The Immune Landscape and Its Potential for Immunotherapy in Advanced Biliary Tract Cancer by Andry Santoso, Iris Levink, Rille Pihlak, Ian Chau

“…The addition of immune checkpoint inhibitors (ICI) to chemotherapy have shown only a marginal benefit over chemotherapy alone due to the complex tumour immune microenvironment of these cancers. …”
Get full text

Preparation and Synergistic Anti-Tumor Effect of Iridium Oxide Nanocomposites under Microscope by Xudong He, Feng Xiang, Zhangyi Xu

“…Through a retrospective analysis of an experiment, IrOx nanoparticles were prepared by direct hydrothermal hydrolysis and loaded with chemotherapy drug adriamycin to construct nanodrug-loaded complex IrOx@DOX. …”
Get full text

Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma by Kheng-Wei Yeoh, N. George Mikhaeel

“…This together with the availability of effective chemotherapy has encouraged a combined modality approach for early-staged disease and the omission of radiotherapy in advanced-staged disease. …”
Get full text

Comparative efficacy and safety of first-line neoadjuvant therapy for early-stage non-small cell lung cancer based on immune checkpoint inhibitor therapy: a systematic review and n... by Linfeng Wang, Guangda Zheng, Yue Hu, Ayidana Maolan, Yue Luo, Yue Li, Rui Liu

“…Nivolumab plus chemotherapy provided the best surgical resection rate (OR = 1.71, 95% CI:0.87–3.40) and pembrolizumab plus chemotherapy provided the best R0 surgical resection rate (OR = 2.20, 95% CI:1.28–3.79). …”
Get full text

Postpartum choriocarcinoma complicated by uterine perforation: A case report and literature review by Rayan R. Salahaldin, Mais E. Abubaker, Ghada M. Abdalqader, Anas R. Tuqan, Basel A. Zaben, Iba Barghouthi

“…Despite initial single-agent chemotherapy, disease progression led to uterine perforation and hemoperitoneum, requiring emergency surgery. …”
Get full text

A Cost-effectiveness Analysis of Brentuximab Vedotin in Relapsed or Refractory Systemic Anaplastic Large Cell Lymphoma by Margaret Hux, Denise Zou, Esprit Ma, Peter Sajosi, Andreas Engstrom, Ross Selby, Eugene Benson, Andrew Briggs, Vijayveer Bonthapally

“…Comparison with conventional chemotherapy was based on data from the Canadian British Columbia Cancer Agency registry from 40 patients starting salvage chemotherapy after front-line treatment between 1980 and 2012. …”
Get full text

Cost-effectiveness of the addition of sintilimab as a first-line therapy for locally advanced or metastatic oesophageal squamous cell carcinoma: a Chinese healthcare system perspec... by Cuicui Yu, Yingqi Wu, Yadi Geng, Hui Yan, Pengli Zhu, Peng Ji, Fei Wu, Lijuan Ning, Yubin Feng, Aizong Shen

“…Results Sintilimab-based chemotherapy was more costly ($31699.21 vs. $20687.42) and more effective (0.74 vs. 0.53) than placebo-based chemotherapy, resulting in an ICER of $51908.19 /QALY, which is greater than the willingness-to-pay (WTP) threshold of China ($38223/QALY). …”
Get full text

The Clinical Impact of Vascular Endothelial Growth Factor/Receptor (VEGF/R) Inhibitors on Voice by Christina Hui Lee Ng, Edward J. Damrose

“…In one patient, who remained on chemotherapy, there was persistent bowing. Conclusions. …”
Get full text

Hubungan Depresi dan Sindrom Dispepsia pada Pasien Penderita Keganasan Yang Menjalani Kemoterapi di RSUP DR. M. Djamil Padang by Mona Rahmi Rulianti1, Dedy Almasdy, Arina Widya Murni

“…The final conclusion of this study is that there are sufficient and direct relationship (p &lt;0.01) between depression and dyspepsia syndrome that occurs in patients with malignancies who are undergoing chemotherapy.<br />Keywords: cancer, chemotherapy, depression, dyspepsia syndrome</p>…”
Get full text

Computed tomography–guided percutaneous transthoracic core needle biopsy for the diagnosis of mediastinal masses by Sukanta Kodali, Sourindra Nath Banerjee, Jaydip Deb, Pulak Kumar Jana

“…The patient received chemotherapy and remained well 6 months after the treatment. …”
Get full text

Protective Effects of Aqueous Extract of Solanum nigrum Linn. Leaves in Rat Models of Oral Mucositis by Alkesh Patel, Subhankar Biswas, Muhammed Haneefa Shoja, Grandhi Venkata Ramalingayya, K. Nandakumar

