Identifying potential drug targets for myocardial infarction through Mendelian randomization. by Xiangyou Yu, Shasha Liu

“…<h4>Background</h4>This study explored the associations between plasma and cerebrospinal fluid (CSF) proteins and myocardial infarction (MI) risk. …”
Get full text

Surgery impairs glymphatic activity and cognitive function in aged mice by Kai Chen, Xingyu Du, Melissa A. Chao, Zhongcong Xie, Guang Yang

“…The glymphatic system, a brain-wide network of perivascular pathways, facilitates cerebrospinal fluid (CSF) flow and supports the clearance of metabolic waste. …”
Get full text

Infection-Induced Elevated Plasma Perampanel in a Patient with Hemimegalencephaly by Yuya Kinoshita, Hiroe Ueno, Hirofumi Kurata, Chizuru Ikeda, Erika Hori, Takumi Okada, Tomoyuki Shimazu, Isao Fujii, Makoto Matsukura, Hoseki Imamura

“…Further examinations (blood, cerebrospinal fluid, brain magnetic resonance images, and electroencephalogram) revealed no physical cause for impaired consciousness. …”
Get full text

Elizabethkingia anophelis: An uncommon cause of hospital-acquired septic meningitis and a rare cause of community-acquired meningitis in children: A case series by Sarjana Shuchi, Shweta Satija, Manoj B Jais

“…The organism was isolated from the cerebrospinal fluid of both the patients and the blood of only the neonate. …”
Get full text

A Case of Undetected Neuroborreliosis in a 75-Year-Old Chinese Male by Jenny Lamichhane, Rohail Haider, Michael Bekkerman, Sean Tilford, Shireen Hijaz, Bikash Bhattarai, Rajanish Bobde

“…It was only late in the course of his treatment that blood titers and cerebrospinal fluid analysis were positive for Lyme IgG and IgM. …”
Get full text

Acute Enterovirus Encephalitis as a Cause for Isolated Visual and Auditory Hallucinations in a 22-Year-Old Patient by M. Deest, C. Eberlein, S. Bleich, H. Frieling, T. Skripuletz, A. Neyazi

“…Here, we report the case of a 22-year-old woman with first time visual and auditory hallucinations due to an acute enterovirus encephalitis with no cerebrospinal fluid abnormalities but a positive PCR result for enterovirus (ECHO). …”
Get full text

Spontaneous Cervical Intradural Disc Herniation Associated with Ossification of Posterior Longitudinal Ligament by Dachuan Wang, Haifeng Wang, Wun-Jer Shen

“…The mass was surrounded by cerebrospinal fluid signal intensity margin, and caudally the ventral dura line appears divided into two, consistent with the “Y-sign” described by Sasaji et al. …”
Get full text

Perspectives in Molecular Imaging Using Staging Biomarkers and Immunotherapies in Alzheimer’s Disease by Benoît Leclerc, Abedelnasser Abulrob

“…The most promising diagnostic strategies in today’s world would consist in performing high diagnostic accuracy of combined modality imaging technologies using beta-amyloid 42 peptide-cerebrospinal fluid (CSF) positron emission tomography (PET), Pittsburgh compound B-PET, fluorodeoxyglucose-PET, total and phosphorylated tau-CSF, and volumetric magnetic resonance imaging hippocampus biomarkers for criteria evaluation and validation. …”
Get full text

Rituximab for Autoimmune Encephalitis with Epilepsy by Mohankumar Kurukumbi, Rahul H. Dave, Jose Castillo, Tulsi Shah, Joanne Lau

“…Diagnosis requires a syndrome consistent with an antibody identified in serum or cerebrospinal fluid (CSF) using methods that minimize risk of false-positives. …”
Get full text

Abdominal pseudocyst: a rare complication of ventriculoperitoneal shunt by Omar Al-Mahrouqi, Tariq Al-Saadi

“…The APC inhibits cerebrospinal fluid (CSF) absorption and causes shunt malfunction. …”
Get full text

