Influence of Mesalazine on Ferroptosis-Related Gene Expression in In Vitro Colorectal Cancer Culture by Joanna Słoka, Barbara Strzałka-Mrozik, Sebastian Kubica, Ilona Nowak, Celina Kruszniewska-Rajs

“…Its fundamental treatments include surgery and chemotherapy, predominantly utilizing 5-fluorouracil (5-FU). …”
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Patients outcomes in lung adenocarcinoma transforming to small-cell lung cancer after tyrosine kinase inhibitor therapy by Shuai Wang, Yongsen Wang, Xuan Wu, Li Yang, Xiaoju Zhang

“…Conclusion Transformed SCLC exhibited poor response to primary SCLC classic chemotherapy and immunotherapy. It carries a worse prognosis. …”
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Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation by Xuan Deng, Lu Chang, Lingyu Tang, Haoqin Jiang, Xiao Xu, Xinju Zhang, Jian Chen, Liu Dong, Qianqian Xu, Ruoshui Cao, Jianbin Xiang, Ming Guan

“…High expression of GDIL in resistant CRC is associated with poor survival and hyposensitivity to chemotherapy. We demonstrate that GDIL boosted GSH levels and enhances clearance of ROS induced by platinum. …”
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Machine learning-based prognostic model for patients with anaplastic thyroid carcinoma by Yihan Sun, Da Lin, Xiangyang Deng, Yinlong Zhang

“…And we further ranked the time-dependent features according to their permutation importance and observed that surgery, radiotherapy, and chemotherapy were the most influential predictors initially. …”
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Identification of multicohort-based predictive signature for NMIBC recurrence reveals SDCBP as a novel oncogene in bladder cancer by Chen Zhang, Hubin Yin, Tinghao Li, Junrui Chen, Weiyang He, Ke Ren, Bo Li, Xudong Liu

“…Background Despite surgical and intravesical chemotherapy interventions, non-muscle invasive bladder cancer (NMIBC) poses a high risk of recurrence, which significantly impacts patient survival. …”
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Harnessing nanotechnology for cancer treatment by Jiajun Zhu, Jiajun Zhu, HaeJu Lee, HaeJu Lee, Ruotong Huang, Ruotong Huang, Jianming Zhou, Jingjun Zhang, Xiaoyi Yang, Wenhan Zhou, Wangqing Jiang, Shuying Chen

“…Nanotechnology has become a groundbreaking innovation force in cancer therapy, offering innovative solutions to the limitations of conventional treatments such as chemotherapy and radiation. By manipulating materials at the nanoscale, researchers have developed nanocarriers capable of targeted drug delivery, improving therapeutic efficacy while reducing systemic toxicity. …”
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Targeting Glutathione-S Transferase Enzymes in Musculoskeletal Sarcomas: A Promising Therapeutic Strategy by Michela Pasello, Maria Cristina Manara, Francesca Michelacci, Marilù Fanelli, Claudia Maria Hattinger, Giordano Nicoletti, Lorena Landuzzi, Pier Luigi Lollini, Annamaria Caccuri, Piero Picci, Katia Scotlandi, Massimo Serra

“…Recent studies have indicated that targeting glutathione-S-transferase (GST) isoenzymes may be a promising novel strategy to improve the efficacy of conventional chemotherapy in the three most common musculoskeletal tumours: osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. …”
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Objective Clinical and Radiological Response under Sunitinib in a Case of Thigh Hidradenocarcinoma by S. Korbi, H. Rachdi, H. El Benna, N. Mejri, Y. Berrazaga, N. Daoud, S. Labidi, H. Boussen

“…The patient was treated by 3 lines of chemotherapy, 1st by Adriamycin, 2nd by carboplatin-paclitaxel, and then 3rd by oral capecitabine, leading to a stable clinical disease but without a clinical benefit. …”
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Evaluating the Accuracy, Quality, and Readability of Online Breast Cancer Information by Elsie A. Valencia, BS, Chandler S. Cortina, MD, MS, FSSO, FACS, Adrienne N. Cobb, MD, MS, Lubna N. Chaudhary, MD, MS, Tracy Kelly, MD, Amanda L. Kong, MD, MS, FSSO, FACS

“…A qualitative analysis on 50 websites was conducted; the first 10 eligible websites for the following search terms were included: “breast cancer,” “breast surgery,” “breast reconstructive surgery,” “breast chemotherapy,” and “breast radiation therapy.” Websites were required to be in English and not intended for healthcare professionals. …”
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Mandibular (Gnathic) osteosarcoma: Narrative review emphasizing clinical, radiological, and histopathological correlation by Praveen K. Sharma, Iffath Misbah, J.H.Shazia Fathima, Ajay Lucas Rubben, Jeban Chella Bruce

