Enhancement of Latent Inhibition by Chronic Mild Stress in Rats Submitted to Emotional Response Conditioning by Liana Lins Melo, Elenice A. de Moraes Ferrari, Nancy Airoldi Teixeira, Guy Sandner

“…Such LI potentiation after CMS may be related to dopamine (DA) neurotransmission reduction in the central nervous system.…”
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Superficial Siderosis and Anticoagulation Therapy: Different Presentations, Different Outcomes by Rui Duarte Barreto, Luís Ruano, Vítor Tedim Cruz, Carlos Veira, Paula Coutinho

“…Superficial siderosis is a potentially manageable neurodegenerative disorder, caused by chronic subarachnoid haemorrhage and iron deposition along the central nervous system surfaces. Association with oral anticoagulant therapy is well known, but its definite role as a causative agent is yet to be clarified. …”
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Waldenstrom’s Macroglobulinemia: A Report of Two Cases, One with Severe Retinopathy and One with Renal Failure by Naoko Kudo, Masakatsu Usui, Yukiharu Nakabo, Ken-ichi Yoshida, Kenji Miki, Takashi Osafune, Keisuke Nishimura, Shinsaku Imashuku

“…We report here two cases of Waldenstrom’s macroglobulinemia (WM), one with central nervous system (CNS) symptoms and severe retinopathy and one with renal failure. …”
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Tumor Necrosis Factor Alpha Mediates GABAA Receptor Trafficking to the Plasma Membrane of Spinal Cord Neurons In Vivo by Ellen D. Stück, Randolph N. Christensen, J. Russell Huie, C. Amy Tovar, Brandon A. Miller, Yvette S. Nout, Jacqueline C. Bresnahan, Michael S. Beattie, Adam R. Ferguson

“…The proinflammatory cytokine TNFα contributes to cell death in central nervous system (CNS) disorders by altering synaptic neurotransmission. …”
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Early Neural Cell Death Is an Extensive, Dynamic Process in the Embryonic Chick and Mouse Retina by Teresa Chavarría, Jimena Baleriola, Raquel Mayordomo, Flora de Pablo, Enrique J. de la Rosa

“…Orchestrated proliferation, differentiation, and cell death contribute to the generation of the complex cytoarchitecture of the central nervous system, including that of the neuroretina. …”
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Review of osteokines in spinal cord injury: potential biomarkers during rehabilitation by Jing Liu, Jingyi Yang, Qi Wu, Zixuan Fang, Tong Wang, Zun Wang, Daoming Xu

“…Osteokines, secreted from bone tissue, could play multiple roles in regulating bone density, muscle mass, glucose metabolism, and functions of the central nervous system-changes in the osteokine levels after SCI have been detected. …”
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The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis by Song Hu, Yundong Wang, Hongbing Li

“…Firstly, the vagus nerve senses and regulates local or systemic inflammation by means of the Cholinergic Anti-inflammatory Pathway (CAP) and activation of α7-nicotinic acetylcholine receptors (α7nAChRs); thus, α7nAChRs play important roles for the central nervous system (CNS) to modulate peripheral inflammation; secondly, the activation of muscarinic acetylcholine receptors 1 (M1AChRs) in the forebrain can affect the neurons of the Medullary Visceral Zone (MVZ), the core of CAP, to regulate systemic inflammation and immunity. …”
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Intracranial ewings sarccoma mimicking middle 1/3rd parasagittal meningioma by Sharad Pandey, Pankaj Kumar, Purnima Paliwal, Achal Saxena, Sumit Deshpande, N. Monica

“…Primary Ewing’s Sarcoma affecting the central nervous system (CNS) is rare, which is commonly intraparenchymal located either supratentorial or in the spinal cord. …”
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Application of psychobiotics in clinical treatment of mental disorders: Neurodevelopmental disorders, neurodegenerative diseases, depression and anxiety by Jingwei Cui, Wenxin Wang, Yue Tang, Siyuan Feng, Hong Liu, Zikai Hao

“…Neurons in the enteric nervous system directly interact with neurotransmitters, short‐chain fatty acids (SCFAs), gut hormones, and anti‐inflammatory cytokines produced by the gut microbiota, thereby affecting signal transmission in the central nervous system. Unlike traditional probiotics, psychobiotics have the capacity to generate or stimulate the host to produce neurotransmitters, SCFAs, gut hormones, and anti‐inflammatory cytokines. …”
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Parkinsonism and Sjögren’s Syndrome: A Fortuitous Association or a Shared Immunopathogenesis? by Mariem Kchaou, Nadia Ben Ali, Intissar Hmida, Saloua Fray, Hela Jamoussi, Mohamed Jalleli, Slim Echebbi, Afef Achouri, Samir Belal

