoradiation without immunotherapy.…”
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What do double-check routines actually detect? An observational assessment and qualitative analysis of identified inconsistencies by Yvonne Pfeiffer, Chantal Zimmermann, David L. B. Schwappach

“…Objectives Double checking is used in oncology to detect medication errors before administering chemotherapy. The objectives of the study were to determine the frequency of detected potential medication errors, i.e., mismatching information, and to better understand the nature of these inconsistencies.Design In observing checking procedures, field noteswere taken of all inconsistencies that nurses identified during double checking the order against the prepared chemotherapy.Setting Oncological wards and ambulatory infusion centres of three Swiss hospitals.Participants Nurses’ double checking was observed.Outcome measures In a qualitative analysis, (1) a category system for the inconsistencies was developed and (2) independently applied by two researchers.Results In 22 (3.2%) of 690 observed double checks, 28 chemotherapy-related inconsistencies were detected. …”
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In Vitro Evaluation of a Stable Monomeric Gold(II) Complex with Hematoporphyrin IX: Cytotoxicity against Tumor and Kidney Cells, Cellular Accumulation, and Induction of Apoptosis by Georgi Momekov, Dilyan Ferdinandov, Spiro Konstantinov, Sonja Arpadjan, Daniela Tsekova, Galina Gencheva, Panayot R. Bontchev, Margarita Karaivanova

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Inhibition of KLF5 promotes ferroptosis via the ZEB1/HMOX1 axis to enhance sensitivity to oxaliplatin in cancer cells by Zheng Zhang, Huaxiang Xu, Junyi He, Qiangsheng Hu, Yuxin Liu, Zijin Xu, Wenhui Lou, Wenchuan Wu, Lei Zhang, Ning Pu, Chenye Shi, Yaolin Xu, Wenquan Wang, Liang Liu

“…These results reveal a critical role of KLF5 in sensitized chemotherapy of pancreatic cancer, and suggest that ferroptosis combined with platinum-based chemotherapy rather than gemcitabine-based chemotherapy is expected to bring better therapeutic effects.…”
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Hodgkin Lymphoma Mimicking Inflammatory Breast Carcinoma: A Rare Case with Diagnostic Challenge and Novel Treatment by Eleni Thodou, Maria Befani, George Triantafyllidis, Theodosia Choreftaki, George Kanellis, Nikolaos Giannakoulas

“…The patient after first-line chemotherapy developed relapse/refractory disease. Salvage chemotherapy regimens were applied with poor results and severe toxicity. …”
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Prognostic factors in hereditary breast cancer: A review by Ziske Maritska, Sarmoko

“…Despite this, BRCA mutation carriers exhibit higher sensitivity to platinum-based chemotherapy and PARP inhibitors, potentially improving outcomes. …”
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Small-Cell Lung Cancer with Positive Anti-NMDAR and Anti-AMPAR Antibodies Paraneoplastic Limbic Encephalitis by Sabina Boangher, Pascal Mespouille, Corina-Mihaela Filip, Sophie Goffette

“…After the completion of 3 cycles of chemotherapy her neurological status temporarily worsened. …”
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A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis by Aria Mahtabfar, Hamoon Eshraghi, Melroy D’Souza, William Berrigan, Kathleen Casey

“…A 78-year-old male with a history of gastroesophageal cancer treated with chemotherapy and radiation presented to the hospital after a fall at home. …”
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Successful Combined Treatment of a Patient with Borderline Resectable Liver Metastasis of Colorectal Cancer by O. Yu. Stukalova, A. A. Polikarpov, A. V. Moiseenko, D. A. Granov

“…Liver resection could not be performed due to the small future residual volume, and systemic chemotherapy was not effective. The patient underwent 3 cycles of regional chemotherapy. …”
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Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma by Kei Nagai, Hiroaki Tachi, Kohei Inoue, Atsushi Ueda

