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9621
Executioner caspases degrade essential mediators of pathogen-host interactions to inhibit growth of intracellular Listeria monocytogenes
Published 2025-01-01“…To establish infections in a human host, Listeria monocytogenes deploy virulence mediators, including membranolytic listeriolysin O (LLO) and the invasion associated protein p60 (Iap), allowing phagosomal escape, intracellular replication and cell-to-cell spread. Here, by means of chemical and genetical modifications, we show that the executioner caspases-3 and -7 efficiently inhibit growth of intracellular Listeria monocytogenes in host cells. …”
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9622
Essential Oils from Citrus Peels Promote Calcium Overload-Induced Calcicoptosis in U251 Cells
Published 2024-12-01“…Citrus peel essential oils (CPEOs) have demonstrated substantial medicinal potential for glioblastoma treatment because of their extensive antitumor effects, low potential for drug resistance, and ability to cross the human blood–brain barrier. In this study, the chemical compositions of five CPEOs were analyzed via gas chromatography–mass spectrometry (GC-MS). …”
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9623
The feasibility study of natural pigments as food colorants and seasonings pigments safety on dried tofu coloring
Published 2018-09-01“…In addition, researches showed that chemical soy sauce produces a trace of methylglyoxal (MGO) in the manufacturing process, which is related to diseases such as oxidative stress, diabetes, and cognitive deterioration. …”
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9624
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9625
The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways
Published 2025-01-01“…This study investigated the effect of DOCK5 on bone regeneration using C21, a DOCK5 chemical inhibitor, and Dock5-deficient mice. Osteoblast differentiation and bone regeneration were analyzed using bone marrow mesenchymal stem cells (BMSCs) and various animal models. …”
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9626
Tetramycin ameliorates tebuconazole·azoxystrobin to control leaf spot and viral diseases of Taizishen
Published 2025-02-01“…This study highlights the combined application of low-dosage tebuconazole·azoxystrobin and tetramycin as a practicable measure for controlling leaf spot and viral diseases in Taizishen, promoting its resistance, growth, and quality, as well as reducing chemical pesticide application.…”
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9627
Characterization of Cantal and Salers Protected Designation of Origin Cheeses Based on Sensory Analysis, Physicochemical Characteristics and Volatile Compounds
Published 2025-01-01“…The provenance of milk from two dairy cow breeds (<i>Salers</i> and <i>non-Salers</i>) was discussed sensorially and chemically for each cheese sample and for each cheese category. …”
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9628
The Oil-Bearing Strata of Permian Deposits of the Ashal’cha Oil Field Depending on the Content, Composition, and Thermal Effects of Organic Matter Oxidation in the Rocks
Published 2020-01-01“…According to the molecular mass distribution of alkanes of normal and isoprenoid structure, extracts from rocks are differentiated according to three chemical types of oil: type A1, in which n-alkanes of composition C14 and above are present, and types A2 and B2, in which n-alkanes are destroyed to varying degrees by processes microbial destruction, which indicates a different intensity of biochemical processes in productive strata of Permian sediments. …”
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9629
Proinflammatory Effects of Diesel Exhaust Nanoparticles on Scleroderma Skin Cells
Published 2014-01-01“…The effects of carbon-based nanoparticulate collected at the exhaust of newer (Euro 5) and older (Euro 4) diesel engines on SSc skin keratinocytes and fibroblasts were evaluated in vitro by assessing the mRNA expression of inflammatory cytokines (IL-1α, IL-6, IL-8, and TNF-α) and fibroblast chemical mediators (metalloproteases 2, 3, 7, 9, and 12; collagen types I and III; VEGF). …”
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9630
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9631
Simultaneous Determination of Cr, As, Se, and Other Trace Metal Elements in Seawater by ICP-MS with Hybrid Simultaneous Preconcentration Combining Iron Hydroxide Coprecipitation an...
Published 2018-01-01“…Moreover, for speciation analyses of Cr, As, and Se, the pH dependence on recovery for the different chemical forms of Cr, As, and Se was investigated. …”
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9632
<i>Lomatium</i> Species of the Intermountain Western United States: A Chemotaxonomic Investigation Based on Essential Oil Compositions
Published 2025-01-01“…<i>triternatum</i> were too variable to confidently assign a chemical type. The major components in the <i>L. nudicaule</i> essential oils were β-phellandrene (16.0–45.7%), (<i>Z</i>)-ligustilide (5.6–47.1%), (<i>E</i>)-β-ocimene (3.3–9.9%), and δ-3-carene (0.2–12.6%). …”
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9633
First evidence of sinter and travertine in Cameroon: fault reactivation and geothermal implications
Published 2023-09-01“…The europium anomalies values (Eu/Eu*: 0.54–1.78) indicate the temperature variation of precipitated deposits related to distance of the deep hot water flow. The chemical compositions of the lithofacies show the diversity of the spring deposits related to complex phenomena of internal migration of mineralized hot water and the tectonic controls during the Precambrian fault reactivations.…”
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9634
The <i>MCPH7</i> Gene Product STIL Is Essential for Dendritic Spine Formation
Published 2025-01-01“…FRET experiments showed that Rac activation is impaired in STIL knockdown neurons. Chemical long-term potentiation, which triggers Rac activation, promoted STIL accumulation in the spine and its association with ARHGEF7. …”
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9635
Application of Flour Blends from Modified Cassava and Suweg Flours in Gluten-Free Steamed Brownies
Published 2024-05-01“…The results showed that the MCF to SF ratio significantly influenced various parameters of flour blends, such as chemical compositions, color characteristics, pasting, and functional properties. …”
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9636
Solar‐Driven Hydrogen Peroxide Production via BiVO4‐Based Photocatalysts
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9637
Ethnotherapeutic Uses and Phytochemical Composition of Physalis peruviana L.: An Overview
Published 2021-01-01“…P. peruviana plays an essential role in managing diseases in some countries and is rich in chemical compounds, which need to be isolated and investigated pharmacologically before clinical trials.…”
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9638
Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases
Published 2025-01-01“…Additionally, hydroxyapatite-based nanocomposites enhance mechanical properties and bioactivity through chemical bonding with the polymer matrix. These advancements show significant potential in treating various skin conditions, including wounds, infections, cancer, and tissue engineering. …”
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9639
Analysis of environmental health risks from exposure to polyethylene terephthalate microplastics in refilled drinking water
Published 2023-11-01“…If they build up in the body, microplastics may have harmful consequences, including organ inflammation, internal or external damage, and chemical alteration of plastics that have already entered the body.CONCLUSION: Some measures of risk management that can be performed are to reduce the concentration of risk agents if the pattern and timing of consumption cannot be changed, reduce the consumption pattern (intake rate) if the concentration of risk agents and the time of consumption cannot be changed, and reduce the contact time if the risk agent concentration and consumption pattern cannot be changed.…”
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9640