Shigellosis Caused by CTX-M Type ESBL Producing Shigella flexneri in Two Siblings of Rural Nepal: First Case Report from the Country by Narayan Prasad Parajuli, Govardhan Joshi, Bashu Dev Pardhe, Jyotsna Shakya, Anjeela Bhetwal, Shreena Shakya, Roshan Pandit, Sumesh Shreekhanda Shrestha, Puspa Raj Khanal

“…In MDR strains, the third-generation cephalosporins have been used for the treatment, but, unfortunately, emerging reports of enzyme mediated β-lactam resistance among Shigella isolates from various parts of the world have greatly compromised the therapy of pediatric dysentery. …”
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Molecular modelling of betalactamic antibiotic by Elso Manuel Cruz Cruz, Grettel Díaz Ramón

“…<strong><br />Results</strong> There are variations in the calculated properties that make possible to define two groups of compounds: one for the monobactams and the inhibitors of the betalactamases, with less planarity in the ring and less reactivity and another one with the penicillins, cephalosporins and carbapenems, planer, more structurally stable and reactive. …”
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Urinary Catheter Colonization by Multidrug-Resistant Cedecea neteri in Patient with Benign Prostatic Hyperplasia by Peter S. Ginn, Serina B. Tart, Stephen M. Sharkady, Dorothea K. Thompson

“…This C. neteri isolate was resistant or intermediate to second-generation cephalosporins, penicillins, and certain β-lactamase inhibitor/β-lactam combinations. …”
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Ultrastructural Changes in Clinical and Microbiota Isolates of Klebsiella pneumoniae Carriers of Genes blaSHV, blaTEM, blaCTX-M, or blaKPC When Subject to β-Lactam Antibiotics by Dyana Leal Veras, Ana Catarina de Souza Lopes, Grasielle Vaz da Silva, Gabriel Gazzoni Araújo Gonçalves, Catarina Fernandes de Freitas, Fernanda Cristina Gomes de Lima, Maria Amélia Vieira Maciel, Ana Paula Sampaio Feitosa, Luiz Carlos Alves, Fábio André Brayner

“…Three K. pneumoniae clinical isolates were selected for the study with resistance profiles for third-generation cephalosporins, aztreonam, and/or imipenem and with different resistance genes for extended-spectrum β-lactamases (ESBL) or Klebsiella pneumoniae carbapenemase (KPC). …”
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A Multicenter Study of Beta-Lactamase Resistant Escherichia coli and Klebsiella pneumoniae Reveals High Level Chromosome Mediated Extended Spectrum β Lactamase Resistance in Ogun S... by Folasoge A. Adeyankinnu, Babatunde O. Motayo, Akinniyi Akinduti, John Akinbo, Joseph I. Ogiogwa, Bukola W. Aboderin, R. A. Agunlejika

“…There was above average susceptibility to the 2nd and 3rd generation cephalosporins. Plasmid profiles of tested isolates ranged from 9 kbp to 26 kbp with average of 14.99±2.3 kbp for E. coli and 20.98±1.8 kbp K. pneumoniae, 9.6% of ESBL positive E. coli plasmids were cured, while 3.9% of K. pneumoniae plasmids were cured after treatment. …”
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Biofilm Formation and Detection of Fluoroquinolone- and Carbapenem-Resistant Genes in Multidrug-Resistant Acinetobacter baumannii by María-Guadalupe Avila-Novoa, Oscar-Alberto Solís-Velázquez, Daniel-Eduardo Rangel-López, Jean-Pierre González-Gómez, Pedro-Javier Guerrero-Medina, Melesio Gutiérrez-Lomelí

“…Acinetobacter baumannii is an important opportunistic pathogen that shows resistance to cephalosporins, penicillins, carbapenems, fluoroquinolones, and aminoglycosides, the multiresistance being associated with its ability to form biofilms in clinical environments. …”
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Antibiotic Resistance of Salmonella enterica Serovar Typhi in Kolkata, India, and In Vitro Experiments on Effect of Combined Chemotherapy by Shyamapada Mandal, Manisha DebMandal, Nishith Kumar Pal

“…Thus, the treatment regimen was shifted to the third generation cephalosporins like ceftriaxone (Ct) and cefotaxime (Cf). …”
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Five-Year Retrospective Review of Acute Generalized Exanthematous Pustulosis by Chitprapassorn Thienvibul, Vasanop Vachiramon, Kumutnart Chanprapaph

“…Beta-lactams were the most common causal drug, particularly carbapenems and cephalosporins. This is the first report of Andrographis paniculata as an offending agent for AGEP. …”
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A Study on Clinical and Bacteriological Profile of Urinary Tract Infections (UTI) in North Karnataka by Chandrakala Guruprasad, Manjunath B M, Mohammed Abdul Quddus

“…Both organisms were sensitive to Cephalosporins followed by Carbapenem group of drugs.Conclusion Maintaining good blood sugar control and proper hygiene plays a significant role in controlling infection of urinary tract. …”
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Enhancement of antibacterial activity through phyto‐fabrication of silver nanoparticles with Ficus thonningii aqueous extracts by Dickens A. Ondigo, Were L. L. Munyendo, Dickson Andala, Apollo O. Maima, Josephat M. Mosweta, Kevin W. Odhiambo

