Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin by Togbemabou Primous Martial Godjedo, Alidehou Jerrold Agbankpe, Moussiliou Noël Paraiso, Tamegnon Victorien Dougnon, Marie Hidjo, Lamine Baba-Moussa, Honore Bankole

“…This is a prospective, descriptive, analytical study, and it took place from 2016 to 2018. Cerebrospinal fluid (CSF) samples were taken after the identification of meningitis cases. …”
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Macrophage activation syndrome in a patient with systemic lupus erythematous triggered by tuberculous meningitis by Noura Alowais, Noura Zamani, Faisal Elbadawi, Hassan Ahmed, Pankhi Dutta, Aesha Sharif

“…She was ultimately diagnosed with SLE flare complicated by MAS secondary to TBM in view of persistent fever, neuropsychiatric symptoms, hyperferritinemia and hypertriglyceridemia, supported by bone marrow aspiration findings, a tuberculosis (TB) positive contact and supporting cerebrospinal fluid analysis suggestive of TBM. She was immediately started on pulse doses of steroids and anti-tuberculosis medications in which significant clinical improvement was observed. …”
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Safety and Feasibility of Internal Fixation Using Bioabsorbable Versus Titanium Materials for Short‐Level Lamina Reimplantation: A Comparative Clinical Study by Dingbang Chen, Jinhan Song, Luosheng Zhang, Xin Gao, Quan Huang, Xinghai Yang

“…Fisher exact, Chi‐square, or rank sum test were used for categorical variables, and t‐test was used for continuous variables to distinguish differences between groups. Results Cerebrospinal fluid leak was the most common complication, with no difference between the two groups (12.9% vs. 19.4%, p = 0.366). …”
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Glymphatic system clearance and Alzheimer’s disease risk: a CSF proteome-wide study by Natalia Cullell, Giovanni Caruana, Andrea Elias-Mas, Ariane Delgado-Sanchez, Cristina Artero, Maria Teresa Buongiorno, Marta Almería, Nicola J. Ray, Sonia A. L. Correa, Jerzy Krupinski

“…In Stage 1 (evaluated in the Cohort 1 of aMCI participants (n = 11)), we correlated the levels of 7K cerebrospinal fluid (CSF) proteins (estimated by SOMAscan) with GS health in 78 Freesurfer-segmented brain regions of interest (ROIs). …”
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Masticatory muscle changes on magnetic resonance imaging of dogs with Neospora caninum compared to meningoencephalitis of unknown origin by Jessica Zilli, Kathryn Fleming, Chloe Fisher, Chloe Fisher, Tim Sparks, Tom Harcourt-Brown, Edward Ives

“…Within the neosporosis group, dogs with masticatory muscle lesions had significantly higher cerebrospinal fluid WBC counts (p = 0.017) and protein concentrations (p = 0.025) compared to those without muscle changes. …”
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Radiological markers of CSF α-synuclein aggregation in Parkinson’s disease patients by Amgad Droby, Avital Yoffe-Vasiliev, Daniel Atias, Kyle B. Fraser, Omar S. Mabrouk, Nurit Omer, Anat Bar-Shira, Mali Gana-Weisz, Orly Goldstein, Moran Artzi, Dafna Ben Bashat, Roy N. Alcalay, Avi Orr-Urtreger, Julia C. Shirvan, Jesse M. Cedarbaum, Nir Giladi, Anat Mirelman, Avner Thaler

“…This study investigated the association between cerebrospinal fluid (CSF) radiological measures in 41 PD patients (14 iPD, 14 GBA1-PD, 13 LRRK2-PD) and 14 age-and-sex-matched healthy controls. …”
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Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…Methods This was a randomized, placebo-controlled, double-blind study (EudraCT No. 2022-002868-76), investigating safety/tolerability, pharmacokinetics, and pharmacodynamics (including blood and cerebrospinal fluid biomarkers). Participants received 5 or 10 mg/kg NX210c or placebo (10-min infusion) thrice weekly for 4 weeks in an ascending dose fashion. …”
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Symptomatic neurosyphilis in HIV-negative patients: a retrospective cohort study by Qiaoer Chen, Qiaoer Chen, Weiqi Wu, Lu Wang, Honghong Huang, Lingxing Wang

