Recurrent Diffuse Large B-Cell Lymphoma with the Initial Manifestation of Retinal Involvement by Wan-Ting Yeh, Jen-Tsun Lin*

“…Hence, the patient received six cycles of systemic chemotherapy along with intrathecal chemotherapy and refused either radiation therapy or bone marrow transplantation. …”
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Single-Agent Thalidomide for Treatment of Malignant Paraganglioma of the Organ of Zuckerkandl by Mackenzie L. Shindorf, Prabir K. Chaudhuri

“…Current therapeutic options include surgical resection, chemotherapy (CVD therapy), MIBG-radiotherapy, somatostatin analogues, and combination targeted therapies such as temozolomide and thalidomide. …”
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Exploring and detecting predictors associated with survival and mortality of cervical cancer patients: a 10-year retrospective study by Shaba Muneeha, Raushan Kumar Chaudhary, Vijith Vittal Shetty, Soumya Patil, Uday Venkat Mateti

“…Using cox regression analysis, advanced age (age > 50 years: hazard ratio (HR): 1.82), underweight (BMI < 18.5: HR:1), postmenopause (HR:1), advanced stage of cervical cancer (Stage I, Stage II, Stage III, Stage IV: HR:1, HR:2.78, HR:10.08, HR:20.81), poorly differentiated cervical cancer (HR:1.70), radiation therapy (HR:4.86), chemotherapy (HR:6.55) or chemoradiation therapy (HR:3.31) and surgery plus chemotherapy (HR: 4.55) were identified to be significant predictors of mortality among cervical cancer patients. …”
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Current developments in personalized treatment strategies for elderly acute myelogenous leukemia patients by Xueting Hou, Jizhang Bao

“…Acute myelogenous leukemia(AML) is a life-threatening hematologic malignancy that predominantly affects the elderly.Currently, chemotherapy and hematopoietic stem cell transplantation are the primary treatment modalities for AML, though their clinical application is limited in older patients.Recent years have seen the development of novel molecular targeted therapies, such as isocitrate dehydrogenase 1/2 (IDH1/2) and Feline macrophage stimulator-like tyrosine kinase 3 (FLT3) inhibitors, as well as individualized approaches like chimeric antigen receptor T-cell (CAR-T) therapy.However, due to patient heterogeneity and drug resistance, treatment outcomes for elderly AML remain unsatisfactory, underscoring the need for more precise and safer individualized treatment strategies.The combination of chemotherapy with novel targeted or immunotherapies shows promise as a future treatment direction.This research reviews the latest advances in the treatment of elderly AML, with a focus on achieving more individualized and safer therapeutic approaches.…”
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Pulmonary Blastoma: A Rare Primary Lung Malignancy by Mahmoud S. Alahwal, Iqbal H. Maniyar, Faiza Saleem, Mariam Alshiekh

“…We report this rare malignancy with a review of literature, and the potential to use adjuvant chemotherapy in the management of this condition.…”
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Novel Therapies for Aggressive B-Cell Lymphoma by Kenneth A. Foon, Kenichi Takeshita, Pier L. Zinzani

“…In MCL, a mature B-cell lymphoma, the addition of rituximab to conventional chemotherapy regimens has increased response rates, but not survival. …”
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HIV-Associated Hodgkin's Lymphoma: Prognosis and Therapy in the Era of cART by Caron A. Jacobson, Jeremy S. Abramson

“…Before the introduction of cART, patients with HIV-HL had lower response rates and worse outcomes than non-HIV-infected HL patients treated with conventional chemotherapy. The introduction of cART, however, has allowed for the delivery of full-dose and dose-intensive chemotherapy regimens with improved outcomes that approach those seen in non-HIV infected patients. …”
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Clinical Biology and Potential Use of Thrombopoietin by Russell Basser

“…However, one of these agents, interleukin-11, was successfully shown to reduce the incidence of severe thrombocytopenia in patients receiving dose-intensive chemotherapy, and has now received approval from the United States Food and Drug Administration for this purpose. …”
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Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer by Masahiro Itonaga, Masayuki Kitano

“…Obstructive jaundice often leads to poor general conditions and acute cholangitis, interfering with surgery and chemotherapy and requiring biliary drainage. The first choice of treatment for biliary drainage is the endoscopic transpapillary approach. …”
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Primary Pulmonary Synovial Sarcoma: A Case with Unique and Impressive Computed Tomography Findings by Jaspreet S Kambo, Bonnie Richardson, Diana N Ionescu, Tracy Tucker, Greg Kraushaar

“…The present case highlights complications of a rare malignancy and demonstrates positive response to ifosfamide-based chemotherapy in the setting of PPSS.…”
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Revolutionizing acute myeloid leukemia treatment: a systematic review of immune-based therapies by Ugochi Ebinama, Binsah George