“…The Sjögren Syndrome (SS) can include various manifestations of central nervous system impairment. Extrapyramidal signs are known to be very rare and unusually discovered on early onset in this pathology. …”
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Optic Neuritis in an Adult Patient with Chickenpox by Ana Rita Azevedo, Rita Simões, Filipe Silva, Susana Pina, Cristina Santos, Peter Pêgo, Filomena Silva, Susana Teixeira

“…Central nervous system involvement in a patient with primary infection with Varicella zoster virus is rare, especially in the immunocompetent adult. …”
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Fetal Alcohol Syndrome: Impact on Neurodevelopment, Diagnosis, Early Intervention and Motor Disorders in Children under 3 Years by Sabina Adamczyk, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Gabriela Trestka, Urszula Zelik, Jakub Dziewic, Joanna Śnieżna, Wojciech Florczak, Wiktoria Domino, Karol Dzwonnik

“…The consequences are particularly profound on the central nervous system (CNS), where damage to structures like the cerebellum can lead to motor dysfunctions, balance issues, and cognitive impairments. …”
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The Influence of Depression and Anxiety on Neurological Disability in Multiple Sclerosis Patients by Vitalie Văcăraș, Veronica Văcăraș, Cristina Nistor, Daniela Văcăraș, Adrian Nicolae Opre, Petronela Blaga, Dafin F. Mureșanu

“…Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS), affecting mostly young-aged people. …”
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Expression of catecholaminergic genes in the midbrain and prepulse inhibition in rats with a genetic catatonia by M. A. Ryazanova, O. I. Prokudina, V. S.  Plekanchuk, T. A. Alekhina

“…For the first time, a decrease of PPI in GC rats compared with WAG rats was shown, both with a prepulse power of 75 dB and at 85 dB, which may indicate a violation of filtration of sensorimotor information into the central nervous system in GC rats. Real-time PCR showed a decrease in mRNA level of Adra1A in intact rats with genetic catatonia when compared to control WAG rats. …”
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A comprehensive review of remimazolam for sedation by Nazir Noor, Rhorer Legendre, Alexandra Cloutet, Ahish Chitneni, Giustino Varrassi, Alan D. Kaye

“…This is provided by the benzodiazepine molecule binding and causing a conformational change to the chloride ion channel to cause hyperpolarization and thus inhibition of the central nervous system. Each type of benzodiazepine has a preferred role within the realm of medicine. …”
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Methods to address functional unblinding of raters in CNS trials by Steven D. Targum, William P. Horan, Vicki G. Davis, Alan Breier, Stephen K. Brannan

“…Abstract Treatment-emergent adverse events (TEAEs) associated with the unique properties of a pharmaceutical product may functionally unblind clinician ratings, obscure true medication effects, and affect confidence about clinical trial results. Central nervous system studies are particularly susceptible to functional unblinding because they rely on relatively subjective symptom assessments. …”
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Mitochondrial function in patients affected with fibromyalgia syndrome is impaired and correlates with disease severity by Chiara Macchi, Andrea Giachi, Isabella Fichtner, Silvia Pedretti, Piercarlo Sarzi-Puttini, Nico Mitro, Alberto Corsini, Massimiliano Ruscica, Roberta Gualtierotti

“…Additionally, we found a mild correlation between the widespread pain index and the BHI, possibly indicating that the altered mitochondrial function, in these patients, narrows musculoskeletal rather than central nervous system involvement.…”
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Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase by Lies De Groef, Manuel Salinas-Navarro, Griet Van Imschoot, Claude Libert, Roosmarijn E. Vandenbroucke, Lieve Moons

“…Matrix metalloproteinases (MMPs) have been designated as both friend and foe in the central nervous system (CNS): while being involved in many neurodegenerative and neuroinflammatory diseases, their actions appear to be indispensable to a healthy CNS. …”
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Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo by Chien-Wei Feng, Nan-Fu Chen, Te-Fu Chan, Wu-Fu Chen

“…However, few studies have investigated the role of PTP1B in the central nervous system. Our study showed that suramin, an inhibitor of PTP1B, could improve neuronal damage. …”
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A Case Report of Acute Esotropia in a Young Woman following Heroin Withdrawal by Bethel Shiferaw, Ebisa Bekele, Sara Syed, Lu Fan, Nirav Patel, Samia Qazi, Nicolas Biro

“…Acute onset esotropia is rare and must be investigated right away to exclude central nervous system pathologies, where no opiates use is reported. …”
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