A paper-based HPV E7 oncoprotein assay for cervical precancer detection at the point of care by Chelsey A. Smith, Sai Paul, Karen E. Haney, Sonia G. Parra, Meaghan Bond, Leticia López, Mauricio Maza, Juan Felix, Preetha Ramalingam, Pablo Escobar, Philip E. Castle, Kathleen M. Schmeler, Rebecca R. Richards-Kortum

“…Abstract Cervical cancer, while preventable through screening and treatment of cervical precancer, remains a global challenge with a disproportionately high burden of disease in resource-limited settings, especially in low- and middle-income countries (LMICs). …”
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Biological Effect of Organically Coated Grias neuberthii and Persea americana Silver Nanoparticles on HeLa and MCF-7 Cancer Cell Lines by Lizeth Salazar, María José Vallejo López, Marcelo Grijalva, Luis Castillo, Alexander Maldonado

“…The aim of this study was to assess the biological effect of organically coated Grias neuberthii (piton) fruit and Persea americana (avocado) leaves nanoparticles (NPs) on cervical cancer (HeLa) and breast adenocarcinoma (MCF-7) cells with an emphasis on gene expression (p53 transcription factor and glutathione-S-transferase GST) and cell viability. …”
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Programmable Multiplexed Nucleic Acid Detection by Harnessing Specificity Defect of CRISPR‐Cas12a by Xin Guan, Rui Yang, Jiongyu Zhang, Jeong Moon, Chengyu Hou, Chong Guo, Lori Avery, Danielle Scarola, Daniel S. Roberts, Rocco LaSala, Changchun Liu

“…With the assay, 14 high‐risk human papillomavirus (HPV) subtypes are simultaneously detected, collectively responsible for 99% of cervical cancer cases, with attomolar sensitivity. Specifically, the assay not only distinguishes HPV16 and HPV18, the two most common subtypes but also detects 12 other high‐risk pooled HPV subtypes. …”
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Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities by Deepak Kumar Shrestha, Akash Budha Magar, Manisha Bhusal, Rabina Baraili, Ishwor Pathak, Pusp Raj Joshi, Niranjan Parajuli, Khaga Raj Sharma

“…The nanoparticles also exhibit potent cytotoxicity with IC50 of 76.82 ± 1.67 μg/mL against cervical cancer cell lines. Both nanoparticles and aqueous extract were mildly toxic towards the brine shrimp nauplii with the lowest LC50 being 661.80 ± 64.21 μg/mL for the aqueous extract. …”
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The Quebec Association of Gastroenterology Position Paper on Colorectal Cancer Screening - 2003 by AN Barkun, G Jobin, G Cousineau, S Dubé, R Lahaie, P Paré, B Stein, R Wassef

“…Evidence suggests that screening can reduce mortality rates and the cost effectiveness of a program compares favourably with initiatives for breast and cervical cancer. The objectives of the Association des gastro-entérologues du Québec Task Force were to determine the need for a policy on screening for colorectal cancer in Quebec, to evaluate the testing methods available and to propose one or more of these alternatives as part of a formal screening program, if indicated. …”
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Transcriptome profiling revealed multiple circadian rhythm-related genes associated with common gynecological cancers by Lan Peng, Meiping Jiang, Kangming Li, Shuhui Yu, Chunfang Zhao, Lan Zhang, Lan Li

“…However, the roles of circadian rhythm-related genes (CRRGs) in cervical cancer (CC) and other common gynecologic cancers remain unclear.MethodsThe transcriptome data and clinical information related to CC and other common gynecologic cancers were extracted from the UCSC Xena and Gene Expression Omnibus (GEO) databases. …”
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Oleuropein in olive leaf, branch, and stem extracts: stability and biological activity in human cervical carcinoma and melanoma cells by Benčić Đani, Barbarić Monika, Mornar Ana, Klarić Daniela Amidžić, Brozovic Anamaria, Dabelić Sanja, Fadljević Mihaela, Marković Ana Karković

“…The biological activity of extracts was determined on cervical cancer (HeLa), melanoma (A375), metastatic melanoma (A375M) tumor cell lines, and on spontaneously immortalized cell line of keratinocytes (HaCaT), using the MTT assay. …”
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Knowledge, Attitudes, and Practices in Relation to Reproductive Health Among Young Albanian Women by Alketa Zazo, Eliona Kulluri, Enxhi Vrapi

