Challenges and motivating factors for integrating geostatistical models in targeted schistosomiasis control: A qualitative case study in Northwestern Tanzania. by Jake D Mathewson, Linda van der Spek, Dunstan J Matungwa, Anna Samson, Harry L S Coleman, Ente J J Rood

“…<h4>Introduction</h4>To address problems of over- and under-treatment with preventive chemotherapy resulting in ongoing transmission of schistosomiasis, the World Health Organization (WHO) recommends targeted mass drug administration (MDA) interventions at a sub-district level. …”
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Unraveling the Anti-Cancer Mechanisms of Antibiotics: Current Insights, Controversies, and Future Perspectives by Nikolaos Nektarios Karamanolis, Dimitris Kounatidis, Natalia G. Vallianou, Krystalia Dimitriou, Eleni Tsaroucha, Georgios Tsioulos, Ioanna A. Anastasiou, Evangelos Mavrothalassitis, Irene Karampela, Maria Dalamaga

“…Furthermore, antibiotics have demonstrated the potential to enhance the efficacy of conventional modalities like chemotherapy and radiotherapy, while alleviating treatment-induced toxicities. …”
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Two rare cases of primary clear cell adenocarcinoma of the urethra: clinical experience, case report and literature review by Bohao Jiang, Jiyuan Hu, Benqiao Wang, Xujia Liu, Ling Tong, Yitong Xu, Hao Zhang

“…Case 1 undergone progression 6 months after initial treatment with transurethral resection and chemotherapy with a 15-month overall survival. In contrast, the prognosis of case 2 remained uneventful 10 months after surgery without recurrence. …”
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A Comprehensive Review on Current Knowledge and Future Potential of Topical Therapies in Breast Cancer Treatment by N. Bharathi Sai Thilagam, V.P. Karthik, R. Gnanasambandan, C. Sowmya

“…The primary treatments for breast cancer include surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapy. …”
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In Vivo Evaluation of the Combined Anticancer Effects of Cisplatin and SAHA in Nonsmall Cell Lung Carcinoma Using [18F]FAHA and [18F]FDG PET/CT Imaging by Skye Hsin-Hsien Yeh, Ming Hsien Lin, I. I. Leo Garcia Flores, Uday Mukhopadhyay, Danial Young, Kazuma Ogawa, Jeong-Hwan Jeong, William Tong, Juri G. Gelovani, Nobuyoshi Fukumitsu

“…Combining standard drugs with low doses of histone deacetylase inhibitors (HDACIs) is a promising strategy to increase the efficacy of chemotherapy. The ability of well-tolerated doses of HDACIs that act as chemosensitizers for platinum-based chemotherapeutics has recently been proven in many types and stages of cancer in vitro and in vivo. …”
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99mTc(CO)3-Labeled 1-(3-Nitropyridin-2-yl) Piperazine as Potential Radioligand for 5-HT7 Receptors by Sajjad Molavipordanjani

“…The standard treatment for GBM involves a combination of surgery, radiotherapy and chemotherapy. However, GBM tumors are highly diffuse and exhibit a significant risk of recurrence. …”
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Whole slide image based deep learning refines prognosis and therapeutic response evaluation in lung adenocarcinoma by Tao Chen, Jialiang Wen, Xinchen Shen, Jiaqi Shen, Jiajun Deng, Mengmeng Zhao, Long Xu, Chunyan Wu, Bentong Yu, Minglei Yang, Minjie Ma, Junqi Wu, Yunlang She, Yifan Zhong, Likun Hou, Yanrui Jin, Chang Chen

