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921
[18F]FDG PET-Based Radiomics and Machine Learning for the Assessment of Gliomas and Glioblastomas: A Systematic Review
Published 2025-01-01“…Signatures, including radiomics analysis and ML, generally demonstrated a possible diagnostic value to assess different characteristics of gliomas and GBMs, such as the methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) promoter, the isocitrate dehydrogenase (IDH) genotype, alpha thalassemia/mental retardation X-linked (ATRX) mutation status, proliferative activity, differential diagnosis with solitary brain metastases or primary central nervous system lymphoma, and prognosis of these patients. …”
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922
Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications
Published 2014-01-01“…The development and maturation of the central nervous system (CNS) through childhood is tightly regulated by intrinsic, paracrine, endocrine, and external modulators, and perturbations in any of these factors, including those related to adrenal hormone imbalance, could result in consequences that affect the structure and function of the paediatric brain. …”
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923
Therapeutic Drug Monitoring-Guided Linezolid Therapy for the Treatment of Multiple Staphylococcal Brain Abscesses in a 3-Month-Old Infant
Published 2024-12-01“…Brain abscesses are invasive infections of the central nervous system with a high level of treatment complexity especially in pediatric patients. …”
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924
Cost-effectiveness of oral versus injectable disease modifying therapies in relapsing multiple sclerosis: a systematic review analysis
Published 2024-10-01“…Abstract Background Multiple sclerosis (MS) is a chronic and progressive neurological autoimmune disease that affects the central nervous system. There are two types of drugs used to treat this disease: injectable and oral drugs. …”
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925
Upper arm deep vein thrombosis in a patient with active lupus
Published 2024-12-01“…Patients present with clinical features ranging from arthritis and arthralgias (over 90% of patients with SLE) to life-threatening hematologic, or central nervous system involvement. Individuals have an increased risk of arterial and/or venous thrombosis where the most important risk factor is the presence of antiphospholipid antibodies. …”
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926
Case report: Adult case of A20 haploinsufficiency suspected as neuro-Behçet disease
Published 2025-01-01“…Patients with A20 haploinsufficiency (HA20) presenting with central nervous system (CNS) symptoms are rare, and available reports are limited. …”
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927
Anti-Inflammatory and Antinociceptive Activities of Bufalin in Rodents
Published 2014-01-01“…The antinociceptive activities were evaluated by acetic acid-induced writhing, formalin, and hot-plate tests; open-field test investigated effects on the central nervous system. Our data showed that bufalin (0.3 and 0.6 mg/kg, i.p.) potently decreased carrageenan-induced paw edema. …”
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928
Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins
Published 2006-01-01“…Several properties of α-melanocyte stimulating hormone (α-MSH) suggested that it could be a natural antimicrobial peptide. α-MSH is a primordial peptide that appeared during the Paleozoic era, long before adaptive immunity developed and, like natural antimicrobial molecules, is produced by barrier epithelia, immunocytes, and within the central nervous system. α-MSH was discovered to have antimicrobial activity against two representative pathogens, Staphylococcus aureus and Candida albicans. …”
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929
Kejadian Gangguan Depresi pada Penderita HIV/AIDS yang Mengunjungi Poli VCT RSUP Dr. M. Djamil Padang Periode Januari - September 2013
Published 2014-05-01“…Etiology may be cause of psychososcial factor or the effect of HIV agent that infected central nervous system. In order to prevent depression disorders is by the utilization VCT (Voluntary Counseling and Testing) Clinic This study aims to describe the incident rate of depressive disorder among people living with HIV/AIDS visited VCT clinic at RSUP DR. …”
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930
Design of Upper Limb Active Rehabilitation System Based on Somatosensory Interaction Technology and Reliability and Validation Analysis
Published 2023-06-01“…Based on the plasticity of the central nervous system, Brunnstrom theory, motor re-learning, and other rehabilitation theories, this study designed the virtual games in line with the characteristics of upper limb motor dysfunction after stroke. …”
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931
Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation
Published 2020-01-01“…Although neural stem cells (NSCs) could migrate towards lesions after central nervous system (CNS) injury, the migration ability always is restricted due to the disturbed composition and density of the adhesion ligands and extracellular matrix (ECM) gradient after CNS injury. …”
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932
SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells
Published 2017-01-01“…SDF-1 and its primary receptor, CXCR4, are highly expressed in the embryonic central nervous system (CNS) and play a crucial role in brain architecture. …”
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933
Experimental Autoimmune Encephalomyelitis Development Is Aggravated by Candida albicans Infection
Published 2015-01-01“…Multiple sclerosis (MS) is an inflammatory/autoimmune disease of the central nervous system (CNS) mainly mediated by myelin specific T cells. …”
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934
Sindrom Koroner Akut dengan Komplikasi Udem Paru Akut dan Henti Jantung
Published 2015-05-01“…Disorders of the central nervous system iss the cause of high<br />mortality in patients who survived cardiac arrest and resuscitation. …”
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935
Gut Microbiota and Its Impact on Brain Function and Mental Health
Published 2025-02-01“…Recent research reveals that microbiota not only supports metabolic and immune functions but also influences central nervous system (CNS) regulation via the gut-brain axis, a two-way communication system. …”
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936
Preliminary Assessment of Reference Region Quantification and Reduced Scanning Times for [18F]SynVesT-1 PET in Parkinson’s Disease
Published 2023-01-01“…Synaptic density in the central nervous system can be measured in vivo using PET with [18F]SynVesT-1. …”
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937
Assessing the antiproliferative effect of biogenic silver chloride nanoparticles on glioblastoma cell lines by quantitative image‐based analysis
Published 2021-08-01“…Abstract Glioblastoma is the most life‐threatening tumour of the central nervous system. Temozolomide (TMZ) is the first‐choice oral drug for the treatment of glioblastoma, although it shows low efficacy. …”
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938
Epidemiology and clinical features of childhood malignant solid tumors in a single center in southwest China over 24 years
Published 2025-01-01“…The top 3 malignant solid tumors by incidence rate were central nervous system (CNS) tumors (21.8%), neuroblastoma (17.8%), and lymphoma (13.9%). …”
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939
Detection of Phosphorylated Alpha-Synuclein in the Muscularis Propria of the Gastrointestinal Tract Is a Sensitive Predictor for Parkinson’s Disease
Published 2020-01-01“…Lewy bodies and neurites, the pathological hallmarks of PD, are found in the enteric nervous system (ENS) as well as the central nervous system. Constipation is a well-documented premotor symptom in PD, and recent reports have demonstrated Lewy pathology in gastrointestinal (GI) tissues of PD patients prior to the onset of motor symptoms. …”
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940
Identification of critical biomarkers and immune landscape patterns in glioma based on multi-database
Published 2025-01-01“…Abstract Purpose Glioma is the most prevalent tumor of the central nervous system. The poor clinical outcomes and limited therapeutic efficacy underscore the urgent need for early diagnosis and an optimized prognostic approach for glioma. …”
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