“…We recently encountered a patient with malignant mesothelioma coincident with nephrotic syndrome and cryoglobulinemia in the course of chemotherapy. A 60-year-old man employed as a building painter was diagnosed with malignant mesothelioma by lung biopsy two years earlier and was started on chemotherapy. …”
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Natural products as part of triple negative breast cancer by Yozlem Kobakova, Maria Moneva-Sakelarieva, Spiro Konstantinov, Georgi Momekov, Stefka Achkova Ivanova, Ventseslava Atanasova, Maria Chaneva, Radoslav Tododrov, Nikolay Bashev, Petar Atanasov

“…Chemotherapy is the most common of these options. The serious side effects of chemotherapy significantly limit its use. …”
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Paraneoplastic Dermatomyositis Associated with Metastatic Seminoma by Hidekazu Yoshie, Ryuto Nakazawa, Wataru Usuba, Hiroya Kudo, Yuichi Sato, Hideo Sasaki, Tatsuya Chikaraishi

“…Lymph node metastases completely disappeared and swallowing and respiration fully normalized after completing chemotherapy. We believe that this clinical success was due to our decision to initiate chemotherapy even in such a weak patient.…”
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Brentuximab Vedotin Treatment for Primary Refractory Hodgkin Lymphoma by Hung-Bo Wu, Shyh-An Yeh, Huei-Yung Chen

“…Up to 40% of patients with advanced Hodgkin lymphoma (HL) become refractory or relapsed after current standard chemotherapy, among which primary refractory HL confers a particularly poor outcome. …”
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Effect of primary tumor volume on survival of concurrent chemoradiotherapy in stage IV non‐small cell lung cancer by Xiaxia Chen, Wei Zhang, Lan Luo, Shimei Fu, Dongdong Cao, Shengfa Su, Qingsong Li, Wengang Yang, Yichao Geng, Bing Lu, Weiwei Ouyang

“…The number of median chemotherapy cycles was 4 (2–6), and the cut‐off value of the planning target volume (PTV) dose of the primary tumor was 63 Gy (30–76.5 Gy). …”
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Efficacy of PARPi re-maintenance therapy for recurrent ovarian cancer by Yulin Wang, Yunjie Yang, Binghong Guo, Binghong Guo, Xiaoyan Li, Renakezi Tuersun, Ye Cao, Jundong Li, Jihong Liu, Su Li, Tao Liu, Yongwen Huang

“…This study aims to investigate the efficacy and associated factors of PARPi re-maintenance therapy in PSROC patients in China.MethodsIn this study, there were 201 patients with PSROC who had received maintenance therapy previously and achieved complete or partial response after platinum-based chemotherapy upon recurrence. The re-maintenance therapy group (Re-PARPi) and chemotherapy alone group (Chem-A) were categorized based on whether PARPi was reused after recurrence chemotherapy. …”
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Evaluating the influence of anti-PD-1 immunotherapy combined with IMRT on thyroid dysfunction in nasopharyngeal carcinoma by Liqianqi Chen, Zihuang Li, Xianming Li, Shihai Wu, Long Gong, Gang Xu, Shanyi Chen, Yucong Zhang

“…Subclinical hyperthyroidism (33.9%) was most common in the immunotherapy plus chemoradiotherapy group, while subclinical hypothyroidism (23.9%) was most common in the immunotherapy plus chemotherapy group. Compared to the immunotherapy plus chemotherapy group, the immunotherapy plus chemoradiotherapy group showed higher incidence and severity of hyperthyroidism (median peak FT4 concentration: 19.11 pmol/L vs 16.21 pmol/L) (P=0.001). …”
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NOS2 as a prognostic biomarker for early-onset colorectal cancer based on public data and clinical validation analysis by Chaoqun Xing, Lipeng Zhao, Weiwei Zou, Xie Peng, Xiao-Liang Xing, Jie Li

“…Sensitivity analysis of chemotherapy drugs showed that NOS2 was significantly correlated with several chemotherapy drugs, such as MG.132_1862, BMS.754807_2171, and GEN.317_1926. …”
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