“…Overall, 134 (94.4%) patients had elevated cerebrospinal fluid (CSF) cell counts, 113 (79.6%) had elevated protein levels, and 22/133 (16.5%) had elevated intracranial pressure. …”
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Anterior skull base reconstruction using nasoseptal flap: cadaveric feasibility study and clinical implication [SevEN-001] by Kyoung Su Sung, Jaejoon Lim, Minkyun Na, Sanghun Lee, Ju-Seong Kim, Je Beom Hong, Chang-Ki Hong, Ju Hyung Moon

“…Abstract Background Pedicled nasoseptal flap (PNSF) has significantly improved the surgical outcomes of endoscopic endonasal approach (EEAs) by reducing cerebrospinal fluid (CSF) leakage. The purpose of this study is to assess the feasibility of using a PNSF for anterior skull base (ASB) reconstruction and to describe a method to compensate for a short flap based on our results. …”
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The MRI-based vertebral bone quality score is a predictor of pedicle screw loosening following instrumented posterior lumbar fusion by Yung-Hsueh Hu, Jian-Hong Chou, Yu-Cheng Yeh, Ming-Kai Hsieh, Tsung-Ting Tsai, Wen-Jer Chen, Lih-Hui Chen, Po-Liang Lai, Chi-Chien Niu

“…The score was calculated with the median signal intensity value of L1 to L4 divided by the signal intensity value of cerebrospinal fluid at the L3 level. Univariate analysis and multivariate binary logistic regression analysis were performed. …”
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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

“…In addition to its role in disease pathology, CHI3L1 has emerged as a promising biomarker for the diagnosis and monitoring of brain disorders. Elevated cerebrospinal fluid (CSF) levels of CHI3L1 have been linked to disease severity and cognitive decline, particularly in AD and MS, highlighting its potential for clinical diagnostics. …”
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Optimal trajectory of the neuroendoscope for third ventricle pavement access by Joana Sousa, Susana Maria Silva, Susana Maria Silva, Hélio Alves, Bruno Carvalho, Bruno Carvalho, José Maria Sousa, Manuel J. Ferreira-Pinto, Manuel J. Ferreira-Pinto, Manuel J. Ferreira-Pinto, Manuel J. Ferreira-Pinto, José Paulo Andrade, José Paulo Andrade

“…Background and aimEndoscopic Third Ventriculostomy (ETV) is used to treat hydrocephalus, an abnormal cerebrospinal fluid accumulation in brain ventricles. By defining a new trajectory and entry point interval, we aim to establish a standardized approach for FreeHand ETV, a vital technique when specialized tools are unavailable, or during emergencies.Methods187 MRIs were analyzed, with 30 having hydrocephalus. …”
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Neurocognitive Impairment in HIV-Infected Naïve Patients with Advanced Disease: The Role of Virus and Intrathecal Immune Activation by Monica Airoldi, Alessandra Bandera, Daria Trabattoni, Benedetta Tagliabue, Beatrice Arosio, Alessandro Soria, Veronica Rainone, Giuseppe Lapadula, Giorgio Annoni, Mario Clerici, Andrea Gori

“…Cross-sectional and longitudinal analysis of HIV RNA, proinflammatory cytokines (IL-6, IL-10, INF-γ, TNF-α, TGF-β1, and TGF-β2) and chemokines (MIP-1α, MIP-1β, and MCP-1) in plasma and cerebrospinal fluid (CSF) of HIV-infected patients with CD4 <200/μL. …”
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Streptococcus suis-associated neonatal meningitis and sepsis: characterization, antimicrobial resistance, and public health implications by Giovanna Fusco, Rubina Paradiso, Lorena Cardillo, Maria Antonia Salvia, Saveria Dodaro, Veronica Del Monaco, Gianfranco Scarpelli, Francesca Greco, Antonio Rinaldi, Lorella Barca, Stefania Ambrogio, Antonio Limone, Esterina De Carlo, Giorgia Borriello

