Central Nervous System Lymphoma: The Great Mimicker—A Single-Institution Retrospective Study by Danielle A. Bazer, Ewa Zabrocka, Nicholas Koroneos, Agnieszka Kowalska

“…Background. Primary central nervous system lymphoma (PCNSL) is a rare, aggressive form of non-Hodgkin lymphoma contained in the brain and the spinal cord as well as the meninges, cranial nerves, eyes, and cerebrospinal fluid (CSF). …”
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Evidence of Direct Toxicological Effects of Scorpion Venom on Central Nervous System in Tunisian Children by Mabrouk Bahloul, Basma Souissi, Olfa Turki, Mariem Dlela, Khaireddine Ben Mahfoudh, Mounir Bouaziz

“…The direct action of scorpion venom on the central nervous system can explain partly these neurological disorders. …”
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Treatment Sequencing in a Chronic Lymphocytic Leukemia Patient with Central Nervous System Involvement by Filipa Mousinho, Tatiana Mendes, Paula Sousa e Santos, Maria João Acosta, José Pereira, Maria Arroz, Cândido Silva, Ana Paula Azevedo, Rita Oliveira, Martinha Chorão, Fernando Lima

“…This case describes the treatment of a patient with CLL and symptomatic compromise of the central nervous system. Our results suggest that a combination of chemotherapy, radiotherapy, and ibrutinib, administered sequentially over a 2-year period, led to a near-complete resolution of the cerebral spinal fluid neoplastic infiltration. …”
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Fluorescent Particles Based on Aggregation-Induced Emission for Optical Diagnostics of the Central Nervous System by Shan Liu, Jinkuan Liu, Xue Li, Xiaoxin Du, Cheng Yin, Yong Luo, Chenzhong Li

“…AIEgens offer promising opportunities for imaging the central nervous system (CNS), including nerve cells, neural tissues, and blood vessels. …”
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Retinal Electrophysiology Is a Viable Preclinical Biomarker for Drug Penetrance into the Central Nervous System by Jason Charng, Zheng He, Algis J. Vingrys, Rebecca L. Fish, Rachel Gurrell, Bang V. Bui, Christine T. Nguyen

“…To examine whether retinal electrophysiology is a useful surrogate marker of drug penetrance into the central nervous system (CNS). Materials and Methods. Brain and retinal electrophysiology were assessed with full-field visually evoked potentials and electroretinograms in conscious and anaesthetised rats following systemic or local administrations of centrally penetrant (muscimol) or nonpenetrant (isoguvacine) compounds. …”
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Enhancing Plasticity of the Central Nervous System: Drugs, Stem Cell Therapy, and Neuro-Implants by Alice Le Friec, Anne-Sophie Salabert, Carole Davoust, Boris Demain, Christophe Vieu, Laurence Vaysse, Pierre Payoux, Isabelle Loubinoux

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High-Dose Methotrexate for the Treatment of Relapsed Central Nervous System Erdheim-Chester Disease by Prahlad Ho, Carole Smith

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Multicomponent reactions driving the discovery and optimization of agents targeting central nervous system pathologies by Lucía Campos-Prieto, Aitor García-Rey, Eddy Sotelo, Ana Mallo-Abreu

“…In this review, we focus on central nervous system (CNS) disorders, particularly Alzheimer's disease, Parkinson's disease, schizophrenia, depression, and epilepsy, where MCRs have contributed to the development of promising ligands in recent years. …”
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Local Overexpression of Interleukin-11 in the Central Nervous System Limits Demyelination and Enhances Remyelination by Anurag Maheshwari, Kris Janssens, Jeroen Bogie, Chris Van Den Haute, Tom Struys, Ivo Lambrichts, Veerle Baekelandt, Piet Stinissen, Jerome J. A. Hendriks, Helena Slaets, Niels Hellings

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Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism by Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist

“…However, it remains unclear how this compartmentalized cell death process is orchestrated in the central nervous system (CNS). The establishment of a CNS axotomy model (using modified 3D LUHMES cultures) allowed us to study metabolic control of ND in human midbrain-derived neurons without the use of toxicants or other direct disturbance of cellular metabolism. …”
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Publisher Correction: NET formation-mediated in situ protein delivery to the inflamed central nervous system by Yina Wu, Jinwon Park, Quoc-Viet Le, Junho Byun, Jaehyun Choi, Enzhen Xu, Jaiwoo Lee, Yu-Kyoung Oh