“…Post-operative reconstruction is essential for restoring function and aesthetics. Chemotherapy is a critical adjunct to surgery, while radiation therapy is reserved for specific cases. …”
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Tumor-To-Tumor Metastasis of Poorly Differentiated Gastric Carcinoma to Uterine Lipoleiomyoma by Ryo Kiyokoba, Hiroshi Yagi, Hideaki Yahata, Yoshiaki Kawano, Eisuke Kaneki, Kaoru Okugawa, Kenzo Sonoda, Kiyoko Kato

“…She underwent 16 courses of TS-1/cisplatin chemotherapy, which achieved significant tumor reduction. …”
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Cerebellar metastasis from colorectal cancer: a case report by Carla E. Angulo-Rojo, Luis J. Castillo-Gaxiola, Karen Gaxiola-Gastélum, Alma M. Guadrón-Llanos, Javier A. Magaña-Gómez, Diana L. Baldenebro-Félix, Diana L. Baldenebro-Félix

“…Despite extensive treatment, including surgery and chemotherapy, the disease progressed, ultimately leading to the patient’s demise. …”
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Short‐ and Long‐Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long‐Standing Lymphedema: A Prospective Case Series by Imjai Chitapanarux, Siriarrayapa Chachvarat, Patumrat Sripan, Thienchai Pattarasakulchai, Nuttaya Pattamapaspong, Thanat Kanthawang, Montana Buntragulpoontawee

“…All of them received breast surgery and dissection of axillary lymph nodes, chemotherapy, and postoperative radiotherapy. The average duration from the onset of lymphedema to HBO treatment was 9 ± 5.92 years (range 2–17). …”
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Primary large B-cell lymphoma of the central nervous system misdiagnosed as autoimmune encephalitis: a case report by Aihui Ren, Guanwen Zeng, Riling Chen, Zhixing Cao, Wenyan Zhuo, Yubin Liang, Yubin Liang

“…The patient was then transferred for high-dose methotrexate chemotherapy but due to lack of regular follow-up, the disease progressed, resulting in cerebral herniation and respiratory failure and ultimately death. …”
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Multimodal treatments and the risk of breast cancer-related lymphedema: insights from a nationally representative cohort in South Korea by Sung Hoon Jeong, Seong Min Chun, Miji Kim, Ye Seol Lee, Jisun Kim, Ja-Ho Leigh, Yoon-Hee Choi

“…Abstract Background As the roles of chemotherapy (Chemo) and radiation therapy (Radio) in the definitive treatment of breast cancer have expanded, a broader understanding of the factors associated with breast cancer-related lymphedema (BCRL) has become increasingly essential. …”
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PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials by Samuel Pratama, Lowilius Wiyono, Martien Silviandy Setiawan, Brigitta Cindy Lauren

“…Conclusion: The addition of PARPi in the chemotherapy regimen for patients with SCLC results in increased PFS and ORR, with no difference in OS and an increased risk of TEAEs. …”
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Tumour heterogeneity and personalized treatment screening based on single-cell transcriptomics by Xinying Zhang, Jiajie Xie, Zixin Yang, Carisa Kwok Wai Yu, Yaohua Hu, Jing Qin

“…Despite advancements in anticancer drugs and optimised chemotherapy regimens that have improved cure rates for malignant tumours, the presence of tumour heterogeneity has resulted in substantial variations among patients in terms of disease progression, clinical response, sensitivity to therapy, and prognosis, posing significant challenges in attaining optimal therapeutic outcomes for each patient. …”
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Long-Term Survival in a Patient with Multiple Brain Metastases from Small-Cell Lung Cancer Treated with Gamma Knife Radiosurgery on Four Occasions: A Case Report by Ameer L. Elaimy, Sudheer R. Thumma, Andrew F. Lamm, Alexander R. Mackay, Wayne T. Lamoreaux, Robert K. Fairbanks, John J. Demakas, Barton S. Cooke, Christopher M. Lee

“…For this reason, we present the case of a 70-year-old patient who was diagnosed with multiple brain metastases from small-cell lung cancer five years ago and is currently alive following treatment with chemotherapy for the primary cancer and whole-brain radiation therapy and Gamma Knife radiosurgery on four separate occasions for the neurological cancer. …”
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Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects by Juan Iovanna, José Luis Neira

“…The presence of occult or clinical metastases at the time of diagnosis, together with the lack of effective chemotherapies, contributes to the high mortality in patients with PC. …”
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MicroRNAs in the DNA Damage/Repair Network and Cancer by Alessandra Tessitore, Germana Cicciarelli, Filippo Del Vecchio, Agata Gaggiano, Daniela Verzella, Mariafausta Fischietti, Davide Vecchiotti, Daria Capece, Francesca Zazzeroni, Edoardo Alesse

“…To preserve the genomic integrity, eukaryotic cells need a complex DNA damage/repair response network of signaling pathways, involving many proteins, able to induce cell cycle arrest, apoptosis, or DNA repair. Chemotherapy and/or radiation therapy are the most commonly used therapeutic approaches to manage cancer and act mainly through the induction of DNA damage. …”
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