Drug-Induced Myoclonus: A Systematic Review by Jamir Pitton Rissardo, Ana Letícia Fornari Caprara, Nidhi Bhal, Rishikulya Repudi, Lea Zlatin, Ian M. Walker

“…The subclasses of medications with level A evidence were intravenous anesthetics (etomidate), cephalosporins (ceftazidime, cefepime), fluoroquinolones (ciprofloxacin), selective serotonin reuptake inhibitors (citalopram, escitalopram, paroxetine, sertraline), tricyclic antidepressant (amitriptyline), glutamate antagonist (amantadine), atypical antipsychotics (clozapine, quetiapine), antiseizure medications (carbamazepine, oxcarbazepine, phenytoin, gabapentin, pregabalin, valproate), pure opioid agonist (fentanyl, morphine), bismuth salts, and mood stabilizers (lithium). …”
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Predominance of OXA-48 Carbapenemase-Producing Enterobacterales in a Moroccan Hospital by El Mehdi Belouad, Elmostafa Benaissa, Nadia El Mrimar, Fatna Bssaibis, Adil Maleb, Mostafa Elouennass

“…The Enterobacterales isolates resistant to third-generation cephalosporins (3GC) and/or carbapenems were subjected to the Carba NP test and an immunochromatographic test for phenotypic detection. …”
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The effect of the nisin-based pharmaceutical formulation used in the treatment plan for cows with subclinical mastitis on the milk microbiota by M. N. Isakova, Ya. Yu. Lysova

“…The study showed that a significant number of Staphylococcus aureus isolates (53.1%) were resistant to I generation cephalosporins; 52.6% of the isolated Streptococcus dysgalactiae strains showed resistance to tetracyclines; 33.3% of Staphylococcus haemolyticus isolates were resistant to macrolides. 42.1; 35.3 and 62.5% of Enterococcus faecium, Aerococcus viridans and coliform bacteria isolates, respectively, were resistant to penicillins. 38.5% of Staphylococcus epidermidis isolates were found to be resistant to tetracyclines. …”
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Microbiological Profile of Neonatal Sepsis at a Maternity Hospital in Omdurman, Sudan by Manal Abdelaziz, Yassir Hamadalnil, Omaima Hashim, Tahane Bashir, E. S. Mahjoub

“…Gram-negative organisms were sensitive to Imepenem (97.3%) and Meropenem (80.5%) and resistant to third-generation Cephalosporins (65.3%) and Amoxicillin/Clavulanic acid (91.4%). …”
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Characterization of Pathogenic Bacteria Isolated from Sudanese Banknotes and Determination of Their Resistance Profile by Noha Ahmed Abd Alfadil, Malik Suliman Mohamed, Manal M. Ali, El Amin Ibrahim El Nima

“…Our study has isolated bacteria that are resistant to penicillins and cephalosporins. Multidrug-resistant strains harboring resistant genes (mecA, blaCTX-M, and blaTEM) were also detected. …”
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Management of Recurrent Ventriculoperitoneal Shunt Infections in Adult Patients by Neval Elgormus, Yusuf Elgormus, Bagnu Dundar, Fatma Bozkurt, Huseyin Dogu, Hafize Uzun

“…The resistance rates were 85.2% for third-generation cephalosporins (3GCs), 83.3% for piperacillin–tazobactam, and 10.4% for carbapenem. …”
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Staphylococcal skin infection isolates from dogs without recent antibiotic exposure are 100% susceptible to clindamycin by W. Cooper Brookshire, Larry D. Ballard, Vernon C. Langston, Joo Youn Park, Keun-Seok Seo

“…If systemic antibiotics are indicated in these patients with this clinical history and presentation, clindamycin should be considered as first-line therapy, owing to its 100% susceptibility in this antibiogram and less selection pressure for antibiotic resistant bacteria, compared to alternatives such as cephalosporins.…”
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<i>Vibrio vulnificus</i>—A Review with a Special Focus on Sepsis by Marcello Candelli, Marta Sacco Fernandez, Cristina Triunfo, Andrea Piccioni, Veronica Ojetti, Francesco Franceschi, Giulia Pignataro

“…Treatment typically involves the use of doxycycline in combination with third-generation cephalosporins, although the emergence of multidrug-resistant strains is an escalating concern. …”
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Antimicrobial use regulations are associated with increased susceptibility among bovine Salmonella isolates from a U.S. surveillance system by Claudia Cobo-Angel, Maya Craig, Marwan Osman, Kevin J. Cummings, Casey L. Cazer