“…Abstract The established protocol for the management of acute myeloid leukemia (AML) has traditionally involved the administration of induction chemotherapy, followed by consolidation chemotherapy, and subsequent allogeneic stem cell transplantation for eligible patients. …”
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Multidisciplinary Treatment for Colorectal Peritoneal Metastases: Review of the Literature by Shaobo Mo, Guoxiang Cai

“…With the advancement of surgical techniques, hyperthermic intraperitoneal chemotherapy (HIPEC), and multidisciplinary treatment in recent years, the cognition and treatment strategies of colorectal peritoneal metastases (CPM) have changed dramatically. …”
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AM3, an Oral BRM: Protective Agent against Iatrogenic Bone-Marrow and Liver Damage in Breast Cancer Patients under Conventional Adjuvant Radiochemotherapy by Vicente G Villarrubia, Paula Marquez, Jose Cobo, Guillermo J Sada

“…The incidence of thrombocytopenia in patients receiving combined radio-chemotherapy only was 70% compared with 6% observed in patients also receiving AM3 treatment. …”
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Escin Chemosensitizes Human Pancreatic Cancer Cells and Inhibits the Nuclear Factor-kappaB Signaling Pathway by A. Rimmon, A. Vexler, L. Berkovich, G. Earon, I. Ron, S. Lev-Ari

“…Moreover, Escin sensitized pancreatic cancer cells to chemotherapy. Further translational research is required.…”
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Humoral Hypercalcemia of Malignancy with a Parathyroid Hormone-Related Peptide-Secreting Intrahepatic Cholangiocarcinoma Accompanied by a Gastric Cancer by Katsushi Takeda, Ryosuke Kimura, Nobuhiro Nishigaki, Shinya Sato, Asami Okamoto, Kumiko Watanabe, Sachie Yasui

“…Chemotherapy reduced the size of the ICC and decreased the serum PTHrP level. …”
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The patterns of presentation, management and outcomes of breast cancer patients at a tertiary health facility in Sierra Leone by Constance Cummings-John, Abdulai Jawo Bah, Isaac Olufemi Smalle, Caesar Cho Challe, Babatunde Duduyemi, Temidayo Ogundiran

“…With respect to treatment modalities, surgery, chemotherapy, and hormonal therapy were provided to patients — with 120 (48%) mastectomies, 73 (29.2%) neoadjuvant chemotherapy, 84 (33.6%) adjuvant chemotherapy, 98 (39.2%) hormonal therapy, 35 (14.0%) palliative care and approximately 38 (15.2%) refused or did not initiate any treatment. …”
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Efficacy and safety of molecular targeted therapies in nasopharyngeal carcinoma: a network meta-analysis by Htet Htet, Jwala Rebacca James Anaghan, Heethal Jaiprakash, Ismail Abdul Sattar Burud, Thiruselvi Subramaniam, Igor Iezhitsa, Renu Agarwal

“…Methods Databases were searched from inception to Aug 2023, comparing molecular targeted therapies (MTT) with conventional chemotherapy, chemotherapy or surgery. Study screening, data extraction, and data analysis were conducted independently by two investigators. …”
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Cell Therapy for Chemically Induced Ovarian Failure in Mice by Paula Terraciano, Tuane Garcez, Laura Ayres, Isabel Durli, Melchiani Baggio, Cristiana Palma Kuhl, Claudia Laurino, Eduardo Passos, Ana Helena Paz, Elizabeth Cirne-Lima

“…Studies modeling this in mice have shown that cells transplantation generates donor-derived oocytes in chemotherapy-treated recipients. This study was conducted to further clarify the impact of cell transplantation from different sources on female reproductive function after chemotherapy using a preclinical mouse model. …”
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Prognostic and Predictive Value of CpG Island Methylator Phenotype in Patients with Locally Advanced Nonmetastatic Sporadic Colorectal Cancer by Yuwei Wang, Yadong Long, Ye Xu, Zuqing Guan, Peng Lian, Junjie Peng, Sanjun Cai, Guoxiang Cai

“…In patients with CIMP positive tumor, those receiving adjuvant chemotherapy had a poor DFS than those without adjuvant chemotherapy (P=0.023). …”
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A Case of Significant Response to Olaparib in a Patient with Primary Peritoneal Carcinosarcoma Diagnosed by Laparoscopic Surgery by Satoshi Nagamata, Yukiko Nakasuji, Keitaro Yamanaka, Maho Azumi, Keiichi Washio, Maho Shimizu, Ryosuke Takahashi, Kazuyo Matsumoto, Yuka Murata, Kaho Suzuki, Masashi Deguchi, Hideto Yamada, Yoshito Terai

“…The pathological diagnosis was carcinosarcoma, and the patient received chemotherapy with docetaxel and carboplatin. After three cycles of chemotherapy, the interval debulking surgery was attempted but resulted in suboptimal results. …”
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