“…Importantly, combining TNM stage with the established model helped to distinguish subgroups of patients with high-risk stage II and stage III disease who are highly likely to benefit from adjuvant chemotherapy. Overall, our study highlights the significant value of the constructed model to serve as a complementary biomarker for survival stratification and adjuvant therapy selection for lung adenocarcinoma patients after resection.…”
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Lesser Toxicities of Belotecan in Patients with Small Cell Lung Cancer: A Retrospective Single-Center Study of Camptothecin Analogs by Yeon Hee Park, Chae Uk Chung, Bo Mi Park, Myoung Rin Park, Dong Il Park, Jae Young Moon, Hee Sun Park, Jin Hwan Kim, Sung Soo Jung, Ju Ock Kim, Sun Young Kim, Jeong Eun Lee

“…We retrospectively reviewed data from 94 patients with SCLC (with or without prior chemotherapy) who were treated using belotecan monotherapy (n=59, 188 cycles) or topotecan monotherapy (n=35, 65 cycles) between September 2003 and December 2011. …”
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Cytogenetics and Molecular Abnormalities in Pediatric Patients with Acute Myeloid Leukemia in a Referral Center in Tehran, Iran by Mahshid Heidary Sadegh, Maniya Mozafari, Mohammad Vasei, Sajjadeh Movahedinia, Marzieh Hosseini, Moeinadin Safavi

“…We aimed to evaluate the cytogenetic abnormalities of pediatric AML in association with prognosis.Method: In this retrospective cross-sectional study, 46 cases of pediatric AML, diagnosed using French-American-British (FAB) criteria, admitted to a referral center during 2018-2023, who had not yet received chemotherapy, were included. Patients were evaluated for cytogenetic alterations by bone marrow karyotyping and polymerase chain reaction molecular methods. …”
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Preparation of Iron Oxide and Titania-Based Composite, Core-Shell Populated, Nanoparticulates Material by Two-Step LASER Ablation in Aqueous Media as Antimicrobial and Anticancer A... by Hasan H. Bahjat, Raid A. Ismail, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Mohsen Al-Omar, Salman A. A. Mohammed, Riaz A. Khan

“…These NPs can also be part of combined chemotherapy in different oncological interventions, as well as a sonosensitizer in sonomagnetic heating-based therapy, especially for cancers.…”
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Positive Expression of IGFBP2 as a Novel Prognostic Biomarker for Patients with Lower-Grade Gliomas by Yanguo Li, Jiawei Fan, Zhuo Shen, Jun Zhang, Xuemei Yin, Fang Han, Wenfei Li

“…For patients with LGG overexpressing IGFBP2, radiotherapy may be a preferable choice over chemotherapy.…”
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General (hetero)polyaryl amine synthesis via multicomponent cycloaromatization of amines by Lebin Su, Jianyu Dong, Yang Shen, Shimin Xie, Shaofeng Wu, Neng Pan, Feng Liu, Qian Shang, Fangfang Cai, Tian-Bing Ren, Lin Yuan, Shuang-Feng Yin, Li-Biao Han, Yongbo Zhou

“…Due to the easy introduction of various functional units into heteropolyarylamines, multiple functionalized fluorescent dyes can be arbitrarily synthesized, which can serve as effective fluorescent probes for monitoring the pathological processes (e.g. chemotherapy-induced cell apoptosis) and studying the related disease mechanisms.…”
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Microwave Thermal Ablation in an Unusual Case of Malignant and Locally Advanced Rare Tumor of Pancreas in ASA IV Old Male Patient and Literature Review by Francesco D’Amico, Michele Finotti, Chiara Di Renzo, Alessio Pasquale, Alessandra Bertacco, Giorgio Caturegli, Gabriel E. Gondolesi, Umberto Cillo

“…The patient followed a line of chemotherapy for 6 months with a complete response for 8 months. …”
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Bellini Duct Carcinoma Misdiagnosed with Urothelial Papillary Carcinoma by Joey El Khoury, Maher Abdessater, Rami Halabi, Fadi Nasr, Johnny Boustany, Anthony Kanbar, Charbel El Hachem, Raghid El Khoury

