Isolated Central Nervous System Infiltrated and Progressed to Acute Myeloid Leukemia from Chronic Myeloid Leukemia with e1a3 BCR-ABL1 Transcript: A Rare Case Report and Literature... by Qiang X, Wen Q, Li J, Chen S, Tao T, Zhang H, Wang P, Peng X, Feng Y, Zhang X

“…Subsequent bone marrow analysis and flow cytometry detection of cerebrospinal fluid indicated that the patient had entered the blast phase, progressing to acute myeloid leukemia (AML). …”
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Effect on the size of optic nerve sheath diameter in patients undergoing surgeries under spinal anaesthesia versus peripheral nerve blocks – A randomised controlled study by Sangineni Kalyani Surya Dhana Lakshmi, A Bhargav Ram, CH Rama Krishna Prasad, Sandeep Garre, Anish Waghray

“…Background and Aims: Post-dural puncture headache is a complication of spinal anaesthesia, theorised to be triggered by a lowering in intracranial pressure due to the cerebrospinal fluid leak through the dural puncture. Our objective was to evaluate whether there is a decrease in optic nerve sheath diameter (ONSD) with a reduction in intracranial pressure after spinal anaesthesia. …”
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Rheological monitoring of tau protein polymerisation with acoustic waves sensor by P. Didier, F. Razan, E. Caplain, M. Michiel, C. Delamarche, C. Nogues, J.Y. Le Huerou, S. Serfaty, P. Larzabal

“…The tau protein is present in complex products such as blood and cerebrospinal fluid. The experimental results show that the acoustic wave system allows to differentiate between tau protein solutions with different states of polymerisation.…”
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Machine learning-assisted cancer diagnosis in patients with paraneoplastic autoantibodies by Alireza Maleki, Mohammad Mahdi Mirza Ali Mohammadi, Shahab Gholizadeh, Behnaz Dalvandi, Mohammad Rahimi, Aidin Tarokhian

“…Laboratory data comprised serum or cerebrospinal fluid (CSF) paraneoplastic autoantibody panels. …”
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Clinical and laboratory profile and its outcome in scrub typhus-positive acute febrile illness cases in the Pediatric Department of BRD Medical College, Gorakhpur by Anamika Chaudhary, Bhoopendra Sharma, Ashok Kumar Pandey, Priyanka Singh

“…Patients underwent the required investigations, such as cerebrospinal fluid examination. Results: Seventy-two (37.1%) of the 194 AFI patients were scrub typhus positive. …”
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Diplopia, Convergent Strabismus, and Eye Abduction Palsy in a 12-Year-Old Boy with Autoimmune Thyroiditis by Pedro Marques, Sandra Jacinto, Maria do Carmo Pinto, Catarina Limbert, Lurdes Lopes

“…Pseudotumor cerebri (PTC) is defined by clinical criteria of increased intracranial pressure, elevated intracranial pressure with normal cerebrospinal fluid (CSF) composition, and exclusion of other causes such tumors, vascular abnormalities, or infections. …”
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Case report: From misdiagnosis to timely detection: a clinical and imaging guide to neurological presentations of diffuse large B-cell lymphoma—insights from six cases by Chunxiao Yang, Zihua Gong, Tao Wang, Huijuan Yuan, Weinan Na, Wei Xie, Shengyuan Yu

“…These cases underscore the imperative for neurologists to maintain a high index of suspicion for lymphoma in atypical presentations and to judiciously integrate multimodal diagnostic modalities—such as comprehensive imaging, cerebrospinal fluid analysis, and biopsy—to expedite diagnosis and initiate timely intervention.…”
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Ofatumumab successfully treats myelin oligodendrocyte glycoprotein antibody-associated disease accompanied by Epstein-Barr viral infection: a case series by Chen Min, Bi Zhuajin, Liu Peidong, Li Ruoyu, Liu Ju, Liu Hongbo

“…Both presented inflammation response in the cerebrospinal fluid (CSF), demonstrating elevated level of cell accounts and protein. …”
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Changes to Intermediary Metabolites in Sporadic and LRRK2 Parkinson’s Disease Demonstrated by Proton Magnetic Resonance Spectroscopy by Jan O. Aasly, Oddbjørn Sæther, Krisztina K. Johansen, Tone F. Bathen, Guro F. Giskeødegård, Linda R. White

“…To study the levels of intermediary metabolites in cerebrospinal fluid (CSF) from patients with PD, either of sporadic type or in carriers of the LRRK2 p.G2019S mutation. …”
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Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα by Massimo Tortarolo, Daniele Lo Coco, Pietro Veglianese, Antonio Vallarola, Maria Teresa Giordana, Gabriella Marcon, Ettore Beghi, Marco Poloni, Michael J. Strong, Anand M. Iyer, Eleonora Aronica, Caterina Bendotti

“…Changes in TNFα levels are reported in blood, cerebrospinal fluid, and nerve tissues of ALS patients and animal models. …”
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ANTITUMOR EFFECT OF ELECTROMAGNETIC FIELDS AND THEIR EFFECT ON PAIN IN EXPERIMENTAL AND CLINICAL ONCOLOGY by E. M. Frantsiyants, E. A. Sheiko