“…RESULTS: Women, participating in this study, appeared to be well-informed regarding the risk factors associated with cervical cancer, yet only 32.7% had carried out a Pap-smear test. …”
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Radiation-induced impacts on mitochondrial DNA and the transgenerational genomic instability by Ryosuke Seino, Haruka Kubo, Kai Nishikubo, Hisanori Fukunaga

“…In this study, we investigated the radiation-induced impacts on mitochondrial DNA in vitro and in vivo, as well as the transgenerational inheritance. Methods: Human cervical cancer HeLa cells and telomerase-immortalized normal fibroblast BJ1-hTERT cells were exposed to X-rays at 0.5–8 Gy. …”
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A Global Survey of Self-Reported Cancer Screening Practices by Health Professionals for Kidney Transplant Candidates and Recipients by Nida Saleem, Nida Saleem, Nida Saleem, Wai H. Lim, Wai H. Lim, Jacqueline H. Stephens, Jacqueline H. Stephens, Annabelle Wilson, Billie Bonevski, Allison Jaure, Allison Jaure, Armando Teixeira-Pinto, Armando Teixeira-Pinto, Eleonora Dal Grande, Eleonora Dal Grande, Martin Howell, Martin Howell, Farzaneh Boroumand, Farzaneh Boroumand, Anita van Zwieten, Anita van Zwieten, Chandana Guha, Chandana Guha, Nicole Scholes-Robertson, Nicole Scholes-Robertson, Steven J. Chadban, Steven J. Chadban, Carmel M. Hawley, Carmel M. Hawley, Jonathan C. Craig, Jeremy R. Chapman, Danyal Hassan, Greg Knoll, Greg Knoll, Naoka Murakami, Germaine Wong, Germaine Wong, Germaine Wong

“…We received 97 responses, and most were nephrologists (70%), and around 80% recommended breast, colorectal, and cervical cancer screening for kidney transplant candidates and recipients. …”
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Expression and Significance of Immune Checkpoints in Clear Cell Carcinoma of the Uterine Cervix by Liju Zong, Qianqian Zhang, Yuncan Zhou, Yujia Kong, Shuangni Yu, Jie Chen, Youzhong Zhang, Yang Xiang

“…The purpose of this study was to investigate the expression levels of the immune checkpoint proteins, programmed cell death-ligand 1 (PD-L1), B7-H3, B7-H4, and V-domain Ig suppressor of T cell activation (VISTA), as well as the significance thereof, in clear cell carcinoma (CCC) of the cervix (a rare histological subtype of cervical cancer). We also compared the expression statuses of these biomarkers in cervical CCCs with those in cervical squamous cell carcinomas (SCCs). …”
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Prevalence and characteristics of HPV vaccine hesitancy among parents of adolescent females across Saudi Arabia by Sahar Othman, Ranya Ghamri, Wala Alhamadah, Anwaar Alsatty, Dhuha Khesfaty, Ohoud Alghamdi, Ragad Arbaein, Alaa M. Baglagel, Jumana Khayyat, Bushra Almalki

“…PurposeVaccination against human papillomavirus (HPV) is pivotal in preventing HPV-related diseases, including cervical cancer. However, vaccine hesitancy and their related factors among parents of adolescent females present a significant obstacle to achieving high vaccination rates. …”
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Prevalence of non-vaccine high-risk HPV cervical infections in vaccinated women: a systematic review and meta-analysis by Glauciane Resende do Nascimento, Ana Carolina da Silva Santos, Nayara Nascimento Toledo Silva, Nathalia Sernizon Guilmarães, Angélica Alves Lima, Wendel Coura-Vital

“…Abstract Background Human Papillomavirus (HPV) is the most common sexually transmitted lower genital tract infection worldwide and the main etiological factor of cervical cancer (CC). Since 2006, vaccines have been implemented to reduce CC-related morbidity and mortality. …”
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Practices regarding human Papillomavirus counseling and vaccination in head and neck cancer: a Canadian physician questionnaire by Scott Anderson, Andre Isaac, Caroline C. Jeffery, Joan L. Robinson, Daniela Migliarese Isaac, Christina Korownyk, Vincent L. Biron, Hadi Seikaly

