Bioreactance-Based Noninvasive Fluid Responsiveness and Cardiac Output Monitoring: A Pilot Study in Patients with Aneurysmal Subarachnoid Hemorrhage and Literature Review by Sanjeev Sivakumar, Christos Lazaridis

“…For the prevention and treatment of delayed cerebral ischemia (DCI), euvolemia is advocated and caution is made towards the avoidance of hypervolemia. …”
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Erythropoietin, Forkhead Proteins, and Oxidative Injury: Biomarkers and Biology by Kenneth Maiese, Jinling Hou, Zhao Zhong Chong, Yan Chen Shang

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Mitoxantrone Therapy for Acute Posterior Multifocal Placoid Pigment Epitheliopathy with Cerebral Vasculitis by Hélène Massé, Jean-Laurent Guyomard, Dominique Baudet, Jean-François Pinel, Gilles Edan, Jean-François Charlin

“…A relapse of APMPPE was diagnosed, complicated with lymphocytic meningitis and cerebral ischemia. Intravenous therapy with mitoxantrone was performed in combination with methylprednisolone. …”
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Complement Inhibition as a Proposed Neuroprotective Strategy following Cardiac Arrest by Brad E. Zacharia, Zachary L. Hickman, Bartosz T. Grobelny, Peter A. DeRosa, Andrew F. Ducruet, E. Sander Connolly

“…A dearth of effective treatment strategies exists for global cerebral ischemia-reperfusion (GCI/R) injury following successful resuscitation from OHCA. …”
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Dental Mesenchymal Stem/Stromal Cells and Their Exosomes by Peter Stanko, Ursula Altanerova, Jana Jakubechova, Vanda Repiska, Cestmir Altaner

“…The therapeutic applicability of these cells and exosomes in dental practice, neurodegenerative diseases, and many other difficultly treatable diseases, like myocardial infarction, focal cerebral ischemia, acute lung or brain injury, acute respiratory distress syndrome, acute inflammation, and several others is concisely covered. …”
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Literature review of spontaneous subarachnoid haemorrhage: risk factors, diagnostic features, and complications (Part I) by J. Grigaitė, G. Rutkauskaitė, L. Piliponis, J. Ščerbak, D. Jatužis, J. Valaikienė

“…Mortality is significantly increased by common local and systemic complications: recurrent bleeding, hydrocephalus, acute convulsions, cardiovascular complications, and cerebral ischemia, the most common cause of which is vasospasm. …”
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Interleukin-16 Polymorphism Is Associated with an Increased Risk of Ischemic Stroke by Xiao-li Liu, Jian-zong Du, Yu-miao Zhou, Qin-fen Shu, Ya-guo Li

“…Interleukin-16 (IL-16) is identified as a proinflammatory cytokine that is a key element in the ischemic cascade after cerebral ischemia. We aimed to examine the relationship between the IL-16 polymorphisms and the risk of ischemic stroke in a Chinese population. …”
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The Effects of Exercise on Cognitive Recovery after Acquired Brain Injury in Animal Models: A Systematic Review by Elise Wogensen, Hana Malá, Jesper Mogensen

“…Search strings used were: exercise (and) animal model (or) rodent (or) rat (and) traumatic brain injury (or) cerebral ischemia (or) brain irradiation. Studies were selected if they were (1) in English, (2) used adult animals subjected to acquired brain injury, (3) used exercise as an intervention tool after inflicted injury, (4) used exercise paradigms demanding movement of all extremities, (5) had exercise intervention effects that could be distinguished from other potential intervention effects, and (6) contained at least one measure of cognitive and/or emotional function. …”
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Literature review of spontaneous subarachnoid haemorrhage: treatment management and prevention (Part II) by J. Grigaitė, G. Rutkauskaitė, L. Piliponis, J. Ščerbak, D. Jatužis, J. Valaikienė

“…For the prevention of late cerebral ischemia, it is recommended to administer calcium channel blocker nimodipine and to maintain euvolemia. …”
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A scoping review protocol on brain PaCO2 levels at altitude. by Hanna Tang, Laurel Charlesworth, Manoj Lalu, Brian Dewar, Risa Shorr, Dariush Dowlatshahi

“…This would be the steppingstone for more in-depth analyses into the cerebral autoregulatory consequences of high altitude on cerebral ischemia to form future guidelines.<h4>Methods and analysis</h4>We will follow scoping review methods recommended by the Joanna Briggs Institute. …”
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Neurological damages in COVID‐19 patients: Mechanisms and preventive interventions by Sibani Sarkar, Subhajit Karmakar, Malini Basu, Pratyasha Ghosh, Mrinal K Ghosh

“…It is associated with systemic inflammation, myocardial infarction, neurological illness including ischemic strokes (e.g., cardiac and cerebral ischemia), and even death through multi‐organ failure. …”
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Uncommon Occurrences of Air Embolism: Description of Cases and Review of the Literature by Giorgio Berlot, Adriano Rinaldi, Marco Moscheni, Massimo Ferluga, Perla Rossini

“…Whereas in the first patient the gas embolism was associated with only relatively mild digestive symptoms, in the remaining two it caused a massive cerebral ischemia and an extended myocardial infarction, respectively. …”
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A vascular endothelial growth factor–loaded chitosan-hyaluronic acid hydrogel scaffold enhances the therapeutic effect of adipose-derived stem cells in the context of stroke by Zhijian Zheng, Xiaohui Lin, Zijun Zhao, Qiang Lin, Ji Liu, Manli Chen, Wenwen Wu, Zhiyun Wu, Nan Liu, Hongbin Chen

