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621
Motor Sequence Learning across Multiple Sessions Is Not Facilitated by Targeting Consolidation with Posttraining tDCS in Patients with Progressive Multiple Sclerosis
Published 2021-01-01“…These patients may, therefore, particularly benefit from interventions that augment training-induced plasticity of the central nervous system. In this cross-sectional double-blind cross-over pilot study, effects of transcranial direct current stimulation (tDCS) on motor sequence learning were examined across four sessions on days 1, 3, 5, and 8 in 16 patients with progressive MS. …”
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622
Recurrent Nasal-Type Extranodal Natural Killer/T-Cell Lymphoma with Meningeal Involvement
Published 2021-01-01“…It has an aggressive behavior, known for predilection to metastasize to different organs. Central nervous system (CNS) spread from a primary location has been reported. …”
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623
The possible effects of chili peppers on ADHD in relation to the gut microbiota
Published 2025-02-01“…Among them, capsaicin (8-methyl N-vanillyl-6-noneamide, CAP), as a key active component of peppers, has been shown to have potential therapeutic effects on central nervous system (CNS) diseases such as Parkinson’s disease, epilepsy, and depression. …”
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624
Just a SNP away: The future of in vivo massively parallel reporter assay
Published 2025-02-01“…Given the complexity of the central nervous system and its widespread interactions with all other organ systems, our understanding of neuropsychiatric disorder-associated noncoding variants would be greatly advanced by studying their functional impact in the intact brain. …”
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625
The Mechanism of Metabolic Influences on the Endogenous GLP-1 by Oral Antidiabetic Medications in Type 2 Diabetes Mellitus
Published 2020-01-01“…In this review, we discuss the metabolic relationships between oral antihyperglycemic drugs from the aspect of gut, microbiota, hormones, β cell function, central nervous system, and other cellular mechanisms.…”
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626
Whole organism and tissue-specific analysis of pexophagy in Drosophila
Published 2025-02-01“…Specific drivers were used to visualize pexophagy in neurons, and to demonstrate that specific depletion in the larval central nervous system of Hsc70-5, the Drosophila homologue of the chaperone HSPA9/mortalin, led to a substantial elevation in pexophagy.…”
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627
Primary Gliosarcoma of the Cerebellum in a Young Pregnant Woman: Management Challenges and Immunohistochemical Features
Published 2019-01-01“…Gliosarcoma (GS) represents a rare, high-grade (WHO Grade IV), central nervous system neoplasm, characterized by a very poor prognosis. …”
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628
Disseminated tuberculosis masquerading as a psychiatric illness—A case report
Published 2024-12-01“…We report a patient who presented primarily for psychiatric symptoms of three months’ duration, which later turned out to be a case of DTB involving the central nervous system as well as the spine and lungs. Case Presentation: An elderly lady with subacute onset and worsening behavioural changes of three months’ duration was referred for exclusion of organic brain disease. …”
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629
Recurrent CSPs after Transcranial Magnetic Stimulation of Motor Cortex in Restless Legs Syndrome
Published 2012-01-01“…Further research is needed to clarify the role of the intramuscular recording technique and especially the role of the subcortical generators in the feedback regulation of the central nervous system in RLS.…”
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630
Chemokine Expression in Human Astrocytes in Response to Shiga Toxin 2
Published 2012-01-01“…Approximately, 30% of patients with HUS suffer from complications in the central nervous system (CNS), which is an important determinant of mortality in such patients. …”
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631
High-Affinity Detection of Alpha-Synuclein by Aptamer-Gold Conjugates on an Amine-Modified Dielectric Surface
Published 2019-01-01“…Parkinson’s disease (PD) is a progressive health issue and influences an increasingly larger number of people, especially at older ages, affecting the central nervous system (CNS). Alpha-synuclein is a biomarker closely correlated with the CNS and PD. …”
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632
Learning a Second Language in Adulthood Changes Subcortical Neural Encoding
Published 2020-01-01“…Second language learning has been shown to impact and reshape the central nervous system, anatomically and functionally. Most of the studies on second language learning and neuroplasticity have been focused on cortical areas, whereas the subcortical neural encoding mechanism and its relationship with L2 learning have not been examined extensively. …”
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633
The Distinct Functions of Dopaminergic Receptors on Pain Modulation: A Narrative Review
Published 2021-01-01“…In the present report, we have reviewed the analgesic effects of different dopamine receptors, particularly D1 and D2 receptors, in different regions of the central nervous system, including the spinal cord, striatum, nucleus accumbens (NAc), and periaqueductal gray (PAG). …”
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634
Adrenoleukodystrophy: Symptoms, Treatment and Newborn Screening. Literature Review and Clinical Case
Published 2024-12-01“…After summarising the literature, 6 main groups of symptoms are suggested: behavioural changes, hearing and visual impairment, neuromuscular system disorders, central nervous system impairment, nonspecific and other non-neurological symptoms. …”
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635
PET Study in a Patient with Spinocerebellar Degeneration before and after Long-Term Administration of Thyrotropin Releasing Hormone
Published 1996-01-01“…We speculate that the chronic effect of TRH was not necessarily due to an improvement of cerebellar function, because TRH receptors are widely distributed throughout the central nervous system.…”
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636
Exploring the interaction between the gut microbiota and cyclic adenosine monophosphate-protein kinase A signaling pathway: a potential therapeutic approach for neurodegenerative d...
Published 2025-11-01“…The interaction between the gut microbiota and cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) signaling pathway in the host’s central nervous system plays a crucial role in neurological diseases and enhances communication along the gut–brain axis. …”
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637
Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case re...
Published 2025-12-01“…Background: Progressive multifocal leukoencephalopathy (PML) is characterized by demyelination in the central nervous system. It is caused by infection with human polyomavirus 2 and has a poor prognosis. …”
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638
Osmotic Demyelination Syndrome due to Rhabdomyolysis and Hyperosmolar Hyperglycemic Syndrome following Cardiogenic Shock
Published 2021-01-01“…Osmotic demyelination syndrome (ODS) is a relatively rare disease that causes rapid demyelination, resulting in pontine and central nervous system damage with various symptoms, including impaired consciousness. …”
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639
A Tanzanian Boy with Molecularly Confirmed X-Linked Adrenoleukodystrophy
Published 2019-01-01“…In a boy with features of a progressive central nervous system condition and adrenal failure, ABCD1 gene screening was performed based on a clinical history and basic radiological features which were compatible with ALD. …”
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640
Neuromuscular and structural tendon adaptations after 6 weeks of either concentric or eccentric exercise in individuals with non-insertional Achilles tendinopathy: protocol for a r...
Published 2022-07-01“…Introduction There is limited evidence on the neural strategies employed by the central nervous system to control muscle force in the presence of non-insertional Achilles tendinopathy (NIAT). …”
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