“…While the association between HPV infection and cervical cancer is widely understood, its relation to HNC is less well known. …”
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Healthcare Costs and Resource Use Associated With Cervical Intraepithelial Neoplasia and Cervical Conization: A Retrospective Study of German Statutory Health Insurance Claims Data by Anna-Janina Stephan, Miriam Reuschenbach, Kunal Saxena, Vimalanand S. Prabhu, Christian Jacob, Kim M. Schneider, Wolfgang Greiner, Regine Wölle, Monika Hampl

“…High-grade CIN (CIN2/CIN3) may develop from persistent HPV infection and progress to cervical cancer if left untreated. Management of CIN includes conservative surveillance or ablation and excision by conization. …”
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Reproductive health literacy scale: a tool to measure the effectiveness of health literacy training by Maha Rauf, Zahra Goliaei, Lana Machta, Jenny Chang, Heike Thiel de Bocanegra

“…The identified items were collected and adapted as a single scale with three domains: (a) general health literacy, measured with HLS-EU-Q6, (b) digital health literacy, measured with eHEALS, and (c) reproductive health literacy, measured through a composite of the Cervical Cancer Literacy Assessment Tool (C-CLAT) and the Refugee Reproductive Health Network (ReproNet) postpartum literacy scale. …”
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Diagnostic accuracy of human papillomavirus testing on self-collected samples among women referred for colposcopy by ChunX Yan, Jiong Ma, Xia Zheng, Jing Shu, XiaoJ Wang, XiaoY Chen, Feng Gao, XiaoQ Li, ShanQ M, LongM Huang, XiaoT Yu, XueJ Chen

“…It may be an alternative option for cervical cancer screening. Additional studies are still required to substantiate this issue.…”
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Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraep... by Fei Chen, Jinghe Lang, Peter Hillemanns, Youzhong Zhang, Zoltán Novák, Long Sui, Ling Han, Christian Dannecker, Ctirad Mokráš, Zhixue You

“…Introduction High-risk human papilloma virus (HPV)-associated cervical cancer is the fourth most common cancer in women worldwide. …”
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Black Trumpet, Craterellus cornucopioides (L.) Pers.: Culinary Mushroom with Angiotensin Converting Enzyme Inhibitory and Cytotoxic Activity by Jelena Radović, Aleksandra Leković, Ana Tačić, Margarita Dodevska, Tatjana Stanojković, Tijana Marinković, Čedomir Jelić, Tatjana Kundakovic-Vasović

“…Cyclohexane and dichloromethane extracts expressed significant cytotoxic activity against selected cell lines, human epithelial cervical cancer cells (HeLa), adenocarcinomic human alveolar basal epithelial cells (A549), colorectal cancer cells (LS174) and normal MRC-5 human embryonic lung fibroblast cells (IC50 of 78.3–155.6 μg/mL). …”
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Design and development of novel 1,2,3-triazole chalcone derivatives as potential anti-osteosarcoma agents via inhibition of PI3K/Akt/mTOR signalling pathway by Su Qing, Xu Baolin, Tian Zhoubin, Gong Ziling

“…The three most active compounds: 4e (N-(4-(3-(1-(4-bromophenyl)-1H-1,2,3-triazol-4-yl)acryloyl)phenyl)-4-nitrobenzamide), 4f (N-(4-(3-(1-(4-bromophenyl)-1H-1,2,3-triazol-4-yl)acryloyl)phenyl)-4-chlorobenzamide) and 4g (4-bromo-N-(4-(3-(1-(4-bromophenyl)-1H-1,2,3-triazol-4-yl)acryloyl)phenyl)benzamide), were evaluated for anticancer activity against human OS cancer cell line (MG-63), liver cancer cell line (HepG2), lung cancer cell line (A549) and cervical cancer (HeLa), using MTT assay. Among the tested series, compound 4e showed a better inhibitory profile than gedatolisib against PI3K and was approximately comparable to that of gedatolisib against mTOR. …”
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