YAP1::KMT2A fusion-positive sarcoma: An emerging soft tissue tumor entity with morphological features resembling a sclerosing epithelioid fibrosarcoma by Ayush Agarwal, Bharat Rekhi, Vineeta Goel, Jyoti Bajpai, Sameer Rastogi

“…SEF is characterized by EWSR1 gene rearrangement, is relatively more aggressive and shows a limited response to chemotherapy. Lately, a subset of tumors with morphological features of SEF, but lacking MUC4 immunostaining and EWSR1 gene rearrangement have been observed. …”
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Hypothyroidism Due to Thyroid Amyloidosis Simultaneously With AL Renal Amyloidosis to Give Better Idea of Association of the Two Conditions by Guan C, Liu Y, Chen R, Zhu Y

“…The patient received levothyroxine sodium tablets as replacement therapy and received chemotherapy in the hematology department. At the same time, we monitored the improvement in thyroid function and reduction in thyroid volume.Keywords: thyroid amyloidosis, hypothyroidism, renal amyloidosis, nephrotic syndrome, macroalbuminuria…”
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Antianemic Treatment of Cancer Patients in German Routine Practice: Data from a Prospective Cohort Study—The Tumor Anemia Registry by Tilman Steinmetz, Jan Schröder, Margarete Plath, Hartmut Link, Michèle Vogt, Melanie Frank, Norbert Marschner

“…Over 85% received chemotherapy. Median age was 67 years; 48% were male. …”
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Targeted therapy for cisplatin‐resistant lung cancer via aptamer‐guided nano‐zinc carriers containing USP14 siRNA by Xinmin Zhao, Xianghua Wu, Huijie Wang, Songtao Lai, Jialei Wang

“…However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying novel biomarkers to improve the diagnosis and treatment of NSCLC is important. …”
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Serum Levels of Irisin and Omentin-1 in Breast Neoplasms and Their Association with Tumor Histology by Grigorios Panagiotou, Sofia Triantafyllidou, Basil C. Tarlatzis, Eleni Papakonstantinou

“…Disease-free individuals (N = 56) and patients with histologically proven benign (N = 61) or malignant tumor (N = 96; subdivided into recently diagnosed/treatment-naïve (N = 72) and chemotherapy-treated (N = 24) subgroups) were enrolled in this study. …”
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Aggressive Disease Course of Multiple Myeloma with Concomitant ALK-Negative Anaplastic Large Cell Lymphoma: A Case Report with an Unusual Presentation by Michela Staderini, Lara Mannelli, Elisabetta Antonioli, Benedetta Puccini, Valentina Berti, Francesco Mungai, Federica Vergoni, Valentina Carrai, Luigi Rigacci, Alberto Bosi

“…The therapeutic program initially included chemotherapy (cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone; CHOEP), radiotherapy on the leg, bortezomib, and then consolidation with autologous hematopoietic stem cell transplantation. …”
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Synergistic anticancer effects of cisplatin and phenolic aglycones of the aerial part of Rumex dentatus L. in tongue squamous cell carcinoma: insights from network pharmacology and... by Amany E. Ragab, Ghada M. Al-Ashmawy, Sherin R. El Afify, Ola A. El-Feky, Amera O. Ibrahim

“…Cisplatin is the standard chemotherapy for OSCC, but resistance often reduces its efficacy, necessitating new treatments with fewer side effects. …”
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Infantile Extracranial Rhabdoid Tumor of the Scalp by Sura Al Rawabdeh, Deifallah Alsharari, Hayat Khasawneh, Ola M. Al Waqfi, Qamar Yaser Malabeh, Hiathem Abu Alhaija, Raed Mohammad Aljubour, Hamzeh M. Alkhawaldeh

“…After tumor excision, the patient was referred to pediatric oncology to receive chemotherapy. Experience with scalp extracranial rhabdoid tumors is limited. …”
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Retroperitoneal Soft Tissue Sarcoma and Kidney Autotransplantation: A Case Report by S. N. Hakkesteegt, C. A. J. Oudmaijer, L. J. Jeletich, J. Sprakel, H. J. A. N. Kimenai, D. J. Grünhagen

“…After unsuccessful neoadjuvant chemotherapy, she underwent an en‐bloc resection and subsequent autotransplantation. …”
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Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value. by Ann Mari Rosager, Mia D Sørensen, Rikke H Dahlrot, Steinbjørn Hansen, David L Schonberg, Jeremy N Rich, Justin D Lathia, Bjarne W Kristensen