“…The therapeutic anti-pain effect is associated with the stimulation of the antinociceptive system, an increase in the synthesis of natural analgesics — endorphins with their subsequent release into the cerebrospinal fluid and blood. As it has already been shown, with the increase in the intensity of pain and its duration, all indicators of the quality of life and the results of treatment of the patient deteriorate, so the search for ways to improve the antitumor effectiveness of specialized treatment and eliminate the causes that prevent their im­plementation continue to be relevant and in demand.…”
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Progressive histological and behavioral deterioration of a novel mouse model of secondary hydrocephalus after subarachnoid hemorrhage by Xuehai Deng, Jianlin Ding, Chang Liu, Zhong Wang, Junchi Wang, Qiyue Duan, Weida Li, Xinlong Chen, Xiaoping Tang, Long Zhao

“…Choroid plexus cerebrospinal fluid (CSF) hypersecretion, obliterative arachnoiditis occluding the arachnoid villi, lymphatic obstruction, subarachnoid fibrosis, and glymphatic system injury are considered the main pathological mechanisms of hydrocephalus after SAH. …”
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High resolution multi-delay arterial spin labeling with self-supervised deep learning denoising for pediatric choroid plexus perfusion MRI by Qinyang Shou, Chenyang Zhao, Xingfeng Shao, Megan M Herting, Danny JJ Wang

“…Choroid plexus (CP) is an important brain structure that produces cerebrospinal fluid (CSF). CP perfusion has been studied using multi-delay arterial spin labeling (MD-ASL) in adults but not in pediatric populations due to the challenge of small CP size in children. …”
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The Potential Role of Matrix Metalloproteinases 8 and 9 and Myeloperoxidase in Predicting Outcomes of Bacterial Meningitis of Childhood by Okko Savonius, Irmeli Roine, Saeed Alassiri, Taina Tervahartiala, Otto Helve, Josefina Fernández, Heikki Peltola, Timo Sorsa, Tuula Pelkonen

“…Matrix metalloproteinases (MMPs) and myeloperoxidase (MPO) contribute to the inflammatory cascade in the cerebrospinal fluid (CSF) during bacterial meningitis. We determined levels of MPO, MMP-8, MMP-9, and tissue inhibitor of metalloproteinase- (TIMP-) 1 in the CSF of children with bacterial meningitis and investigated how these inflammatory mediators relate to each other and to the disease outcomes. …”
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Short-Course Induction Treatment with Intrathecal Amphotericin B Lipid Emulsion for HIV Infected Patients with Cryptococcal Meningitis by Gerardo Alvarez-Uria, Manoranjan Midde, Raghavakalyan Pakam, Pradeep Sukumar Yalla, Praveen Kumar Naik, Raghuprakash Reddy

“…After adjustment for baseline characteristics (gender, age, altered mental status or seizures at presentation, CD4 cell count, white blood cells, cerebrospinal fluid white cells, and haemoglobin), the use of Regimen II was associated with a significant relative risk reduction in mortality (adjusted hazard ratio 0.4, 95% confidence interval, 0.22–0.76) and 26.7% absolute risk reduction (95% confidence interval, 9.9–43.5) at 12 weeks. …”
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Short-Term Outcomes of Posterior Fossa Decompression with or without Duraplasty for Chiari Malformation Type 1: Insights from a Tertiary Care Hospital by Muhammad Idris Khan, Adnan Munir, Sajjad Ullah, Sikandar Ali Khan

“…Results: 52 patients were included in our study out of which 28 underwent posterior fossa decompression with duraplasty and 24 without duraplasty. 8 patients (15.4%) experienced postoperative complications. Cerebrospinal fluid leaks were observed in 3 cases (5.8%), all of which occurred in the PFD with duraplasty group. …”
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A fulminant case of JC virus encephalopathy supporting a novel syndrome associated with JC virus infection of cortical neurons by Matteo Ciocca, Marta Pirovano, Monica Lodi, Antonino Romeo, Vincenza Fetoni

“…Serological tests and cerebrospinal fluid analysis were all negative for infectious diseases. …”
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Case Report: First use of dental bisphenol A-glycidyl methacrylate composite without UV light polymerization for repair of iatrogenic CSF leak following a frontal craniotomy plus t... by Haman Nassourou Oumarou, Haman Nassourou Oumarou, Ndome Toto Orlane

“…ObjectiveThis study aimed to evaluate the efficacy and safety of bisphenol A-glycidyl methacrylate (bis-GMA) without UV light polymerization for the repair of refractory iatrogenic cerebrospinal fluid (CSF) leaks with large skull base defects.BackgroundCSF leakage remains a common complication after neurosurgical interventions with a substantial resultant impact on morbidity and increased healthcare costs. …”
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Severe CSF immune cell alterations in cryptococcal meningitis gradually resolve during antifungal therapy by Christine Dambietz, Michael Heming, Tobias J. Brix, Andreas Schulte-Mecklenbeck, Phil-Robin Tepasse, Catharina C. Gross, Jonel Trebicka, Heinz Wiendl, Gerd Meyer zu Hörste

“…Host response and immunological alterations in the cerebrospinal fluid (CSF) after invasion of Cryptococcus neoformans to the central nervous system have been investigated before but rigorous and comprehensive studies examining cellular changes in the CSF of patients with cryptococccal meningitis are still rare. …”
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Seizure aggravation by ampicillin/sulbactam in an elderly patient with status epilepticus by Kaoru Obata, Masako Kinoshita, Akiyo Shinde, Toshihiko Suenaga

“…He had been suffering from severe ulcerative colitis and infectious enteritis, delirium, atrial fibrillation and deep venous thrombosis. His cerebrospinal fluid analysis was unremarkable. Four days after starting levetiracetam, he had a cluster of seizures with impaired consciousness, consistent with status epilepticus. …”
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