“…Streptococcus (S.) suis was isolated from cerebrospinal fluid and blood. Next-generation sequencing revealed that the strain was serotype 2 sequence type 1, and contained the ermB and tet(W) genes, which are responsible for resistance to macrolides and tetracycline, along with several pilus-associated genes and 20 virulence factors. …”
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Clinical effect analysis of posterior longitudinal ligament resection during anterior cervical discectomy and fusion in the treatment of cervical spondylotic myelopathy by NIU Hai‐ying, MENG Xiang‐yu, ZUO Shan‐shan, SUN Xiao‐li, LI Yan, LIU Hong‐lei

“…There were 30 patients (78.95%) experienced transient symptoms, including dysphagia, pharyngeal pain and drinking cough, 15 patients (39.47%) reported symptoms of hoarseness, 3 patients (7.89%) experienced a transient decrease in muscle strength in the left upper limb, and one patient (2.63%) had cerebrospinal fluid leakage. Notably, no patients exhibited incomplete healing of the incision or infection. …”
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Analysis of risk factors for acute cerebral infarction in patients with intracranial tuberculosis by Xiao-Shan Huang, Xiao-Wei Qiu, An-Long Wang, Fei He, Yi-Jing Wang

“…Clinical data, cerebrospinal fluid (CSF) examinations, and imaging features (such as hydrocephalus, cerebral arteritis, and meningeal thickening) were compared between the two groups. …”
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Cardiorespiratory dynamics in the brain: Review on the significance of cardiovascular and respiratory correlates in functional MRI signal by Mahathi Kandimalla, Seokbeen Lim, Jay Thakkar, Sannidhi Dewan, Daehun Kang, Myung-Ho In, Hang Joon Jo, Dong Pyo Jang, Zuzana Nedelska, Maria I. Lapid, Yunhong Shu, Cheon-Pyung, Petrice M. Cogswell, Val J. Lowe, Jeyeon Lee, Hoon-Ki Min

“…We also discuss the complexities of distinguishing these signals from neuronal activity in fMRI data, given their significant contribution to signal variability and interactions with cerebrospinal fluid (CSF). Recognizing the influence of these cardiorespiratory dynamics is crucial for improving the interpretation of fMRI data, shedding light on heart-brain and respiratory-brain connections, and enhancing our understanding of circulation, oxygen delivery, and waste elimination within the brain.…”
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Fever, Myositis, and Paralysis: Is This Inflammatory Myopathy or Neuroinvasive Disease? by Aneeta R. Kiran, Richard A. Lau, Kim M. Wu, Andrew L. Wong, Philip J. Clements, Emil R. Heinze

“…EMG/NCS showed sensorimotor axonal polyneuropathy and the cerebrospinal fluid was positive for IgM and IgG WNV antibodies. …”
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Cortical Reorganization following Injury Early in Life by Moran Artzi, Shelly Irene Shiran, Maya Weinstein, Vicki Myers, Ricardo Tarrasch, Mitchell Schertz, Aviva Fattal-Valevski, Elka Miller, Andrew M. Gordon, Dido Green, Dafna Ben Bashat

“…Children with hemiplegia demonstrated reduced total cerebral volume, with increased cerebrospinal fluid (CSF) and reduced total white matter volumes, with no differences in total gray matter volume, compared to typically developing children. …”
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Safety and Feasibility of Repeated Intrathecal Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells in Patients with Neurological Diseases by Kuang Pan, Lingna Deng, Peiying Chen, Qingxia Peng, Jingrui Pan, Yanfeng Wu, Yidong Wang

“…Adverse events, cerebrospinal fluid (CSF) test results, clinical symptoms, physical examination, and haematological and imaging examinations were used to assess the safety and feasibility of the treatment. …”
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