“…Treatment with radio- and chemotherapy has increased survival making prognostic biomarkers increasingly important. …”
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Expression of MxA in esophageal cancer cell lines can influence sensitivity to chemotherapeutic agents but this does not require apoptosis by R. M. Hayes, T. R. O'Donovan, S. L. McKenna

“…Collectively these data indicate that MxA can promote resistance to chemotherapy, but this does not always correspond with effects on apoptosis. …”
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Multicellular model of neuroblastoma proposes unconventional therapy based on multiple roles of p53. by Kenneth Y Wertheim, Robert Chisholm, Paul Richmond, Dawn Walker

“…Over half of all high-risk cases are expected to succumb to the disease even after chemotherapy, surgery, and immunotherapy. Although the importance of MYCN amplification in this disease is indisputable, the mechanistic details remain enigmatic. …”
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Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases by Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime

“…PPARγ ligands show great promise in moderating lung inflammation, as antiproliferative agents in combination to enhance standard chemotherapy in lung cancer and as treatments for pulmonary fibrosis, a progressive fatal disease with no effective therapy. …”
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Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects by Boyun Gou, Guoqing Chen, Shicong Huang, Na Ning, Qian Gu, Shuai Duan, Yuhua Du, Yi Nan, Ling Yuan

“…Although there are effective treatments such as radiotherapy and chemotherapy for cancers, they are often accompanied by serious side effects. …”
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Association of JMJD2B and Hypoxia-Inducible Factor 1 Expressions with Poor Prognosis in Osteosarcoma by Xujian Liu, Qianqian Zhang, Yi Zhao, Jianjun Xun, Hongzeng Wu, Helin Feng

“…JMJD2B and HIF1 expression levels were both significantly associated with Enneking stage, distant metastasis, and neoadjuvant chemotherapy, and the JMJD2B and HIF1 expressions were positively correlated (p<0.001, R=0.752). …”
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Correlation of Oncotype DX Recurrence Score with Histomorphology and Immunohistochemistry in over 500 Patients by Matthew G. Hanna, Ira J. Bleiweiss, Anupma Nayak, Shabnam Jaffer

“…The RR is divided into low (0–17), intermediate (18–30), and high (31) to predict chemotherapy benefit. Our goal was to determine the association between histomorphology, immunohistochemistry, and RR. …”
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Three Cases of Pseudo-Meigs’ Syndrome Secondary to Ovarian Metastases from Colorectal Cancer by Yuta Yamamoto, Yusuke Miyagawa, Takehito Ehara, Makoto Koyama, Satoshi Nakamura, Daisuke Takeuchi, Futoshi Muranaka, Masato Kitazawa, Shinichi Miyagawa

“…In case 3, the patient developed a massive pleural effusion and ascites coincident with a rapid enlargement of ovarian tumor after resection and adjuvant chemotherapy for rectal cancer. In all cases, pleural effusions and/or ascites resolved and general conditions and daily activities of the patients improved after oophorectomy. …”
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Inosine monophosphate dehydrogenase 2 (IMPDH2) modulates response to therapy and chemo-resistance in triple negative breast cancer by Tatiane da Silva Fernandes, Bryan M. Gillard, Tao Dai, Jeffrey C. Martin, Kanita A. Chaudhry, Scott M. Dugas, Alyssa A. Fisher, Pia Sharma, RongRong Wu, Kristopher M. Attwood, Subhamoy Dasgupta, Kazuaki Takabe, Spencer R. Rosario, Anna Bianchi-Smiraglia

“…Abstract Triple negative breast cancer (TNBC) is one of the deadliest subtypes of breast cancer, whose high frequency of relapse is often due to resistance to chemotherapy. Here, we identify inosine monophosphate dehydrogenase 2 (IMPDH2) as a contributor to doxorubicin resistance, in multiple TNBC models. …”
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Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery by Jessica L. Woodman, Min Sung Suh, Jianxing Zhang, Yuvabharath Kondaveeti, Diane J. Burgess, Bruce A. White, Glenn D. Prestwich, Liisa T. Kuhn

“…CMHA stabilized particles (nCaPCMHA) were loaded with the chemotherapy drug cis-diamminedichloroplatinum(II) (CDDP) to form nCaPCMHACDDP. …”
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Risk Factors Associated with Helminthic Intestinal Infection in Lurambi Subcounty, Kakamega, Kenya by Ruth W. Kiiti, Elizabeth N. Omukunda, Jackson C. Korir

“…Conclusion. Preventive chemotherapy and proper hygienic and sanitation practices should be integrated to achieve elimination of STH and Schistosoma mansoni in Lurambi Subcounty and at large in Kenya.…”
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