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Magnetic Resonance Imaging Lesions in the Central Nervous System of a Dog with Canine Monocytic Ehrlichiosis by Linda G. Lang, John F. Griffin, Jonathan M. Levine, Edward B. Breitschwerdt

“…This report describes MRI central nervous system findings in a dog with ehrlichiosis.…”
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Evaluation of Novel Stereotactic Cannula for Stem Cell Transplantation against Central Nervous System Disease by Masahito Kawabori, Aki Tanimori, Shinri Kitta, Hideo Shichinohe, Kiyohiro Houkin

“…Cell therapy for central nervous system (CNS) disorders is beginning to prove its safety and efficiency. …”
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Successful Use of Ertapenem for the Treatment of Enterobacter cloacae Complex Infection of the Central Nervous System (CNS) by Sunish Shah, Dayna McManus, Jeffrey E. Topal

“…This report suggests ertapenem may be a viable option for central nervous system infections; however, further study is needed.…”
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Molecular Mechanisms and Therapeutic Prospects of Immunotherapy and Targeted Therapy in Primary Central Nervous System Lymphoma by Lin Zhong MM, Anqing Lu MB, Xiyue Lu MM, Xiaoyin Liu MD, Lujia Cao MM, Shihong Zhu MM, SiJun Diao MM, Xu Cheng MM, Hongwei Wu MB, Jing Chen MD

“…Primary central nervous system lymphoma (PCNSL) is a very rare extranodal non-Hodgkin's lymphoma confined to the brain, eyes, spinal cord, and cerebrospinal fluid (CSF). …”
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Distribution of Receptor Activity Modifying Protein (RAMP) mRNAS in the Rat Central Nervous System by K. R. Oliver, A. M. Kinsey, N. Keyvan-Fouladi, R. Heavens, A. Wainwright

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Case Report: Diagnosis and treatment of incontinentia pigmenti with central nervous system anomalies in one patient by Yun Li, Junbin Hong, Shangge Xu, Tong Zhou, Xiaolan Xiao, Jinghua Yang, Yiting Chen

“…Molecular genetic testing was conducted to identify IKBKG mutations, and the case was finally diagnosed with incontinentia pigmenti complicated by central nervous system anomalies. She was treated with oral levetiracetam (10 mg/kg/day, administered every 12 h) to control her recurrent seizures, and prednisone (1 mg/kg/day, once a day) for anti-inflammatory effects.ConclusionAfter nine months, her skin lesions have resolved, with only a few newly developed erythematous papules and areas of hyperpigmentation being evident. …”
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Three-Dimensional Organoid System Transplantation Technologies in Future Treatment of Central Nervous System Diseases by NaiLi Wei, ZiFang Quan, Hailiang Tang, JianHong Zhu

“…Besides, emerging researches on neural organogenesis promote the application of 3D organoid system transplantation in treating central nervous system (CNS) diseases. Present review will categorize current researches on organogenesis into three approaches: (a) stepwise, direct organization of region-specific or population-enriched neural organoid; (b) assemble and direct distinct organ-specific progenitor cells or stem cells to form specific morphogenesis organoid; and (c) assemble embryoid bodies for induction of multilayer organoid. …”
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Circulus arteriosus formation in cat brain by Marcelo Salvador Gomes, Gabriel Pinto Dias, Mauricio Portes Santos Sobrado Silva, Clarice Machado dos Santos, Marcelo Abidu-Figueiredo

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A Nomogram for Predicting Overall Survival in Primary Central Nervous System Lymphoma: A Retrospective Study by Ling Y, Miao X, Zhou X, Ma J, Lin Z, Li Q, Zhang M, Ma Y, Chen B

“…Yunan Ling,* Xiaqi Miao,* Xiang Zhou,* Jingjing Ma, Zhiguang Lin, Qing Li, Mengxue Zhang, Yan Ma, Bobin Chen Department of Hematology, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Bobin Chen, Department of Hematology, Huashan Hospital, Fudan University, 12 Urumuqi Road (Middle), Shanghai, 200040, People’s Republic of China, Email bbchen@fudan.edu.cnPurpose: Current prognostic scoring systems for newly diagnosed primary central nervous system lymphoma (PCNSL), such as IELSG prognostic score and MSKCC prognostic score, are widely used but have limitations in clinical practice. …”
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