“…Oral mucositis is one of the most debilitating side effects in patient undergoing chemotherapy or chemoradiotherapy. Leaves of the plant Solanum nigrum are used in folklore medicine to treat oral ulcers in India. …”
Get full text

A New Rapidly Growing Dome-Shaped Choroidal Lesion in an Eye with Treated Retinoblastoma by Babak Masoomian, Maria Pefkianaki, Fariba Ghassemi, Hamid Riazi-Esfahani

“…The patient received 12 cycles of intravenous chemotherapy, intra-arterial chemotherapy (IAC), and intravitreal chemotherapy for the left eye and focal adjuvant therapy (laser thermotherapy and cryotherapy) for both eyes. …”
Get full text

CLINICAL CASE OF TREATMENT OF INVASIVE UROTHELIAL CANCER OF THE UPPER URINARY TRACT. PROBLEMS OF COMBINED TREATMENT by A. A. Klimenko, I. P. Kostyuk, O. B. Karyakin, S. A. Moserov, Z. N. Shavladze, I. N. Zaborsky, V. S. Chaykov, M. E. Tarasova

“…This article presents a clinical observation of the treatment of recurrent invasive urothelial cancer of the upper urinary tract using surgical and chemotherapy treatments. During the treatment, surgical treatment and 2 chemotherapy lines were performed. …”
Get full text

Surprise Lymph Node Histology in a Patient with Ovarian Serous Carcinoma by Jayanthi Karunanithi, Inny Busmanis

“…Following three cycles of chemotherapy, she underwent total hysterectomy, bilateral salpingo-oophorectomy cytoreductive surgery with lymphadenectomy, and multiple peritoneal biopsies. …”
Get full text

Successful Resection of Isolated Para-Aortic Lymph Node Recurrence from Advanced Sigmoid Colon Cancer following 156 Courses of FOLFIRI Regimen by Kaoru Takeshima, Kazuo Yamafuji, Atsunori Asami, Hideo Baba, Nobuhiko Okamoto, Hidena Takahashi, Chisato Takagi, Kiyoshi Kubochi

“…Few reports have described the successful resection of isolated PLN involvement from CRC following chemotherapy. We report the case of a 63-year-old man who underwent sigmoidectomy for sigmoid colon cancer at our hospital. …”
Get full text

Desmoplastic Small Round Cell Tumor of the Abdomen and Pelvis: Clinicopathological Characters of 12 Cases by Guangzhao Zhang, Guangjun Liu, Dahua Zhao, Xijun Cui, Gang Li

“…In all 12 cases, 6 cases underwent operation and adjuvant chemotherapy (group 1, 6/12, 50%). The other 6 cases were diagnosed by fine needle aspiration or exploratory laparotomy biopsy (group 2, 6/12, 50%); all cases received four to six courses of multiple agents chemotherapy, respectively. …”
Get full text

Assessment of Suspected Breast Lesions in Early-Stage Triple-Negative Breast Cancer during Follow-Up after Breast-Conserving Surgery Using Multiparametric MRI by Lamiss Mohamed Abd El Aziz Sad, Naglaa Lofty Dabees, Dareen Abd El-Aziz Mohamed, Amr Tageldin, Samar Galal Younis

“…It involved 50 patients with early-stage TNBC who were treated with BCS, followed by radiotherapy with/without chemotherapy. The suspected lesions were evaluated during the follow-up period by sonomammography. …”
Get full text

Efficacy and safety of selective pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors in FGFR-altered urothelial carcinoma by Yuxuan Song, Yiqing Du, Shan Jiang, Yun Peng, Xing Luo, Tao Xu

“…However, the comparative efficacy and safety of FGFRi with ICI or chemotherapy remains under debate. We analyzed 865 UC patients including 447 with FGFRi and 418 with ICI or chemotherapy. …”
Get full text

Proceedings of clinical trials on bile tract cancer by XIONG Yichen, YANG Ziyi, SANG Yuer, GONG Wei

“…BILCAP and ASCOT studies confirm the vital role of adjuvant chemotherapy in resectable BTC. Irinotecan as a second-line chemotherapy agent for patients with advanced BTC has also been confirmed by recent research data. …”
Get full text

Enfortumab vedotin plus pembrolizumab for previously untreated locally advanced or metastatic urothelial carcinoma: a cost-effectiveness analysis by Youwen Zhu, Kun Liu, Hong Zhu, Shan Li, Dan Yuan

“…Objectives: To guide the choice of EV plus pembrolizumab or chemotherapy for patients with previously untreated la/mUC. …”
Get full text