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721
Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?
Published 2012-01-01“…Studies in mouse models have shown that the kinases of the c-Abl family play a role in the development of the central nervous system. Recent reports show that aberrant c-Abl activation causes neuroinflammation and neuronal loss in the forebrain of transgenic adult mice. …”
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722
Movement in the Shadow of Sadness: How Physical Activity Supports the Fight Against Depression
Published 2025-02-01“…Regular moderate exercise is an effective method to prevent central fatigue and enhance the adaptability of the central nervous system. This paper explores the complex impact of physical activity on mental health and cognitive function, emphasizing its vital role in supporting the therapy of neurological and psychiatric disorders. …”
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723
A computational approach to drug design for multiple sclerosis via QSPR modeling, chemical graph theory, and multi-criteria decision analysis
Published 2025-01-01“…Abstract Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system with an unknown etiology. While disease-modifying therapies can slow progression, there is a need for more effective treatments. …”
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724
A Rare Case of Fatal Hemorrhagic Stroke in a Young Female with Early Mixed Connective Tissue Disease
Published 2021-01-01“…Mixed connective tissue disease (MCTD) often presents as a slow progressive illness with low morbidity and mortality. Serious central nervous system disease is uncommon, and fatal outcomes are rarely seen. …”
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725
Expanded Use of Vorasidenib in Non-Enhancing Recurrent CNS WHO Grade 3 Oligodendroglioma
Published 2025-01-01“…<b>Background/Objectives</b>: Anaplastic oligodendrogliomas (AOs) are central nervous system (CNS) World Health Organization (WHO) grade 3 gliomas characterized by isocitrate dehydrogenase (IDH) mutation (m)IDH and 1p/19q codeletion. …”
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726
The effect of a single administration of streptozotocin on hippocampus metabolites in NODSCID mice
Published 2018-08-01“…The persistent hyperglycemia accompanying the development and course of type 1 diabetes mellitus (T1DM) can affect the func-tional and structural levels of the organization of the central nervous system. These changes may be mediated by metabolic aberrations. …”
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727
Carvacrol Essential Oil as a Neuroprotective Agent: A Review of the Study Designs and Recent Advances
Published 2024-12-01“…Our review provides useful evidence about the neuroprotective potential of CV; however, a lack of studies was observed regarding CV encapsulation in proper dosage forms, in particular nanoparticles, which could be further explored for CV delivery to the central nervous system.…”
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728
Investigating Feasibility of C. I. direct Yellow 50 dye Degradation and Detoxicification in Synthetic Aquatic Solution Effluent by UVA/TiO2 Nanophotocatalytic process using Daphnia...
Published 2023-06-01“…Introduction and Aims: Compounds containing dye are toxic, carcinogenic and mutagenic for aquatic organisms and lead to mutagenicity, carcinogenicity, and dysfunction of human beings’ kidney, liver, brain, reproductive system and central nervous system. Advanced oxidation processes can remove pollutants faster than other processes due to active hydroxyl radical production. …”
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729
Dehydration-Induced Anorexia Reduces Astrocyte Density in the Rat Corpus Callosum
Published 2015-01-01“…Glial cells, the major population of nerve cells in the central nervous system, play a crucial role in supplying energy to the neurons. …”
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730
Ultrastructural changes in the common carotid artery in terms of age and gender-related in Rat model
Published 2025-02-01“…A condition like atherosclerosis or thrombosis in the circulatory system results in permanent harm to structures like the central nervous system, heart and even fatality. Although the pathologies observed in the vessels are commonly attributed to the generation of atheromas, it has been recognised in recent years that changes in the tunica intima and tunica media lead to impaired vascular function without the formation of atheromas. …”
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731
Neurophysiological Endophenotypes, CNS Disinhibition, and Risk for Alcohol Dependence and Related Disorders
Published 2007-01-01“…We will present our recent genetic findings related to brain oscillations and Central Nervous System (CNS) disinhibition.…”
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732
Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake
Published 2021-01-01“…Vitamin C (ascorbic acid: AA) uptake in neurons occurs via the sodium-dependent vitamin C transporter-2 (SVCT2), which is highly expressed in the central nervous system (CNS). During chronic neuroinflammation or infection, CNS levels of lipopolysaccharide (LPS) and LPS-induced tumor necrosis factor-α (TNFα) are increased. …”
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733
Surgical Orthodontic Treatment of a Patient Affected by Type 1 Myotonic Dystrophy (Steinert Syndrome)
Published 2017-01-01“…This multisystemic form involves the skeletal muscles but affects also the eye, the endocrine system, the central nervous system, and the cardiac system. The weakness of the facial muscles causes a characteristic facial appearance frequently associated with malocclusions. …”
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734
Association between a Primitive Brain Tumor and Cerebral Aspergillosis
Published 2012-01-01“…This infection of the central nervous system is generally the complication of an invasive aspergillosis with hematogenic scattering from pulmonary focal spots. …”
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735
Cognitive changes and quality of life in neurocysticercosis: a longitudinal study.
Published 2012-01-01“…<h4>Background</h4>Few studies have focused on the cognitive morbidity of neurocysticercosis (NCC), one of the most common parasitic infections of the central nervous system. We longitudinally assessed the cognitive status and quality of life (QoL) of patients with incident symptomatic NCC cases and matched controls.…”
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736
Withaferin A Inhibits Nuclear Factor-κB-Dependent Pro-Inflammatory and Stress Response Pathways in the Astrocytes
Published 2015-01-01“…Several lines of evidence suggest that astrocytes play a key role in modulating the immune responses of the central nervous system (CNS) to infections, injuries, or pathologies. …”
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737
A Master-Slave Haptic System for Neurosurgery
Published 2011-01-01“…In particular, medical robotics has found fruitful ground in neurosurgical applications, since the high functional density of the central nervous system requires strict accuracy constraints on tool positioning. …”
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738
CNS resident macrophages exhibit region-specific states and immunogenic responses during Rbpj-deficient brain arteriovenous malformation
Published 2025-01-01“…Abstract Microglia are heterogeneous macrophage cells that serve as the central nervous system’s resident immune cells. During neuro-related diseases, CNS resident macrophages change their molecular, cellular, and functional properties—that collectively define “states”—in response to specific neural perturbations. …”
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739
Role of insulin-like growth factor-2 in Alzheimer’s disease induced memory impairment and underlying mechanisms
Published 2025-01-01“…Insulin-like growth factor-2 (IGF2), which is widely expressed in the central nervous system (CNS), has emerged as a crucial mechanism of synaptic plasticity and learning and memory, and many studies have indicated that this neurotrophic peptide is a viable candidate for treating and preventing AD-induced cognitive decline. …”
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740
Studies of clinical symptoms of panleukopenia in cats in the Donetsk People’s Republic
Published 2020-06-01“…The disease is characterized by gastrointestinal tract, central nervous system, hematopoietic tissue lesions. The paper describes the clinical signs of panleukopenia in cats in the territory of the Donetsk People’s Republic. …”
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