“…In the United States, two recent regulatory actions have changed the use of antimicrobials in livestock, banning production uses in 2017 and restricting extra-label use of cephalosporins in 2012. This study aimed to assess the impact of the 2012 and 2017 regulations on antimicrobial use in cattle in the United States by analyzing 18,627 bovine Salmonella AMR susceptibility patterns using data from the National Antimicrobial Resistance Monitoring System (NARMS). …”
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Correlation Analysis Between Multi-Drug Resistance Phenotype and Virulence Factor Expression of Clinical <i>Pseudomonas aeruginosa</i> by Wenli Xu, Runcheng Zhou, Jingwei Pan, Zhuangcong Liu, Xuyu Huang, Yueqiao Lin, Nan Li, Kecan Chen, Wenbo Sun, Yi Deng, Anping Yang, Xin Chen

“…PA, which were good at producing pyocyain and forming biofilm, were highly resistant to cephalosporins, beta-lactams and carbepenems; hence, such drugs are not proper for anti-infective treatment in clinics.…”
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Molecular Characterization and Epidemiology of Carbapenem-Resistant Enterobacteriaceae Isolated from Pediatric Patients in Guangzhou, Southern China by Fei Gao, Zhile Xiong, Bingshao Liang, Zhenting Huang, Qiulian Deng, Jielin Wang, Huamin Zhong, Yan Long, Sufei Zhu

“…All CRE isolates were highly resistant to the third- or fourth-generation cephalosporins, carbapenems, and β-lactam + β-lactamase inhibitors (94.4%–96.3%). …”
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Antipseudomonal β-Lactams Resistance in Iran by Mohammad Mahdi Rabiei, Keivan Asadi, Shervin Shokouhi, Mohammad Javad Nasiri, Ilad Alavi Darazam

“…The selection of empiric antipseudomonal antibiotics is absolutely uncertain and hazardous, and the risk of clinical failure may be more among cephalosporins and piperacillin-tazobactam as well as aztreonam. …”
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Genomic insights into a multidrug-resistant pandoraea apista clinical isolate carrying blaOXA-153 from China by Lirong Li, Yawen Zhang, Fang He, Ningjun wu

“…PA167 exhibited resistance to multiple antibiotics, including cephalosporins and carbapenems, and was susceptible only to sulfamethoxazole/trimethoprim. …”
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Antimicrobial Susceptibility of <i>Salmonella typhi</i> and <i>paratyphi</i> among Pediatric Population at Tertiary Care Center of North Delhi: A Retrospective Study by Shekhar Biswas, Sulagna Tripathy, Arvind Kumar, Sanjay Chattree

“…Third-generation cephalosporins as monotherapy are quite effective, and there is no need of adding azithromycin in combination form. …”
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Multidrug resistance of Pseudomonas aeruginosa: do virulence properties impact on resistance patterns? by Poulomi Saha, Rubaiya Binte Kabir, Chowdhury Rafiqul Ahsan, Mahmuda Yasmin

“…By using a binary logistic regression test with a 95% confidence interval, the relationship between MDR phenotypes and the virulence attributes was assessed.ResultsThe susceptibility rate among the isolates was 70–75% for aminoglycosides (amikacin, gentamicin, netilmicin), 15–20% for cephalosporins (ceftazidime, ceftriaxone), 30–35% for quinolones (ciprofloxacin, levofloxacin), 10–15% for tetracyclines (tigecycline, doxycycline), 15–20% for carbapenem (meropenem), 10–15% for sulfonamide (co-trimoxazole), 5–10% for amoxiclav, and 30–35% for piperacillin/tazobactam. …”
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Genomic characterization of Achromobacter genogroup 20 and identification of a potential species-specific marker by Mariana Papalia, Rocio Stucchi, Valeria Alexander, Liliana Clara, Mariángeles Visus, Gabriel Gutkind, Marcela Radice

“…Results: Isolate 413638 was identified as Achromobacter genogroup 20 ST365, showing resistance to third- and fourth-generation cephalosporins, aminoglycosides, and fluoroquinolones. …”
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Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers by Gaetano Zizzo, Gabriele Guazzardi, Daniela Bompane, Francesco Di Terlizzi, Giorgio Rotola, Ilario Stefani, Michela Medugno, Mario Bucalo, Antonino Mazzone

“…From 2016 to 2023, MDR+ sepsis frequency declined, due to decreased resistance to several antibiotic classes, such as cephalosporins, fluoroquinolones, and aminoglycosides; however, carbapenemase- and extended-spectrum beta-lactamase-producing Gram-negative bacteria, as well as vancomycin-resistant enterococci, increased, as did the frequency of polymicrobial sepsis following the COVID-19 outbreak.ConclusionThis work provides novel insights into sepsis management in internal medicine units, highlighting the need for validated biomarkers and implemented therapies in this scenario.…”
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Draft genome sequence of a co-harbouring blaNDM-5 and mcr-1.1 Escherichia coli phylogroup A isolate associated with patient colonisation in Ireland by Anna Tumeo, Francesca McDonagh, Aneta Kovarova, Kate Ryan, Christina Clarke, Georgios Miliotis