“…Abstract The World Health Organisation reports higher levels of bacterial resistance to cephalosporins and carbapenems of above 54%. The sufficient redox capabilities of Ficus thonningii phytochemicals for Ag+ reduction to Ag0 and ultimately aggregation to nucleation are exploited for the first time in attempting to enhance the antibacterial activity. …”
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Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand by Rattiya Cheewapat, Jadsadaporn Redkimned, Sirikran Lekuthai, Thawatchai Kitti, Kannipa Tasanapak, Aunchalee Thanwisai, Sutthirat Sitthisak, Thanet Sornda, Hathaichanok Impheng, Sudarat Onsurathum, Udomluk Leungtongkam, Supaporn Lamlertthon, Siriwat Kucharoenphaibul, Jintana Wongwigkarn, Pantira Singkum, Pattrarat Chanchaithong, Rapee Thummeepak

“…Overall, we found the isolate to be resistant to seven antibiotic classes, penicillins, β-lactam/β-lactamase inhibitor combinations, cephalosporins, carbapenems, aminoglycosides, fluoroquinolones, and folate pathway antagonists. …”
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A Reliable Method for Identification of Antibiotics by Terahertz Spectroscopy and SVM by Jin Guo, Hu Deng, Quancheng Liu, Linyu Chen, Zhonggang Xiong, Liping Shang

“…THz time-domain spectroscopy (THz-TDS) was performed for sixteen types of antibiotics, including β-lactam, cephalosporins, macrolides, and tetracyclines. The absorption spectra within the frequency range of 0.2–1.5 THz were calculated. …”
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Persistent Bacteremia from Pseudomonas aeruginosa with In Vitro Resistance to the Novel Antibiotics Ceftolozane-Tazobactam and Ceftazidime-Avibactam by Louie Mar Gangcuangco, Patricia Clark, Cynthia Stewart, Goran Miljkovic, Zane K. Saul

“…Repeat blood cultures from Day 5 grew P. aeruginosa resistant to all cephalosporins, as well as to meropenem by Day 10. Susceptibility testing performed by measuring minimum inhibitory concentration by E-test (Biomerieux, Lenexa, KS) revealed that blood cultures from Day 10 were resistant to ceftazidime-avibactam and ceftolozane-tazobactam. …”
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Insight into the Burden of Antimicrobial Resistance among Bacterial Pathogens Isolated from Patients Admitted in ICUs of a Tertiary Care Hospital in India by Garima Gautam, Shweta Satija, Ravinder Kaur, Anil Kumar, Divakar Sharma, Megh Singh Dhakad

“…More than 80% of Acinetobacter species were found to be resistant to third-generation cephalosporins, aminoglycosides, and carbapenems, whereas minocycline (56.31% S) and colistin (100% S) were the most effective drugs. …”
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Frequency Of Bacterial Co-Infections Isolated from Covid-19 Positive Patients From Tertiary Care Hospital Of Karachi by Fouzia Zeeshan Khan, Ambreen Fatima, Hareem Gohar, Mehwish Sajjad, Mona Siddiqui, Saima Naseem

“…Klebsiella pneumonia exhibited high prevalence in sputum, with complete resistance observed in Cephalosporins and Co-trimoxazole. Conclusion: The study concludes a high frequency of superadded bacterial co-infections, caused most prominently by Acinetobacter baumannii, Klebsiella pneumonia, and Pseudomonas aeruginosa. …”
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Improving neonatal outcome by studying the incidence of maternal group B streptococcus colonization among pregnant women: A prospective observational study by Priyank Rajan, Mukesh Sanklecha, Saloni Gandhi, Kaushal Soni, Mayur Wanjari, Gaurav Mittal

“…GBS grown in vaginal culture was highly sensitive to benzyl penicillin and other penicillins, cephalosporins, clindamycin, daptomycin, vancomycin, meropenem, and linezolid. …”
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Enteropathogenic Escherichia coli Associated with Diarrhea in Children in Cairo, Egypt by Iman K. Behiry, Emad A. Abada, Entsar A. Ahmed, Rania S. Labeeb

“…Four (57%) EPEC isolates were resistant to ampicillin, ticarcillin, and cotrimoxazole, and (14.3%) to the third generation cephalosporins.…”
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Determination of antibiotic resistance patterns of Vibrio parahaemolyticus from shrimp and shellfish in Selangor, Malaysia by Vengadesh Letchumanan, Nurul-Syakima Ab Mutalib, Sunny Hei Wong, Kok-Gan Chan, Learn-Han Lee

“…A notable resistance pattern was also observed to the third generation cephalosporins (cefotaxime 55.8% and ceftazidime 34%). …”
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Relationship between Antibiotic Consumption and Resistance: A Systematic Review by Asrat Agalu Abejew, Gizachew Yismaw Wubetu, Teferi Gedif Fenta

“…Enterococcus faecium (59.4%), A. baumannii (52.6%), and P. aeruginosa (48.6%) were the most common antibiotic-resistant bacteria. Cephalosporins (76.8%), penicillin (58.3%), and aminoglycosides (52%) were commonly involved antibiotics in ABR. …”
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A rare neurosurgical emergency: case report of spontaneous lumbar subdural empyema by Svetozar Stanković, Milan Lepić, Ivan Bogićević, Jadranka Stanković, Goran Pavlicević

“…Initial broad-spectrum antibiotic therapy was followed by targeted therapy (vancomycin and levofloxacin) for three weeks, and then oral cephalosporins for four weeks. Laboratory parameters normalized, and the patient reported pain relief with no symptom relapses over six months. …”
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