Cervical Spine Ischemic Stroke Complicated by Spastic Quadriparesis and Ogilvie Syndrome: A Case Report and Literature Review by Salman Assad, Justin Nolte, Dharampreet Singh, Samrina Hanif, Paul Ferguson

“…The MRI brain, cerebrospinal fluid analysis, and rheumatologic evaluation were unremarkable. …”
Get full text

Diagnosis of acquired immunodeficiency virus from a Cryptococcus meningoencephalitis. Case Presentation by María Odeymi Urdanivia Cruz, Idalmis D. Reyes Rod´ríguez, Jorge E. Barletta del Castillo

“…He was admitted and microbiological studies of cerebrospinal fluid with Chinese ink staining that showed capsulated levaduriform cells, sign of Cryptococcus meningoencephalitis.…”
Get full text

Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis by Simone A. van den Berge, Josta T. Kevenaar, Jacqueline A. Sluijs, Elly M. Hol

“…Thus, we determined whether cortical astrogliosis occurs in PD, whether it is related to dementia, and whether this is reflected by the presence of glial fibrillary acidic protein (GFAP) and vimentin in cerebrospinal fluid (CSF). We have examined these proteins by immunohistochemistry in the frontal cortex and by Western blot in CSF of cases with PD, PD with dementia (PDD), dementia with Lewy bodies (DLB) and nondemented controls. …”
Get full text

Tropheryma whipplei infection presenting as indolent endophthalmitis by Rami Waked, Jeffrey K. Moore, Brandon Winward, Sophia Ham, Howard W. Hoyt, Leyla Azis

“…Gastrointestinal endoscopic and cerebrospinal fluid studies revealed no pathological or molecular evidence of the disease, complicating the diagnosis. …”
Get full text

Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis by H. Cromlin, H. Rodriguez-Villalobos, A. Deplano, T. Duprez, P. Hantson

“…The culture of blood, cerebrospinal fluid, and urine grew positive for a multisensitive E. coli. …”
Get full text

Human Herpesvirus 6 is Associated with Status Epilepticus and Hyponatremia after Umbilical Cord Blood Transplantation by Fernanda Leite de Souza Franceschi, Jaime Green, Zuzan Cayci, Evan Mariash, Mustapha Ezzeddine, Veronika Bachanova, Celalettin Ustun

“…The authors report a case involving a 65-year-old man with nonconvulsive status epilepticus 34 days after umbilical cord blood transplantion for chronic lymphocytic leukemia. Cerebrospinal fluid and serum were positive for human herpesvirus 6 (HHV6). …”
Get full text

Pantoea agglomerans Infections in Children: Report of Two Cases by Shraddha Siwakoti, Rinku Sah, Rupa Singh Rajbhandari, Basudha Khanal

“…Postoperative meningitis was confirmed as cerebrospinal fluid culture revealed P. agglomerans. She responded well with a 14-day intravenous (IV) course of ceftriaxone. …”
Get full text

Brain injury biomarkers and applications in neurological diseases by Han Zhang, Jing Wang, Yang Qu, Yi Yang, Zhen-Ni Guo, Yanjie Yin

“…Different biomarkers in the blood or the cerebrospinal fluid are associated with specific physiological and pathological processes. …”
Get full text

All-Trans Retinoic Acid-Induced Pseudotumor Cerebri during Induction Therapy for Acute Promyelocytic Leukemia: A Case Report and Literature Review by Dylan Holmes, Prakash Vishnu, Russell K. Dorer, David M. Aboulafia

“…PC is a rare disorder characterized by neurologic and ocular signs and symptoms of increased intracranial pressure, but with normal cerebrospinal fluid composition and normal brain imaging. …”
Get full text

Tumour Necrosis Factor-α Production and Immune Cell Activation in Tuberculous Meningitis by C. M. Mastroianni, F. Paoletti, C. Valenti, A. P. Massetti, V. Vullo, S. Delia

“…The local production of tumour necrosis factor-α (TNFα) was evaluated in the cerebrospinal fluid (CSF) from ten patients with tuberculous meningitis (TBM). …”
Get full text