“…Resistance to beta-lactams, including carbapenems and cephalosporins was likely due to chromosomally identified blaNDM-5. …”
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Phenotypic Characterization and Antibiotic Resistance Patterns of Extended-Spectrum β-Lactamase- and AmpC β-Lactamase-Producing Gram-Negative Bacteria in a Referral Hospital, Saudi... by Mutasim E. Ibrahim, Mohammed Abbas, Abdullah M. Al-Shahrai, Bahaeldin K. Elamin

“…The resistance rates were significantly higher among ESBL producers than nonproducers for cephalosporins (p<0.001), amoxicillin/clavulanate (p<0.001), piperacillin/tazobactam (p=0.010), nitrofurantoin (p=0.027), aztreonam (p<0.001), ciprofloxacin (p=0.002), and trimethoprim/sulfamethoxazole (p<0.001). …”
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Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ... by Amy Robinson, Kamaljit Khalsa, Arjun Chandna, John Bowen, Viva Levee, Jan Coebergh, Tom Solomon, Clive Graham, David Turner, Robert Tilley, Tim Jones, Susan Hopkins, Matthew Stevens, Daniel White, Celestine Eshiwe, Anna Goodman, Ramandeep Singh, Robert S Heyderman, Nicholas Davies, Joseph Thompson, Ed Moran, Martin Williams, Rhea O’Regan, Simon Tiberi, Jonathan Lambourne, Naomi Bulteel, Susan Larkin, Ruth McEwen, Hassan Paraiso, Aarti Shah, Martin Wiselka, Sylviane Defres, Ernest Mutengesa, Maria Krutikov, Ruth Owen, David Griffith, David Harvey, Trupti Patel, Brendan Davies, Emma Mclean, Joanna Allen, Ali Khan, Alastair Miller, Ashutosh Deshpande, Christopher Green, Lewis Jones, Mark Melzer, Fiona McGill, Amanda Fife, Nimal Wickramasinghe, Stephanie Harris, Ewan Hunter, Jayne Ellis, Benedict Rogers, Imogen Fordham, Elen Vink, Victoria Ward, Anna Smith, Andrew Rosser, Alison Muir, Ken Woodhouse, John Shone, Iain Crossingham, Ryan Jayesinghe, Eavan Muldoon, Avneet Shahi, Terry John Evans, Jeremy Wong, Eloisa MacLachlan, Amy Chue, Karishma Gokani, Katherine Ajdukiewicz, Lucinda Barrett, Frances Edwards, Adam Usher, Mairi McLeod, Su su Htwe, Grace Duane, Nicholas Wong, Jennifer Poyner, Jenni Crane, Ollie Lloyd, Emma Chisholm, Ildiko Kustos, Sam Sutton, M. Estee Torok, Isobel Ramsay, Monica Ivan, Joshua York, Jennifer Ansett, Maithili Varadarajan, Priya Sekhon, James Cruise, Shivani Kanabar, Mirella Ling, Charlotte Milne, Jayanta Sarma, Aline Wilson, Lynn Urquhart, Sahar Eldirdiri, Leila White, Jody Aberdein, Phillip Simpson, Hnin Hay Mar, Keying Tan, Eint Shwe Zin thein, Mahmoud Aziz, Anthony Cadwgan, Natasha Weston, Salman Zeb, Angela Houston, Louise Wootton, Iona Willingham, Aimee Johnson, Ashley Horsley, Eamonn Trainor, Olivier Gaillemin, Nicholas J Norton, Katie Cheung, Megan Duxbury, Emilie Bellhouse, Helena Brezovjakova, Kanitkar Tanmay, Alexsander Dawidziuk, Razan Saman, Hugh Adler, Elshadai Ejere, Yiwen Soo, Wendy Beadles, Heather Sturgeon, Brodie Cameron, David Chadwick Ben Tomlinson, Claire McGoldrick, Katie McDowell, Mpho Molosiwa, Katherine FlackAdrian Kennedy, Phoebe Cross, Fay Perry, Vithusha Inpadhas, Sarathy Selvam, Vhairi Bateman, Henry Wu, Monika Pasztor, Ajanthiha Karunakaran, Basma Soliman, Andrew Blanshard, Harish Reddy, Helen Chesterfield, Ben Schroeder, Tee Keat Teoh, Sathyavani Subbarao, Caryn RosmarinLucy Bell, Emma McGuire, Robert Serafino, Ishaan Bhide, Karanjeet Sagoo, Indran Balakrishnan, Kajal Patel, Barzo Faris, Graeme Calver, Ricky Singh, Hazel Sanghvi, Mohamed Eltayeb, Rathur Haris

“…Median time to first dose of antibiotics was 3.2 hours (IQR 1.3–9.2). 80% received empirical parenteral cephalosporins. 55% ≥60 years and 31% of immunocompromised patients received anti-Listeria antibiotics. 21% received steroids. …”
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