“…Subsequently, we developed a chitosan-hyaluronic acid hydrogel scaffold that incorporated vascular endothelial growth factor and first injected the scaffold into an animal model of cerebral ischemia-reperfusion injury. When loaded with adipose-derived stem cells, this vascular endothelial growth factor–loaded scaffold markedly reduced neuronal apoptosis caused by oxygen-glucose deprivation/reoxygenation and substantially restored mitochondrial membrane potential and axon morphology. …”
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MicroRNA-29b Suppresses Inflammation and Protects Blood-Brain Barrier Integrity in Ischemic Stroke by Xiaoqing Ma, Ho Jun Yun, Kenneth Elkin, Yunliang Guo, Yuchuan Ding, Guangwen Li

“…Objectives. Following cerebral ischemia, microRNA- (miR-) 29b in circulating blood is downregulated. …”
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A realistic human head phantom for electromagnetic detection of brain diseases by Zelin Bai, Diyou Chen, Ke Ma, Gui Jin, Jinlong Qiu, Quanquan Li, Haocheng Li, Mingsheng Chen

“…This article combines high-precision computed tomography (CT) images and magnetic resonance imaging (MRI) images to establish an electromagnetic numerical model of the human head with a real anatomical structure. (1) It had Asian characteristics and encompassed 14 different structures, including skin, muscles, cranial bones, cerebrospinal fluid, cerebral veins, cerebral arteries, gray matter, white matter of the brain, basal ganglia, thalamus, cerebellum, brainstem, eyeballs, and vertebrae. (2) The model used a combination of 0.625 mm-resolution CT and 1 mm-resolution MRI image data for reconstruction, with a smooth surface and high accuracy. (3) Within the simulation environment, this model enabled the generation of various brain disease scenarios, such as different types and degrees of cerebral hemorrhage and cerebral ischemia. It proved valuable for studying the distribution of electromagnetic fields in the human head and for investigating novel electromagnetic detection techniques exploiting brain tissue dielectric properties. (4) The created physical model and the numerical model were derived from the same person, which provided a good continuity between simulation experiments and physical experiments, and provided a realistic verification platform for the research of electromagnetic detection technology for brain diseases, such as differentiating the kind of stroke, monitoring brain edema, brain tumor microwave imaging, and diagnosis of Alzheimer’s disease.…”
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A comprehensive review on alpha-lipoic acid delivery by nanoparticles by Navid Mosallaei, Amirhossein Malaekeh-Nikouei, Setayesh Sarraf Shirazi, Javad Behmadi, Bizhan Malaekeh-Nikouei

“…ALA encapsulated in niosomes showed potential for treating cerebral ischemia, a condition largely linked to stroke. …”
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Isosteviol Sodium Promotes Neurological Function Recovery in a Model of Spinal Cord Injury in Rats by Tongxia Zhang, Tao Zhang, Han Yu, Lingyi Chi

“…In previous studies, Isosteviol sodium (STVNa) has been shown to protect rats against acute focal cerebral ischemia; however, the effects of STVNa on SCI recovery in rats remain unknown. …”
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Construction of an lncRNA-mediated ceRNA network to investigate the inflammatory regulatory mechanisms of ischemic stroke. by Meimei Xu, Shan Yuan, Xing Luo, Mengsi Xu, Guangze Hu, Zhe He, Xinyuan Yang, Rui Gao

“…In this study, we established a cerebral ischemia-reperfusion injury model using middle cerebral artery occlusion (MCAO) in male Sprague-Dawley rats. …”
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Dose Effect Evaluation and Therapeutic Window of the Neuro-EPO Nasal Application for the Treatment of the Focal Ischemia Model in the Mongolian Gerbil by Iliana Sosa Teste, Yuneidys Mengana Tamos, Yamila Rodríguez Cruz, Adriana Muñoz Cernada, Janette Cruz Rodríguez, Nelvis Subirós Martínez, Rosa Maria Coro Antich, Alina González-Quevedo, Julio Cesar García Rodríguez

“…The aim of this study was to determine the Neuro-EPO delivery into the central nervous system (CNS) to exert a neuroprotective effect in cerebral ischemia model of the Mongolian gerbil. The Neuro-EPO in a rate of 249.4 UI every 8 hours for 4 days showed 25% higher viability efficacy (𝑃>0.01), improving neurological score and behavior of the spontaneous exploratory activity, the preservation of CA3 areas of the hippocampus, the cortex, and thalamic nuclei in the focal ischemia model of the Mongolian gerbil. …”
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PET Quantification of Cerebral Oxygen Metabolism in Small Animals by Takashi Temma, Kazuhiro Koshino, Tetsuaki Moriguchi, Jun-ichiro Enmi, Hidehiro Iida

“…Since small animals such as rats are widely used to study various diseases including cerebral ischemia, cerebrovascular diseases, and neurodegenerative diseases, the development of a noninvasive in vivo measurement method of cerebral oxygen metabolic parameters such as oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) as well as cerebral blood flow (CBF) and cerebral blood volume (CBV) has been a priority. …”
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