“…Therefore, the patient required a cisplatin-gemcitabine-based chemotherapy regimen. Conclusion. BDC remains one of the rare aggressive subtypes of RCC, having a multitude of initial clinical presentations and an unfavorable prognosis. …”
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Malignant Paraganglioma With Calvarial Metastases Presenting With Recurrent Catecholamine-Induced Cardiomyopathy by Beatrice A. Brumley, MD, Run Yu, MD, PhD, Shadfar Bahri, MD, Jane Rhyu, MD

“…He developed intra-abdominal and skeletal metastatic disease by the age of 14 years and treated with surgery, chemotherapy, and radiation. After being lost to follow-up, the patient presented emergently with headache, palpitations, hypertensive crisis, type 2 non-ST-elevation myocardial infarction, and catecholamine-induced cardiomyopathy, with plasma free metanephrine level of 61.0 pg/mL (0.0-88.0 pg/mL) and elevated serum free normetanephrine level of 662.9 pg/mL (0.0-210.1 pg/mL). …”
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Successful Neurological Recovery with Multimodality Therapy without Surgery for Spinal Metastases from Advanced Gastric Cancer by Hideyuki Kinoshita, Hiroto Kamoda, Takeshi Ishii, Yoko Hagiwara, Toshinori Tsukanishi, Yusuke Amanuma, Rino Nankinzan, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Tsukasa Yonemoto

“…She was inoperable, owing to a large thrombus in the inferior vena cava; alternative multimodality treatments, including chemotherapy and radiotherapy, were administered. The paralysis and the bladder and rectal dysfunction improved considerably. …”
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The optimal treatment of invasive ductal and lobular carcinoma occurring at the same time needs to be established by Supriya Peshin, Rafi Iftekher, Rabia Iqbal, Shagun Singh, Moka Nagaishwarya

“…Multidisciplinary tumour board discussions emphasised the integration of genetic testing, including BRCA1/2 evaluation, and Oncotype DX genomic profiling to assess recurrence risk and guide adjuvant chemotherapy decisions. Recommendations included adjuvant radiation therapy for the right breast, endocrine therapy for both tumours and the incorporation of CDK 4/6 inhibitors based on recent evidence from the NATALEE trial, which demonstrated improved outcomes in high-risk, hormone receptor-positive, HER2-negative breast cancers. …”
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Nocardiosis in a Kidney-Pancreas Transplant by I. Fontana, G. Gasloli, A. Magoni Rossi, C. Bornacina, F. Dodi, M. Bertocchi, O. Soro, P. Diviacco, A. De Negri, E. Bocci, C. Ferrari, A. Giannone, Umberto Valente

“…Morganii, and a focal bronchopneumonia in the right-basal lobe resolved with elective chemotherapy. During the 50th post-operative day, an intense soft tissue inflammation localized in the first left metatarsal-phalangeal articulation occurred (Figure 1) followed by an abscess with a cutaneous fistula and extension to the almost totality of foot area. …”
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Challenges and adaptations in pancreatic cancer surgery during the COVID-19 pandemic in a high-volume center by Mohammed Al-Saeedi, Ali Ramouz, Elias Khajeh, Sakher Shraim, Alexander Werba, Georgios Polychronidis, Arianeb Mehrabi, Martin Loos

“…The rate of primary resectable tumors was significantly lower during the late pandemic phase (66% vs. 65.9% vs. 56.5%; P = 0.024), and subsequently application of neoadjuvant therapies increased in the late pandemic phase (26% vs. 25.4% vs. 33.8%; P = 0.079). The number of chemotherapy cycles were also higher during the late pandemic phase (P = 0.009). …”
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A complex case of right heart masses in a leukemia patient: a case report by Xiaoning Wang, Mahsa Fatahichegeni, Mohammad Amin Ansarian, Seifollah Ranjbarha, Juan Ren

“…Case presentation The patient was diagnosed with Acute Myeloid Leukemia and achieved complete remission following multiple chemotherapy cycles. From a leukemia treatment perspective, an allo-HSCT was needed as soon as possible. …”
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