Retracted: Block Copolymer Nanomicelle-Encapsulated Curcumin Attenuates Cerebral Ischemia Injury and Affects Stem Cell Marker Expression by Inhibiting lncRNA GAS5 by Stem Cells International

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Metabolomic and transcriptomic analyses revealed potential mechanisms of Anchusa italica Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/β-catenin pathway modulation by Wenta Tan, Shuo Fu, Yufei Wang, Bojun Hu, Guiquan Ding, Li Zhang, Wen Zhang, Guanhua Du, Junke Song

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Electroacupuncture Pretreatment Elicits Tolerance to Cerebral Ischemia/Reperfusion through Inhibition of the GluN2B/m-Calpain/p38 MAPK Proapoptotic Pathway by Bao-yu Zhang, Guan-ran Wang, Wen-hua Ning, Jian Liu, Sha Yang, Yan Shen, Yang Wang, Meng-xiong Zhao, Li Li

“…As one of the first steps in the pathology of cerebral ischemia, glutamate-induced excitotoxicity progresses too fast to be the target of postischemic intervention. …”
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Effects and mechanisms of long-acting glucagon-like peptide-1 receptor agonist semaglutide on microglia phenotypic transformation and neuroinflammation after cerebral ischemia/reperfusion in rats by Rulin Mi, Huifeng Cheng, Rui Chen, Bo Bai, An Li, Fankai Gao, Guofang Xue

Subjects: “…cerebral ischemia-reperfusion…”
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Neurobiological Mechanisms Underlying Psychological Dysfunction After Brain Injuries by Prashin Unadkat, Tania Rebeiz, Erum Ajmal, Vincent De Souza, Angela Xia, Julia Jinu, Keren Powell, Chunyan Li

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Electroacupuncture inhibits neuronal pyroptosis in ischemic brain injury through modulating SIRT5-mediated NEK7 succinylation by Lili Ma, Meiling Zhang, Ting Chen, Limin Wang, Qilong Deng

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The E3 ubiquitin ligase MARCH1 mediates downregulation of plasma membrane GABAB receptors under ischemic conditions by inhibiting fast receptor recycling by Musadiq A. Bhat, Mohammad Hleihil, Irene Mondéjar, Thomas Grampp, Dietmar Benke

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Protective Mechanism of Alisol A 24-Acetate on Brain Microvascular Endothelial Cells in Mice with Cerebral Ischemia-Reperfusion Injury by TRPM2/Akt/GSK3β Pathway by LI Huihong, DENG Yunfei, WEI Wei, ZHAN Zengtu, LIN Libin, XUE Xiehua

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Shaoyao-Gancao Decoction Promoted Microglia M2 Polarization via the IL-13-Mediated JAK2/STAT6 Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury by Juanjuan Lu, Jie Wang, Long Yu, Rong Cui, Ying Zhang, Hanqing Ding, Guofeng Yan

“…Microglia in the penumbra shifted from M2 to M1 phenotype between 3 and 5 days after cerebral ischemia-reperfusion, which promoted local inflammation and injury. …”
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Salvianolic Acid D Alleviates Cerebral Ischemia-Reperfusion Injury by Suppressing the Cytoplasmic Translocation and Release of HMGB1-Triggered NF-κB Activation to Inhibit Inflammatory Response by Wen Zhang, Junke Song, Wan Li, Dewen Kong, Yu Liang, Xiaoyue Zhao, Guanhua Du

“…This study is aimed at investigating the therapeutic effect and anti-inflammatory mechanism of salvianolic acid D (SalD) against cerebral ischemia/reperfusion (I/R) injury. A rat middle cerebral artery occlusion/reperfusion (MCAO/R) injury model was established, and an oxygen-glucose deprivation/reoxygenation (OGD/R) injury model was established in PC12 cells. …”
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Electroacupuncture at Quchi and Zusanli Enhances the Proliferation of Cortex and SVZ-derived Neural Stem Cell in Cerebral Ischemia-Reperfusion Injured Rats Via Activation of Notch1 Signaling Pathway by Jing TAO, Weilin LIU, Jia HUANG, Xiehua XUE, Shanli YANG, Yi ZHENG, Yunjiao LIN, Xiaoqian YE, Meiqin LIN, Lidian CHEN

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Interleukin-22 Plays a Protective Role by Regulating the JAK2-STAT3 Pathway to Improve Inflammation, Oxidative Stress, and Neuronal Apoptosis following Cerebral Ischemia-Reperfusion Injury by Yongfei Dong, Chengyun Hu, Chunxia Huang, Jie Gao, Wanxiang Niu, Di Wang, Yang Wang, Chaoshi Niu

“…The interleukins (ILs) are a pluripotent cytokine family that have been reported to regulate ischemic stroke and cerebral ischemia/reperfusion (I/R) injury. IL-22 is a member of the IL-10 superfamily and plays important roles in tissue injury and repair. …”
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The mitochondria as a potential therapeutic target in cerebral I/R injury by Susu Fang, Susu Fang, Wenzhou Huang, Wenzhou Huang, Xinhui Qu, Xinhui Qu, Wen Chai

Subjects: “…cerebral ischemia/reperfusion injury (CIRI)…”
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Fyn Signaling in Ischemia-Reperfusion Injury: Potential and Therapeutic Implications by Fang Du, Tao Tang, Qingzhu Li, Jiaxin Liu

“…This paper reviews the role of Fyn in the pathological process of cerebral ischemia-reperfusion, including neuroexcitotoxicity and neuroinflammation, to explore how Fyn affects specific signal cascades and leads to cerebral ischemia-reperfusion injury. …”
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Research Progress on the Mechanism of Acupuncture Treatment of Ischemic Stroke Based on the Space Construction of Nerve-vascular Unit by LI Mengxing, WNAG Yu, LI Zhen, LIU Fang, SHI Kejian

“…The selection of targeted interventions among many targets could provide a direction to elucidate the possible material basis and effective target of acupuncture to reduce cerebral ischemic injury.ConclusionThe mechanism of acupuncture treatment of cerebral ischemia is closely related to NVU, which plays a synergistic neuroprotective role by bidirectional regulation of NVU spatial architecture, and it is the key to promoting functional recovery after cerebral ischemia.…”
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Role of microRNAs in Stroke and Poststroke Depression by Han Yan, Min Fang, Xue-Yuan Liu

“…Herein, studies on the role of miRNAs in the cerebral ischemia and PSD were reviewed, and results may be helpful for the diagnosis and prognosis of cerebral ischemia and PSD with miRNAs in clinical practice.…”
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Neuroinflammation and Cerebrovascular Disease in Old Age: A Translational Medicine Perspective by Mario Di Napoli, Imtiaz M. Shah

“…However, the pathophysiological mechanisms of brain response to cerebral ischemia in old age are currently poorly understood. …”
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The effect of beet leaf (Beta vulgaris) extract on learning and memory after cerebral ischemic reperfusion in rats by Kobra Mirahmadi, Najmeh Asgharzadeh, Zahra Lorigooini, Marzieh Mardani, Zahra Rabiei, Diana Shahrani, Mohamad Shahrani, Mehrdad Shahrani Korrani

“…Background and aims: Cerebral ischemia causes tissue oxidative damage and leads to cell death. …”
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Comparative Effects of Glenzocimab and Eptifibatide on Bleeding Severity in 2 Mouse Models of Intracranial Hemorrhage by Sébastien Dupont, Héloïse Lebas, Sabrina Mavouna, Eloïse Pascal, Astride Perrot, Adrien Cogo, Marie‐Charlotte Bourrienne, Carine Farkh, Mialitiana Solo Nomenjanahary, Véronique Ollivier, Fatima Zemali, Bernhard Nieswandt, Stéphane Loyau, Martine Jandrot‐Perrus, Eric Camerer, Jean‐Philippe Desilles, Mikael Mazighi, Yacine Boulaftali, Benoît Ho‐Tin‐Noé

“…Background Antiplatelet drugs represent potential candidates for protecting the penumbral microcirculation during cerebral ischemia and improving the benefits of arterial recanalization in ischemic stroke. …”
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The E3-ligase Siah2 activates mitochondrial quality control in neurons to maintain energy metabolism during ischemic brain tolerance by Maria Josè Sisalli, Elena D’Apolito, Ornella Cuomo, Giovanna Lombardi, Michele Tufano, Lucio Annunziato, Antonella Scorziello

“…The balance between mitophagy and biogenesis is needed to reduce cerebral ischemia-induced cell death. Ischemic preconditioning (IPC) represents an adaptation mechanism of CNS that increases tolerance to lethal cerebral ischemia. …”
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